ES2114547T3 - Anticuerpos monoclonales contra el virus de la hepatitis c. - Google Patents

Anticuerpos monoclonales contra el virus de la hepatitis c.

Info

Publication number
ES2114547T3
ES2114547T3 ES92203144T ES92203144T ES2114547T3 ES 2114547 T3 ES2114547 T3 ES 2114547T3 ES 92203144 T ES92203144 T ES 92203144T ES 92203144 T ES92203144 T ES 92203144T ES 2114547 T3 ES2114547 T3 ES 2114547T3
Authority
ES
Spain
Prior art keywords
hepatitis
virus
monoclonal antibodies
antibodies against
cell line
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92203144T
Other languages
English (en)
Inventor
Winand Johannes Antoniu Habets
Miriam Francisca Hen Klein-Rot
Theodorus Adrianus Oosterlaken
Sing Hiem Yap
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Application granted granted Critical
Publication of ES2114547T3 publication Critical patent/ES2114547T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE REFIERE A UNA LINEA CELULAR DE HIBRIDOMA QUE PRODUCE UN ANTICUERPO MONOCLONAL QUE TIENE ESPECIFICIDAD DE UNION PARA LOS HEPITOPOS EN LA PROTEINA DEL NUCLEO DEL VIRUS DE LA HEPATITIS C (HCV) Y UN ANTICUERPO MONOCLONAL PRODUCIDO MEDIANTE LA LINEA CELULAR DEL HIBRIDOMA.
ES92203144T 1991-10-15 1992-10-14 Anticuerpos monoclonales contra el virus de la hepatitis c. Expired - Lifetime ES2114547T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91202659 1991-10-15

Publications (1)

Publication Number Publication Date
ES2114547T3 true ES2114547T3 (es) 1998-06-01

Family

ID=8207945

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92203144T Expired - Lifetime ES2114547T3 (es) 1991-10-15 1992-10-14 Anticuerpos monoclonales contra el virus de la hepatitis c.

Country Status (11)

Country Link
US (1) US5595868A (es)
EP (1) EP0537856B1 (es)
JP (1) JP3335387B2 (es)
KR (1) KR100238559B1 (es)
AT (1) ATE162553T1 (es)
AU (1) AU670541B2 (es)
CA (1) CA2080548C (es)
DE (1) DE69224134T2 (es)
ES (1) ES2114547T3 (es)
FI (1) FI105275B (es)
ZA (1) ZA927837B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
ES2132115T3 (es) * 1990-11-07 1999-08-16 Abbott Lab Anticuerpos monoclonales contra el virus de la hepatitis c y su procedimiento de utilizacion.
US5753430A (en) * 1990-11-07 1998-05-19 Abbott Laboratories Monoclonal antibodies to hepatitis C virus and method for using same
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
CN1044384C (zh) * 1994-08-25 1999-07-28 中国药品生物制品检定所 抗丙型肝炎病毒抗原单克隆抗体细胞株建立及其单克隆抗体
US5849800A (en) * 1997-03-28 1998-12-15 The Penn State Research Foundation Use of amantadine for treatment of Hepatitis C
CA2316130A1 (en) * 1999-08-19 2001-02-19 Masanori Fukui Method for detection or determination of hcv core antigens and reagent for detection or determination for use therein
US20030232745A1 (en) * 2001-06-26 2003-12-18 Olson William C. Uses of DC-sign and DC-Signr for inhibiting hepatitis C virus infection
US7022323B2 (en) * 2001-06-26 2006-04-04 Progenics Pharmaceuticals, Inc. Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection
US7049060B2 (en) 2001-11-05 2006-05-23 Ortho-Clinical Diagnostics, Inc. HCV anti-core monoclonal antibodies
US7858752B2 (en) * 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
AU2008223561B2 (en) 2007-02-21 2013-10-03 University Of Massachusetts Human antibodies against hepatitis C virus (HCV) uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02500880A (ja) * 1987-11-18 1990-03-29 カイロン　コーポレイション Ｎａｎｂｖの診断用薬およびワクチン
US5191064A (en) * 1988-09-30 1993-03-02 The Research Foundation For Microbial Diseases (Osaka University) Non-a, non-b hepatitis virus antigen peptide
JP2656995B2 (ja) * 1989-03-17 1997-09-24 カイロン コーポレイション Ｎａｎｂｖの診断用薬
EP0445801A3 (en) * 1990-03-08 1992-07-01 Kuraray Co., Ltd. Peptide and its use
JPH0436185A (ja) * 1990-03-28 1992-02-06 Kyowa Hakko Kogyo Co Ltd 融合抗原ポリペプチド
ZA912040B (en) * 1990-03-30 1991-12-24 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus

Also Published As

Publication number Publication date
DE69224134T2 (de) 1998-07-02
ZA927837B (en) 1994-03-11
KR100238559B1 (ko) 2000-01-15
KR930008155A (ko) 1993-05-21
ATE162553T1 (de) 1998-02-15
FI924641A0 (fi) 1992-10-14
FI924641A (fi) 1993-04-16
JPH05260960A (ja) 1993-10-12
EP0537856B1 (en) 1998-01-21
FI105275B (fi) 2000-07-14
US5595868A (en) 1997-01-21
EP0537856A1 (en) 1993-04-21
JP3335387B2 (ja) 2002-10-15
CA2080548C (en) 2003-07-01
AU2707992A (en) 1993-04-22
AU670541B2 (en) 1996-07-25
DE69224134D1 (de) 1998-02-26
CA2080548A1 (en) 1993-04-16

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