DK1787126T3 - Fremgangsmåde til karakterisering af en polyklonal cellelinie - Google Patents
Fremgangsmåde til karakterisering af en polyklonal cellelinieInfo
- Publication number
- DK1787126T3 DK1787126T3 DK05760790T DK05760790T DK1787126T3 DK 1787126 T3 DK1787126 T3 DK 1787126T3 DK 05760790 T DK05760790 T DK 05760790T DK 05760790 T DK05760790 T DK 05760790T DK 1787126 T3 DK1787126 T3 DK 1787126T3
- Authority
- DK
- Denmark
- Prior art keywords
- cell line
- polyclonal
- platform
- polyclonal cell
- characterizing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Document Processing Apparatus (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200401133 | 2004-07-20 | ||
| DKPA200401991 | 2004-12-22 | ||
| PCT/DK2005/000504 WO2006007853A2 (en) | 2004-07-20 | 2005-07-20 | A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1787126T3 true DK1787126T3 (da) | 2009-12-21 |
Family
ID=35427551
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05760790T DK1787126T3 (da) | 2004-07-20 | 2005-07-20 | Fremgangsmåde til karakterisering af en polyklonal cellelinie |
| DK09151073.5T DK2053408T3 (da) | 2004-07-20 | 2005-07-20 | Fremgangsmåde til strukturel karakterisering af et rekombinant polyklonalt protein eller en polyklonal cellelinje |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09151073.5T DK2053408T3 (da) | 2004-07-20 | 2005-07-20 | Fremgangsmåde til strukturel karakterisering af et rekombinant polyklonalt protein eller en polyklonal cellelinje |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8288109B2 (da) |
| EP (2) | EP1787126B1 (da) |
| JP (1) | JP4870667B2 (da) |
| KR (1) | KR101319848B1 (da) |
| AT (2) | ATE443870T1 (da) |
| AU (1) | AU2005263334C1 (da) |
| BR (1) | BRPI0513714A (da) |
| CA (1) | CA2574146C (da) |
| DE (1) | DE602005016818D1 (da) |
| DK (2) | DK1787126T3 (da) |
| ES (2) | ES2381531T3 (da) |
| HK (2) | HK1101043A1 (da) |
| IL (2) | IL180169A (da) |
| MX (1) | MX2007000551A (da) |
| NO (1) | NO20070931L (da) |
| NZ (1) | NZ552264A (da) |
| PL (2) | PL1787126T3 (da) |
| RU (1) | RU2426795C2 (da) |
| WO (1) | WO2006007853A2 (da) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1583830T1 (sl) | 2003-01-07 | 2006-12-31 | Symphogen As | Postopek za pripravo rekombinantnih poliklonskih proteinov |
| TWI333977B (en) | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| EA014182B1 (ru) | 2004-07-20 | 2010-10-29 | Симфоген А/С | КОМПОЗИЦИЯ ПОЛИКЛОНАЛЬНЫХ АНТИ-RhD АНТИТЕЛ, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ КОМПОЗИЦИИ |
| PL1787126T3 (pl) | 2004-07-20 | 2010-03-31 | Symphogen As | Sposób charakteryzowania poliklonalnej linii komórkowej |
| AU2006322445B2 (en) | 2005-12-05 | 2011-05-12 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
| US8338376B2 (en) | 2006-10-20 | 2012-12-25 | Biogen Idec Ma Inc. | Compositions comprising variant LT-B-R-IG fusion proteins |
| WO2008104183A2 (en) * | 2007-03-01 | 2008-09-04 | Symphogen A/S | Recombinant anti-epidermal growth factor receptor antibody compositions |
| EP2121920B1 (en) | 2007-03-01 | 2011-08-24 | Symphogen A/S | Method for cloning cognate antibodies |
| JP2010534057A (ja) | 2007-03-06 | 2010-11-04 | シムフォゲン・アクティーゼルスカブ | 呼吸器合胞体ウイルス感染症を治療するための組換え抗体 |
| CA2680792A1 (en) * | 2007-03-15 | 2008-09-18 | Biogen Idec Ma Inc. | Treatment of autoimmune disorders |
| SI2152872T1 (sl) | 2007-05-25 | 2011-01-31 | Symphogen As | Postopek za pripravo rekombinantnega poliklonskega proteina |
| JP2008289483A (ja) * | 2007-05-25 | 2008-12-04 | Symphogen As | 真核生物系において発現可能な形質転換体のスクリーニング |
| MX2010002044A (es) * | 2007-09-07 | 2010-03-18 | Symphogen As | Metodos para produccion recombinante de anticuerpos anti-virus sincitial respiratorio (anti-rsv). |
| MX2010005377A (es) * | 2007-11-22 | 2010-06-25 | Symphogen As | Metodo para caracterizacion de proteina policlonal recombinante. |
| CN102007146A (zh) * | 2008-04-23 | 2011-04-06 | 西福根有限公司 | 用于制备多克隆蛋白质的方法 |
| BRPI0917352A2 (pt) * | 2008-08-29 | 2017-08-22 | Symphogen As | Métodos para produção de uma biblioteca de pares cognatos que compreende sequências ligadas que codificam regiões variáveis e para gerar um vetor que codifica um anticorpo quimérico com regiões de seres humanos constantes e regiões variáveis não humanas, biblioteca de vetores, e método para produção de uma biblioteca de sequências de imunoglobulina derivadas de aves |
| AU2009287163B2 (en) | 2008-08-29 | 2014-11-13 | Les Laboratoires Servier | Recombinant anti-Epidermal Growth Factor Receptor antibody compositions |
| US8821879B2 (en) | 2009-09-04 | 2014-09-02 | Xoma Technology Ltd. | Anti-botulism antibody coformulations |
| US20120264155A1 (en) * | 2009-10-09 | 2012-10-18 | Symphogen A/S | Multiplex Quantitation of Individual Recombinant Proteins in a Mixture by Signature Peptides and Mass Spectrometry |
| MX360403B (es) * | 2010-04-15 | 2018-10-31 | Abbvie Inc | Proteinas de union a amiloide beta. |
| JP6186277B2 (ja) | 2010-11-01 | 2017-08-23 | シムフォゲン・アクティーゼルスカブＳｙｍｐｈｏｇｅｎ Ａ／Ｓ | 抗ｈｅｒ３抗体および組成物 |
| EP2953970A4 (en) | 2013-02-08 | 2016-06-29 | Misfolding Diagnostics Inc | TRANSTYRETIN ANTIBODIES AND USES THEREOF |
| UY35517A (es) | 2013-04-04 | 2014-10-31 | Mabxience S A | Un procedimiento para aumentar la formación de ácido piroglutamico de una proteína |
| WO2015093925A1 (es) * | 2013-12-19 | 2015-06-25 | CASTRO ALDRETE, Jorge Isaac | Método de producción de anticuerpos específicos |
| TW201623331A (zh) * | 2014-03-12 | 2016-07-01 | 普羅帝納生物科學公司 | 抗黑色素瘤細胞黏著分子（ｍｃａｍ）抗體類及使用彼等之相關方法 |
| US11680948B2 (en) | 2016-08-12 | 2023-06-20 | Abreos Biosciences, Inc. | Detection and quantification of natalizumab |
| WO2019243626A1 (en) * | 2018-06-22 | 2019-12-26 | Genmab A/S | Method for producing a controlled mixture of two or more different antibodies |
| CN112816595A (zh) * | 2021-01-06 | 2021-05-18 | 海默斯（重庆）医学生物技术有限公司 | 一种重组角蛋白液体制剂及其纯度检测方法 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0162918A1 (en) | 1983-11-28 | 1985-12-04 | The Board Of Trustees Of The Leland Stanford Junior University | HUMAN MONOCLONAL ANTIBODY AGAINST Rh(D) ANTIGEN AND ITS USES |
| IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
| CA1293460C (en) | 1985-10-07 | 1991-12-24 | Brian Lee Sauer | Site-specific recombination of dna in yeast |
| US5126130A (en) | 1986-11-24 | 1992-06-30 | The Childrens Hospital Incorporated | Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein a |
| GB8722018D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| GB8722020D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| GB8722019D0 (en) | 1987-09-18 | 1987-10-28 | Central Blood Lab Authority | Human anti-rh(d)monoclonal antibodies |
| AU634186B2 (en) | 1988-11-11 | 1993-02-18 | Medical Research Council | Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors |
| GB8906129D0 (en) | 1989-03-17 | 1989-05-04 | Central Blood Lab Authority | Pharmaceutical preparations |
| GB8919761D0 (en) | 1989-09-01 | 1989-10-18 | Central Blood Lab Authority | Chemical compounds |
| WO1992015694A1 (en) | 1991-03-08 | 1992-09-17 | The Salk Institute For Biological Studies | Flp-mediated gene modification in mammalian cells, and compositions and cells useful therefor |
| US5837268A (en) * | 1991-10-16 | 1998-11-17 | University Of Saskatchewan | GnRH-leukotoxin chimeras |
| US5252216A (en) * | 1992-03-24 | 1993-10-12 | Smithkline Beecham Corporation | Protein purification |
| DE69328135D1 (de) | 1992-06-26 | 2000-04-27 | Aetsrn | Menschliche monoklonale Antikörper gegen Rhesus D und Zellinien die diese produzieren |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| ATE243745T1 (de) | 1994-01-31 | 2003-07-15 | Univ Boston | Bibliotheken aus polyklonalen antikörpern |
| FR2724182B1 (fr) | 1994-09-02 | 1996-12-13 | Pasteur Institut | Obtention d'un anticorps monoclonal recombinant a partir d'un anticorps monoclonal humain anti-rhesus d, sa production en cellules d'insecte, et ses utilisations |
| US6111166A (en) | 1994-09-19 | 2000-08-29 | Medarex, Incorporated | Transgenic mice expressing human Fcα and β receptors |
| JP3841360B2 (ja) | 1996-06-24 | 2006-11-01 | ツェットエルベー・ベリング・アクチェンゲゼルシャフト | リーサスｄ抗原に対して特異性を有する抗原結合性構造を形成し得るポリペプチド、それらをコードするｄｎａ及びその調製方法並びに使用 |
| US5876925A (en) | 1996-10-11 | 1999-03-02 | The Trustees Of The University Of Pennsylvania | Magnetically activated cell sorting for production of proteins |
| US6255455B1 (en) | 1996-10-11 | 2001-07-03 | The Trustees Of The University Of Pennsylvania | Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof |
| RO120148B1 (ro) | 1997-03-14 | 2005-09-30 | Idec Pharmaceuticals Corporation | Sistem vector şi procedeu de inserţie a unui fragment adn, în genomul celulelor de mamifere |
| JPH11174038A (ja) * | 1997-12-10 | 1999-07-02 | Tosoh Corp | 蛋白質の分離精製法 |
| WO2000011155A1 (en) | 1998-08-19 | 2000-03-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for genomic modification |
| US20020155114A1 (en) * | 1998-08-31 | 2002-10-24 | James D. Marks | Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins |
| US6395538B1 (en) * | 1999-07-16 | 2002-05-28 | Human Genome Sciences, Inc. | Method and system for providing real-time, in situ biomanufacturing process monitoring and control in response to IR spectroscopy |
| ATE463569T1 (de) | 1999-07-23 | 2010-04-15 | Univ California | Dna-rekombination in eukaryotischen zellen mittels des rekombinationszentrums vom bakteriophag phic31 |
| EP1106625A1 (en) | 1999-11-17 | 2001-06-13 | ZLB Bioplasma AG | Rhesus D specific peptide sequences |
| WO2001058925A2 (en) | 2000-02-08 | 2001-08-16 | The Regents Of The University Of Michigan | Protein separation and display |
| JP2003534533A (ja) | 2000-02-08 | 2003-11-18 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | タンパク質のディファレンシャルディスプレイのマッピング |
| EP1385869A2 (en) | 2000-02-08 | 2004-02-04 | The Regents Of The University Of Michigan | Protein mapping |
| CA2410586C (en) | 2000-05-26 | 2010-07-20 | Symphogen A/S | Recombinant or purified polyclonal antibodies for treating allergy |
| US6610472B1 (en) | 2000-10-31 | 2003-08-26 | Genetastix Corporation | Assembly and screening of highly complex and fully human antibody repertoire in yeast |
| JP2004514444A (ja) * | 2000-11-28 | 2004-05-20 | アプライド モレキュラー エボリューション， インコーポレイテッド | 二重ｌｏｘ組換えに基づく真核生物発現ライブラリーおよび使用方法 |
| CA2433281C (en) | 2000-12-26 | 2011-02-22 | The Institute For Systems Biology | Rapid and quantitative proteome analysis and related methods |
| AU2002367582A1 (en) * | 2001-07-17 | 2003-09-29 | Ciphergen Biosystems, Inc. | Latex based adsorbent chip |
| DE60211744T3 (de) * | 2001-12-08 | 2010-07-01 | Micromass Uk Ltd. | Massenspektrometrie-verfahren |
| US20040033591A1 (en) | 2002-05-31 | 2004-02-19 | The Regents Of The University Of Michigan | Automated protein analysis system |
| JP4836451B2 (ja) | 2002-07-18 | 2011-12-14 | メルス ベー ヴェー | 抗体混合物の組換え生産 |
| JP2004101477A (ja) * | 2002-09-12 | 2004-04-02 | Yoshio Yamauchi | ２次元高速液体クロマトグラフ装置及びそれを用いた蛋白質分析装置 |
| AU2003284227A1 (en) | 2002-10-15 | 2004-05-04 | The Regents Of The University Of Michigan | Multidimensional protein separation system |
| SI1583830T1 (sl) | 2003-01-07 | 2006-12-31 | Symphogen As | Postopek za pripravo rekombinantnih poliklonskih proteinov |
| US20060275766A1 (en) * | 2003-01-07 | 2006-12-07 | Haurum John S | Method for manufacturing recombinant polyclonal proteins |
| TWI333977B (en) | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| PL1787126T3 (pl) | 2004-07-20 | 2010-03-31 | Symphogen As | Sposób charakteryzowania poliklonalnej linii komórkowej |
| EA014182B1 (ru) | 2004-07-20 | 2010-10-29 | Симфоген А/С | КОМПОЗИЦИЯ ПОЛИКЛОНАЛЬНЫХ АНТИ-RhD АНТИТЕЛ, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ КОМПОЗИЦИИ |
| AU2006322445B2 (en) | 2005-12-05 | 2011-05-12 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
| US20100040606A1 (en) | 2006-03-06 | 2010-02-18 | Symphogen A/S | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
| MX2010005377A (es) | 2007-11-22 | 2010-06-25 | Symphogen As | Metodo para caracterizacion de proteina policlonal recombinante. |
-
2005
- 2005-07-20 PL PL05760790T patent/PL1787126T3/pl unknown
- 2005-07-20 ES ES09151073T patent/ES2381531T3/es active Active
- 2005-07-20 BR BRPI0513714-4A patent/BRPI0513714A/pt not_active Application Discontinuation
- 2005-07-20 WO PCT/DK2005/000504 patent/WO2006007853A2/en active Application Filing
- 2005-07-20 AT AT05760790T patent/ATE443870T1/de active
- 2005-07-20 JP JP2007521795A patent/JP4870667B2/ja not_active Expired - Fee Related
- 2005-07-20 RU RU2007106050/10A patent/RU2426795C2/ru not_active IP Right Cessation
- 2005-07-20 MX MX2007000551A patent/MX2007000551A/es active IP Right Grant
- 2005-07-20 CA CA2574146A patent/CA2574146C/en not_active Expired - Fee Related
- 2005-07-20 DK DK05760790T patent/DK1787126T3/da active
- 2005-07-20 EP EP05760790A patent/EP1787126B1/en active Active
- 2005-07-20 PL PL09151073T patent/PL2053408T3/pl unknown
- 2005-07-20 DE DE602005016818T patent/DE602005016818D1/de active Active
- 2005-07-20 AT AT09151073T patent/ATE548657T1/de active
- 2005-07-20 AU AU2005263334A patent/AU2005263334C1/en not_active Ceased
- 2005-07-20 NZ NZ552264A patent/NZ552264A/en not_active IP Right Cessation
- 2005-07-20 US US11/658,021 patent/US8288109B2/en not_active Expired - Fee Related
- 2005-07-20 KR KR1020077003954A patent/KR101319848B1/ko not_active IP Right Cessation
- 2005-07-20 EP EP09151073A patent/EP2053408B1/en active Active
- 2005-07-20 ES ES05760790T patent/ES2332524T3/es active Active
- 2005-07-20 DK DK09151073.5T patent/DK2053408T3/da active
-
2006
- 2006-12-19 IL IL180169A patent/IL180169A/en not_active IP Right Cessation
-
2007
- 2007-02-19 NO NO20070931A patent/NO20070931L/no not_active Application Discontinuation
- 2007-06-07 HK HK07106079.4A patent/HK1101043A1/xx not_active IP Right Cessation
-
2009
- 2009-10-28 HK HK09109991.1A patent/HK1133076A1/xx not_active IP Right Cessation
- 2009-12-29 IL IL203017A patent/IL203017A/en not_active IP Right Cessation
-
2012
- 2012-10-16 US US13/653,316 patent/US9029091B2/en not_active Expired - Fee Related
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