ATE437225T1 - Verfahren zur polynukleotidsynthese - Google Patents

Verfahren zur polynukleotidsynthese

Info

Publication number
ATE437225T1
ATE437225T1 AT01967728T AT01967728T ATE437225T1 AT E437225 T1 ATE437225 T1 AT E437225T1 AT 01967728 T AT01967728 T AT 01967728T AT 01967728 T AT01967728 T AT 01967728T AT E437225 T1 ATE437225 T1 AT E437225T1
Authority
AT
Austria
Prior art keywords
polynucleotide synthesis
loops
polynucleotides
isothermal
synthesis
Prior art date
Application number
AT01967728T
Other languages
English (en)
Inventor
Kentaro Nagamine
Original Assignee
Eiken Chemical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18768163&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE437225(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eiken Chemical filed Critical Eiken Chemical
Application granted granted Critical
Publication of ATE437225T1 publication Critical patent/ATE437225T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT01967728T 2000-09-19 2001-09-19 Verfahren zur polynukleotidsynthese ATE437225T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000283862 2000-09-19
PCT/JP2001/008142 WO2002024902A1 (en) 2000-09-19 2001-09-19 Method of synthesizing polynucleotide

Publications (1)

Publication Number Publication Date
ATE437225T1 true ATE437225T1 (de) 2009-08-15

Family

ID=18768163

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01967728T ATE437225T1 (de) 2000-09-19 2001-09-19 Verfahren zur polynukleotidsynthese

Country Status (9)

Country Link
US (3) US7374913B2 (de)
EP (2) EP1327679B1 (de)
JP (2) JP4918210B2 (de)
CN (1) CN1222614C (de)
AT (1) ATE437225T1 (de)
AU (1) AU2001288065A1 (de)
DE (1) DE60139331D1 (de)
ES (2) ES2327712T3 (de)
WO (1) WO2002024902A1 (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8445664B2 (en) * 1998-06-24 2013-05-21 Enzo Diagnostics, Inc. Kits for amplifying and detecting nucleic acid sequences
ATE437225T1 (de) * 2000-09-19 2009-08-15 Eiken Chemical Verfahren zur polynukleotidsynthese
WO2003070935A1 (en) 2002-02-20 2003-08-28 Sysmex Corporation PRIMERS FOR NUCLEIC ACID AMPLIFICATION IN DETECTING HOUSEKEEPING GENE mRNA AND TEST METHOD USING THESE PRIMERS
AU2003234932A1 (en) 2002-05-21 2003-12-02 Sysmex Corporation Nucleic acid amplification primers for detecting cytokeratins and examination method with the use of the primers
TW200413527A (en) * 2002-10-29 2004-08-01 Riken Amplification of nucleic acid
CN1813064B (zh) * 2003-06-27 2011-11-02 荣研化学株式会社 检测sars冠状病毒的方法
JP2005110587A (ja) * 2003-10-08 2005-04-28 Sapporo Breweries Ltd アリサイクロバチラス属菌検出用プライマー
US8206902B2 (en) 2003-12-25 2012-06-26 Riken Method of amplifying nucleic acid and method of detecting mutated nucleic acid using the same
JP2008000002A (ja) * 2004-09-30 2008-01-10 Sysmex Corp リブロース２リン酸カルボキシラーゼスモールチェーン１Ａ（ＲＢＣＳ−１Ａ）遺伝子及び／又は該遺伝子のｍＲＮＡを検出するための核酸増幅用プライマ、及び内部標準として該遺伝子及び／又は該遺伝子のｍＲＮＡを用いた検査方法。
EP2388340B1 (de) 2004-11-01 2013-04-03 Eiken Kagaku Kabushiki Kaisha Verfahren zum Nachweisen von H7-Geflügelpestvirus
JP2006254784A (ja) * 2005-03-17 2006-09-28 Institute Of Physical & Chemical Research プライマーダイマーからの非特異的増幅を減少させる方法
FR2885140B1 (fr) 2005-04-29 2010-12-31 Millipore Corp Procede de detection et de caracterisation de microorgarnismes sur une membrane.
US8956850B2 (en) * 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
WO2007069331A1 (ja) * 2005-12-16 2007-06-21 Eiken Kagaku Kabushiki Kaisha ヒト免疫不全ウイルス１型の検出方法
JP4580875B2 (ja) * 2006-01-20 2010-11-17 株式会社東芝 核酸検出法のためのプライマーの設計方法
JP4881623B2 (ja) 2006-01-27 2012-02-22 シスメックス株式会社 Ｃｅａ核酸増幅用プライマー、プライマーセット、及びがんの診断支援方法
CN101605911A (zh) * 2007-01-17 2009-12-16 梅里第安生物科学公司 有效用于核酸的环-介导的等温扩增(lamp)的稳定试剂和试剂盒
CA2622649C (en) 2007-03-09 2018-04-24 Riken Nucleic acid amplification method using primer exhibiting exciton effect
JP4410269B2 (ja) 2007-03-28 2010-02-03 株式会社東芝 Ｎ−アセチルトランスフェラーゼ２（ｎａｔ２）の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法
JP4410268B2 (ja) 2007-03-28 2010-02-03 株式会社東芝 メチレンテトラヒドロ葉酸還元酵素（ｍｔｈｆｒ）の遺伝子型を検出するための核酸プライマーセット及び核酸プローブ
JP4490988B2 (ja) 2007-04-26 2010-06-30 株式会社東芝 血清アミロイドａ１（ｓａａ１）の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法
US20100221787A1 (en) 2007-10-25 2010-09-02 Riken Isothermal amplification method and dna polymerase used in the same
EP2284281A4 (de) * 2008-03-28 2011-08-10 Sysmex Corp Reagens mit primer zum nachweis von mrna für cytokeratin-7
EP2298884B1 (de) 2008-05-28 2014-06-18 Kao Corporation Verfahren zum nachweis eines thermotoleranten bakteriums
CN103451285B (zh) 2008-05-29 2015-05-06 花王株式会社 宛氏拟青霉的检测方法
JPWO2010061922A1 (ja) 2008-11-27 2012-04-26 独立行政法人理化学研究所 新規ＭｕｔＳタンパク質およびそれを用いた変異の判定方法
EP2784508B1 (de) 2008-12-25 2017-06-14 Universal Bio Research Co., Ltd. Système d'analyse automatisé d'acide nucléique
GB0910302D0 (en) * 2009-06-15 2009-07-29 Lumora Ltd Nucleic acid amplification
JP5299981B1 (ja) 2011-09-08 2013-09-25 独立行政法人理化学研究所 プライマーセット及びそれを用いた標的核酸配列の増幅方法並びに変異核酸の検出方法
CN103975061A (zh) 2011-10-31 2014-08-06 荣研化学株式会社 靶核酸的检测方法
WO2014085687A1 (en) 2012-11-28 2014-06-05 Abwiz Bio, Inc. Preparation of gene-specific templates for the use in single primer amplification
US9677981B2 (en) 2013-03-15 2017-06-13 3M Innovative Properties Company Sample concentrator and method of use
JP2016538882A (ja) 2013-10-30 2016-12-15 グリーン ライフ バイオテック，エルエルシー カンキツグリーニング病のための病因定量システム及び治療方法
EP3169793B1 (de) 2014-07-16 2022-07-06 Tangen Biosciences Inc. Isothermische verfahren zur amplifizierung von nukleinsäureproben
EP3215260B1 (de) 2014-11-03 2020-01-15 Tangen Biosciences Inc. Vorrichtung und verfahren für zellen-, sporen- oder viruserfassung und unterbrechung
WO2016098892A1 (ja) * 2014-12-19 2016-06-23 国立大学法人 長崎大学 ザイールエボラウイルス検出用プライマーセット、アッセイキットおよび増幅方法
JP6605238B2 (ja) * 2014-12-19 2019-11-13 国立大学法人 長崎大学 ザイールエボラウイルス検出用プライマーセット、アッセイキットおよび増幅方法
RU2017137788A (ru) 2015-03-30 2019-04-30 Гринлайт Байосайенсис, Инк. Бесклеточное получение рибонуклеиновой кислоты
JPWO2017212904A1 (ja) * 2016-06-06 2019-04-11 国立大学法人 宮崎大学 複数のプライマーセットを組み合わせたｌａｍｐ法を用いたアフリカ豚コレラウイルスの迅速検出法
US11299776B2 (en) * 2017-05-10 2022-04-12 Board Of Regents, The University Of Texas System Methods and devices related to amplifying nucleic acid at a variety of temperatures
JP7176682B2 (ja) 2018-02-22 2022-11-22 佐藤製薬株式会社 白癬菌の遺伝子をｌａｍｐ法により検出するためのプライマーセット及びそれを含むキット並びにそれらを用いて白癬菌を検出する方法
CN109658982B (zh) * 2018-12-25 2020-06-19 人和未来生物科技（长沙）有限公司 一种用于基因测序的引物设计方法及系统
TW202043484A (zh) * 2019-01-14 2020-12-01 英商卡美納生物科學公司 用於無模板幾何型酶催化性核酸合成之組成物和方法
CN113302314A (zh) 2019-01-15 2021-08-24 3M创新有限公司 用于产志贺毒素大肠杆菌(stec)检测的环介导的等温扩增引物
SG10201910254YA (en) 2019-11-04 2021-06-29 Denka Company Ltd Nucleic Acid Detection Method Using Lamp And Probe Detection
CN110878367A (zh) * 2019-12-05 2020-03-13 华南农业大学 一种可检测snp的新型cpa方法、引物组和试剂盒
CN115151656B (zh) 2020-02-27 2025-02-21 荣研化学株式会社 检测单链rna病毒的方法
EP4116438A4 (de) 2020-03-05 2024-04-03 Eiken Kagaku Kabushiki Kaisha Verfahren zur detektion von coronavirus (sars-cov-2)
MX2022011362A (es) 2020-03-13 2023-02-22 Uh Oh Labs Inc Cebador en bucle y metodo de bucle-de-bucle para detectar acido nucleico objetivo.
CA3177886A1 (en) 2020-05-05 2021-11-11 Miron TOKARSKI Diagnostic primers, kits and methods for viral detection
AU2021287968A1 (en) 2020-06-12 2023-02-09 Sherlock Biosciences, Inc. CRISPR-based SARS-CoV-2 detection
EP4193363A1 (de) 2020-08-07 2023-06-14 Oxford Nanopore Technologies plc Verfahren zur identifizierung von nukleinsäurebarcodes
CN112553300A (zh) * 2020-10-15 2021-03-26 德歌生物技术(山东)有限公司 引物设计方法、引物及等温扩增核酸片段的方法
EP3992300A1 (de) 2020-10-30 2022-05-04 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO Probenvorbehandlung zur isothermen amplifikation
EP4277998A4 (de) 2021-01-12 2025-01-01 Definitive Biotechnologies LLC Vorrichtung und verfahren zum nachweis von nukleinsäuren in biologischen proben
EP4291678A1 (de) 2021-02-09 2023-12-20 Sherlock Biosciences, Inc. Nukleinsäureamplifikation unter verwendung von promotorprimern
US11788129B2 (en) 2021-02-23 2023-10-17 Industrial Technology Research Institute Nucleic acid detection kit and nucleic acid detection method
PL437280A1 (pl) 2021-03-12 2022-09-19 Genomtec Spółka Akcyjna Zestaw starterów do powielania, sposób wykrywania infekcji bakteryjnej przenoszonej drogą płciową oraz zestaw do wykrywania infekcji
PL437660A1 (pl) 2021-04-22 2022-10-24 Genomtec Spółka Akcyjna Zestaw starterów, skład reagentów oraz metoda wykrywania bakterii Staphylococcus aureus opornej na metycylinę (MRSA)
WO2022226870A1 (zh) * 2021-04-29 2022-11-03 中国科学院大学宁波生命与健康产业研究院 恒温条件下合成核酸的方法及试剂盒和应用
CN113201583B (zh) * 2021-04-29 2022-02-08 国科宁波生命与健康产业研究院 恒温条件下合成核酸的方法及试剂盒和应用
JP2025500496A (ja) 2021-12-24 2025-01-09 エフ． ホフマン－ラ ロシュ アーゲー Ｌａｍｐ増幅産物の改良された検出
WO2025009968A1 (en) 2023-07-03 2025-01-09 Erasmus University Medical Center Rotterdam Methods for specific quantitation of the inducible hiv reservoir
EP4488391A1 (de) 2023-07-04 2025-01-08 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Verfahren und mittel zum nachweis von legionella

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743605B1 (en) 1998-06-24 2004-06-01 Enzo Life Sciences, Inc. Linear amplification of specific nucleic acid sequences
DE1020534T1 (de) * 1998-11-09 2001-03-01 Eiken Kagaku K.K., Tokio/Tokyo Verfahren zur synthetisieren von nukleinsäure
WO2001034790A1 (en) 1999-11-08 2001-05-17 Eiken Kagaku Kabushiki Kaisha Method for synthesizing nucleic acid
AU1057801A (en) 1999-11-08 2001-06-06 Eiken Kagaku Kabushiki Kaisha Method of detecting variation or polymorphism
CN100422323C (zh) * 2000-04-07 2008-10-01 荣研化学株式会社 使用双链核酸为模板扩增核酸的方法
ATE437225T1 (de) * 2000-09-19 2009-08-15 Eiken Chemical Verfahren zur polynukleotidsynthese

Also Published As

Publication number Publication date
US20040038253A1 (en) 2004-02-26
ES2390242T3 (es) 2012-11-07
EP2031058B1 (de) 2012-07-18
US7374913B2 (en) 2008-05-20
US20080213790A1 (en) 2008-09-04
DE60139331D1 (de) 2009-09-03
EP1327679B1 (de) 2009-07-22
US20080213842A1 (en) 2008-09-04
JP2012085652A (ja) 2012-05-10
JP4918210B2 (ja) 2012-04-18
CN1222614C (zh) 2005-10-12
US7846695B2 (en) 2010-12-07
EP1327679A1 (de) 2003-07-16
JPWO2002024902A1 (ja) 2004-01-29
HK1055445A1 (en) 2004-01-09
AU2001288065A1 (en) 2002-04-02
CN1474870A (zh) 2004-02-11
WO2002024902A1 (en) 2002-03-28
US7851186B2 (en) 2010-12-14
ES2327712T3 (es) 2009-11-03
EP1327679A4 (de) 2005-06-01
EP2031058A1 (de) 2009-03-04

Similar Documents

Publication Publication Date Title
ATE437225T1 (de) Verfahren zur polynukleotidsynthese
DK1828381T3 (da) Templatedirigeret split-and-mix-syntese af småmolekylebiblioteker
DE69940623D1 (de) Prozess zur Synthetisierung von Nukleinsäure
ATE429414T1 (de) Verfahren zur herstellung von organischen carbonaten
DK1608748T3 (da) Ligeringskodning af små molekyler
CY1109828T1 (el) Κατασκευασμενα προτυπα και η χρηση τους στην ενισχυση μοναδικου εκκινητη
ATE549381T1 (de) Verfahren zur herstellung von modifizierten pigmenten
UA83910C2 (ru) Способ получения 5-гидрокси-4-тиометилпиразольного соединения
ATE179411T1 (de) Verfahren zur herstellung von aromatischen carbamaten
ATE517857T1 (de) Herstellung von 4-phenylbutansäure
ATE323703T1 (de) Synthese von verbindungen die zur herstellung von ketorolac dienen
ATE318803T1 (de) Verfahren zur herstellung von laktonen
ATE179697T1 (de) Verfahren zur herstellung von aromatischen urethanen
DE602004012151D1 (de) Verfahren zur herstellung von chlorsulfonylisocyanat
ATE214046T1 (de) Verfahren zur herstellung von zwischenprodukten, die für die herstellung von retroviral-protease hemmenden verbindungen verwendbar sind
ATE46190T1 (de) Gerbstoff und verfahren zu seiner herstellung.
ATE139765T1 (de) Verfahren zur herstellung von halogenanthranilsäuren
ATE469141T1 (de) Verfahren zur herstellung von substituierten thiophensulfonylisocyanaten
DE50309092D1 (de) Verfahren zur herstellung von palladium(0)-haltigen verbindungen
DE502005006902D1 (de) Verfahren zur herstellung von amino- oder hydroxybenzonitrilen
ATE290539T1 (de) Verfahren zur herstellung von di tert.-butyl-cis- 1-propenylphosphonat
DE69812858D1 (de) Verfahren zur Herstellung von (R)-3-Hydroxy-4-Butyrolacton, nützlich für die Herstellung von (R)-Carnitin
DE60230740D1 (de) Unkatalysierte additionsreaktionen
DE602005004834D1 (de) Ein verbessertes Verfahren für die Synthese von Methylphenidaten und Zwischenprodukten
ATE352616T1 (de) Verfahren zur herstellung von zirkulären mutierten und/oder chimären polynukleotiden

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties