DK0820522T3 - Assays og indretninger til detektering af ekstrahepatisk galdeatresi - Google Patents

Assays og indretninger til detektering af ekstrahepatisk galdeatresi

Info

Publication number
DK0820522T3
DK0820522T3 DK95932298T DK95932298T DK0820522T3 DK 0820522 T3 DK0820522 T3 DK 0820522T3 DK 95932298 T DK95932298 T DK 95932298T DK 95932298 T DK95932298 T DK 95932298T DK 0820522 T3 DK0820522 T3 DK 0820522T3
Authority
DK
Denmark
Prior art keywords
devices
biliary atresia
extrahepatic biliary
assays
detecting
Prior art date
Application number
DK95932298T
Other languages
English (en)
Inventor
Laszlo Takacs
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DK0820522T3 publication Critical patent/DK0820522T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10Anilides
    • C12Q2337/12Para-Nitroanilides p-NA
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK95932298T 1994-07-14 1995-07-13 Assays og indretninger til detektering af ekstrahepatisk galdeatresi DK0820522T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/275,887 US5601986A (en) 1994-07-14 1994-07-14 Assays and devices for the detection of extrahepatic biliary atresia
PCT/US1995/008898 WO1996002667A1 (en) 1994-07-14 1995-07-13 Assays and devices for the detection of extrahepatic biliary atresia

Publications (1)

Publication Number Publication Date
DK0820522T3 true DK0820522T3 (da) 2001-11-19

Family

ID=23054238

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95932298T DK0820522T3 (da) 1994-07-14 1995-07-13 Assays og indretninger til detektering af ekstrahepatisk galdeatresi

Country Status (10)

Country Link
US (1) US5601986A (da)
EP (1) EP0820522B1 (da)
AT (1) ATE205884T1 (da)
AU (1) AU3538195A (da)
CA (1) CA2187783C (da)
DE (1) DE69522831T2 (da)
DK (1) DK0820522T3 (da)
ES (1) ES2160714T3 (da)
PT (1) PT820522E (da)
WO (1) WO1996002667A1 (da)

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US20020086399A1 (en) * 1996-02-29 2002-07-04 Fuji Photo Film Co., Ltd. Method of measurement of protease and thin membranes used for said method
US6235493B1 (en) * 1997-08-06 2001-05-22 The Regents Of The University Of California Amino acid substituted-cresyl violet, synthetic fluorogenic substrates for the analysis of agents in individual in vivo cells or tissue
KR20050122220A (ko) * 2003-03-25 2005-12-28 다케다 샌디에고, 인코포레이티드 디펩티딜 펩티다제 억제제
EP1625122A1 (en) 2003-05-14 2006-02-15 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
KR20060041309A (ko) * 2003-08-13 2006-05-11 다케다 야쿠힌 고교 가부시키가이샤 4-피리미돈 유도체 및 펩티딜 펩티다제 저해제로서의 그의용도
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7678909B1 (en) 2003-08-13 2010-03-16 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP1697342A2 (en) * 2003-09-08 2006-09-06 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7790734B2 (en) * 2003-09-08 2010-09-07 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EA013427B1 (ru) * 2004-03-15 2010-04-30 Такеда Фармасьютикал Компани Лимитед Ингибиторы дипептидилпептидазы
JP2008501714A (ja) * 2004-06-04 2008-01-24 武田薬品工業株式会社 ジペプチジルペプチダーゼインヒビター
WO2006019965A2 (en) 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
US20060019406A1 (en) * 2004-07-23 2006-01-26 Ning Wei Lateral flow device for the detection of large pathogens
US20060068500A1 (en) * 2004-09-28 2006-03-30 Kimberly-Clark Worldwide, Inc. Detecting yeast infections using a lateral flow assay
EP1828192B1 (en) * 2004-12-21 2014-12-03 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US8506934B2 (en) 2005-04-29 2013-08-13 Robert I. Henkin Methods for detection of biological substances
PT1942898E (pt) * 2005-09-14 2011-12-20 Takeda Pharmaceutical Inibidores da dipeptidilpeptidase para o tratamento da diabetes
PE20070622A1 (es) * 2005-09-14 2007-08-22 Takeda Pharmaceutical Administracion de inhibidores de dipeptidil peptidasa
GEP20135791B (en) * 2005-09-14 2013-03-25 Takeda Pharmaceutical Use of dipeptidyl peptidase inhibitors
CN101360723A (zh) * 2005-09-16 2009-02-04 武田药品工业株式会社 制备嘧啶二酮衍生物的方法
TW200745079A (en) * 2005-09-16 2007-12-16 Takeda Pharmaceuticals Co Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
TW200745080A (en) * 2005-09-16 2007-12-16 Takeda Pharmaceuticals Co Polymorphs of tartrate salt of 2-[2-(3-(R)-amino-piperidin-1-yl)-5-fluoro-6-oxo-6H-pyrimidin-1-ylmethyl]-benzonitrile and methods of use therefor
GB2435512A (en) * 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
GB2435511A (en) * 2006-02-23 2007-08-29 Mologic Ltd Protease detection
GB2435510A (en) * 2006-02-23 2007-08-29 Mologic Ltd Enzyme detection product and methods
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP1999108A1 (en) * 2006-03-28 2008-12-10 Takeda Pharmaceutical Company Limited Preparation of (r)-3-aminopiperidine dihydrochloride
GB0606822D0 (en) 2006-04-05 2006-05-17 Alaska Food Diagnostics Assay System
GB2437311A (en) * 2006-04-07 2007-10-24 Mologic Ltd A protease detection product
BRPI0716971A2 (pt) * 2006-09-13 2013-10-15 Takeda Pharmaceutical Uso de 2-6(3-amino-piperini-l-il)-3-metil-2,4-dioxo-3,4-dihidro-2 h-pirimidin-1ilmetil-4-fluoro-benxonitrila
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) * 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US8293489B2 (en) 2007-01-31 2012-10-23 Henkin Robert I Methods for detection of biological substances
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
US8580801B2 (en) 2008-07-23 2013-11-12 Robert I. Henkin Phosphodiesterase inhibitor treatment
CN102818866B (zh) * 2012-08-03 2014-01-22 上海交通大学医学院附属新华医院 用于新生儿胆道闭锁的诊断标记物的应用
EP3108245B1 (en) 2014-02-18 2020-07-22 Robert I. Henkin Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
WO2017009214A1 (en) * 2015-07-10 2017-01-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Early and non invasive method for assessing a subject's risk of having a papillon-lefevre syndrome
MY200300A (en) 2016-04-21 2023-12-19 4TEEN4 Pharmaceuticals GmbH Methods for determining dpp3 and therapeutic methods
CN115243709A (zh) 2020-02-26 2022-10-25 Pam治疗诊断有限公司 肽酰甘氨酸α-酰胺化单加氧酶(PAM)用于治疗目的的用途
WO2021170752A1 (en) 2020-02-26 2021-09-02 Pam Theragnostics Gmbh Methods for determining peptidylglycine alpha-amidating monooxygenase (pam) and its use for diagnostic purpose
JP2023554407A (ja) * 2020-12-18 2023-12-27 深▲じぇん▼市▲絵▼云生物科技有限公司 新生児胆道閉鎖症のバイオマーカーの使用及び検出方法
CN117288962A (zh) * 2023-10-09 2023-12-26 广州市妇女儿童医疗中心 检测标志物组合的试剂在制备胆道闭锁诊断产品中的应用

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US4191809A (en) * 1977-02-26 1980-03-04 Ajinomoto Co., Inc. Method of measuring enzymatic activity using novel peptide derivatives
US4361537A (en) * 1979-01-12 1982-11-30 Thyroid Diagnostics, Inc. Test device and method for its use
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays
US5122602A (en) * 1989-02-13 1992-06-16 Miles Inc. Chromogenic merocyanine enzyme substrates

Also Published As

Publication number Publication date
DE69522831T2 (de) 2002-04-04
US5601986A (en) 1997-02-11
AU3538195A (en) 1996-02-16
EP0820522B1 (en) 2001-09-19
WO1996002667A1 (en) 1996-02-01
ATE205884T1 (de) 2001-10-15
DE69522831D1 (de) 2001-10-25
ES2160714T3 (es) 2001-11-16
EP0820522A1 (en) 1998-01-28
PT820522E (pt) 2002-02-28
CA2187783C (en) 2000-02-08
CA2187783A1 (en) 1996-02-01

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