ATE211824T1 - Verfahren zur isolierung, detektion oder quantifizierung eines analyten in einem medium - Google Patents

Verfahren zur isolierung, detektion oder quantifizierung eines analyten in einem medium

Info

Publication number
ATE211824T1
ATE211824T1 AT98905473T AT98905473T ATE211824T1 AT E211824 T1 ATE211824 T1 AT E211824T1 AT 98905473 T AT98905473 T AT 98905473T AT 98905473 T AT98905473 T AT 98905473T AT E211824 T1 ATE211824 T1 AT E211824T1
Authority
AT
Austria
Prior art keywords
analyte
reagent
medium
isolation
receptor
Prior art date
Application number
AT98905473T
Other languages
English (en)
Inventor
Agnes Perrin
Alain Theretz
Bernard Mandrand
Original Assignee
Bio Merieux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Merieux filed Critical Bio Merieux
Application granted granted Critical
Publication of ATE211824T1 publication Critical patent/ATE211824T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
    • B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/801—Electron dense compounds, e.g. ferritin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
AT98905473T 1997-01-30 1998-01-30 Verfahren zur isolierung, detektion oder quantifizierung eines analyten in einem medium ATE211824T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9701313A FR2758884B1 (fr) 1997-01-30 1997-01-30 Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
PCT/FR1998/000182 WO1998034116A1 (fr) 1997-01-30 1998-01-30 Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu

Publications (1)

Publication Number Publication Date
ATE211824T1 true ATE211824T1 (de) 2002-01-15

Family

ID=9503365

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98905473T ATE211824T1 (de) 1997-01-30 1998-01-30 Verfahren zur isolierung, detektion oder quantifizierung eines analyten in einem medium

Country Status (9)

Country Link
US (1) US6342396B1 (de)
EP (1) EP0965045B1 (de)
JP (1) JP4053092B2 (de)
AT (1) ATE211824T1 (de)
AU (1) AU6104598A (de)
CA (1) CA2280187A1 (de)
DE (1) DE69803443T2 (de)
FR (1) FR2758884B1 (de)
WO (1) WO1998034116A1 (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US7285422B1 (en) 1997-01-23 2007-10-23 Sequenom, Inc. Systems and methods for preparing and analyzing low volume analyte array elements
EP0937096B1 (de) 1996-11-06 2004-02-04 Sequenom, Inc. Verfahren zur massenspektrometrie
AU735416B2 (en) 1996-11-06 2001-07-05 Sequenom, Inc. Dna diagnostics based on mass spectrometry
AUPP103497A0 (en) * 1997-12-19 1998-01-15 Panbio Pty Ltd Assay apparatus
FR2777355B1 (fr) 1998-04-10 2000-05-12 Bio Merieux Procede de fixation d'une molecule biologique sur la surface d'un support constitue de silice ou d'oxyde metallique
FR2790092B1 (fr) * 1999-02-24 2001-03-30 Commissariat Energie Atomique Procede de determination d'un analyte present dans une solution
US7390675B2 (en) * 1999-10-15 2008-06-24 Christopher Feistel Multi-functional and configurable assay
US6136549A (en) * 1999-10-15 2000-10-24 Feistel; Christopher C. systems and methods for performing magnetic chromatography assays
US7371584B2 (en) * 1999-10-15 2008-05-13 Wavesence, Inc. Multi-functional and configurable assay
CA2426686A1 (en) 2000-10-30 2002-07-18 Sequenom, Inc. Method and apparatus for delivery of submicroliter volumes onto a substrate
FR2817343B1 (fr) * 2000-11-29 2003-05-09 Commissariat Energie Atomique Procede et dispositifs de transport et de concentration d'un analyte present dans un echantillon
US20030092029A1 (en) * 2001-06-06 2003-05-15 Lee Josephson Magneitc-nanoparticle conjugates and methods of use
US6780602B2 (en) * 2001-11-01 2004-08-24 Microbiosystems, Limited Partnership Taxonomic identification of pathogenic microorganisms and their toxic proteins
US7122384B2 (en) * 2002-11-06 2006-10-17 E. I. Du Pont De Nemours And Company Resonant light scattering microparticle methods
CN1280428C (zh) * 2003-05-19 2006-10-18 清华大学 一种基于微小颗粒的生物芯片系统及其应用
TWI230760B (en) * 2003-07-29 2005-04-11 Univ Tsinghua Electrowetting electrode design with electromagnetic field for actuation of the magnetic-beads biochemical detection system
FR2863626B1 (fr) * 2003-12-15 2006-08-04 Commissariat Energie Atomique Procede et dispositif de division d'un echantillon biologique par effet magnetique
US7115524B2 (en) * 2004-05-17 2006-10-03 Micron Technology, Inc. Methods of processing a semiconductor substrate
US9494581B2 (en) 2004-08-24 2016-11-15 University Of Wyoming System and method for Raman spectroscopy assay using paramagnetic particles
US7818350B2 (en) 2005-02-28 2010-10-19 Yahoo! Inc. System and method for creating a collaborative playlist
US7781228B2 (en) * 2005-04-07 2010-08-24 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
JP5021629B2 (ja) * 2005-05-09 2012-09-12 ザ ジェネラル ホスピタル コーポレイション 水の緩和に基づくセンサ
CN100529752C (zh) * 2005-06-24 2009-08-19 财团法人工业技术研究院 使用磁性材料的分析方法及分析样品中待测物质的装置
US20070020699A1 (en) * 2005-07-19 2007-01-25 Idexx Laboratories, Inc. Lateral flow assay and device using magnetic particles
EP1932009B1 (de) 2005-08-31 2014-02-12 T2 Biosystems, Inc. Nmr-einrichtung zur detektion von analyten unter beteiligung von magnetischen teilchen
US8034634B2 (en) 2005-11-16 2011-10-11 Rex Chih-Yih Hong Ultra-sensitive magnetoreduction measurement system and ultra-sensitive, wash-free assay using the same
US20070166730A1 (en) 2006-01-19 2007-07-19 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
US10488408B2 (en) * 2006-05-09 2019-11-26 Koninklijke Philips N.V. Detection of target molecules in a sample by using a magnetic field
CA2669045A1 (en) 2006-11-08 2008-05-15 T2 Biosystems, Inc. Nmr systems for in vivo detection of analytes
US20110070657A1 (en) * 2007-08-17 2011-03-24 The General Hospital Corporation Detecting ions and measuring ion concentrations
WO2009039122A2 (en) 2007-09-17 2009-03-26 Sequenom, Inc. Integrated robotic sample transfer device
US8421458B2 (en) 2007-09-28 2013-04-16 T2 Biosystems, Inc. NMR diagnostics by means of a plastic sample container
US8519708B2 (en) * 2007-11-06 2013-08-27 T2 Biosystems, Inc. Small magnet and RF coil for magnetic resonance relaxometry
EP2246702B1 (de) * 2007-12-03 2015-10-07 Tamagawa Seiki Co., Ltd. Biosensing-verfahren unter verwendung beschichteter magnetischer mikropartikel und bei dem verfahren zu verwendende biosensing-vorrichtung
WO2010033452A2 (en) * 2008-09-19 2010-03-25 Delaware State University Foundation, Inc. Mono-and multi-element coded libs assays and methods
CA2741550C (en) 2008-10-29 2018-12-04 T2 Biosystems, Inc. Nmr detection of coagulation time
US20110086436A1 (en) * 2009-10-09 2011-04-14 Electronics And Telecommunications Research Institute Method for detecting antigen, and apparatus for detecting antigen using the same, and microfluidic chip using the same
EP3974831A1 (de) 2010-10-22 2022-03-30 T2 Biosystems, Inc. Verfahren zum nachweis eines bakteriums in einer vollblutprobe
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8409807B2 (en) 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
EP3321373B1 (de) 2011-07-13 2020-01-15 T2 Biosystems, Inc. Nmr-verfahren zur überwachung der blutgerinnselbildung
US10620205B2 (en) 2011-09-21 2020-04-14 T2 Biosystems, Inc. NMR methods for endotoxin analysis
WO2013158281A1 (en) 2012-04-20 2013-10-24 T2 Biosystems, Inc. Compositions and methods for detection of candida species
EP2929047A4 (de) 2012-12-07 2016-08-03 T2 Biosystems Inc Verfahren zur überwachung der formierung von dichten gerinnseln
US10309880B2 (en) 2015-03-26 2019-06-04 Dover Photonics Llc Preparation of fluid samples for laser induced breakdown spectroscopy and/or imaging analysis
EP3283879B1 (de) * 2015-04-15 2019-03-27 Attomol GmbH Molekulare Diagnostika Verfahren zum reaktionsraumbegrenzten nachweis von einem oder mehreren analyten in einer probe
WO2017127731A1 (en) 2016-01-21 2017-07-27 T2 Biosystems, Inc. Nmr methods and systems for the rapid detection of bacteria
US20190224671A1 (en) * 2016-03-28 2019-07-25 Tdk Corporation Biosensor and biochip
CN109073597A (zh) * 2016-03-28 2018-12-21 Tdk株式会社 化学传感器
ES2890850T3 (es) 2016-08-26 2022-01-24 Juno Therapeutics Inc Métodos para enumerar partículas presentes en una composición celular
JP6420433B1 (ja) * 2017-09-12 2018-11-07 株式会社 マトリックス細胞研究所 反応促進装置及び反応促進方法
US12140526B2 (en) 2018-02-28 2024-11-12 Juno Therapeutics, Inc. Methods for detecting particles present in a cell composition
JP6370017B1 (ja) * 2018-03-15 2018-08-08 株式会社 マトリックス細胞研究所 反応促進装置及び反応促進方法
JP6370018B1 (ja) * 2018-03-15 2018-08-08 株式会社 マトリックス細胞研究所 反応促進装置及び反応促進方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018886A (en) 1975-07-01 1977-04-19 General Electric Company Diagnostic method and device employing protein-coated magnetic particles
US4230685A (en) 1979-02-28 1980-10-28 Northwestern University Method of magnetic separation of cells and the like, and microspheres for use therein
US4297337A (en) 1979-04-13 1981-10-27 Corning Glass Works Solid-phase immunoassays using magnetic glass
US4375407A (en) * 1981-06-22 1983-03-01 The Franklin Institute High gradient magnetic separation device
US4452773A (en) * 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
NO155316C (no) 1982-04-23 1987-03-11 Sintef Fremgangsmaate for fremstilling av magnetiske polymerpartikler.
US5071774A (en) * 1983-04-05 1991-12-10 Syntex (U.S.A.) Inc. Multiparameter particle analysis
US4554088A (en) 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4795698A (en) 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US4827945A (en) 1986-07-03 1989-05-09 Advanced Magnetics, Incorporated Biologically degradable superparamagnetic materials for use in clinical applications
ATE108556T1 (de) 1987-11-16 1994-07-15 Gene Trak Systems Magnetische trennvorrichtung und verfahren zur anwendung in heterogenen prüfungen.
ES2067018T3 (es) 1988-12-28 1995-03-16 Stefan Miltenyi Procedimiento y materiales para la separacion en alto gradiente magnetico de materiales biologicos.
FR2645160B1 (de) 1989-03-31 1992-10-02 Rhone Poulenc Chimie
US5698271A (en) * 1989-08-22 1997-12-16 Immunivest Corporation Methods for the manufacture of magnetically responsive particles
FR2652163B1 (fr) 1989-09-20 1994-04-15 Bio Merieux Procede de detection d'une substance biologique a l'aide de ligands.
DE4036288A1 (de) * 1989-11-15 1991-05-23 Hitachi Ltd Verfahren und vorrichtung fuer immunologische tests unter nutzung messbarer teilchen
JPH04102062A (ja) * 1990-08-22 1992-04-03 Hitachi Ltd 粒子免疫側定法
US5169754A (en) 1990-10-31 1992-12-08 Coulter Corporation Biodegradable particle coatings having a protein covalently immobilized by means of a crosslinking agent and processes for making same
US5646001A (en) * 1991-03-25 1997-07-08 Immunivest Corporation Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof
US5186827A (en) 1991-03-25 1993-02-16 Immunicon Corporation Apparatus for magnetic separation featuring external magnetic means
FR2679255B1 (fr) * 1991-07-17 1993-10-22 Bio Merieux Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation.
FR2679660B1 (fr) * 1991-07-22 1993-11-12 Pasteur Diagnostics Procede et dispositif magnetique d'analyse immunologique sur phase solide.
WO1993022058A1 (en) * 1992-05-01 1993-11-11 Trustees Of The University Of Pennsylvania Polynucleotide amplification analysis using a microfabricated device
EP0585868B1 (de) 1992-08-31 2000-03-01 Fujirebio Inc. Magnetisches Teilchen und seine Verwendung in einem Immunotest
FR2707010B1 (de) * 1993-06-25 1995-09-29 Bio Merieux
FR2710075B1 (fr) * 1993-09-15 1995-10-27 Bio Merieux Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal.
FR2710410B1 (fr) * 1993-09-20 1995-10-20 Bio Merieux Procédé et dispositif pour la détermination d'un analyte dans un échantillon .
JP3115501B2 (ja) * 1994-06-15 2000-12-11 プレシジョン・システム・サイエンス株式会社 分注機を利用した磁性体の脱着制御方法及びこの方法によって処理される各種装置
JPH10507632A (ja) * 1994-09-20 1998-07-28 ミルテニー バイオテック，インコーポレイティド 母体からの胎児血液の濃縮
US5655665A (en) 1994-12-09 1997-08-12 Georgia Tech Research Corporation Fully integrated micromachined magnetic particle manipulator and separator
JP3962789B2 (ja) 1995-02-21 2007-08-22 ダブリュー． シディキー，イクバール 磁性粒子を利用した混合／分離装置及びその方法
US5705059A (en) 1995-02-27 1998-01-06 Miltenyi; Stefan Magnetic separation apparatus
FR2732116B1 (fr) * 1995-03-21 1997-05-09 Bio Merieux Procede et dispositif pour la determination qualitative et/ou quantitative d'un analyte, notamment d'une bacterie, dans un echantillon, par voie magnetique
US5660990A (en) * 1995-08-18 1997-08-26 Immunivest Corporation Surface immobilization of magnetically collected materials
FR2740222B1 (fr) * 1995-10-23 1997-11-14 Bio Merieux Ensemble de traitement d'un echantillon en milieu liquide, notamment d'un materiel biologique

Also Published As

Publication number Publication date
JP4053092B2 (ja) 2008-02-27
WO1998034116A1 (fr) 1998-08-06
FR2758884A1 (fr) 1998-07-31
CA2280187A1 (fr) 1998-08-06
EP0965045B1 (de) 2002-01-09
AU6104598A (en) 1998-08-25
US6342396B1 (en) 2002-01-29
FR2758884B1 (fr) 1999-04-02
DE69803443T2 (de) 2002-09-05
DE69803443D1 (de) 2002-02-28
EP0965045A1 (de) 1999-12-22
JP2001510565A (ja) 2001-07-31

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