ATE464283T1 - N-substituierte p-menthancarbonsäureamide - Google Patents

N-substituierte p-menthancarbonsäureamide

Info

Publication number
ATE464283T1
ATE464283T1 AT04761978T AT04761978T ATE464283T1 AT E464283 T1 ATE464283 T1 AT E464283T1 AT 04761978 T AT04761978 T AT 04761978T AT 04761978 T AT04761978 T AT 04761978T AT E464283 T1 ATE464283 T1 AT E464283T1
Authority
AT
Austria
Prior art keywords
menthane
substituted
carbonic acid
acid amides
groups
Prior art date
Application number
AT04761978T
Other languages
English (en)
Inventor
Christophe Galopin
Pablo Krawec
Jay Slack
Lori Tigani
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Sa filed Critical Givaudan Sa
Application granted granted Critical
Publication of ATE464283T1 publication Critical patent/ATE464283T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/61—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
    • C07C255/44—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms at least one of the singly-bound nitrogen atoms being acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24—Thermal properties
    • A61K2800/244—Endothermic; Cooling; Cooling sensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Ceramic Products (AREA)
  • Catalysts (AREA)
AT04761978T 2003-11-21 2004-10-28 N-substituierte p-menthancarbonsäureamide ATE464283T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52397703P 2003-11-21 2003-11-21
PCT/CH2004/000646 WO2005049553A1 (en) 2003-11-21 2004-10-28 N-substituted p-menthane carbosamided

Publications (1)

Publication Number Publication Date
ATE464283T1 true ATE464283T1 (de) 2010-04-15

Family

ID=34619622

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04761978T ATE464283T1 (de) 2003-11-21 2004-10-28 N-substituierte p-menthancarbonsäureamide

Country Status (10)

Country Link
US (2) US7414152B2 (de)
EP (1) EP1685093B3 (de)
JP (1) JP4786544B2 (de)
CN (1) CN100582089C (de)
AT (1) ATE464283T1 (de)
BR (1) BRPI0416770B1 (de)
DE (1) DE602004026619D1 (de)
ES (1) ES2342466T7 (de)
PL (1) PL1685093T6 (de)
WO (1) WO2005049553A1 (de)

Families Citing this family (183)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006017038D1 (de) * 2005-03-01 2010-11-04 Givaudan Sa Menthancarbonsäureamidderivate mit kühlenden eigenschaften
GB0504194D0 (en) * 2005-03-02 2005-04-06 Givaudan Sa Organic compounds
CN101184470A (zh) * 2005-05-27 2008-05-21 吉万奥丹股份有限公司 清凉化合物
US9452982B2 (en) * 2005-08-15 2016-09-27 Givaudan, S.A. Pyridinyl cyclohexanecarboxamide cooling compounds
DE602006009290D1 (de) 2005-10-25 2009-10-29 Givaudan Sa Organische verbindungen
WO2007104175A2 (en) * 2006-03-15 2007-09-20 Givaudan Sa Para-substituted 2-alkoxyphenol compounds
WO2008006236A2 (en) * 2006-07-14 2008-01-17 Givaudan Sa Benzimidazoles as cooling compounds
CN101583287A (zh) * 2006-12-20 2009-11-18 奇华顿荷兰服务有限责任公司 N-取代-对薄荷烷-3-甲酰胺及其用途
GB0704163D0 (en) * 2007-03-02 2007-04-11 Quest Int Serv Bv Compositions comprising a physiological coolant
US7935848B2 (en) 2007-05-23 2011-05-03 Givaudan S.A. Butone derivatives useful as cooling agents
JP2010528631A (ja) 2007-06-06 2010-08-26 ジボダン エス エー 塩味増強
US8655677B2 (en) * 2007-06-12 2014-02-18 Bruce Reiner Productivity workflow index
EP2167024B1 (de) 2007-06-13 2012-01-11 Givaudan SA Verbindungen mit kühlender wirkung
US7880011B2 (en) 2007-07-23 2011-02-01 Givandan, S.A. Amide addition reaction
ES2395682T3 (es) 2007-08-20 2013-02-14 Symrise Ag Derivados de ácido oxálico y su uso como principios activos refrescantes fisiológicos
CN101873845A (zh) * 2007-10-11 2010-10-27 麦克内尔-Ppc股份有限公司 改良的局部镇痛产品
WO2009062332A2 (en) * 2007-11-16 2009-05-22 Givaudan Sa Cooling compounds
US8377422B2 (en) 2007-12-07 2013-02-19 Givaudan S.A. Carboxamide derivatives having cooling properties
WO2009076792A1 (en) 2007-12-19 2009-06-25 Givaudan Sa Cooling compounds
EP2250154A1 (de) * 2008-01-17 2010-11-17 Givaudan SA Benzimidazolderivate und ihre verwendung als kühlmittel
CN102123742A (zh) * 2008-02-22 2011-07-13 宝洁公司 包括含有凉爽剂的洗剂组合物的吸收制品
DE102008015424A1 (de) * 2008-03-20 2009-09-24 Beiersdorf Ag Kühlende kosmetische oder dermatologische Zubereitungen mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridyn-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5- methylcyclohexancarboxamid mit Menthoxypropandiol
DE102008015425A1 (de) * 2008-03-20 2010-01-21 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen zur Verringerung von Juckreiz und anderen dermatologischen Missempfindungen, die insbesondere bei Altershaut auftreten können, mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexancarboxamid
DE102008015428A1 (de) * 2008-03-20 2009-09-24 Beiersdorf Ag Kühlende Zubereitungen für den humanen Haut- und/oder Schleimhautkontakt mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexancarboxamid
DE102008015426A1 (de) * 2008-03-20 2009-09-24 Beiersdorf Ag Kühlende kosmetische oder dermatologische Zubereitungen mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridyn-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexancarboxamid zu Reduktion von Hautrötungen
US20110091531A1 (en) * 2008-05-22 2011-04-21 Giv Audan Sa Cooling Composition
MX2011001724A (es) * 2008-08-15 2011-03-21 Procter & Gamble Sintesis de derivados de ciclohexano utiles como agentes de sensacion en productos de consumo.
WO2010019729A1 (en) * 2008-08-15 2010-02-18 The Procter & Gamble Company Solution of menthane carboxamides for use in consumer products
ES2626230T3 (es) 2008-11-20 2017-07-24 The Procter & Gamble Company Composiciones para la higiene personal que proporcionan una sensación refrescante mejorada
FR2944790B1 (fr) * 2009-04-23 2012-06-01 Mane Fils V Nouveaux composes a effet physiologique
US7923577B2 (en) * 2009-04-27 2011-04-12 International Flavors & Fragrances Inc. Menthylcarboxamides and their use as cooling agents
US8664261B2 (en) 2009-05-05 2014-03-04 Givaudan S.A. Organic compounds having cooling properties
BR112012001599A2 (pt) 2009-07-29 2016-03-08 Unilever Nv composição dentifricia
WO2011012671A1 (en) 2009-07-29 2011-02-03 Givaudan Sa Improvements in or relating to organic compounds
EP2295031B1 (de) 2009-08-05 2018-01-10 Symrise AG Verwendung von Pterocarpanen als Anti-Cellulite-Wirkstoffe
CN102802732B (zh) 2009-09-11 2016-04-27 宝洁公司 用于口腔表面疏水改性的方法和组合物
US20110195042A1 (en) * 2010-02-10 2011-08-11 Thomas Edward Huetter Compositions, Methods and Kits Useful for Treating a Respiratory Symptom
ES2701018T3 (es) 2010-04-01 2019-02-20 Procter & Gamble Control del mal olor de toda la boca mediante una combinación de agentes antibacterianos y desodorantes
WO2010070152A2 (en) 2010-04-08 2010-06-24 Symrise Gmbh & Co. Kg Use of dihydrodehydrodiisoeugenol and preparations comprising dihydrodehydrodiisoeugenol
EP2389922A1 (de) 2010-05-25 2011-11-30 Symrise AG Cyclohexylcarbamatverbindungen als Anti-ageing-Wirkstoffe
EP2595642A2 (de) 2010-07-19 2013-05-29 The Procter and Gamble Company Zusammensetzungen mit derivaten aus ätherischen ölverbindungen und verwendung für körperpflegeprodukte
US20130216648A1 (en) 2010-09-09 2013-08-22 Kraft Foods Global Brands Llc Chewing gum compositions providing flavor release profiles
US9937115B2 (en) 2010-10-01 2018-04-10 The Procter & Gamble Company Oral care compositions with improved flavor
US20120116113A1 (en) 2010-11-05 2012-05-10 Erman Mark B PROCESS FOR MAKING NEO-ENRICHED p-MENTHANE COMPOUNDS
EP2286908A3 (de) 2010-11-19 2011-06-01 Symrise AG Lösungsvermittler für kosmetische Zubereitungen
EP2356977B1 (de) 2011-02-02 2017-12-27 Symrise AG Zubereitungen mit Holzextrakten von Gleditschien
US9421171B2 (en) 2011-02-14 2016-08-23 The Procter & Gamble Company Coated solid dosage forms
GB201103103D0 (en) * 2011-02-23 2011-04-06 Givaudan Sa Organic compounds
US9023776B2 (en) * 2011-07-26 2015-05-05 Givaudan S.A. Rinse-off compositions comprising lactoyl ethanolamine and a menthanecarboxamide compound
US20130042482A1 (en) 2011-08-16 2013-02-21 Valerie Jean Bradford Skin Engaging Member Comprising An Anti-Irritation Agent
US9802885B2 (en) 2011-09-01 2017-10-31 Takasago International Corporation (Usa) Substituted cyclohexane compounds
MX344234B (es) 2011-09-01 2016-12-01 Procter & Gamble Composiciones para el cuidado bucal con reologia mejorada.
GB201205444D0 (en) 2012-03-28 2012-05-09 Givaudan Sa Composition
WO2013174615A2 (en) * 2012-05-22 2013-11-28 Unilever N.V. Personal care composition
US20130315843A1 (en) 2012-05-25 2013-11-28 The Procter & Gamble Company Composition for reduction of trpa1 and trpv1 sensations
BR112014031168B1 (pt) 2012-06-15 2018-05-02 Symrise Ag Método não terapêutico para a estimulação da biossíntese de hialuronana, composição farmacêutica ou dermatológica, e uso da mesma
US10123953B2 (en) 2012-06-21 2018-11-13 The Procter & Gamble Company Reduction of tooth staining derived from cationic antimicrobials
US20130344120A1 (en) 2012-06-21 2013-12-26 Douglas Craig Scott Mouth Rinse Emulsions
HK1203771A1 (en) 2012-07-02 2015-11-06 Symrise Ag A method of flavouring a smoking product
EP3552597A1 (de) 2012-08-07 2019-10-16 Symrise AG Compositions cosmétiques
WO2014052390A2 (en) 2012-09-28 2014-04-03 The Gillette Company A skin engaging member comprising at least one thermally resilient sensate
US20140090255A1 (en) * 2012-09-28 2014-04-03 The Gillette Company Skin Engaging Member Comprising At Least One Thermally Resilient Sensate
SG11201501482SA (en) * 2012-09-28 2015-03-30 Gillette Co A skin engaging shaving aid member comprising at least one thermally resilient sensate
EP2745878B1 (de) 2012-12-19 2023-01-25 Symrise AG Kosmetische Zubereitungen
JP6408489B2 (ja) 2013-01-25 2018-10-17 ウィンターミュート バイオメディカル、インコーポレイテッド 治療配合物（ｃｏｍｐｏｕｎｄｓ）
EP2764860A1 (de) 2013-02-06 2014-08-13 Basf Sa Cupuassufettsäureamidoamine und ihre Derivate
PL2956120T3 (pl) 2013-02-13 2020-08-10 The Procter & Gamble Company Leki o smaku anyżu
ES2701758T3 (es) 2013-02-27 2019-02-25 Symrise Ag Extracto de jengibre para la protección de citoblastos
PL2774481T3 (pl) 2013-03-08 2019-03-29 Symrise Ag Kompozycje przeciwdrobnoustrojowe
ES2647784T3 (es) 2013-03-08 2017-12-26 Symrise Ag Composiciones cosméticas
EP2783578A1 (de) 2013-03-26 2014-10-01 Symrise AG Catechin Reaktionsprodukte
EP2789369B1 (de) 2013-04-14 2018-06-06 Symrise AG Eine Zubereitung zur Aufhellung von Haut und Haaren
EP2807925A1 (de) 2013-05-26 2014-12-03 Symrise AG Antimikrobielle Zusammensetzungen
EP2810934A1 (de) 2013-06-09 2014-12-10 Symrise AG Neue Succinatderivate
CN105307625B (zh) 2013-06-24 2018-10-23 宝洁公司 防污口腔护理组合物
EP2842607B1 (de) 2013-09-02 2018-05-30 Symrise AG Eine Mischung zur Aufhellung von Haut und/oder Haaren
WO2015040010A1 (en) 2013-09-22 2015-03-26 Cutech Srl Extracts fo halimione portulacoides and their application
EP2853254B1 (de) 2013-09-26 2017-11-08 Symrise AG Kosmetische Zusammensetzung zur Aufhellung von Haut und/oder Haaren
EP2859883B1 (de) 2013-10-13 2019-05-15 Symrise AG Mischungen von Aktivstoffen enthaltend acylierte Oligopeptide und Troxerutin
EP2862852B1 (de) 2013-10-18 2018-07-04 Symrise AG Harnstoffderivate für den Schutz von Stammzellen
US20160250121A1 (en) 2013-10-29 2016-09-01 Paolo Pertile Use of mono ornithine ketoglutarate (mokg)
US9884130B2 (en) 2013-11-13 2018-02-06 The Procter & Gamble Company Compositions for delivery of oral comfort sensations
AU2015222884A1 (en) 2014-02-27 2016-08-04 The Procter & Gamble Company Oral care compositions with a reduced bitter taste perception
ES2643590T3 (es) 2014-03-18 2017-11-23 Symrise Ag Dióxido de titanio revestido para reducir el efecto de blanqueamiento en la piel
US20150273711A1 (en) * 2014-03-26 2015-10-01 The Gillette Company Razor Comprising A Molded Shaving Aid Composition Comprising A Thermally Resilient Sensate
US20150272847A1 (en) * 2014-03-26 2015-10-01 The Gillette Company Skin Engaging Shaving Aid Comprising A Thermally Resilient Sensate And A TRPA1 Receptor Inhibitor
AU2015249706A1 (en) 2014-04-23 2016-11-03 The Procter & Gamble Company Cyclohexanecarboxamide with cooling properties
EP2962678A1 (de) 2014-06-30 2016-01-06 Symrise AG Aroma- und Duftstoffzubereitungen enthaltend Acetophenon-Derivate
EP3443950A1 (de) 2014-07-30 2019-02-20 Symrise AG Prafümzubereitung
CN114191317A (zh) 2014-08-15 2022-03-18 宝洁公司 感官体验增强的口腔护理组合物
AU2015301965B2 (en) 2014-08-15 2018-10-04 The Procter & Gamble Company Oral care compositions and regimens
JP2017523218A (ja) 2014-08-15 2017-08-17 ザ プロクター アンド ギャンブル カンパニー 漸増式薬品を有する歯磨剤
EP3023090B1 (de) 2014-11-21 2019-08-07 Symrise AG Zubereitungen
AU2015353904B2 (en) 2014-11-26 2018-12-20 The Gillette Company Llc A skin engaging member comprising ethylene vinyl acetate
EP3233020B1 (de) 2014-12-18 2020-05-06 The Gillette Company LLC Gleitmittelstreifen für rasierklingeneinheiten
MX2017008210A (es) 2014-12-18 2017-10-06 Gillette Co Llc Elementos lubricantes que tienen componentes hidrofobos para cartuchos de rasuradora.
EP3045161A1 (de) 2015-01-18 2016-07-20 Symrise AG Aktive Zusammensetzung enthaltend 1,2-Hexandiol und 1,2-Octandiol
US9951295B2 (en) 2015-02-19 2018-04-24 The Procter & Gamble Company Compositions for deposition on biological surfaces
CN107532063B (zh) * 2015-03-25 2020-03-10 高砂香料工业株式会社 甲基薄荷醇衍生物和含有其的冷感剂组合物
US9993410B2 (en) 2015-04-09 2018-06-12 The Procter & Gamble Company Reduction in CPC taste aversion by reducing CPC activation of TRPA1, TPRV1, or both
EP3081207B1 (de) 2015-04-16 2022-09-21 Symrise AG Verwendung einer liposomenzusammensetzung
US10391071B2 (en) 2015-04-28 2019-08-27 Cutech Srl Compositions comprising valerian extracts
EP3097905B1 (de) 2015-05-28 2020-11-04 Symrise AG Kosmetische zubereitungen
JP6838047B2 (ja) 2015-09-08 2021-03-03 シムライズ アーゲー 香料混合物
CA3000021C (en) 2015-10-22 2020-10-13 The Procter & Gamble Company Method of separating stereoisomers using supercritical fluid chromatography
AU2016342264A1 (en) 2015-10-22 2018-04-05 The Procter & Gamble Company Synthesis of cyclohexane carboxamide derivatives useful as sensates in consumer products
US10639251B2 (en) 2015-10-28 2020-05-05 Symrise Ag Method for inhibiting or masking fishy odours
CN108472220B (zh) 2015-11-15 2022-06-17 西姆莱斯股份公司 减少皮肤刺痛感受
WO2017097434A1 (en) 2015-12-06 2017-06-15 Symrise Ag A fragrance composition
BR112018011372B1 (pt) 2015-12-10 2021-05-04 Symrise Ag Uso de [6] paradol para estabilizar o sabor e/ou odor, método para estabilizar o sabor e/ou odor
US11540987B2 (en) 2015-12-16 2023-01-03 Symrise Ag Composition with stabilized taste and odor (II)
CN108368035A (zh) 2015-12-18 2018-08-03 宝洁公司 在消费品中可用作感觉剂的环己烷酯衍生物的合成
EP3090726B1 (de) 2015-12-21 2019-05-29 Thiocyn GmbH Kosmetische zusammensetzung mit einer kombination von wirkstoffen
ES2730087T3 (es) 2016-01-13 2019-11-08 Thiocyn Gmbh Composición para el crecimiento del cabello
KR20180124121A (ko) 2016-03-30 2018-11-20 시므라이즈 아게 활성 혼합물
MX371216B (es) 2016-04-01 2020-01-08 Procter & Gamble Composiciones para el cuidado bucal que contienen redes de gel y nitrato de potasio.
EP3435965B1 (de) 2016-04-01 2020-07-29 The Procter and Gamble Company Mundfplegemittel mit einer effektiven duftdarstellung
BR112018069979A2 (pt) 2016-04-01 2019-02-05 Procter & Gamble composições para tratamento bucal contendo nitrato de potássio e peróxido
US20170334082A1 (en) 2016-05-18 2017-11-23 The Gillette Company Llc Skin Engaging Member Comprising Ethylene Vinyl Acetate
EP3463580B1 (de) 2016-05-23 2020-03-25 Symrise AG Ein weizenkleie extrakt in einer haarpflegemischung
EP4603149A3 (de) 2016-08-20 2025-12-24 Symrise AG Konservierende mischung
JP6828136B2 (ja) 2016-10-11 2021-02-10 シムライズ アーゲー 抗菌組成物
CA3037589C (en) 2016-10-25 2022-01-04 The Procter & Gamble Company Creped fibrous structures
CA3036897C (en) 2016-10-25 2021-11-16 The Procter & Gamble Company Fibrous structures
WO2018085479A1 (en) 2016-11-03 2018-05-11 The Gillette Company Llc Skin engaging member comprising ethylene vinyl acetate
EP3541476A1 (de) 2016-11-17 2019-09-25 The Gillette Company LLC Hauteingriffselement mit ethylenvinylacetat und einem duftstoff
EP4483953A3 (de) 2016-12-02 2025-03-19 Symrise AG Kosmetische mischungen
ES2922649T3 (es) 2017-01-10 2022-09-19 Takasago Perfumery Co Ltd Derivado de metilmentol y composición que confiere sensación de frescor que contiene el mismo
AU2018217906A1 (en) 2017-02-13 2019-08-15 Wintermute Biomedical, Inc. Anti-pathogenic therapeutic compositions
IT201700090929A1 (it) 2017-08-07 2019-02-07 Cutech S R L Usi cosmetici e medici di estratti del fungo Coprinus comatus per la regolazione dell’unità pilo sebacea.
DE202017007679U1 (de) 2017-08-09 2024-03-15 Symrise Ag 1,2-Alkandiole
WO2019029808A1 (en) 2017-08-09 2019-02-14 Symrise Ag 1,2-ALKANEDIOLS AND PROCESSES FOR PRODUCING THE SAME
WO2019037844A1 (en) 2017-08-23 2019-02-28 Symrise Ag NOVEL NATURAL BUTTER COMPOSITIONS AND USES THEREOF
EP3672691B1 (de) 2017-08-23 2023-06-28 Symrise AG Verwendungen von ischrysis sp extrakten
BR112020006732B1 (pt) 2017-10-10 2022-08-23 Symrise Ag Composições contendo derivados de ácido benzoico ou ácido furoico e uso dos derivados para a estabilidade de emulsão e espuma
CN111212884A (zh) * 2017-10-16 2020-05-29 高砂香料工业株式会社 含有2,2,6-三甲基环己烷羧酸衍生物的冷感剂组合物
CN111132558A (zh) 2017-10-23 2020-05-08 西姆莱斯有限公司 芳香组合物
JP6981243B2 (ja) * 2017-12-27 2021-12-15 ライオン株式会社 歯磨剤組成物
US12016944B2 (en) 2018-03-08 2024-06-25 Symrise Ag Mixtures comprising a protein extract for the treatment of human skin and/or hair
CA3099310C (en) 2018-05-28 2024-03-05 The Procter & Gamble Company Oral care composition with improved deposition efficacy of a cooling sensate agent in the oral cavity
WO2020015816A1 (de) 2018-07-16 2020-01-23 Symrise Ag Zusammensetzung zur substitution von zucker in backwaren
KR20210049850A (ko) 2018-08-27 2021-05-06 시므라이즈 아게 적어도 하나의 하이드록시페논 유도체 (hydroxyphenone derivative) 를 포함하는 항균성 혼합물
KR102698153B1 (ko) 2018-09-14 2024-08-22 시므라이즈 아게 헤어 케어 조성물
KR102837846B1 (ko) 2018-09-20 2025-07-23 시므라이즈 아게 무취 1,2-펜탄디올을 포함하는 조성물
JP7608342B2 (ja) 2018-10-01 2025-01-06 ウィンターミュート バイオメディカル，インク． 治療用組成物
WO2020069762A1 (en) 2018-10-05 2020-04-09 Symrise Ag A method for fighting female body odors
JP2020070263A (ja) * 2018-11-01 2020-05-07 ライオン株式会社 液体口腔用組成物
MX2021004942A (es) 2018-11-02 2021-06-08 Symrise Ag Una mezcla liquida y transparente de filtros de uv.
MX2021005418A (es) 2018-11-08 2021-07-06 Symrise Ag Una composicion a base de agente tensioactivo antimicrobiano.
KR102817868B1 (ko) 2019-01-17 2025-06-05 시므라이즈 아게 항균 혼합물
WO2020147977A1 (de) 2019-01-18 2020-07-23 Symrise Ag Kombinationsmittel
EP3938054A1 (de) 2019-03-11 2022-01-19 Symrise AG Verfahren zur verbesserung der leistung eines duftstoffes oder eines duftstoffgemisches
WO2020182318A1 (en) 2019-03-12 2020-09-17 Symrise Ag An antimicrobial mixture
MX2021011386A (es) 2019-03-22 2021-10-13 Symrise Ag Peptidos de plantas y sus aplicaciones (ii).
WO2020192865A1 (en) 2019-03-22 2020-10-01 Symrise Ag Plant peptides and their applications
CN113747948B (zh) 2019-04-26 2023-12-15 宝洁公司 减少来源于阳离子抗微生物剂的牙齿变色
WO2020249216A1 (en) 2019-06-13 2020-12-17 Symrise Ag A cooling preparation
US20220354772A1 (en) 2019-07-02 2022-11-10 Symrise Ag Blend of beeswax and a lactylate ester
JP7706442B2 (ja) 2019-09-04 2025-07-11 シムライズ アーゲー 香油混合物
CN114727914A (zh) 2019-10-16 2022-07-08 西姆莱斯股份公司 用于将化妆品活性物质间接转移至皮肤的制品
EP4149419A1 (de) 2020-05-11 2023-03-22 Symrise AG Feste mucoadhäsive zusammensetzung
WO2021228352A1 (en) 2020-05-11 2021-11-18 Symrise Ag A fragrance composition
WO2022067142A1 (en) 2020-09-28 2022-03-31 The Procter & Gamble Company Oral care composition comprising hops and flavor
WO2022111793A1 (en) 2020-11-24 2022-06-02 Symrise Ag Medicament for accelerated wound healing
WO2022111829A1 (en) 2020-11-30 2022-06-02 Symrise Ag Essential oils of citrus fruits for use as medicament for induced, increased and/or accelerated autophagy in human keratinocytes
WO2022122122A1 (en) 2020-12-08 2022-06-16 Symrise Ag Medicament for fighting inflammatory conditions of human skin (i)
ES3020332T3 (en) 2020-12-09 2025-05-22 Symrise Ag A mixture comprising 1,2-alkanediols
WO2022122134A1 (en) 2020-12-09 2022-06-16 Symrise Ag Compositions with (bio)-alkanediols and cooling agents
WO2022122167A1 (en) 2020-12-11 2022-06-16 Symrise Ag Medicament for preventing or treating pathologic conditions of human skin (i)
WO2022128051A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for fighting inflammatory conditions of human skin (ii)
WO2022128054A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for fighting inflammatory conditions of human skin (iv)
WO2022128048A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for preventing or treating pathologic conditions of human skin
WO2022128057A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for prevention and treatment of collagen degradation in human connecting tissue
WO2022128052A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for fighting inflammatory conditions of human skin
WO2022128050A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for fighting inflammation and pain
WO2022161593A1 (en) 2021-01-26 2022-08-04 Symrise Ag Medicament for accelerated wound healing
KR20230145150A (ko) 2021-02-12 2023-10-17 시므라이즈 아게 과색소 침착의 예방 및 치료를 위한 약제 (medicament)
WO2022214187A1 (en) 2021-04-08 2022-10-13 Symrise Ag An o/w emulsion base and emulsions comprising the same
EP4322911A1 (de) 2021-04-13 2024-02-21 Symrise AG Isocitronellol enthaltendes riechstoffgemisch
WO2022223099A1 (en) 2021-04-19 2022-10-27 Symrise Ag Compositions comprising cannabidiol and, optionally, bisabolol
EP4083050A1 (de) 2021-05-01 2022-11-02 Analyticon Discovery GmbH Mikrobielle glykolipide
CA3219441A1 (en) 2021-05-11 2022-11-17 The Procter & Gamble Company Oral care compositions comprising block copolymer
GB202303792D0 (en) 2023-03-15 2023-04-26 Givaudan Sa Cosmetic composition

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150052A (en) * 1971-02-04 1979-04-17 Wilkinson Sword Limited N-substituted paramenthane carboxamides
GB1351761A (en) * 1971-02-04 1974-05-01 Wilkinson Sword Ltd Substituted p-menthane carboxamides and compositions containing them
US4136163A (en) * 1971-02-04 1979-01-23 Wilkinson Sword Limited P-menthane carboxamides having a physiological cooling effect
GB1353381A (en) 1971-02-04 1974-05-15 Wilkinson Sword Ltd Substituted p-menthanes and compositions containing them
PH10359A (en) 1971-02-04 1977-01-05 Wilkinson Sword Ltd N-substituted-p-methane-3-carboxamides having physiological cooling activity and compositions containing them
GB1351762A (en) 1971-02-14 1974-05-01 Wilkinson Sword Ltd Tobacco and tobacco-containing manufactures
GB1421744A (en) 1972-04-18 1976-01-21 Wilkinson Sword Ltd Aliphatic n-substituted tertiary amides possessing physiological cooling activity
US4296093A (en) 1973-04-16 1981-10-20 Wilkinson Sword Limited Cyclic carboxamides having a physiological cooling effect
GB1471894A (en) 1973-12-12 1977-04-27 Wilkinson Sword Ltd Compositions for application to or consumption by the body and containing a compound having a physiological cooling effect
GB1457671A (en) * 1974-01-31 1976-12-08 Wilkinson Sword Ltd Flavour
JPH07506868A (ja) * 1992-05-18 1995-07-27 ザ、プロクター、エンド、ギャンブル、カンパニー 冷却剤組成物
US6399614B1 (en) 1997-08-01 2002-06-04 Recordati S.A. Chemical And Pharmaceutical Company 1-(N-phenylaminoalkyl)piperazine derivatives substituted at position 2 of the phenyl ring
BRPI0113421B8 (pt) * 2000-08-24 2016-05-10 Givaudan Sa uso de compostos p-mentano carboxamidas n-substituídas como repelente de insetos
US6348625B1 (en) 2000-11-10 2002-02-19 Gloria Long Anderson Method for preparing some 1-adamantancecarboxamides
CN1300095C (zh) 2002-10-28 2007-02-14 吉万奥丹股份有限公司 清凉剂溶液及含有其的组合物
JP2006522750A (ja) 2003-04-11 2006-10-05 ノボ　ノルディスク　アクティーゼルスカブ 代謝性症候群ならびに関連の疾患および障害を治療するために、１１β−ヒドロキシステロイドデヒドロゲナーゼ１型阻害剤および抗高血圧剤を使用する併用療法
CN1845741A (zh) * 2003-07-02 2006-10-11 健泰科生物技术公司 Trp－p8活性化合物和治病性治疗方法
CA2530884C (en) * 2003-07-02 2016-01-12 Genentech, Inc. Trp-p8 active compounds and therapeutic treatment methods
JP5036310B2 (ja) 2003-08-06 2012-09-26 セノミックス インコーポレイテッド 新規な風味、風味改質剤、味覚剤、味覚向上剤、旨味および甘味味覚剤、および／またはそれらの向上剤および使用
WO2005020897A2 (en) 2003-08-22 2005-03-10 Dendreon Corporation Compositions and methods for the treatment of disease associated with trp-p8 expression
US7169377B2 (en) * 2003-10-15 2007-01-30 Wei Edward T Radioligands for the TRP-M8 receptor and methods therewith
WO2005048965A2 (en) 2003-11-13 2005-06-02 Wm. Wrigley Jr. Company Method and composition for breath freshening
US7417048B2 (en) 2003-12-31 2008-08-26 Wei Edward T Aryl-substituted derivatives of cycloalkyl and branched chain alkyl carboxylic acids useful as antinociceptive drugs for peripheral targets
US20050187211A1 (en) 2004-02-23 2005-08-25 Wei Edward T. N-arylsalkyl-carboxamide compositions and methods
GB0425661D0 (en) 2004-11-23 2004-12-22 Givaudan Sa Organic compounds
EP1814975A1 (de) 2004-11-29 2007-08-08 Givaudan SA Substratpflegeprodukt
DE602006017038D1 (de) 2005-03-01 2010-11-04 Givaudan Sa Menthancarbonsäureamidderivate mit kühlenden eigenschaften
GB0504194D0 (en) 2005-03-02 2005-04-06 Givaudan Sa Organic compounds
MX2007010576A (es) 2005-03-24 2007-10-04 Givaudan Sa Compuestos refrescantes.
CN101184470A (zh) 2005-05-27 2008-05-21 吉万奥丹股份有限公司 清凉化合物
US9452982B2 (en) 2005-08-15 2016-09-27 Givaudan, S.A. Pyridinyl cyclohexanecarboxamide cooling compounds
US8981180B2 (en) 2007-07-09 2015-03-17 Bayer Cropscience N.V. Brassica plant comprising mutant fatty acyl-ACP thioesterase alleles
US8377422B2 (en) 2007-12-07 2013-02-19 Givaudan S.A. Carboxamide derivatives having cooling properties

Also Published As

Publication number Publication date
EP1685093B1 (de) 2010-04-14
DE602004026619D1 (en) 2010-05-27
USRE44339E1 (en) 2013-07-02
BRPI0416770A (pt) 2007-02-27
EP1685093B3 (de) 2012-04-11
WO2005049553A1 (en) 2005-06-02
BRPI0416770B1 (pt) 2014-05-13
CN100582089C (zh) 2010-01-20
US7414152B2 (en) 2008-08-19
US20060276667A1 (en) 2006-12-07
PL1685093T6 (pl) 2012-10-31
JP2007511546A (ja) 2007-05-10
PL1685093T3 (pl) 2010-10-29
ES2342466T3 (es) 2010-07-07
JP4786544B2 (ja) 2011-10-05
CN1878746A (zh) 2006-12-13
EP1685093A1 (de) 2006-08-02
ES2342466T7 (es) 2012-11-19

Similar Documents

Publication Publication Date Title
ATE464283T1 (de) N-substituierte p-menthancarbonsäureamide
ES2543607T3 (es) Ciertas amidas sustituidas, método de obtención, y método de su uso
ATE302549T1 (de) N-phenyl-4-(4-pyridyl)-2-pyrimidinamine-derivat
MXPA05010652A (es) Pirazoles sustituidos.
TW200635509A (en) 5-Alkoxyalkyl-6-alkyl-7-aminoazolopyrimidines, process for their preparation, their use for controlling harmful fungi, and compositions comprising them
EA200601620A1 (ru) 5,6-диалкил-7-аминотриазолопиримидины, способ их получения и их применение для борьбы с патогенными растениями, а также содержащие их средства
DK1265606T3 (da) Celleadhæsionsinhibitorer
WO2007120379A3 (en) Sulfonanilide analogs as selective aromatase modulators
DE602004015331D1 (de) Verfahren für fluorcytidinderivate
TW200616954A (en) N-(1h-indolyl)-1h-indole-2-carboxamide derivatives, their preparation and their application in therapeutics
WO2003022797A1 (en) Carba-sugar amine derivatives and treatments for disorder of glycolipid metabolism containing the same as the active ingredient
ATE287403T1 (de) 6-phenylbenzonaphthyidine
MXPA05010650A (es) Pirazoles sustituidos.
WO2003024913A1 (en) SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-κB INHIBITING ACTIVITY
MY159418A (en) New derivatives of flavones, their preparation process, their use as medicaments, pharmaceutical compositions and new use
ZA200900555B (en) Cyclic amine compound
ATE366727T1 (de) Diaryl-1,2,4-triazolderivate als hochselektive cyclooxygenase-2-inhibitoren
UA99113C2 (ru) Жидкая пестицидная композиция, содержащая n-фенилсемикарбазоновые пестицидные соединения
PL1644340T3 (pl) N-[({4-podstawione związki piperazyn-1-ylo}sulfonylometylo)alkilo]-n-hydroksyformamidowe jako inhibitory metaloproteinazy
TW200612944A (en) 4-(2,4-dichloro-5-methoxyphenyl)amino-6-methoxy-7-{[5-(substituted-amino)methyl]-3-furyl}-3-quinolinecarbonitriles as kinase inhibitors
ATE367377T1 (de) Bis(5-aryl-2-pyridyl)derivate
ATE290783T1 (de) Fungizidzusammensetzung auf halogensulfonbasis für verpackungen
TH92804A (de)
AR038895A1 (es) Un procedimiento para la produccion de derivados amida tipo ramoplanina
DE502004005303D1 (de) Fungizide mischungen auf der basis von oximetherderivaten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties