ATE382683T1 - Monoklonales antikörper gegen das hcv kernantigen - Google Patents
Monoklonales antikörper gegen das hcv kernantigenInfo
- Publication number
- ATE382683T1 ATE382683T1 AT02257622T AT02257622T ATE382683T1 AT E382683 T1 ATE382683 T1 AT E382683T1 AT 02257622 T AT02257622 T AT 02257622T AT 02257622 T AT02257622 T AT 02257622T AT E382683 T1 ATE382683 T1 AT E382683T1
- Authority
- AT
- Austria
- Prior art keywords
- core antigen
- hcv core
- monoclonal antibody
- antibody against
- antibodies
- Prior art date
Links
- 101710132601 Capsid protein Proteins 0.000 title 1
- 108700039791 Hepatitis C virus nucleocapsid Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
- C07K16/109—Hepatitis C virus; Hepatitis G virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33745301P | 2001-11-05 | 2001-11-05 | |
US10/268,561 US7049060B2 (en) | 2001-11-05 | 2002-10-10 | HCV anti-core monoclonal antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE382683T1 true ATE382683T1 (de) | 2008-01-15 |
Family
ID=26953173
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02257622T ATE382683T1 (de) | 2001-11-05 | 2002-11-04 | Monoklonales antikörper gegen das hcv kernantigen |
AT07075928T ATE459706T1 (de) | 2001-11-05 | 2002-11-04 | Monoklonales antikörper gegen das hcv kernantigen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07075928T ATE459706T1 (de) | 2001-11-05 | 2002-11-04 | Monoklonales antikörper gegen das hcv kernantigen |
Country Status (9)
Country | Link |
---|---|
US (1) | US7049060B2 (de) |
EP (3) | EP2186884A3 (de) |
JP (1) | JP2004035534A (de) |
AT (2) | ATE382683T1 (de) |
CA (1) | CA2406240C (de) |
DE (2) | DE60235588D1 (de) |
DK (2) | DK1881064T3 (de) |
ES (2) | ES2339709T3 (de) |
PT (2) | PT1308507E (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8658773B2 (en) | 2011-05-02 | 2014-02-25 | Immunomedics, Inc. | Ultrafiltration concentration of allotype selected antibodies for small-volume administration |
US7902338B2 (en) | 2003-07-31 | 2011-03-08 | Immunomedics, Inc. | Anti-CD19 antibodies |
JP2009018990A (ja) * | 2005-10-25 | 2009-01-29 | Univ Kurume | C型肝炎ウイルス由来ペプチド |
US7858752B2 (en) * | 2006-12-05 | 2010-12-28 | Abbott Laboratories | Recombinant antibodies against hepatitis C virus and methods of obtaining and using same |
EP3243527B1 (de) | 2009-02-13 | 2019-06-05 | Immunomedics, Inc. | Immunkonjugate mit einem intrazellulär spaltbaren linker |
CA2774260C (en) | 2009-09-16 | 2018-10-09 | Immunomedics, Inc. | Class i anti-cea antibodies and uses thereof |
EP2506881B1 (de) | 2009-12-02 | 2024-03-06 | Immunomedics, Inc. | Kombination aus radioimmuntherapie und antikörper-arznei-konjugaten für verbesserte krebstherapie |
WO2012006500A2 (en) * | 2010-07-08 | 2012-01-12 | Abbott Laboratories | Monoclonal antibodies against hepatitis c virus core protein |
FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
US9315567B2 (en) | 2012-08-14 | 2016-04-19 | Ibc Pharmaceuticals, Inc. | T-cell redirecting bispecific antibodies for treatment of disease |
HRP20220399T1 (hr) | 2012-12-13 | 2022-05-13 | Immunomedics, Inc. | Režim doziranja imunokonjugata protutijela i sn-38 za poboljšanu učinkovitost i smanjenu toksičnost |
JP6739329B2 (ja) | 2013-03-14 | 2020-08-12 | アボット・ラボラトリーズAbbott Laboratories | Hcvコア脂質結合ドメインモノクローナル抗体 |
EP2968526A4 (de) | 2013-03-14 | 2016-11-09 | Abbott Lab | Hcv-antigen-antikörper-kombinationstest sowie verfahren und zusammensetzungen zur verwendung darin |
JP2016512241A (ja) | 2013-03-14 | 2016-04-25 | アボット・ラボラトリーズAbbott Laboratories | 改良された抗体検出のためのhcvns3組換え抗原およびこの突然変異体 |
MX2016010683A (es) | 2014-02-21 | 2017-05-11 | Ibc Pharmaceuticals Inc | Terapia para tratar enfermedades mediante la induccion de respuesta inmune de las células que expresan trop-2. |
CN106029098A (zh) | 2014-02-25 | 2016-10-12 | 免疫医疗公司 | 人源化rfb4抗cd22抗体 |
US9580495B2 (en) | 2014-06-24 | 2017-02-28 | Immunomedics, Inc. | Anti-histone therapy for vascular necrosis in severe glomerulonephritis |
CN106999517A (zh) | 2014-10-07 | 2017-08-01 | 免疫医疗公司 | 抗体‑药物缀合物的新辅助剂用途 |
EP3286224A4 (de) | 2015-04-22 | 2018-11-14 | Immunomedics, Inc. | Isolierung, detektion, diagnose und/oder charakterisierung von zirkulierenden trop-2-positiven krebszellen |
WO2016210108A1 (en) | 2015-06-25 | 2016-12-29 | Immunomedics, Inc. | Combining anti-hla-dr or anti-trop-2 antibodies with microtubule inhibitors, parp inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer |
SI3316885T1 (sl) | 2015-07-01 | 2021-09-30 | Immunomedics, Inc. | Imunokonjugati protitelo-SN-38 z linkerjem CL2A |
WO2017207599A1 (en) | 2016-05-31 | 2017-12-07 | Roche Diagnostics Gmbh | Method for serological detection of viral antigens |
CN109154617B (zh) | 2016-05-31 | 2022-08-26 | 豪夫迈·罗氏有限公司 | 用于hcv核心抗原的快速检测的预处理方法 |
EP3577460B1 (de) | 2017-02-02 | 2021-01-20 | Roche Diagnostics GmbH | Immunoassay mit mindestens zwei pegylierten analyt-spezifischen bindungsmitteln |
ES2961462T3 (es) | 2017-07-27 | 2024-03-12 | Roche Diagnostics Gmbh | Proteína de fusión multiepítopo de un antígeno del VHC y usos de la misma |
CN109738648B (zh) * | 2018-12-29 | 2021-09-17 | 山东莱博生物科技有限公司 | 稳定高效表达丙型肝炎病毒核心抗原抗体的工程细胞株及其应用 |
EP4342497A1 (de) | 2021-05-10 | 2024-03-27 | Kawasaki Institute of Industrial Promotion | Antikörper mit reduzierter bindungsaffinität für antigen |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUT54896A (en) | 1989-03-17 | 1991-04-29 | Chiron Corp | Process for producing aquous diagnosticum and vaccine of nanbv |
DE4209215A1 (de) * | 1991-07-04 | 1993-01-07 | Boehringer Mannheim Gmbh | Hcv peptidantigene und verfahren zur bestimmung von hcv |
ZA927837B (en) | 1991-10-15 | 1994-03-11 | Akzo Nv | Monoclonal antibodiesto hepatitis C virus |
JP3217600B2 (ja) * | 1994-07-12 | 2001-10-09 | 株式会社先端生命科学研究所 | 非a非b型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ |
FR2775690B1 (fr) | 1998-03-09 | 2001-12-14 | Bio Merieux | Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc |
WO2000063444A2 (en) | 1999-04-14 | 2000-10-26 | Institut Pasteur | Method for detecting hepatitis c virus with hybridomas |
CN100463922C (zh) * | 2000-06-15 | 2009-02-25 | 诺华疫苗和诊断公司 | 抗hcv抗体的免疫测定 |
CA2450710C (en) * | 2001-06-26 | 2013-11-26 | Abbott Laboratories | Methods for the simultaneous detection of hcv antigens and hcv antibodies |
-
2002
- 2002-10-10 US US10/268,561 patent/US7049060B2/en not_active Expired - Lifetime
- 2002-11-04 DE DE60235588T patent/DE60235588D1/de not_active Expired - Lifetime
- 2002-11-04 AT AT02257622T patent/ATE382683T1/de active
- 2002-11-04 EP EP10002088A patent/EP2186884A3/de not_active Withdrawn
- 2002-11-04 EP EP02257622A patent/EP1308507B1/de not_active Expired - Lifetime
- 2002-11-04 ES ES07075928T patent/ES2339709T3/es not_active Expired - Lifetime
- 2002-11-04 AT AT07075928T patent/ATE459706T1/de active
- 2002-11-04 PT PT02257622T patent/PT1308507E/pt unknown
- 2002-11-04 EP EP07075928A patent/EP1881064B1/de not_active Expired - Lifetime
- 2002-11-04 PT PT07075928T patent/PT1881064E/pt unknown
- 2002-11-04 DK DK07075928.7T patent/DK1881064T3/da active
- 2002-11-04 DK DK02257622T patent/DK1308507T3/da active
- 2002-11-04 DE DE60224346T patent/DE60224346T2/de not_active Expired - Lifetime
- 2002-11-04 ES ES02257622T patent/ES2295292T3/es not_active Expired - Lifetime
- 2002-11-05 JP JP2002321058A patent/JP2004035534A/ja active Pending
- 2002-11-05 CA CA2406240A patent/CA2406240C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US7049060B2 (en) | 2006-05-23 |
EP1881064B1 (de) | 2010-03-03 |
PT1308507E (pt) | 2008-03-31 |
EP2186884A3 (de) | 2010-09-08 |
ES2295292T3 (es) | 2008-04-16 |
DE60224346T2 (de) | 2008-12-24 |
EP1308507A3 (de) | 2003-10-22 |
PT1881064E (pt) | 2010-03-31 |
ATE459706T1 (de) | 2010-03-15 |
EP1308507B1 (de) | 2008-01-02 |
DK1308507T3 (da) | 2008-05-19 |
EP1881064A2 (de) | 2008-01-23 |
EP1881064A3 (de) | 2008-04-09 |
ES2339709T3 (es) | 2010-05-24 |
JP2004035534A (ja) | 2004-02-05 |
EP2186884A2 (de) | 2010-05-19 |
CA2406240C (en) | 2011-01-04 |
US20030148333A1 (en) | 2003-08-07 |
DE60235588D1 (de) | 2010-04-15 |
EP1308507A2 (de) | 2003-05-07 |
DK1881064T3 (da) | 2010-06-07 |
CA2406240A1 (en) | 2003-05-05 |
DE60224346D1 (de) | 2008-02-14 |
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