DK1881064T3 - HCV-anti-kerne monoklonalt antistof - Google Patents

HCV-anti-kerne monoklonalt antistof

Info

Publication number
DK1881064T3
DK1881064T3 DK07075928.7T DK07075928T DK1881064T3 DK 1881064 T3 DK1881064 T3 DK 1881064T3 DK 07075928 T DK07075928 T DK 07075928T DK 1881064 T3 DK1881064 T3 DK 1881064T3
Authority
DK
Denmark
Prior art keywords
monoclonal antibody
antibodies
hcv anti
core monoclonal
hcv
Prior art date
Application number
DK07075928.7T
Other languages
English (en)
Inventor
Chander Bahl
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Application granted granted Critical
Publication of DK1881064T3 publication Critical patent/DK1881064T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK07075928.7T 2001-11-05 2002-11-04 HCV-anti-kerne monoklonalt antistof DK1881064T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33745301P 2001-11-05 2001-11-05
US10/268,561 US7049060B2 (en) 2001-11-05 2002-10-10 HCV anti-core monoclonal antibodies
EP02257622A EP1308507B1 (en) 2001-11-05 2002-11-04 HCV anti-core monoclonal antibody

Publications (1)

Publication Number Publication Date
DK1881064T3 true DK1881064T3 (da) 2010-06-07

Family

ID=26953173

Family Applications (2)

Application Number Title Priority Date Filing Date
DK02257622T DK1308507T3 (da) 2001-11-05 2002-11-04 Monoklonalt antistof mod HCV-kerneantigen
DK07075928.7T DK1881064T3 (da) 2001-11-05 2002-11-04 HCV-anti-kerne monoklonalt antistof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK02257622T DK1308507T3 (da) 2001-11-05 2002-11-04 Monoklonalt antistof mod HCV-kerneantigen

Country Status (9)

Country Link
US (1) US7049060B2 (da)
EP (3) EP2186884A3 (da)
JP (1) JP2004035534A (da)
AT (2) ATE459706T1 (da)
CA (1) CA2406240C (da)
DE (2) DE60235588D1 (da)
DK (2) DK1308507T3 (da)
ES (2) ES2295292T3 (da)
PT (2) PT1308507E (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8658773B2 (en) 2011-05-02 2014-02-25 Immunomedics, Inc. Ultrafiltration concentration of allotype selected antibodies for small-volume administration
US7902338B2 (en) 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
JP2009018990A (ja) * 2005-10-25 2009-01-29 Univ Kurume Ｃ型肝炎ウイルス由来ペプチド
US7858752B2 (en) 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
CN102448494B (zh) 2009-02-13 2016-02-03 免疫医疗公司 具有胞内可裂解的键的免疫共轭物
CN102482701B (zh) 2009-09-16 2015-05-13 免疫医疗公司 I类抗-cea抗体及其使用
IN2012DN03354A (da) 2009-12-02 2015-10-23 Immunomedics Inc
WO2012006500A2 (en) * 2010-07-08 2012-01-12 Abbott Laboratories Monoclonal antibodies against hepatitis c virus core protein
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
CA2874864C (en) 2012-08-14 2023-02-21 Ibc Pharmaceuticals, Inc. T-cell redirecting bispecific antibodies for treatment of disease
CA2884313C (en) 2012-12-13 2023-01-03 Immunomedics, Inc. Dosages of immunoconjugates of antibodies and sn-38 for improved efficacy and decreased toxicity
EP2968526A4 (en) 2013-03-14 2016-11-09 Abbott Lab ANTIGEN-ANTIBODY COMBINATION ASSAY OF HEPATITIS C VIRUS AND METHODS AND COMPOSITIONS FOR USE THEREWITH
EP3916103A1 (en) 2013-03-14 2021-12-01 Abbott Laboratories Hcv core lipid binding domain monoclonal antibodies
BR112015023355A8 (pt) 2013-03-14 2018-01-30 Abbott Lab antígenos recombinantes ns3 de hcv e mutantes dos mesmos para detecção de anticorpos aprimorada.
CN106132436B (zh) 2014-02-21 2021-06-15 Ibc药品公司 通过诱导对trop-2表达细胞的免疫应答的疾病疗法
CN106029098A (zh) 2014-02-25 2016-10-12 免疫医疗公司 人源化rfb4抗cd22抗体
WO2015200260A1 (en) 2014-06-24 2015-12-30 Immunomedics, Inc. Anti-histone therapy for vascular necrosis in severe glomerulonephritis
ES2892525T3 (es) 2014-10-07 2022-02-04 Immunomedics Inc Uso neoadyuvante de conjugados anticuerpo-fármaco
EP3286224A4 (en) 2015-04-22 2018-11-14 Immunomedics, Inc. Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells
JP6980980B2 (ja) 2015-06-25 2021-12-15 イミューノメディクス、インコーポレイテッドImmunomedics, Inc. 抗ｈｌａ‐ｄｒまたは抗ｔｒｏｐ‐２抗体と微小管阻害剤、ｐａｒｐ阻害剤、ブルトンキナーゼ阻害剤またはホスホイノシチド３‐キナーゼ阻害剤との併用は癌の治療効果を有意に改善する
EP3316885B1 (en) 2015-07-01 2021-06-23 Immunomedics, Inc. Antibody-sn-38 immunoconjugates with a cl2a linker
CN109154617B (zh) 2016-05-31 2022-08-26 豪夫迈·罗氏有限公司 用于hcv核心抗原的快速检测的预处理方法
EP3465217A1 (en) 2016-05-31 2019-04-10 Roche Diagnostics GmbH Method for serological detection of viral antigens
ES2865511T3 (es) 2017-02-02 2021-10-15 Hoffmann La Roche Inmunoanálisis que usa al menos dos agentes de unión específica a analito pegilado
KR20200032695A (ko) 2017-07-27 2020-03-26 에프. 호프만-라 로슈 아게 Hcv 항원의 다중-에피토프 융합 단백질 및 이의 용도
CN109738648B (zh) * 2018-12-29 2021-09-17 山东莱博生物科技有限公司 稳定高效表达丙型肝炎病毒核心抗原抗体的工程细胞株及其应用
JPWO2022239720A1 (da) 2021-05-10 2022-11-17

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990011089A1 (en) 1989-03-17 1990-10-04 Chiron Corporation Nanbv diagnostics and vaccines
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
ZA927837B (en) 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
FR2775690B1 (fr) 1998-03-09 2001-12-14 Bio Merieux Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc
US20030022155A1 (en) * 1999-04-14 2003-01-30 Agata Budkowska Method for detecting hepatitis c virus with hybridomas
BRPI0111731C1 (pt) * 2000-06-15 2021-07-27 Chiron Corp suporte sólido de imunoensaio, métodos de detecção de infecção pelo vírus da hepatite c (hcv) em uma amostra biológica, e de produção de um suporte sólido de imunoensaio, e, kit de teste de imunodiagnóstico
WO2003002749A2 (en) * 2001-06-26 2003-01-09 Abbott Laboratories Methods for the simultaneous detection of hcv antigens and hcv antibodies

Also Published As

Publication number Publication date
EP2186884A2 (en) 2010-05-19
PT1881064E (pt) 2010-03-31
DE60235588D1 (de) 2010-04-15
CA2406240A1 (en) 2003-05-05
EP1308507A2 (en) 2003-05-07
ES2339709T3 (es) 2010-05-24
EP2186884A3 (en) 2010-09-08
DE60224346D1 (de) 2008-02-14
ATE459706T1 (de) 2010-03-15
EP1308507A3 (en) 2003-10-22
ES2295292T3 (es) 2008-04-16
DE60224346T2 (de) 2008-12-24
CA2406240C (en) 2011-01-04
PT1308507E (pt) 2008-03-31
US20030148333A1 (en) 2003-08-07
EP1881064B1 (en) 2010-03-03
DK1308507T3 (da) 2008-05-19
JP2004035534A (ja) 2004-02-05
EP1881064A2 (en) 2008-01-23
EP1881064A3 (en) 2008-04-09
US7049060B2 (en) 2006-05-23
EP1308507B1 (en) 2008-01-02
ATE382683T1 (de) 2008-01-15

Similar Documents

Publication Publication Date Title
DK1881064T3 (da) HCV-anti-kerne monoklonalt antistof
NO2017032I1 (no) bezlotoksumab
DK1414858T3 (da) Kamelid-enkeltkæde-VHH-antistoffer, fremgangsmåde til fremstilling heraf i et pattedyr samt anvendelser heraf
ATE452147T1 (de) Antikörper mit korrigierten cdr
NO20071436L (no) Humaniserte Anti-5T4 antistoffer og Anti-5T4 antistoff/calicheamicin konjugater
ATE520716T1 (de) Humanisierter anti-cd4-antikörper mit immunsuppressiven eigenschaften
TW200516083A (en) Methods for making dual specificity antibodies
DE69230146T2 (de) Monoklonale antikörper gegen putative hcv-e2/ns1-proteine und verfahren zu ihrer verwendung
ATE480564T1 (de) Monoklonaler anti-mensch-tenascin-antikörper
NO20051715L (no) HCV assay
DE60045870D1 (de) Monoklonaler antikörper, hybridoma, immuntestverfahren und diagnosekit
DE69224134D1 (de) Monoklonale Antikörper gegen Hepatitis-C-Virus
DK0569537T3 (da) Monoklonale antistoffer mod formodede HCV-kapperegioner og fremgangsmåder til anvendelse deraf
AU2003283240A8 (en) Antibody for isolating and/or identifying mesenchymal stem cells and method for isolating and/or identifying mesenchymal stem cells
DK0556320T3 (da) Monoklonale antistoffer mod Hepatitis C-virus og fremgangsmåde til anvendelse heraf
BR0204612A (pt) Anticorpos monoclonais antinúcleo de hcv
DK0599913T3 (da) Monoklonale antistoffer mod formodet hepatitis C-virus NS5-proteiner og anvendelsesmetoder af samme
FI20011055A (fi) Heveiiniä sitovat monoklonaaliset vasta-aineet
AR037216A1 (es) Anticuerpos monoclonales antinucleares de hcv