ATE366727T1 - Diaryl-1,2,4-triazolderivate als hochselektive cyclooxygenase-2-inhibitoren - Google Patents
Diaryl-1,2,4-triazolderivate als hochselektive cyclooxygenase-2-inhibitorenInfo
- Publication number
- ATE366727T1 ATE366727T1 AT02793527T AT02793527T ATE366727T1 AT E366727 T1 ATE366727 T1 AT E366727T1 AT 02793527 T AT02793527 T AT 02793527T AT 02793527 T AT02793527 T AT 02793527T AT E366727 T1 ATE366727 T1 AT E366727T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- diaryl
- highly selective
- inhibitors
- selective cyclooxygenase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020010086698A KR100686537B1 (ko) | 2001-12-28 | 2001-12-28 | 사이클로옥시게나제-2 의 저해제로서 선택성이 뛰어난디아릴 1,2,4-트리아졸 유도체 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE366727T1 true ATE366727T1 (de) | 2007-08-15 |
Family
ID=19717755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02793527T ATE366727T1 (de) | 2001-12-28 | 2002-12-27 | Diaryl-1,2,4-triazolderivate als hochselektive cyclooxygenase-2-inhibitoren |
Country Status (10)
Country | Link |
---|---|
US (2) | US7169929B2 (de) |
EP (1) | EP1458706B1 (de) |
JP (1) | JP4242286B2 (de) |
KR (1) | KR100686537B1 (de) |
CN (1) | CN1290842C (de) |
AT (1) | ATE366727T1 (de) |
AU (1) | AU2002359985A1 (de) |
DE (1) | DE60221152T2 (de) |
ES (1) | ES2286321T3 (de) |
WO (1) | WO2003055875A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100491317B1 (ko) * | 2002-11-26 | 2005-05-24 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
KR100470076B1 (ko) * | 2002-11-27 | 2005-02-05 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
KR100576343B1 (ko) * | 2004-07-22 | 2006-05-03 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
US8188128B2 (en) * | 2005-05-12 | 2012-05-29 | The University Of Medicine And Dentistry Of New Jersey | Opioid receptor subtype-selective agents |
CN102464652B (zh) | 2010-11-02 | 2013-08-28 | 北京欧博方医药科技有限公司 | 咪唑衍生物、制备方法及用途 |
WO2012070596A1 (en) * | 2010-11-26 | 2012-05-31 | Semiconductor Energy Laboratory Co., Ltd. | Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US125368A (en) * | 1872-04-02 | Improvement in railway rails | ||
US75507A (en) * | 1868-03-17 | ingk adams | ||
EP0840608B1 (de) * | 1995-07-21 | 2004-10-06 | Savvipharm Inc. | Orotatsalze von 5-amino- oder substituierten amino-1,2,3-triazolen zur behandlung von neoplasmen |
RO118566B1 (ro) * | 1996-11-19 | 2003-07-30 | Searle & Co | Metoda pentru prevenirea si tratamentul unei boli asociata cu angiogeneza |
NZ500141A (en) * | 1997-04-18 | 2002-05-31 | G | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders |
TW438784B (en) * | 1997-08-29 | 2001-06-07 | Ssp Co Ltd | Triazole derivative or salt thereof and pharmaceutical composition for treating mycosis containing the same |
EP1510519B1 (de) * | 1997-09-05 | 2006-02-15 | Glaxo Group Limited | Pharmazeutische Zusammensetzung, enthaltend 2,3-Diaryl-Pyrazolo[1,5-b]Pyridazin Derivate |
EP1099695A1 (de) * | 1999-11-09 | 2001-05-16 | Laboratoire Theramex S.A. | 5-Aryl-1H-1,2,4-triazolverbindungen als Cyclooxygenase-2 Inhibitoren und diese enthaltende pharmazeutische Zusammensetzungen |
ATE291019T1 (de) * | 1999-12-03 | 2005-04-15 | Pfizer Prod Inc | Heterocyclo-alkylsulfonylpyrazolderivate zur verwendung als anti-imflammatorische oder analgetische verbindungen |
EP1142889A1 (de) * | 2000-04-03 | 2001-10-10 | Pfizer Products Inc. | Pyrazolderivate als entzündungs-/schmerzhemmende Mittel |
CA2390181A1 (en) * | 2001-07-05 | 2003-01-05 | Andrei Shavnya | Sulfonyl aryl triazoles as anti-inflammatory/analgesic agents |
DE60204633T2 (de) * | 2001-07-05 | 2006-06-14 | Pfizer Prod Inc | Sulfonyl-Heteroaryl-Triazole als entzündungshemmende und analgetische Mittel |
KR100467668B1 (ko) * | 2002-08-07 | 2005-01-24 | 씨제이 주식회사 | 1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물 |
-
2001
- 2001-12-28 KR KR1020010086698A patent/KR100686537B1/ko not_active IP Right Cessation
-
2002
- 2002-12-27 ES ES02793527T patent/ES2286321T3/es not_active Expired - Lifetime
- 2002-12-27 WO PCT/KR2002/002447 patent/WO2003055875A1/en active IP Right Grant
- 2002-12-27 CN CNB028262638A patent/CN1290842C/zh not_active Expired - Fee Related
- 2002-12-27 JP JP2003556405A patent/JP4242286B2/ja not_active Expired - Fee Related
- 2002-12-27 US US10/498,157 patent/US7169929B2/en not_active Expired - Lifetime
- 2002-12-27 AU AU2002359985A patent/AU2002359985A1/en not_active Abandoned
- 2002-12-27 EP EP02793527A patent/EP1458706B1/de not_active Expired - Lifetime
- 2002-12-27 DE DE60221152T patent/DE60221152T2/de not_active Expired - Lifetime
- 2002-12-27 AT AT02793527T patent/ATE366727T1/de not_active IP Right Cessation
-
2005
- 2005-09-12 US US11/224,787 patent/US7135572B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1458706B1 (de) | 2007-07-11 |
KR20030056481A (ko) | 2003-07-04 |
US20060009495A1 (en) | 2006-01-12 |
AU2002359985A1 (en) | 2003-07-15 |
JP4242286B2 (ja) | 2009-03-25 |
CN1290842C (zh) | 2006-12-20 |
US7169929B2 (en) | 2007-01-30 |
DE60221152T2 (de) | 2008-03-20 |
EP1458706A4 (de) | 2005-06-08 |
DE60221152D1 (en) | 2007-08-23 |
US7135572B2 (en) | 2006-11-14 |
JP2005518396A (ja) | 2005-06-23 |
EP1458706A1 (de) | 2004-09-22 |
KR100686537B1 (ko) | 2007-02-27 |
ES2286321T3 (es) | 2007-12-01 |
WO2003055875A1 (en) | 2003-07-10 |
US20050075373A1 (en) | 2005-04-07 |
CN1608060A (zh) | 2005-04-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |