ATE540667T1 - Verbindungen mit kühlender wirkung - Google Patents
Verbindungen mit kühlender wirkungInfo
- Publication number
- ATE540667T1 ATE540667T1 AT08757259T AT08757259T ATE540667T1 AT E540667 T1 ATE540667 T1 AT E540667T1 AT 08757259 T AT08757259 T AT 08757259T AT 08757259 T AT08757259 T AT 08757259T AT E540667 T1 ATE540667 T1 AT E540667T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- cooling effect
- bornyl
- group
- moieties
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000001816 cooling Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical group C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 abstract 1
- -1 2-methylbornyl Chemical group 0.000 abstract 1
- 230000035597 cooling sensation Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
- C07C69/38—Malonic acid esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
- C07C69/40—Succinic acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
- A61K2800/244—Endothermic; Cooling; Cooling sensation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93438207P | 2007-06-13 | 2007-06-13 | |
| PCT/CH2008/000266 WO2008151460A2 (en) | 2007-06-13 | 2008-06-11 | Cooling compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE540667T1 true ATE540667T1 (de) | 2012-01-15 |
Family
ID=40130233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08757259T ATE540667T1 (de) | 2007-06-13 | 2008-06-11 | Verbindungen mit kühlender wirkung |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US7959958B2 (de) |
| EP (1) | EP2167024B1 (de) |
| AT (1) | ATE540667T1 (de) |
| WO (1) | WO2008151460A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101583287A (zh) * | 2006-12-20 | 2009-11-18 | 奇华顿荷兰服务有限责任公司 | N-取代-对薄荷烷-3-甲酰胺及其用途 |
| US7935848B2 (en) * | 2007-05-23 | 2011-05-03 | Givaudan S.A. | Butone derivatives useful as cooling agents |
| WO2009076792A1 (en) * | 2007-12-19 | 2009-06-25 | Givaudan Sa | Cooling compounds |
| EP2250154A1 (de) * | 2008-01-17 | 2010-11-17 | Givaudan SA | Benzimidazolderivate und ihre verwendung als kühlmittel |
| US10392371B2 (en) | 2015-10-01 | 2019-08-27 | Senomyx, Inc. | Compounds useful as modulators of TRPM8 |
| EP3509642A1 (de) | 2016-09-12 | 2019-07-17 | ST IP Holding AG | Formulierungen von 4-methyl-5-(pyrazin-2-yl)-3h-1,2-dithiol-3-thion sowie verfahren zur herstellung und verwendung davon |
| CA3036630A1 (en) | 2016-09-12 | 2018-03-15 | St Ip Holding Ag | Formulations of 4-methyl-5-(pyrazin-2-yl)-3h-1,2-dithiole-3-thione, taste-modified formulations, and methods of making and using same |
| US20200188289A1 (en) | 2017-05-15 | 2020-06-18 | Firmenich Sa | Compositions comprising essential oils |
| BR112020003233B1 (pt) | 2017-12-20 | 2023-11-07 | Firmenich S.A. | Composições para cuidado oral |
| EP3806661B1 (de) | 2018-08-10 | 2025-07-02 | Firmenich Incorporated | Verwendung von t2r54 antagonisten |
| KR102695013B1 (ko) | 2019-04-24 | 2024-08-13 | 삼성전자주식회사 | 펠리클 조립체의 제조 방법 및 포토마스크 조립체의 제조 방법 |
| US11135220B1 (en) | 2020-04-08 | 2021-10-05 | St Ip Holding Ag | Methods of treating viral infections with formulated compositions comprising 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione |
| JP2022040048A (ja) * | 2020-08-28 | 2022-03-10 | 三栄源エフ・エフ・アイ株式会社 | 冷涼感増強剤 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3516943A (en) | 1966-12-06 | 1970-06-23 | Ncr Co | Replacement of capsule contents by diffusion |
| GB1351761A (en) | 1971-02-04 | 1974-05-01 | Wilkinson Sword Ltd | Substituted p-menthane carboxamides and compositions containing them |
| US4150052A (en) | 1971-02-04 | 1979-04-17 | Wilkinson Sword Limited | N-substituted paramenthane carboxamides |
| GB1351762A (en) | 1971-02-14 | 1974-05-01 | Wilkinson Sword Ltd | Tobacco and tobacco-containing manufactures |
| GB1502680A (en) * | 1975-06-03 | 1978-03-01 | Wilkinson Sword Ltd | Compositions for application to or consumption by the human body and containing compounds having a physiological cooling effect |
| US4285984A (en) | 1976-08-09 | 1981-08-25 | Givaudan Corporation | Flavoring with dialkylamino-alkylene mercaptans and sulfides |
| US4351347A (en) * | 1981-03-25 | 1982-09-28 | International Flavors & Fragrances Inc. | Organoleptic uses of norbornyl ethers and esters |
| EP0199257A3 (de) * | 1985-04-15 | 1988-08-10 | General Foods Corporation | Ester von L-Aminodicarboxylsäure und eine geniessbare, sie als Süssstoff enthaltende Zusammensetzung |
| US5759599A (en) | 1992-03-30 | 1998-06-02 | Givaudan Roure Flavors Corporation | Method of flavoring and mechanically processing foods with polymer encapsulated flavor oils |
| JP3001332B2 (ja) * | 1992-05-11 | 2000-01-24 | 日本化薬株式会社 | 光学活性体（−）−（１ｓ，２ｓ，４ｒ）−エキソー２−ノルボルナノールの製造方法 |
| WO1997016078A1 (de) | 1995-10-27 | 1997-05-09 | Givaudan-Roure (International) S.A. | Aromengranulat |
| US6306818B1 (en) | 1996-06-24 | 2001-10-23 | Givaudan Roure (International) Sa | Fragrance precursors |
| AU733927B2 (en) | 1996-10-09 | 2001-05-31 | Givaudan-Roure (International) Sa | Process for preparing beads as food additive |
| BR9711875A (pt) | 1996-10-09 | 1999-08-24 | Givaudan Roure Int | Processo para a prepara-Æo de contas como aditivo alimenticio ou de tabaco |
| US6039901A (en) | 1997-01-31 | 2000-03-21 | Givaudan Roure Flavors Corporation | Enzymatically protein encapsulating oil particles by complex coacervation |
| US6045835A (en) | 1997-10-08 | 2000-04-04 | Givaudan Roure (International) Sa | Method of encapsulating flavors and fragrances by controlled water transport into microcapsules |
| US6106875A (en) | 1997-10-08 | 2000-08-22 | Givaudan Roure (International) Sa | Method of encapsulating flavors and fragrances by controlled water transport into microcapsules |
| SG74666A1 (en) | 1997-10-21 | 2000-08-22 | Givaudan Roure Int | Beta-ketoester |
| SG71201A1 (en) | 1998-04-20 | 2000-03-21 | Givaudan Roure Int | Hydroxa-methyl-hexanones |
| ATE367845T1 (de) | 1998-06-15 | 2007-08-15 | Procter & Gamble | Riechstoffzusammensetzungen |
| WO2000004009A1 (de) | 1998-07-17 | 2000-01-27 | Givaudan Roure (International) Sa | Dicarboalkoxy dioxolanes |
| EP0987018A3 (de) | 1998-08-27 | 2000-04-26 | Givaudan Roure (International) S.A. | Nachschäumendes Douche-Gel |
| US6805893B2 (en) | 1999-05-28 | 2004-10-19 | Givaudan Sa | Mercapto-alkanol flavor compounds |
| DE60006448T2 (de) | 1999-05-28 | 2004-08-26 | Givaudan S.A. | Mercaptoalkohol-Verbindungen als als Geschmackstoffe |
| US6689740B1 (en) | 1999-06-15 | 2004-02-10 | Givaudan Sa | Method for preparing fragrance products |
| ZA200003120B (en) | 1999-06-30 | 2001-01-02 | Givaudan Roure Int | Encapsulation of active ingredients. |
| AU7247000A (en) | 2000-01-11 | 2001-07-19 | Givaudan Sa | Composite materials |
| US6335047B1 (en) | 2000-11-06 | 2002-01-01 | Givaudan Sa | Epoxydecenal isomers |
| US6451366B1 (en) | 2000-11-06 | 2002-09-17 | Givaudan Sa | Epoxydecenal isomers |
| US20030165587A1 (en) | 2002-02-28 | 2003-09-04 | Givaudan Sa | Production of 2-furfurylthiol in brassica seed and use of same |
| EP1348423A1 (de) | 2002-03-27 | 2003-10-01 | Givaudan SA | Duftstoffzusammensetzungen |
| CN1291971C (zh) | 2002-07-25 | 2006-12-27 | 吉万奥丹股份有限公司 | 食用香料化合物 |
| MXPA05004251A (es) | 2002-10-21 | 2005-07-05 | Givaudan Sa | Composiciones pesticidas. |
| WO2004043165A1 (en) | 2002-11-14 | 2004-05-27 | Givaudan Sa | Edible film containing food acid |
| GB0301662D0 (en) | 2003-01-24 | 2003-02-26 | Givaudan Sa | Improvements in or relating to organic compounds |
| GB0306152D0 (en) | 2003-03-19 | 2003-04-23 | Givaudan Sa | Method |
| WO2005048965A2 (en) * | 2003-11-13 | 2005-06-02 | Wm. Wrigley Jr. Company | Method and composition for breath freshening |
| DE602004026619D1 (en) | 2003-11-21 | 2010-05-27 | Givaudan Sa | N-substituierte p-menthancarbonsäureamide |
| EP1814975A1 (de) | 2004-11-29 | 2007-08-08 | Givaudan SA | Substratpflegeprodukt |
| MX2007010576A (es) | 2005-03-24 | 2007-10-04 | Givaudan Sa | Compuestos refrescantes. |
| US9452982B2 (en) | 2005-08-15 | 2016-09-27 | Givaudan, S.A. | Pyridinyl cyclohexanecarboxamide cooling compounds |
-
2008
- 2008-06-11 EP EP08757259A patent/EP2167024B1/de not_active Not-in-force
- 2008-06-11 AT AT08757259T patent/ATE540667T1/de active
- 2008-06-11 WO PCT/CH2008/000266 patent/WO2008151460A2/en not_active Ceased
- 2008-06-12 US US12/137,928 patent/US7959958B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008151460A3 (en) | 2010-04-01 |
| US7959958B2 (en) | 2011-06-14 |
| EP2167024A2 (de) | 2010-03-31 |
| EP2167024B1 (de) | 2012-01-11 |
| WO2008151460A2 (en) | 2008-12-18 |
| US20080311232A1 (en) | 2008-12-18 |
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