IL160023A0 - Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy - Google Patents
Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapyInfo
- Publication number
- IL160023A0 IL160023A0 IL16002302A IL16002302A IL160023A0 IL 160023 A0 IL160023 A0 IL 160023A0 IL 16002302 A IL16002302 A IL 16002302A IL 16002302 A IL16002302 A IL 16002302A IL 160023 A0 IL160023 A0 IL 160023A0
- Authority
- IL
- Israel
- Prior art keywords
- therapy
- preparation
- pharmaceutical compositions
- compositions containing
- thiopene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0102617A SE0102617D0 (sv) | 2001-07-25 | 2001-07-25 | Novel compounds |
PCT/SE2002/001402 WO2003010163A1 (en) | 2001-07-25 | 2002-07-19 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
IL160023A0 true IL160023A0 (en) | 2004-06-20 |
Family
ID=20284945
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16002302A IL160023A0 (en) | 2001-07-25 | 2002-07-19 | Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy |
Country Status (17)
Country | Link |
---|---|
US (1) | US7098240B2 (de) |
EP (1) | EP1421079B1 (de) |
JP (2) | JP2004536869A (de) |
KR (1) | KR20040018521A (de) |
CN (1) | CN1538968A (de) |
AT (1) | ATE353327T1 (de) |
BR (1) | BR0211472A (de) |
CA (1) | CA2454702A1 (de) |
DE (1) | DE60218048T2 (de) |
ES (1) | ES2280559T3 (de) |
IL (1) | IL160023A0 (de) |
MX (1) | MXPA04000755A (de) |
NO (1) | NO20040314L (de) |
NZ (1) | NZ530751A (de) |
SE (1) | SE0102617D0 (de) |
WO (1) | WO2003010163A1 (de) |
ZA (1) | ZA200400494B (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0003154D0 (en) * | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
AP1753A (en) * | 2001-06-11 | 2007-07-18 | Shire Biochem Inc | Thiophene derivatives as antiviral agents for flavvivirus infection |
SE0102616D0 (sv) | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
WO2003029242A1 (en) * | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | NF-λB INHIBITORS |
US7375131B2 (en) * | 2002-06-06 | 2008-05-20 | Smithklinebeecham Corp. | NF-κB inhibitors |
KR101058696B1 (ko) * | 2002-12-10 | 2011-08-22 | 바이로켐 파마 인코포레이티드 | 후라비바이러스 감염의 치료 또는 예방을 위한 화합물과방법 |
SE0300092D0 (sv) | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
SE0300091D0 (sv) * | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
US20050113566A1 (en) * | 2003-04-25 | 2005-05-26 | Player Mark R. | Inhibitors of C-FMS kinase |
JP2007525460A (ja) * | 2003-04-25 | 2007-09-06 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | c−fmsキナーゼ阻害剤 |
US7790724B2 (en) | 2003-04-25 | 2010-09-07 | Janssen Pharmaceutica N.V. | c-fms kinase inhibitors |
US7427683B2 (en) * | 2003-04-25 | 2008-09-23 | Ortho-Mcneil Pharmaceutical, Inc. | c-fms kinase inhibitors |
EP1493739A1 (de) * | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Thiophenderivate von Aminosäuren, Verfahren zu ihrer Herstellung und diese enthaltende Zusammensetzungen |
US20050085531A1 (en) * | 2003-10-03 | 2005-04-21 | Hodge Carl N. | Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof |
BRPI0418351A (pt) * | 2004-01-05 | 2007-05-08 | Astrazeneca Ab | composto ou um sal farmaceuticamente aceitável do mesmo, métodos de limitar a proliferação celular em um humano ou animal, de tratamento de um humano ou animal sofrendo de cáncer, de tratamento de profilaxia de cáncer, de tratamento de um humano ou animal sofrendo de uma doença neoplásica, de tratamento de um humano ou animal sofrendo de uma doença prolifetativa de tratamento de cáncer, para o tratamento de infecções associadas com cáncer, para o tratamento profilático de infecções associadas com cáncer, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, método de inibir a chk1 quinase, e, processo para a preparação de um composto ou um sal farmaceuticamente aceitável do mesmo |
AR050253A1 (es) | 2004-06-24 | 2006-10-11 | Smithkline Beecham Corp | Compuesto derivado de indazol carboxamida, composicion que lo comprende y su uso para la preparacion de un medicamento |
TW200626142A (en) | 2004-09-21 | 2006-08-01 | Glaxo Group Ltd | Chemical compounds |
ES2415742T3 (es) | 2005-05-13 | 2013-07-26 | Vertex Pharmaceuticals (Canada) Incorporated | Compuestos y procedimientos para el tratamiento o prevención de infecciones por flavivirus |
AU2006266028B2 (en) | 2005-06-30 | 2012-03-15 | Smithkline Beecham Corporation | Chemical compounds |
US8063071B2 (en) | 2007-10-31 | 2011-11-22 | GlaxoSmithKline, LLC | Chemical compounds |
EA201101492A1 (ru) * | 2006-11-15 | 2012-09-28 | Вирокем Фарма Инк. | Аналоги тиофена для лечения или предупреждения флавивирусных инфекций |
EP2119703B1 (de) * | 2007-01-15 | 2012-12-12 | Santen Pharmaceutical Co., Ltd | Neues indolderivat mit hemmender wirkung auf i-b-kinase |
AR065804A1 (es) | 2007-03-23 | 2009-07-01 | Smithkline Beecham Corp | Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento |
CN104491864A (zh) | 2008-04-21 | 2015-04-08 | 奥德纳米有限公司 | 用于治疗耳部疾病和病况的耳用调配物及方法 |
US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
US8445529B2 (en) * | 2008-07-14 | 2013-05-21 | Santen Pharmaceutical Co., Ltd. | Indole derivative having, carbamoyl group, ureido group and substituted oxy group |
KR20110044767A (ko) * | 2008-08-25 | 2011-04-29 | 산텐 세이야꾸 가부시키가이샤 | 우레이도기, 아미노카르보닐기 및 치환기를 가져도 좋은 2환식기를 치환기로서 갖는 신규 피롤 유도체 |
US8354539B2 (en) | 2009-03-10 | 2013-01-15 | Glaxo Group Limited | Indole derivatives as IKK2 inhibitors |
GB0913345D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | New combination 802 |
WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
GB201016912D0 (en) | 2010-10-07 | 2010-11-24 | Astrazeneca Ab | Novel combination |
GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
EP2520292A1 (de) | 2011-05-06 | 2012-11-07 | Helmholtz-Zentrum für Infektionsforschung GmbH | Verwendung von Spirangienen zur Behandlung oder Prävention von IL-8- oder IL-6-vermittelten Erkrankungen |
AU2017290256A1 (en) | 2016-06-29 | 2019-01-17 | Otonomy, Inc. | Triglyceride otic formulations and uses thereof |
CN107739370B (zh) * | 2017-10-26 | 2021-03-30 | 中国药科大学 | 吡咯酮类brd4蛋白抑制剂的制备方法以及用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1468012A (en) | 1973-08-09 | 1977-03-23 | Beecham Group Ltd | 2-amino-3-carboxy-thiophene derivatives |
DE3529247A1 (de) | 1985-05-17 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung |
WO1998002430A1 (en) | 1996-07-11 | 1998-01-22 | Pfizer Pharmaceuticals Inc. | Pyridylpyrrole compounds useful as interleukin- and tnf antagonists |
PT853083E (pt) * | 1997-01-06 | 2001-12-28 | Pfizer | Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica |
US6809088B2 (en) * | 1997-03-24 | 2004-10-26 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them |
US6037340A (en) | 1997-05-28 | 2000-03-14 | Cadus Pharmaceutical Corporation | Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds |
DE19744026A1 (de) | 1997-10-06 | 1999-04-08 | Hoechst Marion Roussel De Gmbh | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
WO1999046244A1 (en) | 1998-03-12 | 1999-09-16 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (ptpases) |
HN2000000051A (es) * | 1999-05-19 | 2001-02-02 | Pfizer Prod Inc | Derivados heterociclicos utiles como agentes anticancerosos |
CN100355751C (zh) * | 2000-03-29 | 2007-12-19 | 西克拉塞尔有限公司 | 2-取代的4-杂芳基-嘧啶、其组合物及其用途 |
US6414013B1 (en) | 2000-06-19 | 2002-07-02 | Pharmacia & Upjohn S.P.A. | Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention |
JP2004523476A (ja) | 2000-10-12 | 2004-08-05 | スミスクライン・ビーチャム・コーポレイション | NF−κB阻害剤 |
-
2001
- 2001-07-25 SE SE0102617A patent/SE0102617D0/xx unknown
-
2002
- 2002-07-19 IL IL16002302A patent/IL160023A0/xx unknown
- 2002-07-19 JP JP2003515522A patent/JP2004536869A/ja not_active Withdrawn
- 2002-07-19 ES ES02756047T patent/ES2280559T3/es not_active Expired - Lifetime
- 2002-07-19 CN CNA028152514A patent/CN1538968A/zh active Pending
- 2002-07-19 BR BR0211472-0A patent/BR0211472A/pt not_active IP Right Cessation
- 2002-07-19 EP EP02756047A patent/EP1421079B1/de not_active Expired - Lifetime
- 2002-07-19 CA CA002454702A patent/CA2454702A1/en not_active Abandoned
- 2002-07-19 DE DE60218048T patent/DE60218048T2/de not_active Expired - Lifetime
- 2002-07-19 MX MXPA04000755A patent/MXPA04000755A/es unknown
- 2002-07-19 US US10/484,645 patent/US7098240B2/en not_active Expired - Fee Related
- 2002-07-19 WO PCT/SE2002/001402 patent/WO2003010163A1/en active IP Right Grant
- 2002-07-19 NZ NZ530751A patent/NZ530751A/en unknown
- 2002-07-19 KR KR10-2004-7001155A patent/KR20040018521A/ko not_active Application Discontinuation
- 2002-07-19 AT AT02756047T patent/ATE353327T1/de not_active IP Right Cessation
-
2004
- 2004-01-22 ZA ZA200400494A patent/ZA200400494B/en unknown
- 2004-01-23 NO NO20040314A patent/NO20040314L/no unknown
-
2009
- 2009-12-22 JP JP2009291103A patent/JP2010111683A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE60218048D1 (de) | 2007-03-22 |
NZ530751A (en) | 2005-09-30 |
BR0211472A (pt) | 2004-11-09 |
CN1538968A (zh) | 2004-10-20 |
KR20040018521A (ko) | 2004-03-03 |
WO2003010163A1 (en) | 2003-02-06 |
JP2004536869A (ja) | 2004-12-09 |
US20040235821A1 (en) | 2004-11-25 |
CA2454702A1 (en) | 2003-02-06 |
ES2280559T3 (es) | 2007-09-16 |
DE60218048T2 (de) | 2007-08-09 |
SE0102617D0 (sv) | 2001-07-25 |
ATE353327T1 (de) | 2007-02-15 |
EP1421079B1 (de) | 2007-02-07 |
NO20040314L (no) | 2004-03-25 |
JP2010111683A (ja) | 2010-05-20 |
MXPA04000755A (es) | 2004-04-20 |
US7098240B2 (en) | 2006-08-29 |
ZA200400494B (en) | 2005-04-22 |
EP1421079A1 (de) | 2004-05-26 |
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