DE60218048D1 - Thiophenverbindungen als arzneimittel - Google Patents
Thiophenverbindungen als arzneimittelInfo
- Publication number
- DE60218048D1 DE60218048D1 DE60218048T DE60218048T DE60218048D1 DE 60218048 D1 DE60218048 D1 DE 60218048D1 DE 60218048 T DE60218048 T DE 60218048T DE 60218048 T DE60218048 T DE 60218048T DE 60218048 D1 DE60218048 D1 DE 60218048D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- medicament
- thiophen
- compounds
- thiophen compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0102617 | 2001-07-25 | ||
SE0102617A SE0102617D0 (sv) | 2001-07-25 | 2001-07-25 | Novel compounds |
PCT/SE2002/001402 WO2003010163A1 (en) | 2001-07-25 | 2002-07-19 | Novel compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60218048D1 true DE60218048D1 (de) | 2007-03-22 |
DE60218048T2 DE60218048T2 (de) | 2007-08-09 |
Family
ID=20284945
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60218048T Expired - Lifetime DE60218048T2 (de) | 2001-07-25 | 2002-07-19 | Thiophenverbindungen als arzneimittel |
Country Status (17)
Country | Link |
---|---|
US (1) | US7098240B2 (de) |
EP (1) | EP1421079B1 (de) |
JP (2) | JP2004536869A (de) |
KR (1) | KR20040018521A (de) |
CN (1) | CN1538968A (de) |
AT (1) | ATE353327T1 (de) |
BR (1) | BR0211472A (de) |
CA (1) | CA2454702A1 (de) |
DE (1) | DE60218048T2 (de) |
ES (1) | ES2280559T3 (de) |
IL (1) | IL160023A0 (de) |
MX (1) | MXPA04000755A (de) |
NO (1) | NO20040314L (de) |
NZ (1) | NZ530751A (de) |
SE (1) | SE0102617D0 (de) |
WO (1) | WO2003010163A1 (de) |
ZA (1) | ZA200400494B (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0003154D0 (en) * | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
EP1401825B1 (de) * | 2001-06-11 | 2009-08-05 | Virochem Pharma Inc. | Thiophenderivate als antivirale mittel gegen flavivirus-infektion |
SE0102616D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
ES2315430T3 (es) * | 2001-10-04 | 2009-04-01 | Smithkline Beecham Corporation | Inhibidores de nf-kb. |
JP2005531608A (ja) * | 2002-06-06 | 2005-10-20 | スミスクライン・ビーチャム・コーポレイション | NF−κB阻害剤 |
KR101058696B1 (ko) | 2002-12-10 | 2011-08-22 | 바이로켐 파마 인코포레이티드 | 후라비바이러스 감염의 치료 또는 예방을 위한 화합물과방법 |
SE0300091D0 (sv) * | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
SE0300092D0 (sv) | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
US20050113566A1 (en) * | 2003-04-25 | 2005-05-26 | Player Mark R. | Inhibitors of C-FMS kinase |
US7790724B2 (en) | 2003-04-25 | 2010-09-07 | Janssen Pharmaceutica N.V. | c-fms kinase inhibitors |
WO2004096795A2 (en) * | 2003-04-25 | 2004-11-11 | 3-Dimensional Pharmaceuticals, Inc. | C-fms kinase inhibitors |
US7427683B2 (en) * | 2003-04-25 | 2008-09-23 | Ortho-Mcneil Pharmaceutical, Inc. | c-fms kinase inhibitors |
EP1493739A1 (de) * | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Thiophenderivate von Aminosäuren, Verfahren zu ihrer Herstellung und diese enthaltende Zusammensetzungen |
US20050085531A1 (en) * | 2003-10-03 | 2005-04-21 | Hodge Carl N. | Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof |
WO2005066163A2 (en) * | 2004-01-05 | 2005-07-21 | Astrazeneca Ab | Thiophene derivatives as chk 1 inihibitors |
PE20060373A1 (es) | 2004-06-24 | 2006-04-29 | Smithkline Beecham Corp | Derivados 3-piperidinil-7-carboxamida-indazol como inhibidores de la actividad cinasa de ikk2 |
PE20060748A1 (es) | 2004-09-21 | 2006-10-01 | Smithkline Beecham Corp | Derivados de indolcarboxamida como inhibidores de quinasa ikk2 |
ES2415742T3 (es) * | 2005-05-13 | 2013-07-26 | Vertex Pharmaceuticals (Canada) Incorporated | Compuestos y procedimientos para el tratamiento o prevención de infecciones por flavivirus |
US8063071B2 (en) | 2007-10-31 | 2011-11-22 | GlaxoSmithKline, LLC | Chemical compounds |
MX2007016541A (es) | 2005-06-30 | 2008-03-07 | Smithkline Beecham Corp | Compuestos quimicos. |
SG176488A1 (en) | 2006-11-15 | 2011-12-29 | Virochem Pharma Inc | Thiophene analogues for the treatment or prevention of flavivirus infections |
EP2119703B1 (de) * | 2007-01-15 | 2012-12-12 | Santen Pharmaceutical Co., Ltd | Neues indolderivat mit hemmender wirkung auf i-b-kinase |
PE20081889A1 (es) | 2007-03-23 | 2009-03-05 | Smithkline Beecham Corp | Indol carboxamidas como inhibidores de ikk2 |
US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
CN102014957B (zh) | 2008-04-21 | 2014-12-10 | 奥德纳米有限公司 | 用于治疗耳部疾病和病况的耳用调配物 |
WO2010007972A1 (ja) * | 2008-07-14 | 2010-01-21 | 参天製薬株式会社 | カルバモイル基、ウレイド基及び置換オキシ基を有する新規インドール誘導体 |
JP5492496B2 (ja) * | 2008-08-25 | 2014-05-14 | 参天製薬株式会社 | ウレイド基、アミノカルボニル基及び置換基を有してもよい二環式基を置換基として有する新規ピロール誘導体 |
WO2010102968A1 (en) | 2009-03-10 | 2010-09-16 | Glaxo Group Limited | Indole derivatives as ikk2 inhibitors |
GB0913345D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | New combination 802 |
WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
GB201016912D0 (en) | 2010-10-07 | 2010-11-24 | Astrazeneca Ab | Novel combination |
GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
EP2520292A1 (de) | 2011-05-06 | 2012-11-07 | Helmholtz-Zentrum für Infektionsforschung GmbH | Verwendung von Spirangienen zur Behandlung oder Prävention von IL-8- oder IL-6-vermittelten Erkrankungen |
EP3478269A4 (de) | 2016-06-29 | 2020-04-08 | Otonomy, Inc. | Triclyceridformulierungen für das ohr und verwendungen davon |
CN107739370B (zh) * | 2017-10-26 | 2021-03-30 | 中国药科大学 | 吡咯酮类brd4蛋白抑制剂的制备方法以及用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1468012A (en) | 1973-08-09 | 1977-03-23 | Beecham Group Ltd | 2-amino-3-carboxy-thiophene derivatives |
DE3529247A1 (de) | 1985-05-17 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung |
EP0912548A1 (de) | 1996-07-11 | 1999-05-06 | Pfizer Inc. | Pyridylpyrrol-derivate verwendbar als interleukin- und tnf- antagonisten |
PT853083E (pt) * | 1997-01-06 | 2001-12-28 | Pfizer | Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica |
US6809088B2 (en) * | 1997-03-24 | 2004-10-26 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them |
US6037340A (en) | 1997-05-28 | 2000-03-14 | Cadus Pharmaceutical Corporation | Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds |
DE19744026A1 (de) | 1997-10-06 | 1999-04-08 | Hoechst Marion Roussel De Gmbh | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
AU2713799A (en) | 1998-03-12 | 1999-09-27 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (ptpases) |
HN2000000051A (es) * | 1999-05-19 | 2001-02-02 | Pfizer Prod Inc | Derivados heterociclicos utiles como agentes anticancerosos |
IL151946A0 (en) * | 2000-03-29 | 2003-04-10 | Cyclacel Ltd | 2-substituted 4-heteroaryl-pyrimidines and their use in the treatment of proliferative disorders |
US6414013B1 (en) | 2000-06-19 | 2002-07-02 | Pharmacia & Upjohn S.P.A. | Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention |
JP2004523476A (ja) | 2000-10-12 | 2004-08-05 | スミスクライン・ビーチャム・コーポレイション | NF−κB阻害剤 |
-
2001
- 2001-07-25 SE SE0102617A patent/SE0102617D0/xx unknown
-
2002
- 2002-07-19 KR KR10-2004-7001155A patent/KR20040018521A/ko not_active Application Discontinuation
- 2002-07-19 EP EP02756047A patent/EP1421079B1/de not_active Expired - Lifetime
- 2002-07-19 AT AT02756047T patent/ATE353327T1/de not_active IP Right Cessation
- 2002-07-19 JP JP2003515522A patent/JP2004536869A/ja not_active Withdrawn
- 2002-07-19 CA CA002454702A patent/CA2454702A1/en not_active Abandoned
- 2002-07-19 MX MXPA04000755A patent/MXPA04000755A/es unknown
- 2002-07-19 ES ES02756047T patent/ES2280559T3/es not_active Expired - Lifetime
- 2002-07-19 US US10/484,645 patent/US7098240B2/en not_active Expired - Fee Related
- 2002-07-19 DE DE60218048T patent/DE60218048T2/de not_active Expired - Lifetime
- 2002-07-19 CN CNA028152514A patent/CN1538968A/zh active Pending
- 2002-07-19 WO PCT/SE2002/001402 patent/WO2003010163A1/en active IP Right Grant
- 2002-07-19 NZ NZ530751A patent/NZ530751A/en unknown
- 2002-07-19 BR BR0211472-0A patent/BR0211472A/pt not_active IP Right Cessation
- 2002-07-19 IL IL16002302A patent/IL160023A0/xx unknown
-
2004
- 2004-01-22 ZA ZA200400494A patent/ZA200400494B/en unknown
- 2004-01-23 NO NO20040314A patent/NO20040314L/no unknown
-
2009
- 2009-12-22 JP JP2009291103A patent/JP2010111683A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NZ530751A (en) | 2005-09-30 |
CA2454702A1 (en) | 2003-02-06 |
US7098240B2 (en) | 2006-08-29 |
JP2010111683A (ja) | 2010-05-20 |
EP1421079B1 (de) | 2007-02-07 |
IL160023A0 (en) | 2004-06-20 |
US20040235821A1 (en) | 2004-11-25 |
SE0102617D0 (sv) | 2001-07-25 |
BR0211472A (pt) | 2004-11-09 |
DE60218048T2 (de) | 2007-08-09 |
ZA200400494B (en) | 2005-04-22 |
KR20040018521A (ko) | 2004-03-03 |
WO2003010163A1 (en) | 2003-02-06 |
NO20040314L (no) | 2004-03-25 |
EP1421079A1 (de) | 2004-05-26 |
MXPA04000755A (es) | 2004-04-20 |
ATE353327T1 (de) | 2007-02-15 |
ES2280559T3 (es) | 2007-09-16 |
JP2004536869A (ja) | 2004-12-09 |
CN1538968A (zh) | 2004-10-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60218048D1 (de) | Thiophenverbindungen als arzneimittel | |
BR0211473A (pt) | Novos compostos | |
GB0003154D0 (en) | Novel compounds | |
HRP20040317A2 (en) | 1,8-naphthyridine derivatives as antidiabetics | |
SE0302760D0 (sv) | New compounds | |
SE0102439D0 (sv) | New compounds | |
SE0302116D0 (sv) | Novel compounds | |
NO20074657L (no) | Nitrogenholdige aromatiske ringforbindelser | |
BRPI0108395B8 (pt) | derivados de pirrolopirimidinona, processos de preparação e uso | |
UY27368A1 (es) | Nuevos compuestos | |
IS6520A (is) | Ný efnasambönd | |
HUP0401783A2 (hu) | 3,4-Diszubsztituált ciklobutén-1,2-dionok mint CXC-kemokin receptor ligandumok, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények | |
SE0300092D0 (sv) | Novel compounds | |
SE9802206D0 (sv) | Novel compounds | |
SE0300091D0 (sv) | Novel compounds | |
SE0102055D0 (sv) | New Compounds | |
SE0101322D0 (sv) | Novel compounds | |
SE0102440D0 (sv) | New compound | |
NO20055754L (no) | Kolkisosidanaloger | |
ATE228838T1 (de) | Neue n-acetylierte 4-hydroxyphenylaminen derivate mit analgetischen eigenschaften sowie diese enthaltende arzneimittel | |
ATE298564T1 (de) | Arzneimittelformulierung enthaltend einen ltb4 antagonisten und einen netzmittel | |
ATE342906T1 (de) | Tumorhemmende cerverbindungen | |
MY135855A (en) | "pyrrolopyrimidinone derivatives, process of preparation and use" | |
TH62250A (th) | ตัวยับยั้ง n-[5-[[[5-แอลคิล-2-ออกซาโซลิล]เมธิล]ไธออล]-2-ไธแอโซลิล]- คาร์บอกแซมีด ของไซคลินดีเพนเดนท์ไคเนส |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |