ATE452147T1 - Antikörper mit korrigierten cdr - Google Patents

Antikörper mit korrigierten cdr

Info

Publication number
ATE452147T1
ATE452147T1 AT05723312T AT05723312T ATE452147T1 AT E452147 T1 ATE452147 T1 AT E452147T1 AT 05723312 T AT05723312 T AT 05723312T AT 05723312 T AT05723312 T AT 05723312T AT E452147 T1 ATE452147 T1 AT E452147T1
Authority
AT
Austria
Prior art keywords
antibodies
cdr
corrected
selection
present application
Prior art date
Application number
AT05723312T
Other languages
English (en)
Inventor
Mark S Dennis
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34886204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE452147(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE452147T1 publication Critical patent/ATE452147T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
AT05723312T 2004-02-19 2005-02-18 Antikörper mit korrigierten cdr ATE452147T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54584004P 2004-02-19 2004-02-19
PCT/US2005/005270 WO2005080432A2 (en) 2004-02-19 2005-02-18 Cdr-repaired antibodies

Publications (1)

Publication Number Publication Date
ATE452147T1 true ATE452147T1 (de) 2010-01-15

Family

ID=34886204

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05723312T ATE452147T1 (de) 2004-02-19 2005-02-18 Antikörper mit korrigierten cdr

Country Status (9)

Country Link
US (2) US20060122377A1 (de)
EP (3) EP2168986A3 (de)
AT (1) ATE452147T1 (de)
AU (1) AU2005214382B2 (de)
CA (1) CA2555820C (de)
DE (1) DE602005018325D1 (de)
DK (1) DK1716181T3 (de)
ES (1) ES2337473T3 (de)
WO (1) WO2005080432A2 (de)

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CN104507969A (zh) 2012-07-19 2015-04-08 阿莱斯亚生物疗法股份有限公司 抗siglec-15抗体
MX362456B (es) 2012-08-24 2019-01-18 Univ California Anticuerpos y vacunas para utilizarse en el tratamiento de canceres por ror1 y para inhibir la metastasis.
PL220297B1 (pl) * 2012-11-07 2015-10-30 Wrocławskie Ct Badań Eit & Spółka Z Ograniczoną Odpowiedzialności& Epitop i jego zastosowanie
CN108424453B (zh) 2012-11-09 2021-08-06 基因先端领域株式会社 用于治疗癌症的抗adam28抗体
WO2014123186A1 (ja) 2013-02-06 2014-08-14 公立大学法人横浜市立大学 抗セマフォリン３ａ抗体、並びにこれを用いたアルツハイマー病及び免疫・炎症性疾患の治療
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CN117157401A (zh) 2021-04-05 2023-12-01 公立大学法人大阪 针对胰腺癌干细胞的抗体

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Also Published As

Publication number Publication date
EP1716181B1 (de) 2009-12-16
WO2005080432A3 (en) 2006-02-16
AU2005214382B2 (en) 2011-08-04
US20060122377A1 (en) 2006-06-08
AU2005214382A1 (en) 2005-09-01
EP3653641A1 (de) 2020-05-20
EP2168986A3 (de) 2010-07-28
US8580928B2 (en) 2013-11-12
ES2337473T3 (es) 2010-04-26
EP2168986A2 (de) 2010-03-31
DE602005018325D1 (de) 2010-01-28
CA2555820A1 (en) 2005-09-01
DK1716181T3 (da) 2010-03-01
CA2555820C (en) 2016-01-19
US20110237779A1 (en) 2011-09-29
WO2005080432A2 (en) 2005-09-01
EP1716181A2 (de) 2006-11-02

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