GEP20043233B - Composition Containing Blocking Monoclonal Antibody VLA-1 - Google Patents

Composition Containing Blocking Monoclonal Antibody VLA-1

Info

Publication number
GEP20043233B
GEP20043233B GEAP20006273A GEAP2000006273A GEP20043233B GE P20043233 B GEP20043233 B GE P20043233B GE AP20006273 A GEAP20006273 A GE AP20006273A GE AP2000006273 A GEAP2000006273 A GE AP2000006273A GE P20043233 B GEP20043233 B GE P20043233B
Authority
GE
Georgia
Prior art keywords
monoclonal antibody
composition containing
blocking monoclonal
containing blocking
vla
Prior art date
Application number
GEAP20006273A
Inventor
Koteliansky, (Us) Victor
Philip Gotwals
Lobb, (Us) Roy
Fougerolles Antonin De (Ca)
Original Assignee
Biogen Inc Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc Us filed Critical Biogen Inc Us
Publication of GEP20043233B publication Critical patent/GEP20043233B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C07K2316/96—
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

1. Technical Result Increase in treatment of inflammatory disorders, particularly the treatment of arthritis. 2. Essence A composition is disclosed blocking antibody which is capable of binding an epitope of VLA-1 3. Field of Application Medicine.
GEAP20006273A 1999-06-01 2000-06-01 Composition Containing Blocking Monoclonal Antibody VLA-1 GEP20043233B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13703899P 1999-06-01 1999-06-01
US18533699P 1999-06-01 1999-06-01

Publications (1)

Publication Number Publication Date
GEP20043233B true GEP20043233B (en) 2004-05-25

Family

ID=82020314

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP20006273A GEP20043233B (en) 1999-06-01 2000-06-01 Composition Containing Blocking Monoclonal Antibody VLA-1

Country Status (1)

Country Link
GE (1) GEP20043233B (en)

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