ATE538217T1 - Erkennung von ektopischen schwangerschaften - Google Patents
Erkennung von ektopischen schwangerschaftenInfo
- Publication number
- ATE538217T1 ATE538217T1 AT08775831T AT08775831T ATE538217T1 AT E538217 T1 ATE538217 T1 AT E538217T1 AT 08775831 T AT08775831 T AT 08775831T AT 08775831 T AT08775831 T AT 08775831T AT E538217 T1 ATE538217 T1 AT E538217T1
- Authority
- AT
- Austria
- Prior art keywords
- activin
- identifying
- ectopic pregnancy
- ectopic
- cpb1
- Prior art date
Links
- 201000003511 ectopic pregnancy Diseases 0.000 title abstract 4
- 238000001514 detection method Methods 0.000 title 1
- 102100035024 Carboxypeptidase B Human genes 0.000 abstract 3
- 101710126281 Cysteine-rich secretory protein 3 Proteins 0.000 abstract 3
- 102100027367 Cysteine-rich secretory protein 3 Human genes 0.000 abstract 3
- 101000946524 Homo sapiens Carboxypeptidase B Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 101100179813 Drosophila melanogaster Actbeta gene Proteins 0.000 abstract 2
- 108010015972 Elafin Proteins 0.000 abstract 2
- 102100023795 Elafin Human genes 0.000 abstract 2
- 101000820585 Homo sapiens SUN domain-containing ossification factor Proteins 0.000 abstract 2
- 101000673946 Homo sapiens Synaptotagmin-like protein 1 Proteins 0.000 abstract 2
- 108010057464 Prolactin Proteins 0.000 abstract 2
- 102000003946 Prolactin Human genes 0.000 abstract 2
- 102100021651 SUN domain-containing ossification factor Human genes 0.000 abstract 2
- 108010023079 activin B Proteins 0.000 abstract 2
- MDCUNMLZLNGCQA-HWOAGHQOSA-N elafin Chemical compound N([C@H](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H]1C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]2CSSC[C@H]3C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CSSC[C@H]4C(=O)N5CCC[C@H]5C(=O)NCC(=O)N[C@H](C(N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H]5N(CCC5)C(=O)[C@H]5N(CCC5)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@H](C)NC2=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N4)C(=O)N[C@@H](CSSC1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N3)=O)[C@@H](C)CC)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(N)=O)C(O)=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)C(C)C)C(C)C)C(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)N MDCUNMLZLNGCQA-HWOAGHQOSA-N 0.000 abstract 2
- 239000000893 inhibin Substances 0.000 abstract 2
- ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 abstract 2
- 229940097325 prolactin Drugs 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000035935 pregnancy Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0712801A GB0712801D0 (en) | 2007-07-02 | 2007-07-02 | Identification of ectopic pregnancies |
| GB0805981A GB0805981D0 (en) | 2008-04-02 | 2008-04-02 | Identification of ectopic pregnancies |
| PCT/GB2008/002282 WO2009004340A2 (en) | 2007-07-02 | 2008-07-02 | Identification of ectopic pregnancies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE538217T1 true ATE538217T1 (de) | 2012-01-15 |
Family
ID=39811984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08775831T ATE538217T1 (de) | 2007-07-02 | 2008-07-02 | Erkennung von ektopischen schwangerschaften |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100285974A1 (de) |
| EP (1) | EP2171091B1 (de) |
| JP (1) | JP2010531991A (de) |
| AT (1) | ATE538217T1 (de) |
| WO (1) | WO2009004340A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8383351B2 (en) * | 2008-06-11 | 2013-02-26 | Oxford Brookes University | Antibody to inhibin/ activin β-B subunit |
| GB201203217D0 (en) * | 2012-02-23 | 2012-04-11 | King S College London | Marker for preterm labour |
| US20130237442A1 (en) * | 2012-03-07 | 2013-09-12 | University Of Miami | Methods and Compositions for Diagnosis of Non-Viable Early Pregnancy |
| CN106645736A (zh) * | 2016-06-16 | 2017-05-10 | 武汉兰卫医学检验所有限公司 | 一种异位妊娠、非孕蜕膜组织差异表达蛋白的筛选方法 |
| US12486535B2 (en) * | 2018-03-05 | 2025-12-02 | The Government Of The United States, As Represented By The Secretary Of The Army | Ectopic pregnancy kits and methods |
| CN112034180B (zh) * | 2020-08-18 | 2021-09-24 | 四川大学华西第二医院 | 角蛋白1在异位妊娠中的应用和产品 |
| CN113142126A (zh) * | 2020-12-22 | 2021-07-23 | 安徽医科大学 | 大鼠子宫内膜深度损伤模型的构建方法及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE432485B (sv) * | 1974-11-11 | 1984-04-02 | Carter Wallace | Sett att bestemma prolaktin och medel herfor |
| US4585740A (en) * | 1983-05-03 | 1986-04-29 | The Whittier Institute For Diabetes And Endocrinology | Prolactin immunoassay using synthetic peptide |
| GB9416415D0 (en) * | 1994-08-13 | 1994-10-05 | Kodak Ltd | Antenatel screening for pregnacy abnormalities |
| US20060046274A1 (en) * | 2004-08-31 | 2006-03-02 | Repromedix Corporation And Shimon Segal | Inhibin-A: a marker for differentiation, diagnosing and screening abnormal pregnancies |
| US20060228755A1 (en) * | 2004-12-22 | 2006-10-12 | Gerton George L | Ectopic pregnancy markers |
| CA2597271A1 (en) * | 2005-02-16 | 2006-08-24 | Dana-Farber Cancer Institute | Methods of detecting ovarian cancer |
| US8383351B2 (en) * | 2008-06-11 | 2013-02-26 | Oxford Brookes University | Antibody to inhibin/ activin β-B subunit |
-
2008
- 2008-07-02 AT AT08775831T patent/ATE538217T1/de active
- 2008-07-02 EP EP08775831A patent/EP2171091B1/de not_active Not-in-force
- 2008-07-02 JP JP2010514121A patent/JP2010531991A/ja active Pending
- 2008-07-02 WO PCT/GB2008/002282 patent/WO2009004340A2/en not_active Ceased
- 2008-07-02 US US12/667,320 patent/US20100285974A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20100285974A1 (en) | 2010-11-11 |
| WO2009004340A3 (en) | 2009-03-12 |
| EP2171091B1 (de) | 2011-12-21 |
| EP2171091A2 (de) | 2010-04-07 |
| WO2009004340A2 (en) | 2009-01-08 |
| JP2010531991A (ja) | 2010-09-30 |
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