ATE191006T1 - Menschliche monoklonale antikörper gegen rhesus d und zellinien die diese produzieren - Google Patents

Menschliche monoklonale antikörper gegen rhesus d und zellinien die diese produzieren

Info

Publication number
ATE191006T1
ATE191006T1 AT93201797T AT93201797T ATE191006T1 AT E191006 T1 ATE191006 T1 AT E191006T1 AT 93201797 T AT93201797 T AT 93201797T AT 93201797 T AT93201797 T AT 93201797T AT E191006 T1 ATE191006 T1 AT E191006T1
Authority
AT
Austria
Prior art keywords
rhesus
produce
cell lines
human monoclonal
monoclonal antibodies
Prior art date
Application number
AT93201797T
Other languages
English (en)
Inventor
Roland Beliard
Ulf Bethke
Dominique Bourel
Ahmed Bouzidi
Herve Broly
Peter Byrne
Magali Holuigue
Michael Kloft
Detlef Rohm
Original Assignee
Aetsrn
Biotest Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9207893A external-priority patent/FR2692786B1/fr
Priority claimed from DE19924224357 external-priority patent/DE4224357C2/de
Application filed by Aetsrn, Biotest Pharma Gmbh filed Critical Aetsrn
Application granted granted Critical
Publication of ATE191006T1 publication Critical patent/ATE191006T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT93201797T 1992-06-26 1993-06-22 Menschliche monoklonale antikörper gegen rhesus d und zellinien die diese produzieren ATE191006T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9207893A FR2692786B1 (fr) 1992-06-26 1992-06-26 Anticorps monoclonaux humains anti-rhesus d et lignees cellulaires les produisant.
DE19924224357 DE4224357C2 (de) 1992-07-23 1992-07-23 Arzneimittel zur Prophylaxe von HDN, enthaltend menschliche monoclonale anti-Rhesus (D)-Antikörper

Publications (1)

Publication Number Publication Date
ATE191006T1 true ATE191006T1 (de) 2000-04-15

Family

ID=25916870

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93201797T ATE191006T1 (de) 1992-06-26 1993-06-22 Menschliche monoklonale antikörper gegen rhesus d und zellinien die diese produzieren

Country Status (12)

Country Link
US (1) US5851524A (de)
EP (1) EP0576093B1 (de)
AT (1) ATE191006T1 (de)
AU (1) AU678364B2 (de)
BR (1) BR9305557A (de)
CA (1) CA2116246A1 (de)
DE (1) DE69328135D1 (de)
FI (1) FI940811A (de)
HU (1) HUT68624A (de)
MX (1) MX9303839A (de)
PL (1) PL302438A1 (de)
WO (1) WO1994000561A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
FR2858235B1 (fr) * 2003-07-31 2006-02-17 Lab Francais Du Fractionnement Utilisation d'anticorps optimises en adcc pour traiter les patients faibles repondeurs
FR2861078B1 (fr) * 2003-10-16 2007-09-21 Lab Francais Du Fractionnement NOUVELLES IgG3 UTILES POUR STIMULER LA PHAGOCYTOSE
DE602005016818D1 (de) 2004-07-20 2009-11-05 Symphogen As Verfahren zur charakterisierung einer polyklonalen zellinie
CA2574062A1 (en) 2004-07-20 2006-01-26 Symphogen A/S Anti-rhesus d recombinant polyclonal antibody and methods of manufacture
TWI391399B (zh) 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
WO2008145351A1 (en) 2007-06-01 2008-12-04 F. Hoffmann-La Roche Ag Immunoglobulin purification
CA2639003A1 (en) * 2008-08-20 2010-02-20 Canadian Blood Services Inhibition of fc.gamma.r-mediated phagocytosis with reduced immunoglobulin preparations
BRPI0923541A2 (pt) 2008-12-22 2016-01-26 Hoffmann La Roche purificação de imunoglobulina
WO2011028961A2 (en) 2009-09-04 2011-03-10 Xoma Technology Ltd. Anti-botulism antibody coformulations
US20110059079A1 (en) * 2009-09-04 2011-03-10 Xoma Technology Ltd. Antibody Coformulations
CN106267405B (zh) * 2016-07-01 2019-02-19 翁炳焕 母胎血型不合溶血病治疗仪

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH652145A5 (de) * 1982-01-22 1985-10-31 Sandoz Ag Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
GB8722018D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8722020D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8722019D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8906129D0 (en) * 1989-03-17 1989-05-04 Central Blood Lab Authority Pharmaceutical preparations

Also Published As

Publication number Publication date
EP0576093B1 (de) 2000-03-22
DE69328135D1 (de) 2000-04-27
BR9305557A (pt) 1997-03-25
CA2116246A1 (en) 1994-01-06
MX9303839A (es) 1994-08-31
PL302438A1 (en) 1994-07-25
AU4419793A (en) 1994-01-24
HUT68624A (en) 1995-07-28
FI940811A0 (fi) 1994-02-21
US5851524A (en) 1998-12-22
WO1994000561A1 (en) 1994-01-06
AU678364B2 (en) 1997-05-29
EP0576093A1 (de) 1993-12-29
HU9400862D0 (en) 1994-06-28
FI940811A (fi) 1994-02-21

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties