ATE389645T1 - Verfahren zur herstellung von citalopram - Google Patents

Verfahren zur herstellung von citalopram

Info

Publication number
ATE389645T1
ATE389645T1 AT01931469T AT01931469T ATE389645T1 AT E389645 T1 ATE389645 T1 AT E389645T1 AT 01931469 T AT01931469 T AT 01931469T AT 01931469 T AT01931469 T AT 01931469T AT E389645 T1 ATE389645 T1 AT E389645T1
Authority
AT
Austria
Prior art keywords
producing citalopram
citalopram
producing
Prior art date
Application number
AT01931469T
Other languages
German (de)
English (en)
Inventor
Hans Petersen
Robert Dancer
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE389645T1 publication Critical patent/ATE389645T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT01931469T 2000-05-12 2001-05-10 Verfahren zur herstellung von citalopram ATE389645T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200000783 2000-05-12

Publications (1)

Publication Number Publication Date
ATE389645T1 true ATE389645T1 (de) 2008-04-15

Family

ID=8159493

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01931469T ATE389645T1 (de) 2000-05-12 2001-05-10 Verfahren zur herstellung von citalopram

Country Status (30)

Country Link
US (1) US6660873B2 (sk)
EP (1) EP1296970B1 (sk)
JP (1) JP2003532721A (sk)
CN (1) CN100422166C (sk)
AR (1) AR032455A1 (sk)
AT (1) ATE389645T1 (sk)
AU (2) AU5823901A (sk)
BG (1) BG65820B1 (sk)
BR (1) BR0110996A (sk)
CA (1) CA2408292C (sk)
CZ (1) CZ20024065A3 (sk)
DE (1) DE60133280T2 (sk)
DK (1) DK1296970T3 (sk)
EA (1) EA005674B1 (sk)
ES (1) ES2301541T3 (sk)
HK (1) HK1056171A1 (sk)
HR (1) HRP20020881A2 (sk)
HU (1) HUP0301942A2 (sk)
IL (2) IL152645A0 (sk)
IS (1) IS2586B (sk)
MX (1) MXPA02011125A (sk)
NO (1) NO327963B1 (sk)
NZ (1) NZ522475A (sk)
PL (1) PL358144A1 (sk)
PT (1) PT1296970E (sk)
SI (1) SI1296970T1 (sk)
SK (1) SK287035B6 (sk)
UA (1) UA72039C2 (sk)
WO (1) WO2001085712A1 (sk)
ZA (1) ZA200208973B (sk)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2195554T5 (es) 1999-04-14 2010-02-02 H. Lundbeck A/S Metodo para la preparacion de citalopram.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
US6433196B1 (en) * 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
PL357022A1 (en) 2000-03-13 2004-07-12 H.Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IN192057B (sk) * 2001-07-19 2004-02-14 Ranbaxy Lab Ltd
WO2004085416A1 (en) * 2003-03-24 2004-10-07 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
AU2003278409A1 (en) * 2003-10-28 2005-05-19 Krishnaji Upadhye Bhargav Improved process for the manufacture of citalopram hydrobromide
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
KR101166280B1 (ko) 2004-08-23 2013-11-27 썬 파마 글로벌 에프제트이 시탈로프램 및 에난티오머의 제조 방법

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (sk) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
CZ291440B6 (cs) 1997-07-08 2003-03-12 H. Lundbeck A/S Způsob výroby citalopramu
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
WO1998019512A2 (en) * 1997-11-11 1998-05-14 H. Lundbeck A/S Method for the preparation of citalopram
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
PL203275B1 (pl) 1998-12-23 2009-09-30 Lundbeck & Co As H Sposób wytwarzania 5-cyjanoftalidu
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
ES2195554T5 (es) 1999-04-14 2010-02-02 H. Lundbeck A/S Metodo para la preparacion de citalopram.
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991486A1 (it) 1999-07-06 2001-01-06 Vis Farmaceutici S P A Processo per la sintesi di citalopram
TR200101874T1 (tr) 1999-10-25 2002-02-21 H. Lundbeck A/S Sitalopram hazırlanması için yöntem
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
EP1246812B1 (en) 1999-12-28 2004-03-17 H. Lundbeck A/S Method for the preparation of citalopram
HUP0203840A3 (en) 1999-12-30 2005-02-28 Lundbeck & Co As H Method for the preparation of citalopram
ATE252570T1 (de) 2000-01-14 2003-11-15 Lundbeck & Co As H Verfahren zur herstellung von 5-cyanophthalid
IT1317729B1 (it) 2000-01-18 2003-07-15 Norpharma S P A Procedimento per la preparazione della 5-carbossiftalide.
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
GB2357762B (en) 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
KR20020080481A (ko) 2000-03-13 2002-10-23 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조 방법
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
PL357022A1 (en) 2000-03-13 2004-07-12 H.Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
DK1265882T3 (da) 2000-03-14 2004-06-01 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
TR200202168T2 (tr) 2000-03-16 2002-12-23 H. Lundbeck A/S 5-Siyano-1-(4-Florofenil)-1,3-Dihidroizobenzofuranların preparasyon metodu
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
BR0106976A (pt) 2000-07-06 2002-07-23 Lundbeck & Co As H Método para a preparação de citalopram
FI20011621A (fi) 2000-08-18 2002-02-19 Lundbeck & Co As H Menetelmä sitalopraamin valmistamiseksi
EA003581B1 (ru) 2000-12-22 2003-06-26 Х.Лундбекк А/С Способ получения чистого циталопрама
WO2001047877A2 (en) 2000-12-28 2001-07-05 H. Lundbeck A/S Process for the preparation of pure citalopram

Also Published As

Publication number Publication date
BR0110996A (pt) 2003-03-18
AU2001258239B2 (en) 2005-12-08
WO2001085712A1 (en) 2001-11-15
EA005674B1 (ru) 2005-04-28
EP1296970B1 (en) 2008-03-19
NO20025423L (no) 2002-11-12
PL358144A1 (en) 2004-08-09
HRP20020881A2 (en) 2004-12-31
BG65820B1 (bg) 2010-01-29
CA2408292A1 (en) 2001-11-15
SK287035B6 (sk) 2009-10-07
DE60133280D1 (de) 2008-04-30
PT1296970E (pt) 2008-06-11
IS6605A (is) 2002-10-31
US20030134895A1 (en) 2003-07-17
US6660873B2 (en) 2003-12-09
ES2301541T3 (es) 2008-07-01
EA200201211A1 (ru) 2003-04-24
CZ20024065A3 (cs) 2003-03-12
NZ522475A (en) 2004-09-24
JP2003532721A (ja) 2003-11-05
CA2408292C (en) 2009-11-10
AU5823901A (en) 2001-11-20
ZA200208973B (en) 2003-11-05
DE60133280T2 (de) 2009-04-16
UA72039C2 (en) 2005-01-17
CN100422166C (zh) 2008-10-01
IS2586B (is) 2010-02-15
SK17542002A3 (sk) 2003-04-01
DK1296970T3 (da) 2008-07-14
MXPA02011125A (es) 2003-03-10
HUP0301942A2 (hu) 2003-09-29
CN1441795A (zh) 2003-09-10
BG107349A (bg) 2003-09-30
AR032455A1 (es) 2003-11-12
NO327963B1 (no) 2009-10-26
HK1056171A1 (en) 2004-02-06
EP1296970A1 (en) 2003-04-02
NO20025423D0 (no) 2002-11-12
IL152645A (en) 2009-12-24
IL152645A0 (en) 2003-06-24
SI1296970T1 (sl) 2008-08-31

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