ATE459706T1 - Monoklonales antikörper gegen das hcv kernantigen - Google Patents
Monoklonales antikörper gegen das hcv kernantigenInfo
- Publication number
- ATE459706T1 ATE459706T1 AT07075928T AT07075928T ATE459706T1 AT E459706 T1 ATE459706 T1 AT E459706T1 AT 07075928 T AT07075928 T AT 07075928T AT 07075928 T AT07075928 T AT 07075928T AT E459706 T1 ATE459706 T1 AT E459706T1
- Authority
- AT
- Austria
- Prior art keywords
- core antigen
- hcv core
- monoclonal antibody
- antibody against
- antibodies
- Prior art date
Links
- 101710132601 Capsid protein Proteins 0.000 title 1
- 108700039791 Hepatitis C virus nucleocapsid Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
- C07K16/109—Hepatitis C virus; Hepatitis G virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33745301P | 2001-11-05 | 2001-11-05 | |
| US10/268,561 US7049060B2 (en) | 2001-11-05 | 2002-10-10 | HCV anti-core monoclonal antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE459706T1 true ATE459706T1 (de) | 2010-03-15 |
Family
ID=26953173
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07075928T ATE459706T1 (de) | 2001-11-05 | 2002-11-04 | Monoklonales antikörper gegen das hcv kernantigen |
| AT02257622T ATE382683T1 (de) | 2001-11-05 | 2002-11-04 | Monoklonales antikörper gegen das hcv kernantigen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02257622T ATE382683T1 (de) | 2001-11-05 | 2002-11-04 | Monoklonales antikörper gegen das hcv kernantigen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7049060B2 (de) |
| EP (3) | EP1881064B1 (de) |
| JP (1) | JP2004035534A (de) |
| AT (2) | ATE459706T1 (de) |
| CA (1) | CA2406240C (de) |
| DE (2) | DE60235588D1 (de) |
| DK (2) | DK1881064T3 (de) |
| ES (2) | ES2339709T3 (de) |
| PT (2) | PT1308507E (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7902338B2 (en) | 2003-07-31 | 2011-03-08 | Immunomedics, Inc. | Anti-CD19 antibodies |
| JP2009018990A (ja) * | 2005-10-25 | 2009-01-29 | Univ Kurume | Ｃ型肝炎ウイルス由来ペプチド |
| US7858752B2 (en) | 2006-12-05 | 2010-12-28 | Abbott Laboratories | Recombinant antibodies against hepatitis C virus and methods of obtaining and using same |
| US20160095939A1 (en) | 2014-10-07 | 2016-04-07 | Immunomedics, Inc. | Neoadjuvant use of antibody-drug conjugates |
| PL3939617T3 (pl) | 2009-02-13 | 2025-03-17 | Immunomedics, Inc. | Związki pośrednie do wytwarzania koniugatów z wiązaniem rozszczepialnym wewnątrzkomórkowo |
| CN102482701B (zh) | 2009-09-16 | 2015-05-13 | 免疫医疗公司 | I类抗-cea抗体及其使用 |
| CA2782194C (en) | 2009-12-02 | 2018-01-16 | Immunomedics, Inc. | Combination of radiolabelled antibodies (rait) and antibody-drug conjugates (adc) for treatment of pancreatic cancer |
| WO2012006500A2 (en) * | 2010-07-08 | 2012-01-12 | Abbott Laboratories | Monoclonal antibodies against hepatitis c virus core protein |
| JP6024025B2 (ja) | 2011-05-02 | 2016-11-09 | イミューノメディクス、インコーポレイテッドＩｍｍｕｎｏｍｅｄｉｃｓ， Ｉｎｃ． | 少容量投与用のアロタイプ選択抗体の限外濾過濃縮 |
| FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
| WO2014028560A2 (en) | 2012-08-14 | 2014-02-20 | Ibc Pharmaceuticals, Inc. | T-cell redirecting bispecific antibodies for treatment of disease |
| BR112015013444B1 (pt) | 2012-12-13 | 2022-11-01 | Immunomedics, Inc | Uso de um imunoconjugado |
| JP2016512241A (ja) | 2013-03-14 | 2016-04-25 | アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ | 改良された抗体検出のためのｈｃｖｎｓ３組換え抗原およびこの突然変異体 |
| CA2906417C (en) | 2013-03-14 | 2022-06-21 | Robert Ziemann | Hcv core lipid binding domain monoclonal antibodies |
| CN105228649B (zh) | 2013-03-14 | 2019-01-18 | 雅培制药有限公司 | Hcv抗原-抗体组合测定和方法以及用在其中的组合物 |
| EP3107577B1 (de) | 2014-02-21 | 2024-03-20 | IBC Pharmaceuticals, Inc. | Krankheitstherapie durch induktion einer immunantwort gegen trop-2-exprimierende zellen |
| EP3110445A4 (de) | 2014-02-25 | 2017-09-27 | Immunomedics, Inc. | Humanisierter rfb4-anti-cd22-antikörper |
| EP3160504B1 (de) | 2014-06-24 | 2020-09-16 | Immunomedics, Inc. | Antihistontherapie für vaskuläre nekrose bei schwerer glomerulonephritis |
| EP3286224A4 (de) | 2015-04-22 | 2018-11-14 | Immunomedics, Inc. | Isolierung, detektion, diagnose und/oder charakterisierung von zirkulierenden trop-2-positiven krebszellen |
| CN107735104B (zh) | 2015-06-25 | 2022-05-03 | 免疫医疗公司 | 组合抗hla-dr抗体或抗trop-2抗体与微管抑制剂、parp抑制剂、布鲁顿激酶抑制剂或磷酸肌醇3-激酶抑制剂使癌症治疗结果显著改善 |
| EP3316885B1 (de) | 2015-07-01 | 2021-06-23 | Immunomedics, Inc. | Antikörper-sn-38-immunkonjugate mit einem cl2a-linker |
| CN109154616B (zh) | 2016-05-31 | 2022-07-12 | 豪夫迈·罗氏有限公司 | 用于病毒抗原的血清学检测的方法 |
| KR102156994B1 (ko) | 2016-05-31 | 2020-09-17 | 에프. 호프만-라 로슈 아게 | Hcv 코어 항원의 신속한 검출을 위한 전처리 방법 |
| CN110234995A (zh) | 2017-02-02 | 2019-09-13 | 豪夫迈·罗氏有限公司 | 使用至少两种聚乙二醇化的分析物特异性结合试剂的免疫测定 |
| EP3658171B1 (de) | 2017-07-27 | 2023-08-30 | Roche Diagnostics GmbH | Multi-epitop-fusionsprotein eines hcv-antigens und verwendungen davon |
| CN109738648B (zh) * | 2018-12-29 | 2021-09-17 | 山东莱博生物科技有限公司 | 稳定高效表达丙型肝炎病毒核心抗原抗体的工程细胞株及其应用 |
| WO2022239720A1 (ja) | 2021-05-10 | 2022-11-17 | 公益財団法人川崎市産業振興財団 | 抗原への結合親和性を低減させた抗体 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990011089A1 (en) | 1989-03-17 | 1990-10-04 | Chiron Corporation | Nanbv diagnostics and vaccines |
| DE4209215A1 (de) * | 1991-07-04 | 1993-01-07 | Boehringer Mannheim Gmbh | Hcv peptidantigene und verfahren zur bestimmung von hcv |
| ZA927837B (en) | 1991-10-15 | 1994-03-11 | Akzo Nv | Monoclonal antibodiesto hepatitis C virus |
| JP3217600B2 (ja) * | 1994-07-12 | 2001-10-09 | 株式会社先端生命科学研究所 | 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ |
| FR2775690B1 (fr) | 1998-03-09 | 2001-12-14 | Bio Merieux | Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc |
| WO2000063444A2 (en) | 1999-04-14 | 2000-10-26 | Institut Pasteur | Method for detecting hepatitis c virus with hybridomas |
| ES2288969T3 (es) * | 2000-06-15 | 2008-02-01 | Novartis Vaccines And Diagnostics, Inc. | Inmunoensayos para anticuerpos anti-hcv. |
| CA2450710C (en) * | 2001-06-26 | 2013-11-26 | Abbott Laboratories | Methods for the simultaneous detection of hcv antigens and hcv antibodies |
-
2002
- 2002-10-10 US US10/268,561 patent/US7049060B2/en not_active Expired - Lifetime
- 2002-11-04 AT AT07075928T patent/ATE459706T1/de active
- 2002-11-04 DE DE60235588T patent/DE60235588D1/de not_active Expired - Lifetime
- 2002-11-04 EP EP07075928A patent/EP1881064B1/de not_active Expired - Lifetime
- 2002-11-04 DK DK07075928.7T patent/DK1881064T3/da active
- 2002-11-04 ES ES07075928T patent/ES2339709T3/es not_active Expired - Lifetime
- 2002-11-04 DK DK02257622T patent/DK1308507T3/da active
- 2002-11-04 DE DE60224346T patent/DE60224346T2/de not_active Expired - Lifetime
- 2002-11-04 EP EP10002088A patent/EP2186884A3/de not_active Withdrawn
- 2002-11-04 PT PT02257622T patent/PT1308507E/pt unknown
- 2002-11-04 ES ES02257622T patent/ES2295292T3/es not_active Expired - Lifetime
- 2002-11-04 PT PT07075928T patent/PT1881064E/pt unknown
- 2002-11-04 EP EP02257622A patent/EP1308507B1/de not_active Expired - Lifetime
- 2002-11-04 AT AT02257622T patent/ATE382683T1/de active
- 2002-11-05 JP JP2002321058A patent/JP2004035534A/ja active Pending
- 2002-11-05 CA CA2406240A patent/CA2406240C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK1881064T3 (da) | 2010-06-07 |
| US7049060B2 (en) | 2006-05-23 |
| ATE382683T1 (de) | 2008-01-15 |
| EP2186884A3 (de) | 2010-09-08 |
| US20030148333A1 (en) | 2003-08-07 |
| EP2186884A2 (de) | 2010-05-19 |
| CA2406240C (en) | 2011-01-04 |
| PT1308507E (pt) | 2008-03-31 |
| CA2406240A1 (en) | 2003-05-05 |
| DE60224346D1 (de) | 2008-02-14 |
| EP1308507A3 (de) | 2003-10-22 |
| EP1881064B1 (de) | 2010-03-03 |
| DK1308507T3 (da) | 2008-05-19 |
| ES2295292T3 (es) | 2008-04-16 |
| DE60235588D1 (de) | 2010-04-15 |
| EP1308507B1 (de) | 2008-01-02 |
| JP2004035534A (ja) | 2004-02-05 |
| PT1881064E (pt) | 2010-03-31 |
| ES2339709T3 (es) | 2010-05-24 |
| EP1881064A2 (de) | 2008-01-23 |
| EP1881064A3 (de) | 2008-04-09 |
| EP1308507A2 (de) | 2003-05-07 |
| DE60224346T2 (de) | 2008-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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