DK1828381T3 - Templatedirigeret split-and-mix-syntese af småmolekylebiblioteker - Google Patents

Templatedirigeret split-and-mix-syntese af småmolekylebiblioteker

Info

Publication number
DK1828381T3
DK1828381T3 DK05806601T DK05806601T DK1828381T3 DK 1828381 T3 DK1828381 T3 DK 1828381T3 DK 05806601 T DK05806601 T DK 05806601T DK 05806601 T DK05806601 T DK 05806601T DK 1828381 T3 DK1828381 T3 DK 1828381T3
Authority
DK
Denmark
Prior art keywords
molecule
oligonucleotide
template
small molecule
reaction wells
Prior art date
Application number
DK05806601T
Other languages
English (en)
Inventor
Peter Birk Rasmussen
Original Assignee
Peter Birk Rasmussen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36407493&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1828381(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Peter Birk Rasmussen filed Critical Peter Birk Rasmussen
Application granted granted Critical
Publication of DK1828381T3 publication Critical patent/DK1828381T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK05806601T 2004-11-22 2005-11-22 Templatedirigeret split-and-mix-syntese af småmolekylebiblioteker DK1828381T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200401809 2004-11-22
PCT/DK2005/000747 WO2006053571A2 (en) 2004-11-22 2005-11-22 Template directed split and mix systhesis of small molecule libraries

Publications (1)

Publication Number Publication Date
DK1828381T3 true DK1828381T3 (da) 2009-02-23

Family

ID=36407493

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05806601T DK1828381T3 (da) 2004-11-22 2005-11-22 Templatedirigeret split-and-mix-syntese af småmolekylebiblioteker

Country Status (6)

Country Link
US (8) US8168381B2 (da)
EP (1) EP1828381B1 (da)
AT (1) ATE420170T1 (da)
DE (1) DE602005012319D1 (da)
DK (1) DK1828381T3 (da)
WO (1) WO2006053571A2 (da)

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DE602004019764D1 (de) 2003-03-20 2009-04-16 Nuevolution As Ligationsvermittelnde codierung von kleinen molekülen
WO2005026387A1 (en) 2003-09-18 2005-03-24 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
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DE602005017370D1 (de) 2004-03-22 2009-12-10 Nuevolution As Ligationscodierung unter verwendung von oligonukleotidbausteinen
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ATE490318T1 (de) 2005-12-01 2010-12-15 Nuevolution As Enzymvermittelnde kodierungsmethoden für eine effiziente synthese von grossen bibliotheken
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US11124791B2 (en) 2015-09-14 2021-09-21 Arizona Board Of Regents On Behalf Of Arizona State University Generating recombinant affinity reagents with arrayed targets
WO2017218293A1 (en) 2016-06-16 2017-12-21 Richard Edward Watts Oligonucleotide directed and recorded combinatorial synthesis of encoded probe molecules
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DK1828381T3 (da) * 2004-11-22 2009-02-23 Peter Birk Rasmussen Templatedirigeret split-and-mix-syntese af småmolekylebiblioteker

Also Published As

Publication number Publication date
WO2006053571A2 (en) 2006-05-26
US20150126381A1 (en) 2015-05-07
WO2006053571A3 (en) 2006-08-17
US20150203841A1 (en) 2015-07-23
US20140235509A1 (en) 2014-08-21
US20090209430A1 (en) 2009-08-20
EP1828381B1 (en) 2009-01-07
DE602005012319D1 (de) 2009-02-26
US20130237459A1 (en) 2013-09-12
EP1828381A2 (en) 2007-09-05
US20140066336A1 (en) 2014-03-06
US20180251756A1 (en) 2018-09-06
ATE420170T1 (de) 2009-01-15
US8168381B2 (en) 2012-05-01
US20180163199A1 (en) 2018-06-14
US8951728B2 (en) 2015-02-10

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