ATE252570T1 - Verfahren zur herstellung von 5-cyanophthalid - Google Patents

Verfahren zur herstellung von 5-cyanophthalid

Info

Publication number
ATE252570T1
ATE252570T1 AT00900501T AT00900501T ATE252570T1 AT E252570 T1 ATE252570 T1 AT E252570T1 AT 00900501 T AT00900501 T AT 00900501T AT 00900501 T AT00900501 T AT 00900501T AT E252570 T1 ATE252570 T1 AT E252570T1
Authority
AT
Austria
Prior art keywords
sup
sub
cyanophthalide
alkyl
hydrogen
Prior art date
Application number
AT00900501T
Other languages
English (en)
Inventor
Hans Petersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE252570T1 publication Critical patent/ATE252570T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
AT00900501T 2000-01-14 2000-01-14 Verfahren zur herstellung von 5-cyanophthalid ATE252570T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/DK2000/000016 WO2001051477A1 (en) 2000-01-14 2000-01-14 Method for the preparation of 5-cyanophthalide

Publications (1)

Publication Number Publication Date
ATE252570T1 true ATE252570T1 (de) 2003-11-15

Family

ID=8149377

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00900501T ATE252570T1 (de) 2000-01-14 2000-01-14 Verfahren zur herstellung von 5-cyanophthalid

Country Status (27)

Country Link
US (1) US6911548B2 (de)
EP (1) EP1254129B1 (de)
JP (1) JP2003519691A (de)
KR (1) KR100660802B1 (de)
CN (1) CN1195749C (de)
AT (1) ATE252570T1 (de)
AU (1) AU3033700A (de)
CA (1) CA2397270C (de)
CZ (1) CZ20022601A3 (de)
DE (1) DE60006163T2 (de)
DK (1) DK1254129T3 (de)
EA (1) EA005134B1 (de)
ES (1) ES2206177T3 (de)
HK (1) HK1054392B (de)
HU (1) HUP0300343A2 (de)
IL (2) IL150561A0 (de)
IS (1) IS2168B (de)
IT (1) ITMI20010040A1 (de)
MX (1) MXPA02006915A (de)
NO (1) NO20023405L (de)
PL (1) PL197821B1 (de)
PT (1) PT1254129E (de)
SI (1) SI1254129T1 (de)
SK (1) SK286879B6 (de)
TR (1) TR200201783T2 (de)
UA (1) UA72569C2 (de)
WO (1) WO2001051477A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1142926C (zh) * 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
CZ20022213A3 (cs) 1999-12-28 2002-09-11 H. Lundbeck A/S Způsob výroby citalopramu
SI1246813T1 (en) 1999-12-30 2004-08-31 H. Lundbeck A/S Method for the preparation of citalopram
CZ20022601A3 (cs) 2000-01-14 2002-10-16 H. Lundbeck A/S Způsob výroby 5-kyanoftalidu
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
MXPA02008869A (es) 2000-03-13 2003-02-10 Lundbeck & Co As H Metodo para la preparacion de citalopram.
EA200200968A1 (ru) 2000-03-13 2003-02-27 Х.Лундбекк А/С Поэтапное алкилирование 5-замещенных 1-(4-фторфенил)-1,3-дигидроизобензофуранов
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
JP2003527386A (ja) 2000-03-14 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
ATE415387T1 (de) * 2002-05-15 2008-12-15 Genzyme Corp Verfahren zur herstellung von benzonitrilen und benzimidosäure-derivaten
WO2005111010A1 (en) * 2004-05-13 2005-11-24 Suven Life Sciences Ltd, An improved process for the preparation of 5-cyanophthalide
CN116022748B (zh) * 2022-12-16 2024-02-27 山东惟普新能源有限公司 一种含水双氟磺酰亚胺锂的除水方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (de) * 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) * 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) * 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) * 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
EP1015416B1 (de) 1997-07-08 2001-09-19 H. Lundbeck A/S Verfahren zur herstellung von citalopram
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
DE69714480T2 (de) 1997-11-11 2003-03-06 Lundbeck & Co As H Verfahren zur Herstellung von Citalopram
EA002977B1 (ru) * 1998-10-20 2002-12-26 Х.Лундбекк А/С Способ получения циталопрама
CN1149208C (zh) * 1998-12-23 2004-05-12 H.隆德贝克有限公司 制备5-氰基2-苯并[c]呋喃酮的方法
AR022329A1 (es) * 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
CN1142926C (zh) 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ES2169709A1 (es) * 1999-10-25 2002-07-01 Lundbeck & Co As H Metodo para la preparacion de citalopram
US6310222B1 (en) * 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AR026063A1 (es) * 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
CZ20022213A3 (cs) 1999-12-28 2002-09-11 H. Lundbeck A/S Způsob výroby citalopramu
SI1246813T1 (en) 1999-12-30 2004-08-31 H. Lundbeck A/S Method for the preparation of citalopram
CZ20022601A3 (cs) 2000-01-14 2002-10-16 H. Lundbeck A/S Způsob výroby 5-kyanoftalidu
FR2805812A1 (fr) * 2000-02-24 2001-09-07 Lundbeck & Co As H Procede de preparation du citalopram
IES20010143A2 (en) * 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IL144817A0 (en) * 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
ES2228824T3 (es) 2000-12-22 2005-04-16 H. Lundbeck A/S Metodo de preparacion de citalopram puro.
IL147162A0 (en) 2000-12-28 2002-08-14 Lundbeck & Co As H Process for the preparation of pure citalopram

Also Published As

Publication number Publication date
CN1423643A (zh) 2003-06-11
ES2206177T3 (es) 2004-05-16
MXPA02006915A (es) 2002-10-23
PL197821B1 (pl) 2008-04-30
KR20020073501A (ko) 2002-09-26
HUP0300343A2 (hu) 2003-06-28
PL356712A1 (en) 2004-06-28
TR200201783T2 (tr) 2002-12-23
CZ20022601A3 (cs) 2002-10-16
SK286879B6 (sk) 2009-07-06
IS2168B (is) 2006-11-15
EP1254129A1 (de) 2002-11-06
DK1254129T3 (da) 2004-03-29
KR100660802B1 (ko) 2006-12-26
EA200200758A1 (ru) 2002-12-26
IL150561A (en) 2007-07-04
AU3033700A (en) 2001-07-24
CA2397270C (en) 2007-08-21
ITMI20010040A1 (it) 2002-07-11
DE60006163D1 (de) 2003-11-27
JP2003519691A (ja) 2003-06-24
DE60006163T2 (de) 2004-04-15
EP1254129B1 (de) 2003-10-22
NO20023405L (no) 2002-08-30
HK1054392A1 (en) 2003-11-28
CN1195749C (zh) 2005-04-06
IL150561A0 (en) 2003-02-12
SI1254129T1 (en) 2004-02-29
NO20023405D0 (no) 2002-07-15
UA72569C2 (uk) 2005-03-15
EA005134B1 (ru) 2004-12-30
SK11662002A3 (sk) 2003-01-09
US20030013895A1 (en) 2003-01-16
HK1054392B (zh) 2005-11-18
IS6449A (is) 2002-06-28
WO2001051477A1 (en) 2001-07-19
CA2397270A1 (en) 2001-07-19
PT1254129E (pt) 2004-03-31
US6911548B2 (en) 2005-06-28

Similar Documents

Publication Publication Date Title
BG105457A (en) Method for the preparation of citalopram
ATE252570T1 (de) Verfahren zur herstellung von 5-cyanophthalid
KR970027031A (ko) 일차 또는 이차 알콜의 산화방법
EA199900301A2 (ru) Замещенные трициклические соединения
EA200500037A1 (ru) Фенилбензамиды
DE59108707D1 (de) Verfahren zur Herstellung von Oxetanonen
EA199900304A2 (ru) Замещенные трициклические соединения
EA200100297A1 (ru) Моногидрат гидробромида элетриптана
ATE275561T1 (de) Verfahren zur herstellung von pantoprazol und zwischenprodukte dieses verfahrens
DE69908909D1 (de) Verfahren zur herstellung von simvastatin und ihren derivaten
DK1204658T3 (da) Benzofurylpiperazin-serotoninagonister
ATE257832T1 (de) Verfahren zur herstellung von citalopram
DE502004002562D1 (de) Verfahren zur herstellung hochreiner polyalkylenglykole
GT199900047A (es) Procedimiento para alquilar sulfonamidas impedidas estèricamente.
ATE294168T1 (de) Herstellung von trans-kondensierte 3,3a,8,12b- tetrahydro-2h-dibenzo(3,4:6,7)cyclohepta(1,2- b)furan derivaten
PT1392672E (pt) Clorometilacao de tiofeno
HUP0300845A2 (hu) Sebgyógyulást elősegítő készítmény, eljárás az előállítására és alkalmazása
BG106846A (en) Novel heteroaryl derivatives, their preparation and use
EA200101091A1 (ru) Получение псевдомицина pseudomonas syringae
ATE210114T1 (de) Herstellung von di-tert-peroxiden
BR0017002A (pt) Método para a preparação de 5-cianoftalida
ATE260267T1 (de) Verfahren zur herstellung von c-4-deacetyltaxanen
ATE272618T1 (de) Verfahren zur herstellung von s-alkylcysteinen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1254129

Country of ref document: EP

REN Ceased due to non-payment of the annual fee