MX9303839A - Anticuerpos monoclonales humanos anti-rhesus (d) y lineas celulares productoras de los mismos. - Google Patents

Anticuerpos monoclonales humanos anti-rhesus (d) y lineas celulares productoras de los mismos.

Info

Publication number
MX9303839A
MX9303839A MX9303839A MX9303839A MX9303839A MX 9303839 A MX9303839 A MX 9303839A MX 9303839 A MX9303839 A MX 9303839A MX 9303839 A MX9303839 A MX 9303839A MX 9303839 A MX9303839 A MX 9303839A
Authority
MX
Mexico
Prior art keywords
rhesus
cell lines
human monoclonal
monoclonal antibodies
antibodies anti
Prior art date
Application number
MX9303839A
Other languages
English (en)
Inventor
Ahmed Bouzidi
Herve Broly
Peter Byrne
Magali Holuigue
Michel Kloft
Detlef Rohm
Roland Beliard
Ulf Bethke
Dominique Bourel
Original Assignee
Aetsrn
Biotest Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9207893A external-priority patent/FR2692786B1/fr
Priority claimed from DE19924224357 external-priority patent/DE4224357C2/de
Application filed by Aetsrn, Biotest Pharma Gmbh filed Critical Aetsrn
Publication of MX9303839A publication Critical patent/MX9303839A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La invención se relaciona con dos anticuerpos monoclonales humanos de las sub-clases IgGI e IgG3 contra el antogeno Rhesus D, así como con una composición farmacéutica que contienen una mezcla de dichos anticuerpos y que está destinada muy particularmente a la profilaxis de la enfermedad hemolítica del recién nacido. La invención se relaciona también a la líneas de células heterohibridomas que producen estos anticuerpos, las cuales fueron despositadas en 'Deutshe Sammlung von Milkroorganismen und zellkulturen' con los números de acceso DSM AC 2039 Y DSM AC 2040.
MX9303839A 1992-06-26 1993-06-25 Anticuerpos monoclonales humanos anti-rhesus (d) y lineas celulares productoras de los mismos. MX9303839A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9207893A FR2692786B1 (fr) 1992-06-26 1992-06-26 Anticorps monoclonaux humains anti-rhesus d et lignees cellulaires les produisant.
DE19924224357 DE4224357C2 (de) 1992-07-23 1992-07-23 Arzneimittel zur Prophylaxe von HDN, enthaltend menschliche monoclonale anti-Rhesus (D)-Antikörper

Publications (1)

Publication Number Publication Date
MX9303839A true MX9303839A (es) 1994-08-31

Family

ID=25916870

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9303839A MX9303839A (es) 1992-06-26 1993-06-25 Anticuerpos monoclonales humanos anti-rhesus (d) y lineas celulares productoras de los mismos.

Country Status (12)

Country Link
US (1) US5851524A (es)
EP (1) EP0576093B1 (es)
AT (1) ATE191006T1 (es)
AU (1) AU678364B2 (es)
BR (1) BR9305557A (es)
CA (1) CA2116246A1 (es)
DE (1) DE69328135D1 (es)
FI (1) FI940811A0 (es)
HU (1) HUT68624A (es)
MX (1) MX9303839A (es)
PL (1) PL302438A1 (es)
WO (1) WO1994000561A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
FR2858235B1 (fr) 2003-07-31 2006-02-17 Lab Francais Du Fractionnement Utilisation d'anticorps optimises en adcc pour traiter les patients faibles repondeurs
FR2861078B1 (fr) * 2003-10-16 2007-09-21 Lab Francais Du Fractionnement NOUVELLES IgG3 UTILES POUR STIMULER LA PHAGOCYTOSE
ES2332524T3 (es) 2004-07-20 2010-02-08 Symphogen A/S Un procedimiento para la caracterizacion de una linea celular policlonal.
EP1771483A1 (en) 2004-07-20 2007-04-11 Symphogen A/S Anti-rhesus d recombinant polyclonal antibody and methods of manufacture
TWI320788B (en) 2005-05-25 2010-02-21 Hoffmann La Roche Method for the purification of antibodies
BRPI0812288A2 (pt) 2007-06-01 2014-11-25 Hoffmann La Roche Purificação de imunoglobulina.
CA2639003A1 (en) * 2008-08-20 2010-02-20 Canadian Blood Services Inhibition of fc.gamma.r-mediated phagocytosis with reduced immunoglobulin preparations
AU2009331897A1 (en) 2008-12-22 2010-07-01 F. Hoffmann-La Roche Ag Immunoglobulin purification
WO2011028962A1 (en) * 2009-09-04 2011-03-10 Xoma Technology Ltd. Antibody coformulations
WO2011028961A2 (en) 2009-09-04 2011-03-10 Xoma Technology Ltd. Anti-botulism antibody coformulations
CN106267405B (zh) * 2016-07-01 2019-02-19 翁炳焕 母胎血型不合溶血病治疗仪

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH652145A5 (de) * 1982-01-22 1985-10-31 Sandoz Ag Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
GB8722020D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8722018D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8722019D0 (en) * 1987-09-18 1987-10-28 Central Blood Lab Authority Human anti-rh(d)monoclonal antibodies
GB8906129D0 (en) * 1989-03-17 1989-05-04 Central Blood Lab Authority Pharmaceutical preparations

Also Published As

Publication number Publication date
HU9400862D0 (en) 1994-06-28
WO1994000561A1 (en) 1994-01-06
AU678364B2 (en) 1997-05-29
FI940811A (fi) 1994-02-21
US5851524A (en) 1998-12-22
BR9305557A (pt) 1997-03-25
FI940811A0 (fi) 1994-02-21
EP0576093A1 (en) 1993-12-29
EP0576093B1 (en) 2000-03-22
AU4419793A (en) 1994-01-24
ATE191006T1 (de) 2000-04-15
PL302438A1 (en) 1994-07-25
HUT68624A (en) 1995-07-28
DE69328135D1 (de) 2000-04-27
CA2116246A1 (en) 1994-01-06

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Legal Events

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