ATE458042T1 - Verfahren zur herstellung von scyllo-inositol - Google Patents

Verfahren zur herstellung von scyllo-inositol

Info

Publication number
ATE458042T1
ATE458042T1 AT04817164T AT04817164T ATE458042T1 AT E458042 T1 ATE458042 T1 AT E458042T1 AT 04817164 T AT04817164 T AT 04817164T AT 04817164 T AT04817164 T AT 04817164T AT E458042 T1 ATE458042 T1 AT E458042T1
Authority
AT
Austria
Prior art keywords
inositol
scyllo
myo
complex
novel
Prior art date
Application number
AT04817164T
Other languages
English (en)
Inventor
Masanori Yamaguchi
Yuichi Kita
Tetsuya Mori
Kenji Kanbe
Akihiro Tomoda
Atsushi Takahashi
Wakako Ichikawa
Original Assignee
Hokko Chem Ind Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokko Chem Ind Co filed Critical Hokko Chem Ind Co
Application granted granted Critical
Publication of ATE458042T1 publication Critical patent/ATE458042T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26Ketones
AT04817164T 2003-10-14 2004-10-14 Verfahren zur herstellung von scyllo-inositol ATE458042T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2003353491 2003-10-14
JP2003353490 2003-10-14
JP2004018128 2004-01-27
JP2004194088 2004-06-30
PCT/JP2004/015174 WO2005035774A1 (ja) 2003-10-14 2004-10-14 シロ−イノシトールの製造方法

Publications (1)

Publication Number Publication Date
ATE458042T1 true ATE458042T1 (de) 2010-03-15

Family

ID=34437726

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04817164T ATE458042T1 (de) 2003-10-14 2004-10-14 Verfahren zur herstellung von scyllo-inositol

Country Status (11)

Country Link
US (4) US7745671B2 (de)
EP (3) EP1674578B1 (de)
JP (3) JP4526485B2 (de)
KR (3) KR101314079B1 (de)
AT (1) ATE458042T1 (de)
CA (3) CA2542560C (de)
DE (1) DE602004025596D1 (de)
DK (2) DK1674578T3 (de)
ES (2) ES2341964T3 (de)
PT (2) PT2058390E (de)
WO (1) WO2005035774A1 (de)

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* Cited by examiner, † Cited by third party
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US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
ZA200704872B (en) * 2004-11-17 2008-12-31 Mclaurin Joanne Compositions comprising scyllo-inositol derivatives and methods to treat disorders of protein aggregation
JP4761763B2 (ja) * 2004-12-16 2011-08-31 北興化学工業株式会社 ホウ酸選択的結合物質およびホウ酸の除去又は回収方法
JP4659545B2 (ja) * 2005-07-20 2011-03-30 北興化学工業株式会社 シロ−イノソースの製造方法
WO2007119108A2 (en) * 2005-10-13 2007-10-25 Waratah Pharmaceuticals Inc. Inositol derivatives and their uses in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence
US20070197452A1 (en) * 2006-02-17 2007-08-23 Mclaurin Joanne Treatment of amyloid-related diseases
CA2642647A1 (en) * 2006-02-17 2007-11-15 Joanne Mclaurin Compositions and methods for treatment of disorders of protein aggregation
WO2007101353A1 (en) * 2006-03-09 2007-09-13 Waratah Pharmaceuticals Inc. A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation
US20110028719A1 (en) * 2006-05-19 2011-02-03 Jacek Slon-Usakiewicz Screening methods for amyloid beta modulators
JP5101841B2 (ja) * 2006-06-15 2012-12-19 オルガノ株式会社 高分子多孔質体の製造方法
US20100173960A1 (en) * 2006-09-21 2010-07-08 Antonio Cruz The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases
JP2010510254A (ja) * 2006-11-24 2010-04-02 ワラタ ファーマシューティカルズ, インコーポレイテッド アルツハイマー病および関連の神経変性疾患のための併用処置
EP2114151A4 (de) * 2007-03-01 2010-03-17 Concourse Health Sciences Llc Isomere von inositol-niacinat und anwendungen davon
US20110105626A1 (en) * 2007-04-12 2011-05-05 Mclaurin Joanne Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases
US20100331267A1 (en) * 2007-04-12 2010-12-30 Mclaurin Joanne Use of cyclohexanehexol derivatives in the treatment of alpha-synucleinopathies
ES2425264T3 (es) * 2007-04-12 2013-10-14 Waratah Pharmaceuticals, Inc. Uso de derivados de ciclohexanohexol en el tratamiento de enfermedades oculares
US20100144891A1 (en) * 2007-04-12 2010-06-10 Mclaurin Joanne Use of cyclohexanehexol derivatives in the treatment of amyotrophic lateral sclerosis
WO2010040232A1 (en) * 2008-10-09 2010-04-15 Waratah Pharmaceuticals Inc. Use of scyllo-inositols for the treatment of macular degeneration-related disorders
US8962287B2 (en) * 2008-10-31 2015-02-24 National University Corporation Kobe University Scyllo-inositol-producing cell and scyllo-inositol production method using said cells
US8372367B2 (en) * 2009-10-26 2013-02-12 Emc Metals Corporation System and method for recovering boron values from plant tailings
AU2011215616A1 (en) * 2010-02-15 2012-09-06 Transition Therapeutics Ireland Limited Process for the preparation of scyllo-Inositol
WO2012051395A1 (en) 2010-10-13 2012-04-19 Elan Pharmaceuticals, Inc. Methods of synthesis of scyllitol and related compounds
JP2014515408A (ja) 2011-06-03 2014-06-30 エラン ファーマシューティカルズ,リミティド ライアビリティー カンパニー 行動及び精神障害の治療のためのシロ−イノシトール
US9505795B2 (en) 2012-02-02 2016-11-29 Asahi Kasei Chemicals Corporation Method for producing scyllo-inositol
KR102017776B1 (ko) * 2012-12-17 2019-09-03 주식회사 디와이내츄럴 휴면 세포 전환법을 이용한 d-카이로 이노시톨의 생산 방법
US10017537B2 (en) * 2013-04-15 2018-07-10 Korea Institute Of Science And Technology Peptide selectively binding to graphitic materials and volatile organic compounds
EP3085782B1 (de) * 2013-12-16 2019-08-14 Asahi Kasei Kabushiki Kaisha 2-desoxyscylloinosose-reduktase
WO2017029353A1 (en) 2015-08-20 2017-02-23 Transition Therapeutics Ireland Limited Treatment of behaviors in dementia patients
CN114181045B (zh) * 2021-12-02 2024-04-26 吉林海资生物工程技术有限公司 一种球形无水肌醇的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3405663A1 (de) 1984-02-17 1985-08-22 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur herstellung von scyllo-inosit
DE3642999A1 (de) 1986-12-17 1988-06-30 Merck Patent Gmbh Scyllo-inositverbindungen
JP2984043B2 (ja) 1990-09-18 1999-11-29 旭化成工業株式会社 ミオ・イノシトールデヒドロゲナーゼおよびその製造法
JPH05192163A (ja) 1991-09-30 1993-08-03 Suntory Ltd イノシトールデヒドロゲナーゼ遺伝子
JP3251976B2 (ja) 1992-06-23 2002-01-28 旭化成株式会社 ミオ・イノシトールデヒドロゲナーゼを生産する実質上純粋な微生物
US5412080A (en) 1993-08-25 1995-05-02 President And Fellow Of Harvard College Enterobactin compounds
JP3630344B2 (ja) * 1995-11-17 2005-03-16 北興化学工業株式会社 イノシトール立体異性体の製造方法
JP3944333B2 (ja) * 1999-06-25 2007-07-11 北興化学工業株式会社 D−キロ−イノシトールの新規製造方法
JP3981597B2 (ja) * 2001-06-25 2007-09-26 北興化学工業株式会社 シロ−イノソースの製造法及びシロ−イノシトールの製造法

Also Published As

Publication number Publication date
US20060240534A1 (en) 2006-10-26
PT1674578E (pt) 2010-05-21
CA2542560A1 (en) 2005-04-21
EP2058390A1 (de) 2009-05-13
US8715974B2 (en) 2014-05-06
JP2012228264A (ja) 2012-11-22
ES2404554T3 (es) 2013-05-28
JP5674724B2 (ja) 2015-02-25
JP2010187688A (ja) 2010-09-02
JPWO2005035774A1 (ja) 2006-12-21
KR101191675B1 (ko) 2012-10-17
JP5122599B2 (ja) 2013-01-16
EP2058390B1 (de) 2013-01-23
US20130196417A1 (en) 2013-08-01
KR20060129187A (ko) 2006-12-15
DK2058390T3 (da) 2013-05-06
US20100261238A1 (en) 2010-10-14
CA2852842A1 (en) 2005-04-21
DK1674578T3 (da) 2010-06-07
DE602004025596D1 (de) 2010-04-01
KR101314079B1 (ko) 2013-10-04
KR101173148B1 (ko) 2012-08-16
ES2341964T3 (es) 2010-06-30
EP1674578B1 (de) 2010-02-17
JP4526485B2 (ja) 2010-08-18
PT2058390E (pt) 2013-04-24
EP1674578A1 (de) 2006-06-28
US20140322775A1 (en) 2014-10-30
CA2542560C (en) 2012-07-10
KR20100127887A (ko) 2010-12-06
KR20120103731A (ko) 2012-09-19
US7745671B2 (en) 2010-06-29
US8409833B2 (en) 2013-04-02
EP1674578A4 (de) 2007-03-14
CA2774930A1 (en) 2005-04-21
CA2774930C (en) 2014-08-05
EP2298870A1 (de) 2011-03-23
WO2005035774A1 (ja) 2005-04-21

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