ATE445010T1 - Stellenspezifisches system zur erstellung vielfältiger proteinsequenzen - Google Patents
Stellenspezifisches system zur erstellung vielfältiger proteinsequenzenInfo
- Publication number
- ATE445010T1 ATE445010T1 AT05804058T AT05804058T ATE445010T1 AT E445010 T1 ATE445010 T1 AT E445010T1 AT 05804058 T AT05804058 T AT 05804058T AT 05804058 T AT05804058 T AT 05804058T AT E445010 T1 ATE445010 T1 AT E445010T1
- Authority
- AT
- Austria
- Prior art keywords
- site
- nucleic acid
- protein sequences
- specific system
- diverse protein
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 4
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1024—In vivo mutagenesis using high mutation rate "mutator" host strains by inserting genetic material, e.g. encoding an error prone polymerase, disrupting a gene for mismatch repair
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Ecology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59861704P | 2004-08-03 | 2004-08-03 | |
| PCT/US2005/027625 WO2006015370A2 (en) | 2004-08-03 | 2005-08-03 | Site specific system for generating diversity protein sequences |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE445010T1 true ATE445010T1 (de) | 2009-10-15 |
Family
ID=35787926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05804058T ATE445010T1 (de) | 2004-08-03 | 2005-08-03 | Stellenspezifisches system zur erstellung vielfältiger proteinsequenzen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7585957B2 (de) |
| EP (1) | EP1773995B1 (de) |
| JP (1) | JP2008508879A (de) |
| CN (1) | CN101090967A (de) |
| AT (1) | ATE445010T1 (de) |
| AU (1) | AU2005267719B2 (de) |
| CA (1) | CA2575533C (de) |
| DE (1) | DE602005017042D1 (de) |
| WO (1) | WO2006015370A2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7749694B2 (en) * | 2004-12-31 | 2010-07-06 | The Regents Of The University Of California | C-type lectin fold as a scaffold for massive sequence variation |
| DK2021358T3 (da) * | 2006-05-15 | 2012-07-16 | Avidbiotics Corp | Modificerede bakteriociner og fremgangsmåder til anvendelse af disse |
| US8445639B2 (en) | 2006-05-15 | 2013-05-21 | Avidbiotics Corporation | Recombinant bacteriophage and methods for their use |
| US7700729B2 (en) | 2006-05-15 | 2010-04-20 | Avidbiotics Corporation | Modified bacteriocins and methods for their use |
| MX2009010549A (es) | 2007-03-30 | 2010-03-15 | Univ New York State Res Found | Virus atenuados utiles para vacunas. |
| US8877201B2 (en) | 2007-10-25 | 2014-11-04 | Wake Forest University Health Sciences | Bordetella outer-membrane protein antigens and methods of making and using the same |
| WO2012091756A1 (en) | 2010-12-30 | 2012-07-05 | Avidbiotics Corp. | Non-natural mic proteins |
| US9115354B2 (en) | 2010-05-27 | 2015-08-25 | Avidbiotics Corp. | Diffocins and methods of use thereof |
| ES2622280T3 (es) | 2010-05-27 | 2017-07-06 | Avidbiotics Corp. | Difocinas y métodos de utilización de las mismas |
| KR20150127266A (ko) | 2013-03-14 | 2015-11-16 | 아비드바이오틱스 코포레이션 | 디포신류 및 이들의 사용 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6165718A (en) * | 1996-01-10 | 2000-12-26 | Novo Nordisk A/S Novo Alle | Method for in vivo production of a mutant library in cells |
| AU2002363997A1 (en) * | 2001-12-14 | 2003-06-30 | Yale University | Intracellular generation of single-stranded dna |
| AU2003233734C1 (en) | 2002-06-05 | 2011-01-20 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food | Retrons for gene targeting |
| WO2004020627A2 (en) | 2002-08-29 | 2004-03-11 | Andreas Beck | Improved dna and proteins |
-
2005
- 2005-08-03 US US11/197,219 patent/US7585957B2/en active Active
- 2005-08-03 CA CA2575533A patent/CA2575533C/en not_active Expired - Fee Related
- 2005-08-03 AT AT05804058T patent/ATE445010T1/de not_active IP Right Cessation
- 2005-08-03 DE DE602005017042T patent/DE602005017042D1/de not_active Expired - Lifetime
- 2005-08-03 CN CNA2005800329446A patent/CN101090967A/zh active Pending
- 2005-08-03 JP JP2007524959A patent/JP2008508879A/ja active Pending
- 2005-08-03 WO PCT/US2005/027625 patent/WO2006015370A2/en not_active Ceased
- 2005-08-03 AU AU2005267719A patent/AU2005267719B2/en not_active Ceased
- 2005-08-03 EP EP05804058A patent/EP1773995B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005267719B2 (en) | 2010-12-23 |
| WO2006015370A2 (en) | 2006-02-09 |
| JP2008508879A (ja) | 2008-03-27 |
| US20060121450A1 (en) | 2006-06-08 |
| US7585957B2 (en) | 2009-09-08 |
| DE602005017042D1 (de) | 2009-11-19 |
| EP1773995B1 (de) | 2009-10-07 |
| AU2005267719A1 (en) | 2006-02-09 |
| WO2006015370A3 (en) | 2006-08-17 |
| CA2575533A1 (en) | 2006-02-09 |
| CN101090967A (zh) | 2007-12-19 |
| EP1773995A2 (de) | 2007-04-18 |
| CA2575533C (en) | 2014-11-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |