ATE205884T1 - Assays und vorrichtungen zum nachweis von extrahepatischer biliäreratresie - Google Patents

Assays und vorrichtungen zum nachweis von extrahepatischer biliäreratresie

Info

Publication number
ATE205884T1
ATE205884T1 AT95932298T AT95932298T ATE205884T1 AT E205884 T1 ATE205884 T1 AT E205884T1 AT 95932298 T AT95932298 T AT 95932298T AT 95932298 T AT95932298 T AT 95932298T AT E205884 T1 ATE205884 T1 AT E205884T1
Authority
AT
Austria
Prior art keywords
devices
extrahepatic
atresia
assay
bilary
Prior art date
Application number
AT95932298T
Other languages
English (en)
Inventor
Laszlo Takacs
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE205884T1 publication Critical patent/ATE205884T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT95932298T 1994-07-14 1995-07-13 Assays und vorrichtungen zum nachweis von extrahepatischer biliäreratresie ATE205884T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/275,887 US5601986A (en) 1994-07-14 1994-07-14 Assays and devices for the detection of extrahepatic biliary atresia
PCT/US1995/008898 WO1996002667A1 (en) 1994-07-14 1995-07-13 Assays and devices for the detection of extrahepatic biliary atresia

Publications (1)

Publication Number Publication Date
ATE205884T1 true ATE205884T1 (de) 2001-10-15

Family

ID=23054238

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95932298T ATE205884T1 (de) 1994-07-14 1995-07-13 Assays und vorrichtungen zum nachweis von extrahepatischer biliäreratresie

Country Status (10)

Country Link
US (1) US5601986A (de)
EP (1) EP0820522B1 (de)
AT (1) ATE205884T1 (de)
AU (1) AU3538195A (de)
CA (1) CA2187783C (de)
DE (1) DE69522831T2 (de)
DK (1) DK0820522T3 (de)
ES (1) ES2160714T3 (de)
PT (1) PT820522E (de)
WO (1) WO1996002667A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020086399A1 (en) * 1996-02-29 2002-07-04 Fuji Photo Film Co., Ltd. Method of measurement of protease and thin membranes used for said method
US6235493B1 (en) * 1997-08-06 2001-05-22 The Regents Of The University Of California Amino acid substituted-cresyl violet, synthetic fluorogenic substrates for the analysis of agents in individual in vivo cells or tissue
US20040242568A1 (en) * 2003-03-25 2004-12-02 Syrrx, Inc. Dipeptidyl peptidase inhibitors
WO2004103993A1 (en) 2003-05-14 2004-12-02 Syrrx, Inc. Dipeptidyl peptidase inhibitors
US7790736B2 (en) * 2003-08-13 2010-09-07 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7678909B1 (en) 2003-08-13 2010-03-16 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
JP2007513058A (ja) * 2003-09-08 2007-05-24 武田薬品工業株式会社 ジペプチジルぺプチダーゼ阻害剤
US7790734B2 (en) * 2003-09-08 2010-09-07 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
CN102134229B (zh) * 2004-03-15 2020-08-04 武田药品工业株式会社 二肽基肽酶抑制剂
WO2005118555A1 (en) * 2004-06-04 2005-12-15 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2006019965A2 (en) 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
US20060019406A1 (en) * 2004-07-23 2006-01-26 Ning Wei Lateral flow device for the detection of large pathogens
US20060068500A1 (en) * 2004-09-28 2006-03-30 Kimberly-Clark Worldwide, Inc. Detecting yeast infections using a lateral flow assay
WO2006068978A2 (en) * 2004-12-21 2006-06-29 Takeda Pharmaceutial Company Limited Dipeptidyl peptidase inhibitors
US8506934B2 (en) 2005-04-29 2013-08-13 Robert I. Henkin Methods for detection of biological substances
KR101352588B1 (ko) * 2005-09-14 2014-01-17 다케다 야쿠힌 고교 가부시키가이샤 당뇨병 치료용 디펩티딜 펩티다아제 억제제
PL1942898T5 (pl) 2005-09-14 2014-10-31 Takeda Pharmaceuticals Co Inhibitory peptydazy dipeptydylowej do leczenia cukrzycy
US20070060529A1 (en) * 2005-09-14 2007-03-15 Christopher Ronald J Administration of dipeptidyl peptidase inhibitors
CN102675221A (zh) * 2005-09-16 2012-09-19 武田药品工业株式会社 用于制备嘧啶二酮衍生物的方法中的中间体
TW200745079A (en) * 2005-09-16 2007-12-16 Takeda Pharmaceuticals Co Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
TW200745080A (en) * 2005-09-16 2007-12-16 Takeda Pharmaceuticals Co Polymorphs of tartrate salt of 2-[2-(3-(R)-amino-piperidin-1-yl)-5-fluoro-6-oxo-6H-pyrimidin-1-ylmethyl]-benzonitrile and methods of use therefor
GB2435510A (en) 2006-02-23 2007-08-29 Mologic Ltd Enzyme detection product and methods
GB2435511A (en) * 2006-02-23 2007-08-29 Mologic Ltd Protease detection
GB2435512A (en) * 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2007112368A1 (en) * 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Preparation of (r)-3-aminopiperidine dihydrochloride
GB0606822D0 (en) 2006-04-05 2006-05-17 Alaska Food Diagnostics Assay System
GB2437311A (en) * 2006-04-07 2007-10-24 Mologic Ltd A protease detection product
GEP20125701B (en) * 2006-09-13 2012-12-10 Takeda Pharmaceuticals Co Application of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-ylmethyl]-4-fluoro-benzonitrile
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) * 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US8293489B2 (en) 2007-01-31 2012-10-23 Henkin Robert I Methods for detection of biological substances
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
US8580801B2 (en) 2008-07-23 2013-11-12 Robert I. Henkin Phosphodiesterase inhibitor treatment
CN102818866B (zh) * 2012-08-03 2014-01-22 上海交通大学医学院附属新华医院 用于新生儿胆道闭锁的诊断标记物的应用
WO2015126944A1 (en) 2014-02-18 2015-08-27 Henkin Robert I Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
WO2017009214A1 (en) * 2015-07-10 2017-01-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Early and non invasive method for assessing a subject's risk of having a papillon-lefevre syndrome
JP2019520550A (ja) 2016-04-21 2019-07-18 スフィンゴテック セラピューティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｐｐ３の定量方法および治療方法
EP4110372A1 (de) 2020-02-26 2023-01-04 PAM Theragnostics GmbH Verwendung von peptidylglycin-alpha-amidierende monooxygenase (pam) für therapeutische zwecke
US20230097988A1 (en) 2020-02-26 2023-03-30 Pam Theragnostics Gmbh Methods for determining peptidylglycine alpha-amidating monooxygenase (pam) and its use for diagnostic purpose
CN117288962A (zh) * 2023-10-09 2023-12-26 广州市妇女儿童医疗中心 检测标志物组合的试剂在制备胆道闭锁诊断产品中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191808A (en) * 1975-10-30 1980-03-04 Ajinomoto Co., Inc. Method of measuring dipeptidyl-amino-peptidase activity
US4191809A (en) * 1977-02-26 1980-03-04 Ajinomoto Co., Inc. Method of measuring enzymatic activity using novel peptide derivatives
US4361537A (en) * 1979-01-12 1982-11-30 Thyroid Diagnostics, Inc. Test device and method for its use
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays
US5122602A (en) * 1989-02-13 1992-06-16 Miles Inc. Chromogenic merocyanine enzyme substrates

Also Published As

Publication number Publication date
DE69522831D1 (de) 2001-10-25
US5601986A (en) 1997-02-11
ES2160714T3 (es) 2001-11-16
DE69522831T2 (de) 2002-04-04
AU3538195A (en) 1996-02-16
EP0820522B1 (de) 2001-09-19
DK0820522T3 (da) 2001-11-19
CA2187783A1 (en) 1996-02-01
PT820522E (pt) 2002-02-28
EP0820522A1 (de) 1998-01-28
CA2187783C (en) 2000-02-08
WO1996002667A1 (en) 1996-02-01

Similar Documents

Publication Publication Date Title
ATE205884T1 (de) Assays und vorrichtungen zum nachweis von extrahepatischer biliäreratresie
DE69022286D1 (de) Reagenzien, Verfahren und Testsätze zum Nachweis von Amphetaminen durch einen Fluoreszenz-Polarisations-Immunoassay.
DE69836888D1 (de) Verfahren für Fluoreszenzerkennungstest
DK0941468T3 (da) Et-trins-hybridimmunochromatografisk udstyr og fremgangsmåde til anvendelse heraf
ATE217190T1 (de) Test und reagentien zur identifizierung von antiproliferierenden stoffen
DE69530861D1 (de) Vorrichtung zur durchführung eines oder mehrerer kompetitiver immunoassays
BG104275A (en) Method and device for express analysis of tested parameters in biological samples
ATE376187T1 (de) Nachweis von erkrankungen der nieren und behandlung
DE69839149D1 (de) Methode und vorrichtung zum nachweis oder zur quantifizierung von kohlenhydrate enthaltenden verbindungen
ATE423972T1 (de) Vorrichtung und verfahren um gleichzeitig verschiedene antikörper und antigene nachzuweisen in klinischen, nahrungsmittel- und umwelt-proben
ATE160876T1 (de) Verfahren und zusammensetzungen zum nachweis von serumproteasen, insbesondere für aktiviertes protein c
ATE408829T1 (de) Verfahren und assaykits zum nachweis mononuklearer zellphänotypen
ATE466098T1 (de) Kinase- und phosphatasetests
CY1107621T1 (el) Μεθοδος ανιχνευσης αντισωματων σε ενα δειγμα
ES2109802T3 (es) Dispositivo de ensayo y su fabricacion.
PT918991E (pt) Metodo de ensaio
MX9706437A (es) Proceso y compuestos para la deteccion de analitos usando medicion de remanencia y el uso de los mismos.
DE69332084T2 (de) Eine petroleum immuntestmethode und ihre komponenten
PT1190245E (pt) Deteccao de alergenos
PT1222311E (pt) Teste de helicase por electroquimioluminescencia
CY1106705T1 (el) Δοκιμασια για μετρηση ολο-τρανσκοβαλαμινης και φολικου
DE59910326D1 (de) Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
DE69533586D1 (de) Verfahren zum testen eines asialoglycoproteinrezeptors und testreagenz dafür
DE69025008D1 (de) Verfahren für direkte chemische Bindung des D-Dimers aus einer biologischen Probe zwecks Diagnostik und Überwachung von thrombolytischen und hyperkoagulablen Zuständen
ATE347108T1 (de) Zusammensetzungen und verfahren zum bestimmen von aa4rp

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee