ATE540667T1 - Verbindungen mit kühlender wirkung - Google Patents

Verbindungen mit kühlender wirkung

Info

Publication number
ATE540667T1
ATE540667T1 AT08757259T AT08757259T ATE540667T1 AT E540667 T1 ATE540667 T1 AT E540667T1 AT 08757259 T AT08757259 T AT 08757259T AT 08757259 T AT08757259 T AT 08757259T AT E540667 T1 ATE540667 T1 AT E540667T1
Authority
AT
Austria
Prior art keywords
compounds
cooling effect
bornyl
group
moieties
Prior art date
Application number
AT08757259T
Other languages
English (en)
Inventor
Stefan Furrer
Gregory Yep
Eric Flamme
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Sa filed Critical Givaudan Sa
Application granted granted Critical
Publication of ATE540667T1 publication Critical patent/ATE540667T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/38—Malonic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/40—Succinic acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24—Thermal properties
    • A61K2800/244—Endothermic; Cooling; Cooling sensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
AT08757259T 2007-06-13 2008-06-11 Verbindungen mit kühlender wirkung ATE540667T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93438207P 2007-06-13 2007-06-13
PCT/CH2008/000266 WO2008151460A2 (en) 2007-06-13 2008-06-11 Cooling compounds

Publications (1)

Publication Number Publication Date
ATE540667T1 true ATE540667T1 (de) 2012-01-15

Family

ID=40130233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08757259T ATE540667T1 (de) 2007-06-13 2008-06-11 Verbindungen mit kühlender wirkung

Country Status (4)

Country Link
US (1) US7959958B2 (de)
EP (1) EP2167024B1 (de)
AT (1) ATE540667T1 (de)
WO (1) WO2008151460A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101583287A (zh) * 2006-12-20 2009-11-18 奇华顿荷兰服务有限责任公司 N-取代-对薄荷烷-3-甲酰胺及其用途
CN101677930A (zh) * 2007-05-23 2010-03-24 吉万奥丹股份有限公司 用作清凉剂的丁酮衍生物
WO2009076792A1 (en) * 2007-12-19 2009-06-25 Givaudan Sa Cooling compounds
US20100297038A1 (en) * 2008-01-17 2010-11-25 Givaudan S.A. Benzimidazole Derivatives And Their Use As Cooling Agents
BR112018006471B1 (pt) 2015-10-01 2024-02-27 Senomyx, Inc Composto, composição, método de modular o membro de melastina do canal potencial do receptor transitório 8 (trpm8), método de modular a sensação de resfrescância de uma composição e método de induzir uma sensação de refrescância em um ser humano ou animal
EP3509642A1 (de) 2016-09-12 2019-07-17 ST IP Holding AG Formulierungen von 4-methyl-5-(pyrazin-2-yl)-3h-1,2-dithiol-3-thion sowie verfahren zur herstellung und verwendung davon
AU2017322544B2 (en) 2016-09-12 2022-06-02 St Ip Holding Ag Formulations of 4-methyl-5-(pyrazin-2-yl)-3H-1.2-dithiole-3-thione, taste-modified formulations, and methods of making and using same
BR112019023827A2 (pt) 2017-05-15 2020-06-09 Firmenich & Cie composições que compreendem óleos essenciais
BR112020003233B1 (pt) 2017-12-20 2023-11-07 Firmenich S.A. Composições para cuidado oral
WO2020033669A1 (en) 2018-08-10 2020-02-13 Firmenich Incorporated Antagonists of t2r54 and compositions and uses thereof
KR102695013B1 (ko) 2019-04-24 2024-08-13 삼성전자주식회사 펠리클 조립체의 제조 방법 및 포토마스크 조립체의 제조 방법
US11135220B1 (en) 2020-04-08 2021-10-05 St Ip Holding Ag Methods of treating viral infections with formulated compositions comprising 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione
JP7857740B2 (ja) * 2020-08-28 2026-05-13 三栄源エフ・エフ・アイ株式会社 冷涼感増強剤

Family Cites Families (41)

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Publication number Priority date Publication date Assignee Title
US3516943A (en) 1966-12-06 1970-06-23 Ncr Co Replacement of capsule contents by diffusion
US4150052A (en) 1971-02-04 1979-04-17 Wilkinson Sword Limited N-substituted paramenthane carboxamides
GB1351761A (en) 1971-02-04 1974-05-01 Wilkinson Sword Ltd Substituted p-menthane carboxamides and compositions containing them
GB1351762A (en) 1971-02-14 1974-05-01 Wilkinson Sword Ltd Tobacco and tobacco-containing manufactures
GB1502680A (en) * 1975-06-03 1978-03-01 Wilkinson Sword Ltd Compositions for application to or consumption by the human body and containing compounds having a physiological cooling effect
US4285984A (en) 1976-08-09 1981-08-25 Givaudan Corporation Flavoring with dialkylamino-alkylene mercaptans and sulfides
US4351347A (en) * 1981-03-25 1982-09-28 International Flavors & Fragrances Inc. Organoleptic uses of norbornyl ethers and esters
EP0199257A3 (de) * 1985-04-15 1988-08-10 General Foods Corporation Ester von L-Aminodicarboxylsäure und eine geniessbare, sie als Süssstoff enthaltende Zusammensetzung
US5759599A (en) 1992-03-30 1998-06-02 Givaudan Roure Flavors Corporation Method of flavoring and mechanically processing foods with polymer encapsulated flavor oils
JP3001332B2 (ja) * 1992-05-11 2000-01-24 日本化薬株式会社 光学活性体（−）−（１ｓ，２ｓ，４ｒ）−エキソー２−ノルボルナノールの製造方法
ES2175130T3 (es) 1995-10-27 2002-11-16 Givaudan Sa Granulado de aromas.
US6306818B1 (en) 1996-06-24 2001-10-23 Givaudan Roure (International) Sa Fragrance precursors
HUP9904490A3 (en) 1996-10-09 2000-06-28 Givaudan Roure Int Process for preparing beads as food or tobacco additive
ES2212085T3 (es) 1996-10-09 2004-07-16 Givaudan Sa Procedimiento para la preparacion de granulos como aditivo para alimentos.
US6039901A (en) 1997-01-31 2000-03-21 Givaudan Roure Flavors Corporation Enzymatically protein encapsulating oil particles by complex coacervation
US6106875A (en) 1997-10-08 2000-08-22 Givaudan Roure (International) Sa Method of encapsulating flavors and fragrances by controlled water transport into microcapsules
US6045835A (en) 1997-10-08 2000-04-04 Givaudan Roure (International) Sa Method of encapsulating flavors and fragrances by controlled water transport into microcapsules
SG74666A1 (en) 1997-10-21 2000-08-22 Givaudan Roure Int Beta-ketoester
SG71201A1 (en) 1998-04-20 2000-03-21 Givaudan Roure Int Hydroxa-methyl-hexanones
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AU7247000A (en) 2000-01-11 2001-07-19 Givaudan Sa Composite materials
US6335047B1 (en) 2000-11-06 2002-01-01 Givaudan Sa Epoxydecenal isomers
US6451366B1 (en) 2000-11-06 2002-09-17 Givaudan Sa Epoxydecenal isomers
US20030165587A1 (en) 2002-02-28 2003-09-04 Givaudan Sa Production of 2-furfurylthiol in brassica seed and use of same
EP1348423A1 (de) 2002-03-27 2003-10-01 Givaudan SA Duftstoffzusammensetzungen
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AU2003277788A1 (en) 2002-11-14 2004-06-03 Givaudan Sa Edible film containing food acid
GB0301662D0 (en) 2003-01-24 2003-02-26 Givaudan Sa Improvements in or relating to organic compounds
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CN100582089C (zh) 2003-11-21 2010-01-20 吉万奥丹股份有限公司 N-取代的对-薄荷烷甲酰胺
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JP2008535806A (ja) * 2005-03-24 2008-09-04 ジボダン エス エー 清涼化合物
CN101257949B (zh) 2005-08-15 2011-01-19 奇华顿股份有限公司 清凉化合物

Also Published As

Publication number Publication date
EP2167024B1 (de) 2012-01-11
WO2008151460A3 (en) 2010-04-01
EP2167024A2 (de) 2010-03-31
US20080311232A1 (en) 2008-12-18
US7959958B2 (en) 2011-06-14
WO2008151460A2 (en) 2008-12-18

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