DE69224134D1 - Monoklonale Antikörper gegen Hepatitis-C-Virus - Google Patents

Monoklonale Antikörper gegen Hepatitis-C-Virus

Info

Publication number
DE69224134D1
DE69224134D1 DE69224134T DE69224134T DE69224134D1 DE 69224134 D1 DE69224134 D1 DE 69224134D1 DE 69224134 T DE69224134 T DE 69224134T DE 69224134 T DE69224134 T DE 69224134T DE 69224134 D1 DE69224134 D1 DE 69224134D1
Authority
DE
Germany
Prior art keywords
hepatitis
virus
monoclonal antibodies
cell line
monoclonal antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69224134T
Other languages
English (en)
Other versions
DE69224134T2 (de
Inventor
Winand Johannes Antoniu Habets
Miriam Francisca Hen Klein-Rot
Theodorus Adrianus Oosterlaken
Sing Hiem Yap
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE69224134D1 publication Critical patent/DE69224134D1/de
Application granted granted Critical
Publication of DE69224134T2 publication Critical patent/DE69224134T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69224134T 1991-10-15 1992-10-14 Monoklonale Antikörper gegen Hepatitis-C-Virus Expired - Lifetime DE69224134T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91202659 1991-10-15

Publications (2)

Publication Number Publication Date
DE69224134D1 true DE69224134D1 (de) 1998-02-26
DE69224134T2 DE69224134T2 (de) 1998-07-02

Family

ID=8207945

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69224134T Expired - Lifetime DE69224134T2 (de) 1991-10-15 1992-10-14 Monoklonale Antikörper gegen Hepatitis-C-Virus

Country Status (11)

Country Link
US (1) US5595868A (de)
EP (1) EP0537856B1 (de)
JP (1) JP3335387B2 (de)
KR (1) KR100238559B1 (de)
AT (1) ATE162553T1 (de)
AU (1) AU670541B2 (de)
CA (1) CA2080548C (de)
DE (1) DE69224134T2 (de)
ES (1) ES2114547T3 (de)
FI (1) FI105275B (de)
ZA (1) ZA927837B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
US5753430A (en) * 1990-11-07 1998-05-19 Abbott Laboratories Monoclonal antibodies to hepatitis C virus and method for using same
CA2095735C (en) * 1990-11-07 2004-02-03 Smriti U. Mehta Monoclonal antibodies to hepatitis c virus and method for using same
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
CN1044384C (zh) * 1994-08-25 1999-07-28 中国药品生物制品检定所 抗丙型肝炎病毒抗原单克隆抗体细胞株建立及其单克隆抗体
US5849800A (en) * 1997-03-28 1998-12-15 The Penn State Research Foundation Use of amantadine for treatment of Hepatitis C
CA2316130A1 (en) * 1999-08-19 2001-02-19 Masanori Fukui Method for detection or determination of hcv core antigens and reagent for detection or determination for use therein
US7022323B2 (en) * 2001-06-26 2006-04-04 Progenics Pharmaceuticals, Inc. Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection
US20030232745A1 (en) * 2001-06-26 2003-12-18 Olson William C. Uses of DC-sign and DC-Signr for inhibiting hepatitis C virus infection
US7049060B2 (en) * 2001-11-05 2006-05-23 Ortho-Clinical Diagnostics, Inc. HCV anti-core monoclonal antibodies
US7858752B2 (en) * 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
JP5642972B2 (ja) 2007-02-21 2014-12-17 ユニバーシティー オブ マサチューセッツＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｍａｓｓａｃｈｕｓｅｔｔｓ Ｃ型肝炎ウイルス（ｈｃｖ）に対するヒト抗体およびその使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049686C (zh) * 1987-11-18 2000-02-23 希龙股份有限公司 非ａ和非ｂ肝炎病毒的诊断及疫苗
US5191064A (en) * 1988-09-30 1993-03-02 The Research Foundation For Microbial Diseases (Osaka University) Non-a, non-b hepatitis virus antigen peptide
HU225068B1 (en) * 1989-03-17 2006-05-29 Chiron Corp Process for producing diagnostics and vaccine of nanbh
EP0445801A3 (en) * 1990-03-08 1992-07-01 Kuraray Co., Ltd. Peptide and its use
JPH0436185A (ja) * 1990-03-28 1992-02-06 Kyowa Hakko Kogyo Co Ltd 融合抗原ポリペプチド
ZA912040B (en) * 1990-03-30 1991-12-24 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus

Also Published As

Publication number Publication date
FI924641A (fi) 1993-04-16
JP3335387B2 (ja) 2002-10-15
KR100238559B1 (ko) 2000-01-15
AU2707992A (en) 1993-04-22
AU670541B2 (en) 1996-07-25
EP0537856A1 (de) 1993-04-21
FI105275B (fi) 2000-07-14
ATE162553T1 (de) 1998-02-15
EP0537856B1 (de) 1998-01-21
CA2080548C (en) 2003-07-01
ZA927837B (en) 1994-03-11
US5595868A (en) 1997-01-21
FI924641A0 (fi) 1992-10-14
ES2114547T3 (es) 1998-06-01
KR930008155A (ko) 1993-05-21
CA2080548A1 (en) 1993-04-16
DE69224134T2 (de) 1998-07-02
JPH05260960A (ja) 1993-10-12

Similar Documents

Publication Publication Date Title
ES2106195T3 (es) Anticuerpo igg aglicosilado anti cd3.
NO980030D0 (no) Monoklonale antistoffer som binder CD40-L
DK187889A (da) Dna-forbindelser og klonende vektorer, der koder for det monoklonale antistof ks1/4, samt chimere antistoffer afledt af ks1/4 og rettet mod et humant adenocarcinoma-antigen
DK0733069T3 (da) Oprensede Primat CTLA-8-antigener og beslægtede reagenser
DE3177290D1 (de) Monoklonale antikoerper gegen hepatitis-b-virus.
DE68914244D1 (de) Monoklonaler Antikörper.
ATE382683T1 (de) Monoklonales antikörper gegen das hcv kernantigen
DE3854502D1 (de) Gegen hiv-antigene spezifischer monoklonaler antikörper.
DK0538754T3 (da) Anvendelse af antistofholdige præparater til immunundertrykkelse
DE69224134D1 (de) Monoklonale Antikörper gegen Hepatitis-C-Virus
DE3885355D1 (de) Monoklonale Antikörper.
DK1144006T3 (da) Synergistisk inhibering af HIV-1-fusion og -binding, præparater og antistoffer dertil
DE69738312D1 (de) Hepatitis b monoklonale antikörper
EP0569537A4 (en) Monoclonal antibodies to putative hcv envelope region and methods for using same
DK442888A (da) Slaegtspecifikt listeria-antigen identificeret ved hjaelp af monoklone antistoffer
DE3785795D1 (de) Monoklonale anti-menschliche magenkrebs-antikoerper.
DK0556320T3 (da) Monoklonale antistoffer mod Hepatitis C-virus og fremgangsmåde til anvendelse heraf
WO1994021812A3 (en) Hepatitis b escape mutant specific binding molecules
EP0599913A4 (de) Monoklonale antikörper gegen mutmassliche hepatitis c-virus ns5-proteine und ihre anwendungsmethoden.
NO890116D0 (no) Monoklonale antistoffer.
DE69023717D1 (de) Monoklonaler Antikörper.
DE68916088D1 (de) Anti-CPBII-monoklonaler Antikörper.
BR0204612A (pt) Anticorpos monoclonais antinúcleo de hcv

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R071 Expiry of right

Ref document number: 537856

Country of ref document: EP