ATE294168T1 - Herstellung von trans-kondensierte 3,3a,8,12b- tetrahydro-2h-dibenzo(3,4:6,7)cyclohepta(1,2- b)furan derivaten - Google Patents
Herstellung von trans-kondensierte 3,3a,8,12b- tetrahydro-2h-dibenzo(3,4:6,7)cyclohepta(1,2- b)furan derivatenInfo
- Publication number
- ATE294168T1 ATE294168T1 AT02779576T AT02779576T ATE294168T1 AT E294168 T1 ATE294168 T1 AT E294168T1 AT 02779576 T AT02779576 T AT 02779576T AT 02779576 T AT02779576 T AT 02779576T AT E294168 T1 ATE294168 T1 AT E294168T1
- Authority
- AT
- Austria
- Prior art keywords
- trans
- preparation
- cyclohepta
- dibenzo
- tetrahydro
- Prior art date
Links
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical class C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 title 1
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 abstract 2
- 239000007795 chemical reaction product Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01204961 | 2001-12-07 | ||
| PCT/EP2002/013560 WO2003048146A1 (en) | 2001-12-07 | 2002-12-02 | PREPARATION OF TRANS-FUSED 3,3a,8,12b-TETRAHYDRO-2H-DIBENZO[3,4:6,7]CYCLOHEPTA[1,2-b]FURAN DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE294168T1 true ATE294168T1 (de) | 2005-05-15 |
Family
ID=8181460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02779576T ATE294168T1 (de) | 2001-12-07 | 2002-12-02 | Herstellung von trans-kondensierte 3,3a,8,12b- tetrahydro-2h-dibenzo(3,4:6,7)cyclohepta(1,2- b)furan derivaten |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6998494B2 (de) |
| EP (1) | EP1456193B1 (de) |
| JP (1) | JP4516752B2 (de) |
| KR (1) | KR20050044329A (de) |
| CN (1) | CN1293066C (de) |
| AT (1) | ATE294168T1 (de) |
| AU (1) | AU2002342926B2 (de) |
| BR (1) | BR0214068A (de) |
| CA (1) | CA2468038C (de) |
| DE (1) | DE60203937T2 (de) |
| ES (1) | ES2242076T3 (de) |
| HR (1) | HRP20040490A2 (de) |
| HU (1) | HUP0402152A3 (de) |
| IL (1) | IL162349A0 (de) |
| MX (1) | MXPA04005400A (de) |
| NO (1) | NO20042884L (de) |
| NZ (1) | NZ532806A (de) |
| PL (1) | PL369585A1 (de) |
| WO (1) | WO2003048146A1 (de) |
| ZA (1) | ZA200404394B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE294168T1 (de) * | 2001-12-07 | 2005-05-15 | Janssen Pharmaceutica Nv | Herstellung von trans-kondensierte 3,3a,8,12b- tetrahydro-2h-dibenzo(3,4:6,7)cyclohepta(1,2- b)furan derivaten |
| WO2005013969A1 (en) * | 2003-07-15 | 2005-02-17 | Janssen Pharmaceutica N.V. | Antipsychotic agent with socializing properties |
| WO2005121113A1 (en) * | 2004-06-14 | 2005-12-22 | Janssen Pharmaceutica N.V. | Novel tetracyclic tetrahydrofuran derivatives |
| CA2577305C (en) | 2004-08-31 | 2013-12-17 | Janssen Pharmaceutica N.V. | Process for the production of [2-(4-fluoro-benzyl)-phenyl]-acetic acid |
| RU2401257C2 (ru) | 2004-12-07 | 2010-10-10 | Янссен Фармацевтика Н.В. | Новые замещенные тетрациклические производные тетрагидрофурана, пирролидина и тетрагидротиофена |
| MX2007009092A (es) | 2005-01-27 | 2007-09-12 | Janssen Pharmaceutica Nv | Derivados de tetrahidrofurano tetraciclicos heterociclicos como inhibidores de 5ht2 en el tratamiento de trastornos del sistema nervioso central. |
| CN101228154B (zh) | 2005-06-17 | 2014-01-29 | 詹森药业有限公司 | 包含环状胺侧链的四环四氢呋喃衍生物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69720709T2 (de) * | 1996-04-12 | 2004-03-11 | Janssen Pharmaceutica N.V. | Substituierte tetracyclische tetrahydrofuranderivate |
| UA52778C2 (uk) * | 1997-10-10 | 2003-01-15 | Янссен Фармацевтика Н.В. | Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі |
| UA79248C2 (en) * | 2001-11-09 | 2007-06-11 | Janssen Pharmaceutica Nv | Mandelate salts of substituted tetracyclic tetrahydrofuran derivatives |
| ATE294168T1 (de) * | 2001-12-07 | 2005-05-15 | Janssen Pharmaceutica Nv | Herstellung von trans-kondensierte 3,3a,8,12b- tetrahydro-2h-dibenzo(3,4:6,7)cyclohepta(1,2- b)furan derivaten |
| HUP0402325A2 (hu) * | 2001-12-07 | 2005-02-28 | Janssen Pharmaceutica N.V. | Eljárás cisz-fuzionált 3,3a,8,12b-tetrahidro-2H-dibenzo [3,4:6,7] ciklohepta [1,2-b]furán-származékok előállítására |
-
2002
- 2002-12-02 AT AT02779576T patent/ATE294168T1/de not_active IP Right Cessation
- 2002-12-02 IL IL16234902A patent/IL162349A0/xx not_active IP Right Cessation
- 2002-12-02 HR HR20040490A patent/HRP20040490A2/hr not_active Application Discontinuation
- 2002-12-02 CN CNB028244885A patent/CN1293066C/zh not_active Expired - Fee Related
- 2002-12-02 MX MXPA04005400A patent/MXPA04005400A/es active IP Right Grant
- 2002-12-02 JP JP2003549337A patent/JP4516752B2/ja not_active Expired - Fee Related
- 2002-12-02 ES ES02779576T patent/ES2242076T3/es not_active Expired - Lifetime
- 2002-12-02 US US10/496,279 patent/US6998494B2/en not_active Expired - Fee Related
- 2002-12-02 BR BR0214068-3A patent/BR0214068A/pt not_active IP Right Cessation
- 2002-12-02 WO PCT/EP2002/013560 patent/WO2003048146A1/en not_active Ceased
- 2002-12-02 KR KR1020047005553A patent/KR20050044329A/ko not_active Withdrawn
- 2002-12-02 EP EP02779576A patent/EP1456193B1/de not_active Expired - Lifetime
- 2002-12-02 AU AU2002342926A patent/AU2002342926B2/en not_active Ceased
- 2002-12-02 CA CA2468038A patent/CA2468038C/en not_active Expired - Fee Related
- 2002-12-02 DE DE60203937T patent/DE60203937T2/de not_active Expired - Lifetime
- 2002-12-02 NZ NZ532806A patent/NZ532806A/en unknown
- 2002-12-02 PL PL02369585A patent/PL369585A1/xx not_active Application Discontinuation
- 2002-12-02 HU HU0402152A patent/HUP0402152A3/hu unknown
-
2004
- 2004-06-03 ZA ZA200404394A patent/ZA200404394B/en unknown
- 2004-07-07 NO NO20042884A patent/NO20042884L/no not_active Application Discontinuation
-
2005
- 2005-05-31 US US11/141,612 patent/US20050228043A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6998494B2 (en) | 2006-02-14 |
| HK1076461A1 (en) | 2006-01-20 |
| IL162349A0 (en) | 2005-11-20 |
| EP1456193A1 (de) | 2004-09-15 |
| US20050014820A1 (en) | 2005-01-20 |
| ES2242076T3 (es) | 2005-11-01 |
| DE60203937D1 (de) | 2005-06-02 |
| JP4516752B2 (ja) | 2010-08-04 |
| BR0214068A (pt) | 2004-10-13 |
| MXPA04005400A (es) | 2004-10-11 |
| CA2468038C (en) | 2011-04-26 |
| AU2002342926A1 (en) | 2003-06-17 |
| HUP0402152A3 (en) | 2007-03-28 |
| NO20042884L (no) | 2004-07-07 |
| WO2003048146A1 (en) | 2003-06-12 |
| US20050228043A1 (en) | 2005-10-13 |
| CA2468038A1 (en) | 2003-06-12 |
| HUP0402152A2 (hu) | 2005-02-28 |
| JP2005511691A (ja) | 2005-04-28 |
| CN1293066C (zh) | 2007-01-03 |
| PL369585A1 (en) | 2005-05-02 |
| AU2002342926B2 (en) | 2009-02-26 |
| NZ532806A (en) | 2006-01-27 |
| ZA200404394B (en) | 2005-09-05 |
| DE60203937T2 (de) | 2006-05-11 |
| KR20050044329A (ko) | 2005-05-12 |
| CN1602306A (zh) | 2005-03-30 |
| EP1456193B1 (de) | 2005-04-27 |
| HRP20040490A2 (en) | 2004-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1456193 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |