ATE514072T1 - Verfahren zur bestimmung von teilchen in einer flüssigen probe - Google Patents

Verfahren zur bestimmung von teilchen in einer flüssigen probe

Info

Publication number
ATE514072T1
ATE514072T1 AT08101764T AT08101764T ATE514072T1 AT E514072 T1 ATE514072 T1 AT E514072T1 AT 08101764 T AT08101764 T AT 08101764T AT 08101764 T AT08101764 T AT 08101764T AT E514072 T1 ATE514072 T1 AT E514072T1
Authority
AT
Austria
Prior art keywords
domain
electromagnetic signals
liquid sample
assessment
exposing
Prior art date
Application number
AT08101764T
Other languages
English (en)
Inventor
Frans Ejner Ravn Hansen
Martin Glensbjerg
Boerkur Arnvidarson
Jesper Myron Jeppesen
Original Assignee
Chemometec As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26064130&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE514072(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chemometec As filed Critical Chemometec As
Application granted granted Critical
Publication of ATE514072T1 publication Critical patent/ATE514072T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02—Food
    • G01N33/04—Dairy products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N2015/025—Methods for single or grouped particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1452—Adjustment of focus; Alignment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/5907—Densitometers
    • G01N2021/5957—Densitometers using an image detector type detector, e.g. CCD
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6491—Measuring fluorescence and transmission; Correcting inner filter effect

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Plasma & Fusion (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Signal Processing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Dairy Products (AREA)
AT08101764T 1997-05-05 1998-05-05 Verfahren zur bestimmung von teilchen in einer flüssigen probe ATE514072T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK50997 1997-05-05
DK143197 1997-12-09

Publications (1)

Publication Number Publication Date
ATE514072T1 true ATE514072T1 (de) 2011-07-15

Family

ID=26064130

Family Applications (5)

Application Number Title Priority Date Filing Date
AT98921022T ATE398185T1 (de) 1997-05-05 1998-05-05 Verfahren und system zur bestimmung von somazellen in milch
AT08101757T ATE555375T1 (de) 1997-05-05 1998-05-05 Verfahren und vorrichtung zur bestimmung von teilchen in einer flüssigen probe
AT98919085T ATE236387T1 (de) 1997-05-05 1998-05-05 Bestimmung von partikeln in einer flüssigen probe
AT08101764T ATE514072T1 (de) 1997-05-05 1998-05-05 Verfahren zur bestimmung von teilchen in einer flüssigen probe
AT08101755T ATE514071T1 (de) 1997-05-05 1998-05-05 Verfahren zur bestimmung von biologischen teilchen im blut

Family Applications Before (3)

Application Number Title Priority Date Filing Date
AT98921022T ATE398185T1 (de) 1997-05-05 1998-05-05 Verfahren und system zur bestimmung von somazellen in milch
AT08101757T ATE555375T1 (de) 1997-05-05 1998-05-05 Verfahren und vorrichtung zur bestimmung von teilchen in einer flüssigen probe
AT98919085T ATE236387T1 (de) 1997-05-05 1998-05-05 Bestimmung von partikeln in einer flüssigen probe

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT08101755T ATE514071T1 (de) 1997-05-05 1998-05-05 Verfahren zur bestimmung von biologischen teilchen im blut

Country Status (11)

Country Link
US (10) US6710879B1 (de)
EP (11) EP1936351A3 (de)
JP (4) JP2002503097A (de)
AT (5) ATE398185T1 (de)
AU (2) AU737298B2 (de)
CA (2) CA2288801C (de)
DE (2) DE69812928T2 (de)
DK (2) DK1933128T3 (de)
IL (1) IL132688A (de)
NZ (2) NZ500686A (de)
WO (2) WO1998050777A1 (de)

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US8081312B2 (en) 2011-12-20
US6710879B1 (en) 2004-03-23
US20080248965A1 (en) 2008-10-09
NZ500686A (en) 2001-05-25
ATE398185T1 (de) 2008-07-15
EP1180676A3 (de) 2003-05-21
US20080246946A1 (en) 2008-10-09
EP1180677A2 (de) 2002-02-20
CA2288996C (en) 2009-07-21
EP1936351A2 (de) 2008-06-25
EP1180675A2 (de) 2002-02-20
US20060256340A1 (en) 2006-11-16
NZ500687A (en) 2001-05-25
WO1998050777A1 (en) 1998-11-12
IL132688A (en) 2005-08-31
US20040246483A1 (en) 2004-12-09
US20120223260A1 (en) 2012-09-06
US20080248964A1 (en) 2008-10-09
US8125643B2 (en) 2012-02-28
DE69812928D1 (de) 2003-05-08
CA2288996A1 (en) 1998-11-12
AU737298B2 (en) 2001-08-16
AU7372298A (en) 1998-11-27
EP1935983A3 (de) 2008-07-09
US7068365B2 (en) 2006-06-27
EP1947442A3 (de) 2008-07-30
ATE236387T1 (de) 2003-04-15
CA2288801C (en) 2012-11-06
EP0980516B1 (de) 2003-04-02
AU7205798A (en) 1998-11-27
EP1933127A1 (de) 2008-06-18
DE69812928T2 (de) 2004-03-04
EP1933128A2 (de) 2008-06-18
DK0980516T3 (da) 2003-04-22
JP2009258113A (ja) 2009-11-05
US8432550B2 (en) 2013-04-30
EP0980516A1 (de) 2000-02-23
EP0983378B1 (de) 2008-06-11
AU739824B2 (en) 2001-10-18
EP1180675A3 (de) 2003-05-21
US6919960B2 (en) 2005-07-19
EP1180676A2 (de) 2002-02-20
US20050225766A1 (en) 2005-10-13
CA2288801A1 (en) 1998-11-12
DE69839605D1 (de) 2008-07-24
EP1947442A2 (de) 2008-07-23
WO1998050577A1 (en) 1998-11-12
EP1947443A2 (de) 2008-07-23
ATE555375T1 (de) 2012-05-15
EP1933128A3 (de) 2008-06-25
JP2001526780A (ja) 2001-12-18
US8363221B2 (en) 2013-01-29
EP1936351A3 (de) 2008-07-02
EP1935983A2 (de) 2008-06-25
DK1933128T3 (da) 2012-07-23
EP1947443A3 (de) 2008-07-30
EP0983378A1 (de) 2000-03-08
ATE514071T1 (de) 2011-07-15

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