BRPI0513714A - procedimento para caracterização estrutural de uma proteìna policlonal recombinante ou uma linhagem de célula policlonal - Google Patents

procedimento para caracterização estrutural de uma proteìna policlonal recombinante ou uma linhagem de célula policlonal

Info

Publication number
BRPI0513714A
BRPI0513714A BRPI0513714-4A BRPI0513714A BRPI0513714A BR PI0513714 A BRPI0513714 A BR PI0513714A BR PI0513714 A BRPI0513714 A BR PI0513714A BR PI0513714 A BRPI0513714 A BR PI0513714A
Authority
BR
Brazil
Prior art keywords
polyclonal
cell line
structural characterization
procedure
recombinant
Prior art date
Application number
BRPI0513714-4A
Other languages
English (en)
Inventor
Lone Kjaer Rasmussen
Torben Frandsen
Soren Kofoed Rasmussen
Peter Sejer Andersen
Original Assignee
Symphogen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symphogen As filed Critical Symphogen As
Publication of BRPI0513714A publication Critical patent/BRPI0513714A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Document Processing Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

PROCEDIMENTO PARA CARACTERIZAçãO ESTRUTURAL DE UMA PROTEìNA POLICLONAL. RECOMBINANTE OU UMA LINHAGEM DE CéLULA POLICLONAL. A presente invenção refere-se a uma plataforma de caracterizacão estrutural que pode ser empregada para avaliar a estabilidade de uma linhagem de célula policlonal durante a produção, bem como consistência de batelada para batelada dos produtos policlonais finais. A plataforma de caracterização estrutural é com base na análise genética bem como técnicas de caracterização de proteína que sozinha ou em combinação fornece a informação necessária para caracterizar a linhagem de célula policlonal e produtos finais. A coleção de proteínas homólogas diferentes a ser analisada com as técnicas de plataforma no caso de. por exemplo, um anticorpo policlonal recombinante ou uma mistura de anticorpos monoclonais.
BRPI0513714-4A 2004-07-20 2005-07-20 procedimento para caracterização estrutural de uma proteìna policlonal recombinante ou uma linhagem de célula policlonal BRPI0513714A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200401133 2004-07-20
DKPA200401991 2004-12-22
PCT/DK2005/000504 WO2006007853A2 (en) 2004-07-20 2005-07-20 A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line

Publications (1)

Publication Number Publication Date
BRPI0513714A true BRPI0513714A (pt) 2008-05-13

Family

ID=35427551

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513714-4A BRPI0513714A (pt) 2004-07-20 2005-07-20 procedimento para caracterização estrutural de uma proteìna policlonal recombinante ou uma linhagem de célula policlonal

Country Status (19)

Country Link
US (2) US8288109B2 (pt)
EP (2) EP2053408B1 (pt)
JP (1) JP4870667B2 (pt)
KR (1) KR101319848B1 (pt)
AT (2) ATE443870T1 (pt)
AU (1) AU2005263334C1 (pt)
BR (1) BRPI0513714A (pt)
CA (1) CA2574146C (pt)
DE (1) DE602005016818D1 (pt)
DK (2) DK1787126T3 (pt)
ES (2) ES2381531T3 (pt)
HK (2) HK1101043A1 (pt)
IL (2) IL180169A (pt)
MX (1) MX2007000551A (pt)
NO (1) NO20070931L (pt)
NZ (1) NZ552264A (pt)
PL (2) PL2053408T3 (pt)
RU (1) RU2426795C2 (pt)
WO (1) WO2006007853A2 (pt)

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KR101024443B1 (ko) 2003-01-07 2011-03-23 심포젠 에이/에스 재조합 폴리클로날 단백질의 제조 방법
TWI333977B (en) 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
BRPI0513706A (pt) 2004-07-20 2008-05-13 Symphogen As anticorpo policlonal recombinante anti-rhesus d e métodos de produção
WO2006007853A2 (en) 2004-07-20 2006-01-26 Symphogen A/S A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line
US7850965B2 (en) 2005-12-05 2010-12-14 Symphogen A/S Anti-orthopoxvirus recombinant polyclonal antibody
US8338376B2 (en) 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
ATE521704T1 (de) * 2007-03-01 2011-09-15 Symphogen As Verfahren zur klonierung verwandter antikörper
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US8821879B2 (en) 2009-09-04 2014-09-02 Xoma Technology Ltd. Anti-botulism antibody coformulations
AU2010305150A1 (en) * 2009-10-09 2012-04-05 Symphogen A/S Multiplex quantitation of individual recombinant proteins in a mixture by signature peptides and mass spectrometry
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Also Published As

Publication number Publication date
EP2053408B1 (en) 2012-03-07
AU2005263334A1 (en) 2006-01-26
HK1101043A1 (en) 2007-10-05
CA2574146A1 (en) 2006-01-26
HK1133076A1 (en) 2010-03-12
RU2007106050A (ru) 2008-08-27
ATE548657T1 (de) 2012-03-15
JP2008506960A (ja) 2008-03-06
IL180169A (en) 2011-04-28
KR20070032078A (ko) 2007-03-20
DK2053408T3 (da) 2012-06-04
PL2053408T3 (pl) 2012-08-31
ES2332524T3 (es) 2010-02-08
US20130203063A1 (en) 2013-08-08
NZ552264A (en) 2010-03-26
ES2381531T3 (es) 2012-05-29
AU2005263334C1 (en) 2011-01-20
DE602005016818D1 (de) 2009-11-05
NO20070931L (no) 2007-04-17
EP2053408A2 (en) 2009-04-29
EP2053408A3 (en) 2009-07-29
ATE443870T1 (de) 2009-10-15
MX2007000551A (es) 2007-03-30
EP1787126B1 (en) 2009-09-23
AU2005263334B2 (en) 2010-08-05
DK1787126T3 (da) 2009-12-21
EP1787126A2 (en) 2007-05-23
US20080131882A1 (en) 2008-06-05
IL180169A0 (en) 2007-06-03
IL203017A (en) 2013-08-29
WO2006007853A2 (en) 2006-01-26
RU2426795C2 (ru) 2011-08-20
PL1787126T3 (pl) 2010-03-31
JP4870667B2 (ja) 2012-02-08
WO2006007853A3 (en) 2006-05-18
US9029091B2 (en) 2015-05-12
CA2574146C (en) 2015-06-30
KR101319848B1 (ko) 2013-10-18
US8288109B2 (en) 2012-10-16

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06H Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette]

Free format text: REF. A RPI NO 2150 DE 20/03/2012. ANULACAO DA EXIGENCIA 6.6 POR TER SIDO INDEVIDA. REQUERENTE NAO APRESENTOU RESPOSTA A EXIGENCIA CONFORME DISPOE A RESOLUCAO 207 DE 24/04/2009, ENTRETANTO, A RESPOSTA CONSTA NO FORMULARIO DE DEPOSITO.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]