DE602005016818D1 - Verfahren zur charakterisierung einer polyklonalen zellinie - Google Patents

Verfahren zur charakterisierung einer polyklonalen zellinie

Info

Publication number
DE602005016818D1
DE602005016818D1 DE602005016818T DE602005016818T DE602005016818D1 DE 602005016818 D1 DE602005016818 D1 DE 602005016818D1 DE 602005016818 T DE602005016818 T DE 602005016818T DE 602005016818 T DE602005016818 T DE 602005016818T DE 602005016818 D1 DE602005016818 D1 DE 602005016818D1
Authority
DE
Germany
Prior art keywords
cell line
polyclonal
platform
polyclonal cell
characterizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005016818T
Other languages
English (en)
Inventor
Lone Kjar Rasmussen
Torben Frandsen
Soeren Kofoed Rasmussen
Peter Sejer Andersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symphogen AS
Original Assignee
Symphogen AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symphogen AS filed Critical Symphogen AS
Publication of DE602005016818D1 publication Critical patent/DE602005016818D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Document Processing Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE602005016818T 2004-07-20 2005-07-20 Verfahren zur charakterisierung einer polyklonalen zellinie Active DE602005016818D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200401133 2004-07-20
DKPA200401991 2004-12-22
PCT/DK2005/000504 WO2006007853A2 (en) 2004-07-20 2005-07-20 A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line

Publications (1)

Publication Number Publication Date
DE602005016818D1 true DE602005016818D1 (de) 2009-11-05

Family

ID=35427551

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005016818T Active DE602005016818D1 (de) 2004-07-20 2005-07-20 Verfahren zur charakterisierung einer polyklonalen zellinie

Country Status (19)

Country Link
US (2) US8288109B2 (de)
EP (2) EP2053408B1 (de)
JP (1) JP4870667B2 (de)
KR (1) KR101319848B1 (de)
AT (2) ATE443870T1 (de)
AU (1) AU2005263334C1 (de)
BR (1) BRPI0513714A (de)
CA (1) CA2574146C (de)
DE (1) DE602005016818D1 (de)
DK (2) DK1787126T3 (de)
ES (2) ES2381531T3 (de)
HK (2) HK1101043A1 (de)
IL (2) IL180169A (de)
MX (1) MX2007000551A (de)
NO (1) NO20070931L (de)
NZ (1) NZ552264A (de)
PL (2) PL2053408T3 (de)
RU (1) RU2426795C2 (de)
WO (1) WO2006007853A2 (de)

Families Citing this family (28)

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PT1583830E (pt) 2003-01-07 2006-11-30 Symphogen As Método para produzir proteínas policlonais recombinantes
TWI333977B (en) 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
AU2005263331B8 (en) 2004-07-20 2011-06-16 Symphogen A/S Anti-Rhesus D recombinant polyclonal antibody and methods of manufacture
KR101319848B1 (ko) 2004-07-20 2013-10-18 심포젠 에이/에스 재조합 폴리클로날 단백질 또는 폴리클로날 세포주의구조적 특성화 방법
US7850965B2 (en) 2005-12-05 2010-12-14 Symphogen A/S Anti-orthopoxvirus recombinant polyclonal antibody
US8338376B2 (en) 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
NZ578851A (en) 2007-03-01 2011-09-30 Symphogen As Method for cloning cognate antibodies
ES2582386T3 (es) * 2007-03-01 2016-09-12 Symphogen A/S Composiciones de anticuerpos recombinantes contra el receptor del factor de crecimiento epidérmico
EP2134747A2 (de) * 2007-03-06 2009-12-23 Symphogen A/S Rekombinante antikörper zur behandlung von infektionen mit dem respiratory syncytial virus
CN101951940A (zh) * 2007-03-15 2011-01-19 比奥根艾迪克Ma公司 自身免疫病的治疗
JP2008289483A (ja) * 2007-05-25 2008-12-04 Symphogen As 真核生物系において発現可能な形質転換体のスクリーニング
JP5941616B2 (ja) 2007-05-25 2016-06-29 シムフォゲン・アクティーゼルスカブSymphogen A/S 組み換えポリクローナルタンパク質を製造する方法
WO2009030237A2 (en) * 2007-09-07 2009-03-12 Symphogen A/S Methods for recombinant manufacturing of anti-rsv antibodies
US20090186423A1 (en) * 2007-11-22 2009-07-23 Symphogen A/S Method for Characterization of a Recombinant Polyclonal Protein
JP2011518790A (ja) * 2008-04-23 2011-06-30 シムフォゲン・アクティーゼルスカブ ポリクローナルタンパク質を製造する方法
BRPI0917352A2 (pt) * 2008-08-29 2017-08-22 Symphogen As Métodos para produção de uma biblioteca de pares cognatos que compreende sequências ligadas que codificam regiões variáveis e para gerar um vetor que codifica um anticorpo quimérico com regiões de seres humanos constantes e regiões variáveis não humanas, biblioteca de vetores, e método para produção de uma biblioteca de sequências de imunoglobulina derivadas de aves
CN102137874B (zh) 2008-08-29 2015-02-18 西福根有限公司 抗表皮生长因子受体的重组抗体组合物
US8821879B2 (en) 2009-09-04 2014-09-02 Xoma Technology Ltd. Anti-botulism antibody coformulations
AU2010305150A1 (en) * 2009-10-09 2012-04-05 Symphogen A/S Multiplex quantitation of individual recombinant proteins in a mixture by signature peptides and mass spectrometry
MX360403B (es) * 2010-04-15 2018-10-31 Abbvie Inc Proteinas de union a amiloide beta.
WO2012059858A1 (en) 2010-11-01 2012-05-10 Symphogen A/S Anti-her3 antibodies and compositions
EP2953970A4 (de) 2013-02-08 2016-06-29 Misfolding Diagnostics Inc Transthyretinantikörper und verwendungen davon
UY35517A (es) 2013-04-04 2014-10-31 Mabxience S A Un procedimiento para aumentar la formación de ácido piroglutamico de una proteína
WO2015093925A1 (es) * 2013-12-19 2015-06-25 CASTRO ALDRETE, Jorge Isaac Método de producción de anticuerpos específicos
TW201623331A (zh) * 2014-03-12 2016-07-01 普羅帝納生物科學公司 抗黑色素瘤細胞黏著分子(mcam)抗體類及使用彼等之相關方法
US11680948B2 (en) 2016-08-12 2023-06-20 Abreos Biosciences, Inc. Detection and quantification of natalizumab
SG11202012713RA (en) * 2018-06-22 2021-01-28 Genmab As Method for producing a controlled mixture of two or more different antibodies
CN112816595A (zh) * 2021-01-06 2021-05-18 海默斯(重庆)医学生物技术有限公司 一种重组角蛋白液体制剂及其纯度检测方法

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KR101319848B1 (ko) 2004-07-20 2013-10-18 심포젠 에이/에스 재조합 폴리클로날 단백질 또는 폴리클로날 세포주의구조적 특성화 방법
AU2005263331B8 (en) 2004-07-20 2011-06-16 Symphogen A/S Anti-Rhesus D recombinant polyclonal antibody and methods of manufacture
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Also Published As

Publication number Publication date
WO2006007853A3 (en) 2006-05-18
CA2574146C (en) 2015-06-30
ATE443870T1 (de) 2009-10-15
HK1133076A1 (en) 2010-03-12
PL1787126T3 (pl) 2010-03-31
KR20070032078A (ko) 2007-03-20
EP2053408A2 (de) 2009-04-29
PL2053408T3 (pl) 2012-08-31
AU2005263334C1 (en) 2011-01-20
US9029091B2 (en) 2015-05-12
EP1787126B1 (de) 2009-09-23
ATE548657T1 (de) 2012-03-15
US8288109B2 (en) 2012-10-16
KR101319848B1 (ko) 2013-10-18
AU2005263334A1 (en) 2006-01-26
EP2053408A3 (de) 2009-07-29
IL203017A (en) 2013-08-29
AU2005263334B2 (en) 2010-08-05
ES2332524T3 (es) 2010-02-08
IL180169A (en) 2011-04-28
BRPI0513714A (pt) 2008-05-13
CA2574146A1 (en) 2006-01-26
DK1787126T3 (da) 2009-12-21
JP2008506960A (ja) 2008-03-06
HK1101043A1 (en) 2007-10-05
RU2426795C2 (ru) 2011-08-20
EP2053408B1 (de) 2012-03-07
JP4870667B2 (ja) 2012-02-08
US20080131882A1 (en) 2008-06-05
MX2007000551A (es) 2007-03-30
DK2053408T3 (da) 2012-06-04
EP1787126A2 (de) 2007-05-23
IL180169A0 (en) 2007-06-03
WO2006007853A2 (en) 2006-01-26
ES2381531T3 (es) 2012-05-29
NZ552264A (en) 2010-03-26
NO20070931L (no) 2007-04-17
RU2007106050A (ru) 2008-08-27
US20130203063A1 (en) 2013-08-08

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