ATE127231T1 - Verfahren zur bestimmung eines oder mehrerer analyte durch anwendung verschiedene typen von partikeln, welche durchflusszytometrisch unterschieden sind. - Google Patents
Verfahren zur bestimmung eines oder mehrerer analyte durch anwendung verschiedene typen von partikeln, welche durchflusszytometrisch unterschieden sind.Info
- Publication number
- ATE127231T1 ATE127231T1 AT89905720T AT89905720T ATE127231T1 AT E127231 T1 ATE127231 T1 AT E127231T1 AT 89905720 T AT89905720 T AT 89905720T AT 89905720 T AT89905720 T AT 89905720T AT E127231 T1 ATE127231 T1 AT E127231T1
- Authority
- AT
- Austria
- Prior art keywords
- particles
- analyte
- different
- binding
- flow cytometer
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 238000000684 flow cytometry Methods 0.000 title 1
- 239000012491 analyte Substances 0.000 abstract 4
- 230000027455 binding Effects 0.000 abstract 4
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 108090001008 Avidin Proteins 0.000 abstract 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 102000004856 Lectins Human genes 0.000 abstract 1
- 108090001090 Lectins Proteins 0.000 abstract 1
- 108010090804 Streptavidin Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 229960002685 biotin Drugs 0.000 abstract 1
- 235000020958 biotin Nutrition 0.000 abstract 1
- 239000011616 biotin Substances 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 238000007822 cytometric assay Methods 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 108091008039 hormone receptors Proteins 0.000 abstract 1
- 239000002523 lectin Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO882067A NO164622C (no) | 1988-05-11 | 1988-05-11 | Binaer immunometrisk partikkelbasert metode for maaling av spesifikke serum-antigener ved hjelp av vaeskestroemsmikrofotometri og et ferdigpreparert maaloppsett derav. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE127231T1 true ATE127231T1 (de) | 1995-09-15 |
Family
ID=19890879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89905720T ATE127231T1 (de) | 1988-05-11 | 1989-05-10 | Verfahren zur bestimmung eines oder mehrerer analyte durch anwendung verschiedene typen von partikeln, welche durchflusszytometrisch unterschieden sind. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5585241A (de) |
EP (1) | EP0413741B1 (de) |
JP (1) | JP2742953B2 (de) |
AT (1) | ATE127231T1 (de) |
AU (1) | AU3565889A (de) |
CA (1) | CA1335238C (de) |
DE (1) | DE68924064T2 (de) |
NO (1) | NO164622C (de) |
WO (1) | WO1989011101A1 (de) |
Families Citing this family (114)
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Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3366740D1 (en) * | 1982-08-06 | 1986-11-13 | Int Inst Cellular Molecul Path | Particle agglutination assay of antigens |
US4595661A (en) * | 1983-11-18 | 1986-06-17 | Beckman Instruments, Inc. | Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect |
US4590169A (en) * | 1983-11-18 | 1986-05-20 | Beckman Instruments, Inc. | Direct particle agglutination immunoassays avoiding false negatives at high antigen concentrations |
US4665020A (en) * | 1984-05-30 | 1987-05-12 | United States Department Of Energy | Flow cytometer measurement of binding assays |
JPS60256057A (ja) * | 1984-06-01 | 1985-12-17 | Dai Ichi Pure Chem Co Ltd | 免疫学的測定法 |
JPS61290362A (ja) * | 1985-06-18 | 1986-12-20 | Showa Denko Kk | 微粒子測定法 |
US5047321A (en) * | 1988-06-15 | 1991-09-10 | Becton Dickinson & Co. | Method for analysis of cellular components of a fluid |
-
1988
- 1988-05-11 NO NO882067A patent/NO164622C/no unknown
-
1989
- 1989-05-10 JP JP1505599A patent/JP2742953B2/ja not_active Expired - Fee Related
- 1989-05-10 DE DE68924064T patent/DE68924064T2/de not_active Expired - Fee Related
- 1989-05-10 EP EP89905720A patent/EP0413741B1/de not_active Expired - Lifetime
- 1989-05-10 WO PCT/GB1989/000506 patent/WO1989011101A1/en active IP Right Grant
- 1989-05-10 AT AT89905720T patent/ATE127231T1/de not_active IP Right Cessation
- 1989-05-10 AU AU35658/89A patent/AU3565889A/en not_active Abandoned
- 1989-05-11 CA CA000599225A patent/CA1335238C/en not_active Expired - Fee Related
-
1995
- 1995-06-01 US US08/457,158 patent/US5585241A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE68924064T2 (de) | 1996-02-08 |
JPH03504276A (ja) | 1991-09-19 |
WO1989011101A1 (en) | 1989-11-16 |
NO164622B (no) | 1990-07-16 |
NO882067D0 (no) | 1988-05-11 |
EP0413741B1 (de) | 1995-08-30 |
US5585241A (en) | 1996-12-17 |
CA1335238C (en) | 1995-04-18 |
NO164622C (no) | 1990-10-24 |
DE68924064D1 (de) | 1995-10-05 |
AU3565889A (en) | 1989-11-29 |
NO882067L (no) | 1989-11-13 |
EP0413741A1 (de) | 1991-02-27 |
JP2742953B2 (ja) | 1998-04-22 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |