ATE382683T1 - Monoklonales antikörper gegen das hcv kernantigen - Google Patents

Monoklonales antikörper gegen das hcv kernantigen

Info

Publication number
ATE382683T1
ATE382683T1 AT02257622T AT02257622T ATE382683T1 AT E382683 T1 ATE382683 T1 AT E382683T1 AT 02257622 T AT02257622 T AT 02257622T AT 02257622 T AT02257622 T AT 02257622T AT E382683 T1 ATE382683 T1 AT E382683T1
Authority
AT
Austria
Prior art keywords
core antigen
hcv core
monoclonal antibody
antibody against
antibodies
Prior art date
Application number
AT02257622T
Other languages
English (en)
Inventor
Chander Bahl
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Application granted granted Critical
Publication of ATE382683T1 publication Critical patent/ATE382683T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109Hepatitis C virus; Hepatitis G virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
AT02257622T 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen ATE382683T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33745301P 2001-11-05 2001-11-05
US10/268,561 US7049060B2 (en) 2001-11-05 2002-10-10 HCV anti-core monoclonal antibodies

Publications (1)

Publication Number Publication Date
ATE382683T1 true ATE382683T1 (de) 2008-01-15

Family

ID=26953173

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02257622T ATE382683T1 (de) 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen
AT07075928T ATE459706T1 (de) 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT07075928T ATE459706T1 (de) 2001-11-05 2002-11-04 Monoklonales antikörper gegen das hcv kernantigen

Country Status (9)

Country Link
US (1) US7049060B2 (de)
EP (3) EP2186884A3 (de)
JP (1) JP2004035534A (de)
AT (2) ATE382683T1 (de)
CA (1) CA2406240C (de)
DE (2) DE60235588D1 (de)
DK (2) DK1881064T3 (de)
ES (2) ES2339709T3 (de)
PT (2) PT1308507E (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8658773B2 (en) 2011-05-02 2014-02-25 Immunomedics, Inc. Ultrafiltration concentration of allotype selected antibodies for small-volume administration
US7902338B2 (en) 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
JP2009018990A (ja) * 2005-10-25 2009-01-29 Univ Kurume C型肝炎ウイルス由来ペプチド
US7858752B2 (en) * 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
EP3243527B1 (de) 2009-02-13 2019-06-05 Immunomedics, Inc. Immunkonjugate mit einem intrazellulär spaltbaren linker
CA2774260C (en) 2009-09-16 2018-10-09 Immunomedics, Inc. Class i anti-cea antibodies and uses thereof
EP2506881B1 (de) 2009-12-02 2024-03-06 Immunomedics, Inc. Kombination aus radioimmuntherapie und antikörper-arznei-konjugaten für verbesserte krebstherapie
WO2012006500A2 (en) * 2010-07-08 2012-01-12 Abbott Laboratories Monoclonal antibodies against hepatitis c virus core protein
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
US9315567B2 (en) 2012-08-14 2016-04-19 Ibc Pharmaceuticals, Inc. T-cell redirecting bispecific antibodies for treatment of disease
HRP20220399T1 (hr) 2012-12-13 2022-05-13 Immunomedics, Inc. Režim doziranja imunokonjugata protutijela i sn-38 za poboljšanu učinkovitost i smanjenu toksičnost
JP6739329B2 (ja) 2013-03-14 2020-08-12 アボット・ラボラトリーズAbbott Laboratories Hcvコア脂質結合ドメインモノクローナル抗体
EP2968526A4 (de) 2013-03-14 2016-11-09 Abbott Lab Hcv-antigen-antikörper-kombinationstest sowie verfahren und zusammensetzungen zur verwendung darin
JP2016512241A (ja) 2013-03-14 2016-04-25 アボット・ラボラトリーズAbbott Laboratories 改良された抗体検出のためのhcvns3組換え抗原およびこの突然変異体
MX2016010683A (es) 2014-02-21 2017-05-11 Ibc Pharmaceuticals Inc Terapia para tratar enfermedades mediante la induccion de respuesta inmune de las células que expresan trop-2.
CN106029098A (zh) 2014-02-25 2016-10-12 免疫医疗公司 人源化rfb4抗cd22抗体
US9580495B2 (en) 2014-06-24 2017-02-28 Immunomedics, Inc. Anti-histone therapy for vascular necrosis in severe glomerulonephritis
CN106999517A (zh) 2014-10-07 2017-08-01 免疫医疗公司 抗体‑药物缀合物的新辅助剂用途
EP3286224A4 (de) 2015-04-22 2018-11-14 Immunomedics, Inc. Isolierung, detektion, diagnose und/oder charakterisierung von zirkulierenden trop-2-positiven krebszellen
WO2016210108A1 (en) 2015-06-25 2016-12-29 Immunomedics, Inc. Combining anti-hla-dr or anti-trop-2 antibodies with microtubule inhibitors, parp inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
SI3316885T1 (sl) 2015-07-01 2021-09-30 Immunomedics, Inc. Imunokonjugati protitelo-SN-38 z linkerjem CL2A
WO2017207599A1 (en) 2016-05-31 2017-12-07 Roche Diagnostics Gmbh Method for serological detection of viral antigens
CN109154617B (zh) 2016-05-31 2022-08-26 豪夫迈·罗氏有限公司 用于hcv核心抗原的快速检测的预处理方法
EP3577460B1 (de) 2017-02-02 2021-01-20 Roche Diagnostics GmbH Immunoassay mit mindestens zwei pegylierten analyt-spezifischen bindungsmitteln
ES2961462T3 (es) 2017-07-27 2024-03-12 Roche Diagnostics Gmbh Proteína de fusión multiepítopo de un antígeno del VHC y usos de la misma
CN109738648B (zh) * 2018-12-29 2021-09-17 山东莱博生物科技有限公司 稳定高效表达丙型肝炎病毒核心抗原抗体的工程细胞株及其应用
EP4342497A1 (de) 2021-05-10 2024-03-27 Kawasaki Institute of Industrial Promotion Antikörper mit reduzierter bindungsaffinität für antigen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT54896A (en) 1989-03-17 1991-04-29 Chiron Corp Process for producing aquous diagnosticum and vaccine of nanbv
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
ZA927837B (en) 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非a非b型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
FR2775690B1 (fr) 1998-03-09 2001-12-14 Bio Merieux Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc
WO2000063444A2 (en) 1999-04-14 2000-10-26 Institut Pasteur Method for detecting hepatitis c virus with hybridomas
CN100463922C (zh) * 2000-06-15 2009-02-25 诺华疫苗和诊断公司 抗hcv抗体的免疫测定
CA2450710C (en) * 2001-06-26 2013-11-26 Abbott Laboratories Methods for the simultaneous detection of hcv antigens and hcv antibodies

Also Published As

Publication number Publication date
US7049060B2 (en) 2006-05-23
EP1881064B1 (de) 2010-03-03
PT1308507E (pt) 2008-03-31
EP2186884A3 (de) 2010-09-08
ES2295292T3 (es) 2008-04-16
DE60224346T2 (de) 2008-12-24
EP1308507A3 (de) 2003-10-22
PT1881064E (pt) 2010-03-31
ATE459706T1 (de) 2010-03-15
EP1308507B1 (de) 2008-01-02
DK1308507T3 (da) 2008-05-19
EP1881064A2 (de) 2008-01-23
EP1881064A3 (de) 2008-04-09
ES2339709T3 (es) 2010-05-24
JP2004035534A (ja) 2004-02-05
EP2186884A2 (de) 2010-05-19
CA2406240C (en) 2011-01-04
US20030148333A1 (en) 2003-08-07
DE60235588D1 (de) 2010-04-15
EP1308507A2 (de) 2003-05-07
DK1881064T3 (da) 2010-06-07
CA2406240A1 (en) 2003-05-05
DE60224346D1 (de) 2008-02-14

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