DE69328135D1 - Menschliche monoklonale Antikörper gegen Rhesus D und Zellinien die diese produzieren - Google Patents

Menschliche monoklonale Antikörper gegen Rhesus D und Zellinien die diese produzieren

Info

Publication number
DE69328135D1
DE69328135D1 DE69328135T DE69328135T DE69328135D1 DE 69328135 D1 DE69328135 D1 DE 69328135D1 DE 69328135 T DE69328135 T DE 69328135T DE 69328135 T DE69328135 T DE 69328135T DE 69328135 D1 DE69328135 D1 DE 69328135D1
Authority
DE
Germany
Prior art keywords
rhesus
produce
cell lines
human monoclonal
monoclonal antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69328135T
Other languages
English (en)
Inventor
Roland Beliard
Ulf Bethke
Dominique Bourel
Ahmed Bouzidi
Herve Broly
Peter Byrne
Magali Holuigue
Michael Kloft
Detlef Rohm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotest Pharma GmbH
AETSRN
Original Assignee
Biotest Pharma GmbH
AETSRN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9207893A external-priority patent/FR2692786B1/fr
Priority claimed from DE19924224357 external-priority patent/DE4224357C2/de
Application filed by Biotest Pharma GmbH, AETSRN filed Critical Biotest Pharma GmbH
Priority to DE69328135T priority Critical patent/DE69328135D1/de
Application granted granted Critical
Publication of DE69328135D1 publication Critical patent/DE69328135D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69328135T 1992-06-26 1993-06-22 Menschliche monoklonale Antikörper gegen Rhesus D und Zellinien die diese produzieren Expired - Lifetime DE69328135D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE69328135T DE69328135D1 (de) 1992-06-26 1993-06-22 Menschliche monoklonale Antikörper gegen Rhesus D und Zellinien die diese produzieren

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9207893A FR2692786B1 (fr) 1992-06-26 1992-06-26 Anticorps monoclonaux humains anti-rhesus d et lignees cellulaires les produisant.
DE19924224357 DE4224357C2 (de) 1992-07-23 1992-07-23 Arzneimittel zur Prophylaxe von HDN, enthaltend menschliche monoclonale anti-Rhesus (D)-Antikörper
DE69328135T DE69328135D1 (de) 1992-06-26 1993-06-22 Menschliche monoklonale Antikörper gegen Rhesus D und Zellinien die diese produzieren

Publications (1)

Publication Number Publication Date
DE69328135D1 true DE69328135D1 (de) 2000-04-27

Family

ID=25916870

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69328135T Expired - Lifetime DE69328135D1 (de) 1992-06-26 1993-06-22 Menschliche monoklonale Antikörper gegen Rhesus D und Zellinien die diese produzieren

Country Status (12)

Country Link
US (1) US5851524A (de)
EP (1) EP0576093B1 (de)
AT (1) ATE191006T1 (de)
AU (1) AU678364B2 (de)
BR (1) BR9305557A (de)
CA (1) CA2116246A1 (de)
DE (1) DE69328135D1 (de)
FI (1) FI940811A (de)
HU (1) HUT68624A (de)
MX (1) MX9303839A (de)
PL (1) PL302438A1 (de)
WO (1) WO1994000561A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
FR2858235B1 (fr) 2003-07-31 2006-02-17 Lab Francais Du Fractionnement Utilisation d'anticorps optimises en adcc pour traiter les patients faibles repondeurs
FR2861078B1 (fr) * 2003-10-16 2007-09-21 Lab Francais Du Fractionnement NOUVELLES IgG3 UTILES POUR STIMULER LA PHAGOCYTOSE
EP1967529A1 (de) 2004-07-20 2008-09-10 Symphogen A/S Rekombinanter polyklonaler Anti-Rhesus-D-Antikörper und Herstellungsverfahren
ATE548657T1 (de) 2004-07-20 2012-03-15 Symphogen As Prozedur zur strukturellen charakterisierung rekombinanter polyclonaler proteine oder einer polyclonalen zelllinie
TWI391399B (zh) 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
JP5064558B2 (ja) 2007-06-01 2012-10-31 エフ．ホフマン−ラ ロシュ アーゲー 免疫グロブリン精製
CA2639003A1 (en) * 2008-08-20 2010-02-20 Canadian Blood Services Inhibition of fc.gamma.r-mediated phagocytosis with reduced immunoglobulin preparations
JP2012513425A (ja) 2008-12-22 2012-06-14 エフ．ホフマン−ラ ロシュ アーゲー 免疫グロブリンの精製
US20110059079A1 (en) * 2009-09-04 2011-03-10 Xoma Technology Ltd. Antibody Coformulations
WO2011028961A2 (en) 2009-09-04 2011-03-10 Xoma Technology Ltd. Anti-botulism antibody coformulations
CN106267405B (zh) * 2016-07-01 2019-02-19 翁炳焕 母胎血型不合溶血病治疗仪

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH652145A5 (de) * 1982-01-22 1985-10-31 Sandoz Ag Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
GB8722018D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8722019D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8722020D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8906129D0 (en) * 1989-03-17 1989-05-04 Central Blood Lab Authority Pharmaceutical preparations

Also Published As

Publication number Publication date
HU9400862D0 (en) 1994-06-28
WO1994000561A1 (en) 1994-01-06
CA2116246A1 (en) 1994-01-06
FI940811A0 (fi) 1994-02-21
AU4419793A (en) 1994-01-24
EP0576093A1 (de) 1993-12-29
US5851524A (en) 1998-12-22
MX9303839A (es) 1994-08-31
ATE191006T1 (de) 2000-04-15
PL302438A1 (en) 1994-07-25
EP0576093B1 (de) 2000-03-22
HUT68624A (en) 1995-07-28
BR9305557A (pt) 1997-03-25
AU678364B2 (en) 1997-05-29
FI940811A (fi) 1994-02-21

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Legal Events

Date Code Title Description
8332 No legal effect for de