ATE401574T1 - Analyse zirkulierender tumorzellen, fragmente und trümmer - Google Patents
Analyse zirkulierender tumorzellen, fragmente und trümmerInfo
- Publication number
- ATE401574T1 ATE401574T1 AT02761478T AT02761478T ATE401574T1 AT E401574 T1 ATE401574 T1 AT E401574T1 AT 02761478 T AT02761478 T AT 02761478T AT 02761478 T AT02761478 T AT 02761478T AT E401574 T1 ATE401574 T1 AT E401574T1
- Authority
- AT
- Austria
- Prior art keywords
- analysis
- damage
- debris
- fragments
- vitro
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/549—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic with antigen or antibody entrapped within the carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31415101P | 2001-08-23 | 2001-08-23 | |
| US36962802P | 2002-04-03 | 2002-04-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE401574T1 true ATE401574T1 (de) | 2008-08-15 |
Family
ID=26979228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02761478T ATE401574T1 (de) | 2001-08-23 | 2002-08-23 | Analyse zirkulierender tumorzellen, fragmente und trümmer |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP1425383A4 (de) |
| JP (3) | JP2005501236A (de) |
| KR (2) | KR20040030984A (de) |
| CN (2) | CN1596265A (de) |
| AT (1) | ATE401574T1 (de) |
| AU (2) | AU2008288601B2 (de) |
| BR (2) | BR0212125A (de) |
| CA (2) | CA2457891C (de) |
| DE (1) | DE60227678D1 (de) |
| IL (2) | IL160209A0 (de) |
| WO (2) | WO2003018757A2 (de) |
Families Citing this family (112)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7863012B2 (en) | 2004-02-17 | 2011-01-04 | Veridex, Llc | Analysis of circulating tumor cells, fragments, and debris |
| CA2457891C (en) * | 2001-08-23 | 2019-10-01 | Immunivest Corporation | Method of preservation of circulating tumor cells |
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| MXPA04011129A (es) | 2002-05-13 | 2005-02-17 | Becton Dickinson Co | Sistema de recoleccion de muestra de inhibidor de proteasa. |
| ES2375724T3 (es) | 2002-09-27 | 2012-03-05 | The General Hospital Corporation | Dispositivo microflu�?dico para seperación de células y sus usos. |
| EP1413874A1 (de) | 2002-10-16 | 2004-04-28 | Streck Laboratories, Inc. | Verfahren und Vorrichtung zum Sammeln und Konservieren von Zellen für die Analyse |
| EP1597353B1 (de) | 2003-02-27 | 2010-11-24 | Veridex, LLC | ZIRKULIERENDE TUMORZELLEN (CTC's): FRÜHE BEURTEILUNG VON TIME-TO-PROGRESSION, ÜBERLEBEN UND ANSPRECHEN AUF THERAPIE BEI PATIENTEN MIT METASTASIERTEM KREBS |
| WO2005028663A2 (en) * | 2003-09-18 | 2005-03-31 | Immunivest Corporation | Operator independent programmable sample preparation and analysis system |
| JP2008533487A (ja) * | 2005-03-14 | 2008-08-21 | イムニベスト・コーポレイション | 循環腫瘍細胞を用いる転移性乳癌患者の療法中の各追跡期間ポイントでの無増悪および全生存を予測する方法 |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| US20080038725A1 (en) | 2005-06-20 | 2008-02-14 | Yuling Luo | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US8337755B2 (en) | 2006-03-13 | 2012-12-25 | Veridex, Llc | Operator independent programmable sample preparation and analysis system |
| CA2653745C (en) | 2006-06-02 | 2013-11-19 | Pfizer Products Inc. | Circulating tumor cell assay |
| US8372584B2 (en) | 2006-06-14 | 2013-02-12 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
| EP2029779A4 (de) | 2006-06-14 | 2010-01-20 | Living Microsystems Inc | Verwendung hoch paralleler snp-genotypisierung zur fötalen diagnose |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| CN101583722A (zh) | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | 从生物学样品检测稀有细胞的方法和组合物 |
| HUE028487T2 (en) * | 2007-02-27 | 2016-12-28 | Sentoclone Int Ab | Multiplex detection of tumour cells using a panel of agents binding to extracellular markers |
| US8003314B2 (en) | 2007-04-16 | 2011-08-23 | Diagnostic Hybrids, Inc. | Methods for direct fluorescent antibody virus detection in liquids |
| US20120202189A1 (en) * | 2007-04-16 | 2012-08-09 | Diagnostic Hybrids, Inc. | Rapid, semi-automated method to detect respiratory virus infected cells in direct specimens |
| US7828968B2 (en) | 2007-08-30 | 2010-11-09 | Veridex, Llc | Method and apparatus for imaging target components in a biological sample using permanent magnets |
| US8110101B2 (en) | 2007-08-30 | 2012-02-07 | Veridex, Llc | Method and apparatus for imaging target components in a biological sample using permanent magnets |
| US8071395B2 (en) | 2007-12-12 | 2011-12-06 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and apparatus for magnetic separation of cells |
| SMT201700149T1 (it) | 2008-09-20 | 2017-05-08 | Univ Leland Stanford Junior | Diagnosi non invasiva di aneuploidia fetale mediante sequenziamento |
| US11634747B2 (en) | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| ES2649572T3 (es) | 2009-02-18 | 2018-01-12 | Streck Inc. | Conservación de ácidos nucleicos fuera de las células |
| WO2011038403A1 (en) | 2009-09-28 | 2011-03-31 | Yuling Luo | Methods of detecting nucleic acid sequences with high specificity |
| CN107422127A (zh) * | 2009-10-21 | 2017-12-01 | 斯克里普斯研究所 | 用非稀有细胞检测稀有细胞的方法 |
| EP2529030B1 (de) | 2010-01-29 | 2019-03-13 | Advanced Cell Diagnostics, Inc. | Verfahren zum in situ nachweis von nukleinsäuren |
| WO2011099565A1 (ja) * | 2010-02-10 | 2011-08-18 | シスメックス株式会社 | 血液中癌細胞の検出方法及びそれに用いるプログラム |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| AU2011255641A1 (en) | 2010-05-18 | 2012-12-06 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US10179937B2 (en) | 2014-04-21 | 2019-01-15 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12545960B2 (en) | 2010-05-18 | 2026-02-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| DE102010020785A1 (de) * | 2010-05-18 | 2011-11-24 | Siemens Aktiengesellschaft | Vorrichtung und Verfahren zum Erkennen von magnetisch markierten Mikroobjekten |
| CA2821906C (en) | 2010-12-22 | 2020-08-25 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| CA2824387C (en) | 2011-02-09 | 2019-09-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20120252038A1 (en) * | 2011-04-01 | 2012-10-04 | Chianese David A | Steroid receptor assays |
| EP2704740B1 (de) | 2011-05-04 | 2016-10-05 | Streck, Inc. | Inaktiviertes schweinegrippe-virus und verfahren zu seiner herstellung |
| US20140295426A1 (en) * | 2011-07-28 | 2014-10-02 | Veridex Llc | Methods for Diagnosing Cancer by Characterization of Tumor Cells Associated with Pleural or Serous Fluids |
| EP4397770A1 (de) | 2011-09-26 | 2024-07-10 | PreAnalytiX GmbH | Stabilisierung und isolierung extrazellulärer nukleinsäuren |
| US11021733B2 (en) | 2011-09-26 | 2021-06-01 | Qiagen Gmbh | Stabilization and isolation of extracellular nucleic acids |
| US10676780B2 (en) | 2011-09-26 | 2020-06-09 | Qiagen Gmbh | Stabilisation and isolation of extracellular nucleic acids |
| KR102037891B1 (ko) * | 2012-03-09 | 2019-10-30 | 한국전자통신연구원 | 다중 분리 장치 및 혈중 암세포 분리 방법 |
| US20150148212A1 (en) | 2012-05-10 | 2015-05-28 | Konica Minolta, Inc. | Process for removing red blood cells and centrifugal tube for blood collection |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| CA2884915C (en) | 2012-09-25 | 2022-05-17 | Qiagen Gmbh | Stabilisation of biological samples |
| US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
| CN110186835B (zh) | 2013-03-15 | 2022-05-31 | Gpb科学有限公司 | 颗粒的片上微流体处理 |
| CN105247042B (zh) | 2013-03-15 | 2021-06-11 | 普林斯顿大学理事会 | 用于高通量纯化的方法和设备 |
| CN105283550A (zh) | 2013-03-18 | 2016-01-27 | 凯杰有限公司 | 生物样品的稳定化 |
| CN105121643A (zh) * | 2013-03-18 | 2015-12-02 | 凯杰有限公司 | 细胞外核酸的稳定化和分离 |
| CA2917912C (en) | 2013-07-24 | 2019-09-17 | Streck, Inc. | Compositions and methods for stabilizing circulating tumor cells |
| CA2928779A1 (en) * | 2013-10-21 | 2015-04-30 | The General Hospital Corporation | Methods relating to circulating tumor cell clusters and the treatment of cancer |
| WO2015112955A1 (en) | 2014-01-27 | 2015-07-30 | Epic Sciences, Inc. | Circulating tumor cell diagnostics for prostate cancer biomarkers |
| WO2015127008A1 (en) | 2014-02-21 | 2015-08-27 | Epic Sciences, Inc. | Methods for analyzing rare circulating cells |
| JP6664332B2 (ja) * | 2014-03-18 | 2020-03-13 | キアゲン ゲーエムベーハー | 細胞外核酸の安定化および単離 |
| CN103940997B (zh) * | 2014-03-21 | 2017-01-04 | 上海柏慧康生物科技有限公司 | 一种乳腺癌循环肿瘤细胞检测系统及试剂盒 |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| CN103980365A (zh) * | 2014-06-03 | 2014-08-13 | 国家纳米科学中心 | 一种表面固载炭疽致死因子的磁性纳米粒子、其制备方法及用途 |
| US20180173846A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| WO2016004308A1 (en) * | 2014-07-02 | 2016-01-07 | Siemens Healthcare Diagnostics Inc. | Selective nucleic acid separation |
| WO2016137915A1 (en) * | 2015-02-24 | 2016-09-01 | Siemens Healthcare Diagnostics Inc. | Prefixation for increased rare cell recovery |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| DK3294906T3 (en) | 2015-05-11 | 2024-08-05 | Natera Inc | Methods for determining ploidy |
| CA2936167A1 (en) * | 2015-07-15 | 2017-01-15 | Streck, Inc. | Method and device for stabilizing of proteins |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| JP6617495B2 (ja) * | 2015-09-18 | 2019-12-11 | 東ソー株式会社 | 腫瘍細胞の検出方法 |
| WO2017079212A1 (en) * | 2015-11-04 | 2017-05-11 | Axon Dx, Llc | Cell detection, capture, analysis, aggregation, and output methods and apparatus |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| CA3005694A1 (en) | 2015-11-20 | 2017-05-26 | Qiagen Gmbh | Method of preparing sterilized compositions for stabilization of extracellular nucleic acids |
| CN105372109A (zh) * | 2015-12-15 | 2016-03-02 | 苏州药明康德新药开发股份有限公司 | 添加稳定剂的生物基质的制备方法 |
| PL3422848T3 (pl) * | 2016-03-04 | 2025-05-26 | Menarini Silicon Biosystems S.P.A. | Konserwowanie składników komórkowych z komórek za pomocą środka konserwującego |
| CA3014773C (en) | 2016-03-07 | 2025-11-18 | Father Flanagan's Boys' Home Doing Business As Boys Town National Research Hospital | NON-INVASIVE MOLECULAR WITRS |
| WO2017181202A2 (en) | 2016-04-15 | 2017-10-19 | Natera, Inc. | Methods for lung cancer detection |
| JP2017219479A (ja) | 2016-06-09 | 2017-12-14 | 住友電気工業株式会社 | 微小粒子計測装置及び分析方法 |
| EP3491381B1 (de) | 2016-07-29 | 2025-09-24 | Streck LLC | Suspensionszusammensetzung zur kontrolle einer hämatologischen analyse |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| KR102476709B1 (ko) | 2016-11-21 | 2022-12-09 | 나노스트링 테크놀로지스, 인크. | 화학적 조성물 및 이것을 사용하는 방법 |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| ES2909392T3 (es) | 2017-08-02 | 2022-05-06 | Sarstedt Ag & Co Kg | Procedimiento y composición para la estabilización de ácidos nucleicos libres de células y células |
| JP7393328B2 (ja) | 2017-09-01 | 2023-12-06 | ジーピービー・サイエンティフィック・インコーポレイテッド | マイクロ流体を使用した治療的に活性な細胞を調製する方法 |
| HUE068517T2 (hu) * | 2017-10-19 | 2024-12-28 | Streck Llc | A hemolízis és a véralvadás szabályozására, valamint az extracelluláris vezikulák stabilizálására szolgáló készítmények |
| CA3085933A1 (en) | 2017-12-14 | 2019-06-20 | Tai Diagnostics, Inc. | Assessing graft suitability for transplantation |
| EP3781714B1 (de) | 2018-04-14 | 2026-01-07 | Natera, Inc. | Verfahren zur krebserkennung und -überwachung durch personalisierte detektion zirkulierender tumor-dna |
| EP3794146B1 (de) | 2018-05-14 | 2025-12-10 | Bruker Spatial Biology, Inc. | Verfahren zur erkennung einer zuvor bestimmten nukleotidesequenz |
| JP7334468B2 (ja) * | 2018-05-29 | 2023-08-29 | 東ソー株式会社 | 血液試料保存剤 |
| JP7036670B2 (ja) | 2018-05-31 | 2022-03-15 | アークレイ株式会社 | 血液中の稀少細胞検査、該検査ための血液処理方法及び採血管 |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| CN108865976B (zh) * | 2018-07-19 | 2022-06-28 | 复旦大学附属中山医院 | 一种离散汲取收集外泌体(exosome)的方法及试剂 |
| CN110250159A (zh) * | 2019-05-28 | 2019-09-20 | 天津中科生物科技有限公司 | 一种细胞保护液及其制备方法和应用 |
| US12305235B2 (en) | 2019-06-06 | 2025-05-20 | Natera, Inc. | Methods for detecting immune cell DNA and monitoring immune system |
| KR20240168912A (ko) * | 2022-03-25 | 2024-12-02 | 세키스이 메디칼 가부시키가이샤 | 순환 종양 세포 분리 키트, 순환 종양 세포 분리 용기 및 순환 종양 세포의 분리 방법 |
| WO2024238350A1 (en) * | 2023-05-12 | 2024-11-21 | The Children's Medical Center Corporation | Single-cell regulatory multi-omics with deep mitochondrial mutation profiling (redeem) |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4040785A (en) * | 1976-10-18 | 1977-08-09 | Technicon Instruments Corporation | Lysable blood preservative composition |
| US4320111A (en) * | 1977-06-14 | 1982-03-16 | American Home Products Corporation | Immunologic compositions methods of preparation and use |
| FR2475737A1 (fr) * | 1980-02-07 | 1981-08-14 | Pasteur Institut | Perfectionnements apportes aux procedes de conservation d'hematies par lyophilisation en vue de leur utilisation dans des reactions d'hemagglutination et hematies non agglutinables spontanement obtenues par ce procede |
| US4404181A (en) * | 1981-10-15 | 1983-09-13 | Cambridge Chemical Products, Inc. | Extended-life tissue fixative composition and method of using the same |
| FR2523810B1 (fr) * | 1982-03-23 | 1988-11-25 | Carpentier Alain | Tissu biologique greffable et procede pour sa preparation |
| FR2528848A1 (fr) * | 1982-06-16 | 1983-12-23 | Sanofi Sa | Nouveau derive de thieno-pyridone, son procede de preparation et son application therapeutique |
| EP0156537A3 (de) * | 1984-03-02 | 1987-05-13 | Board Of Regents University Of Texas System | Biologische magnetische Flüssigkeiten |
| US4654312A (en) * | 1984-05-14 | 1987-03-31 | Becton, Dickinson And Company | Lysing agent for analysis of peripheral blood cells |
| US4788139A (en) * | 1987-08-06 | 1988-11-29 | Streck Laboratories, Inc. | Platelet aggregation reagent, reagent container and method of determining platelet aggregation in EDTA-anticoagulated blood |
| US5385707A (en) * | 1988-12-28 | 1995-01-31 | Stefan Miltenyi | Metal matrices for use in high gradient magnetic separation of biological materials and method for coating the same |
| US5698271A (en) * | 1989-08-22 | 1997-12-16 | Immunivest Corporation | Methods for the manufacture of magnetically responsive particles |
| US5849517A (en) * | 1991-05-08 | 1998-12-15 | Streck Laboratories, Inc. | Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same |
| EP0627879A1 (de) * | 1991-09-20 | 1994-12-14 | CAMIENER, Gerald, W. | Verfahren und zusammensetzungen mit einer aldehydstabilisierenden lösung |
| WO1994018828A1 (en) * | 1993-02-25 | 1994-09-01 | Abbott Laboratories | Multipurpose reagent system for rapid lysis of whole blood samples |
| US6190870B1 (en) * | 1995-08-28 | 2001-02-20 | Amcell Corporation | Efficient enrichment and detection of disseminated tumor cells |
| GB2313288B (en) * | 1996-05-24 | 2000-07-12 | North Gen Hospital Nhs Trust | Specimen collection fluid |
| US6197523B1 (en) * | 1997-11-24 | 2001-03-06 | Robert A. Levine | Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood |
| US6670197B2 (en) * | 1997-11-24 | 2003-12-30 | David L. Rimm | Method for assaying whole blood for the presence or absence of circulating cancer or other target cell fragments |
| BR9907852A (pt) * | 1998-02-12 | 2000-10-24 | Immunivest Corp | Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes |
| WO2000047998A1 (en) * | 1999-02-10 | 2000-08-17 | Cell Works Inc. | Class characterization of circulating cancer cells isolated from body fluids and methods of use |
| EP1221053A4 (de) * | 1999-09-13 | 2004-12-22 | Neil H Bander | Verfahren zur isolierung von prostatischen epithelzellen aus sperma |
| CA2457891C (en) * | 2001-08-23 | 2019-10-01 | Immunivest Corporation | Method of preservation of circulating tumor cells |
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- 2002-08-23 BR BR0212124-7A patent/BR0212124A/pt not_active Application Discontinuation
- 2002-08-23 DE DE60227678T patent/DE60227678D1/de not_active Expired - Lifetime
- 2002-08-23 KR KR10-2004-7002572A patent/KR20040030984A/ko not_active Withdrawn
- 2002-08-23 EP EP02761478A patent/EP1425294B2/de not_active Expired - Lifetime
- 2002-08-23 KR KR10-2004-7002473A patent/KR20040053115A/ko not_active Withdrawn
- 2002-08-23 IL IL16020902A patent/IL160209A0/xx unknown
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| CA2457894C (en) | 2014-07-08 |
| CA2457891A1 (en) | 2003-03-06 |
| IL160210A0 (en) | 2004-07-25 |
| CA2457894A1 (en) | 2003-03-06 |
| AU2008288601B2 (en) | 2012-05-31 |
| CA2457891C (en) | 2019-10-01 |
| WO2003019141A2 (en) | 2003-03-06 |
| KR20040053115A (ko) | 2004-06-23 |
| EP1425383A4 (de) | 2005-11-09 |
| WO2003018757A2 (en) | 2003-03-06 |
| EP1425294B2 (de) | 2012-12-12 |
| WO2003018757A3 (en) | 2003-09-12 |
| IL160209A0 (en) | 2004-07-25 |
| JP2005502863A (ja) | 2005-01-27 |
| EP1425294A4 (de) | 2005-11-16 |
| KR20040030984A (ko) | 2004-04-09 |
| JP2009109514A (ja) | 2009-05-21 |
| JP2005501236A (ja) | 2005-01-13 |
| AU2009200013B2 (en) | 2012-03-08 |
| DE60227678D1 (de) | 2008-08-28 |
| EP1425383A2 (de) | 2004-06-09 |
| WO2003019141A3 (en) | 2004-04-01 |
| CN1596265A (zh) | 2005-03-16 |
| BR0212125A (pt) | 2005-06-28 |
| EP1425294B1 (de) | 2008-07-16 |
| BR0212124A (pt) | 2004-07-20 |
| AU2008288601A1 (en) | 2009-04-02 |
| CN1571634A (zh) | 2005-01-26 |
| EP1425294A2 (de) | 2004-06-09 |
| AU2009200013A1 (en) | 2009-02-05 |
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