HUP0402152A3 - Preparation of trans-fused 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives - Google Patents

Preparation of trans-fused 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives

Info

Publication number
HUP0402152A3
HUP0402152A3 HU0402152A HUP0402152A HUP0402152A3 HU P0402152 A3 HUP0402152 A3 HU P0402152A3 HU 0402152 A HU0402152 A HU 0402152A HU P0402152 A HUP0402152 A HU P0402152A HU P0402152 A3 HUP0402152 A3 HU P0402152A3
Authority
HU
Hungary
Prior art keywords
cyclohepta
dibenzo
tetrahydro
trans
fused
Prior art date
Application number
HU0402152A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HUP0402152A2 publication Critical patent/HUP0402152A2/hu
Publication of HUP0402152A3 publication Critical patent/HUP0402152A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
HU0402152A 2001-12-07 2002-12-02 Preparation of trans-fused 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives HUP0402152A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01204961 2001-12-07
PCT/EP2002/013560 WO2003048146A1 (en) 2001-12-07 2002-12-02 PREPARATION OF TRANS-FUSED 3,3a,8,12b-TETRAHYDRO-2H-DIBENZO[3,4:6,7]CYCLOHEPTA[1,2-b]FURAN DERIVATIVES

Publications (2)

Publication Number Publication Date
HUP0402152A2 HUP0402152A2 (hu) 2005-02-28
HUP0402152A3 true HUP0402152A3 (en) 2007-03-28

Family

ID=8181460

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0402152A HUP0402152A3 (en) 2001-12-07 2002-12-02 Preparation of trans-fused 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives

Country Status (21)

Country Link
US (2) US6998494B2 (hu)
EP (1) EP1456193B1 (hu)
JP (1) JP4516752B2 (hu)
KR (1) KR20050044329A (hu)
CN (1) CN1293066C (hu)
AT (1) ATE294168T1 (hu)
AU (1) AU2002342926B2 (hu)
BR (1) BR0214068A (hu)
CA (1) CA2468038C (hu)
DE (1) DE60203937T2 (hu)
ES (1) ES2242076T3 (hu)
HK (1) HK1076461A1 (hu)
HR (1) HRP20040490A2 (hu)
HU (1) HUP0402152A3 (hu)
IL (1) IL162349A0 (hu)
MX (1) MXPA04005400A (hu)
NO (1) NO20042884L (hu)
NZ (1) NZ532806A (hu)
PL (1) PL369585A1 (hu)
WO (1) WO2003048146A1 (hu)
ZA (1) ZA200404394B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4516752B2 (ja) * 2001-12-07 2010-08-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ トランス−縮合3,3a,8,12b−テトラヒドロ−2H−ジベンゾ[3,4:6,7]シクロヘプタ[1,2−b]フラン誘導体の製造法
WO2005013969A1 (en) * 2003-07-15 2005-02-17 Janssen Pharmaceutica N.V. Antipsychotic agent with socializing properties
US20070197525A1 (en) * 2004-06-14 2007-08-23 Cid-Nunez Jose M Novel tetracyclic tetrahydrofuran derivatives
US7470809B2 (en) 2004-08-31 2008-12-30 Janssen Pharmaceutica N.V. Process for the production of [2-(4-fluoro-benzyl)-phenyl]-acetic acid
RU2401257C2 (ru) 2004-12-07 2010-10-10 Янссен Фармацевтика Н.В. Новые замещенные тетрациклические производные тетрагидрофурана, пирролидина и тетрагидротиофена
WO2006079637A1 (en) 2005-01-27 2006-08-03 Janssen Pharmaceutica N.V. Heterocyclic tetracyclic tetrahydrofuran derivatives as 5ht2 inhibitors in the treatment of cns disorders
MX2007016247A (es) 2005-06-17 2008-03-10 Janssen Pharmaceutica Nv Derivados de tetrahidrofurano tetraciclicos novedosos que contienen una cadena lateral de amida ciclica.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3199751B2 (ja) * 1996-04-12 2001-08-20 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 置換された四環式テトラヒドロフラン誘導体
UA52778C2 (uk) * 1997-10-10 2003-01-15 Янссен Фармацевтика Н.В. Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі
UA79248C2 (en) * 2001-11-09 2007-06-11 Janssen Pharmaceutica Nv Mandelate salts of substituted tetracyclic tetrahydrofuran derivatives
JP4516752B2 (ja) * 2001-12-07 2010-08-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ トランス−縮合3,3a,8,12b−テトラヒドロ−2H−ジベンゾ[3,4:6,7]シクロヘプタ[1,2−b]フラン誘導体の製造法
PL370440A1 (en) * 2001-12-07 2005-05-30 Janssen Pharmaceutica N.V. Preparation of cis-fused 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives

Also Published As

Publication number Publication date
JP2005511691A (ja) 2005-04-28
US20050014820A1 (en) 2005-01-20
PL369585A1 (en) 2005-05-02
US20050228043A1 (en) 2005-10-13
DE60203937D1 (de) 2005-06-02
HRP20040490A2 (en) 2004-10-31
MXPA04005400A (es) 2004-10-11
BR0214068A (pt) 2004-10-13
CN1293066C (zh) 2007-01-03
HUP0402152A2 (hu) 2005-02-28
JP4516752B2 (ja) 2010-08-04
ATE294168T1 (de) 2005-05-15
AU2002342926A1 (en) 2003-06-17
ES2242076T3 (es) 2005-11-01
CA2468038A1 (en) 2003-06-12
DE60203937T2 (de) 2006-05-11
US6998494B2 (en) 2006-02-14
HK1076461A1 (en) 2006-01-20
NO20042884L (no) 2004-07-07
WO2003048146A1 (en) 2003-06-12
KR20050044329A (ko) 2005-05-12
CA2468038C (en) 2011-04-26
CN1602306A (zh) 2005-03-30
ZA200404394B (en) 2005-09-05
IL162349A0 (en) 2005-11-20
EP1456193A1 (en) 2004-09-15
AU2002342926B2 (en) 2009-02-26
EP1456193B1 (en) 2005-04-27
NZ532806A (en) 2006-01-27

Similar Documents

Publication Publication Date Title
IL144008A0 (en) Production of isoflavone derivatives
HK1208446A1 (en) Derivatives of uk-2a uk-2a
HUP1100350A2 (en) Maleate addition salts of hydropyridine derivates
SI1401825T1 (sl) Tiofenski derivati kot protivirusna sredstva za flavirusno infekcijo
IL160166A0 (en) Method for the preparation of hexahydro-furo[2,3-b] furan-3-ol
HK1068069A1 (en) Method for the preparation of intermediate of citalopram
IL155966A0 (en) Benzothiophene derivative compounds, process of preparation and use thereof
IL157889A0 (en) Substituted benzofuran-2-carboxamide derivatives
HUP0402152A3 (en) Preparation of trans-fused 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives
PL370440A1 (en) Preparation of cis-fused 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives
HUP0302534A3 (en) Preparation of mandelic acid derivatives
AU2002303529A1 (en) Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
IL149534A0 (en) Preparation of 3-substituted-4-arylquinolin-2-one derivatives
IL152893A0 (en) Novel benzofuran derivatives
PL338628A1 (en) Method of obtaining derivatives of 2,3,3a,4,6,7-hexahydropyrasole [4,3-c] pyridine, method of obtaining l-tartrate of such derivative and novel polymorph of dihydrate of so obtained l-tartrate
IL152894A0 (en) Novel benzothiophene derivatives
HUP0202485A3 (en) Novel benzo[b]pyrano[3,2-h]acridin-7-one derivatives, process for their preparation and pharmaceutical compositions containing them
AU2003231925A8 (en) (e)-oxime ether derivative of 5,6-dihydro-benzo(5,6)cyclohepta(1,2-b)pyridin-11-one
MXPA03004295A (es) Produccion de 6-aminocaproato de alquilo.
PL346352A1 (en) Novel derivatives of 8-chloro-5,5-dioxoimidazo [1,2-b] [1,4,2]-benzothiazine, intermediate compound and methods of obtaining them
PL347407A1 (en) Method of obtaining derivatives of 5,6,7,8-tetrahydronaphtalen-2-ole
AU2002307501A1 (en) Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino(2,3-b)pyridine
GB0122421D0 (en) Preparation of artemisinin derivatives
IL158928A0 (en) (PYRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES
SI1301469T1 (sl) Priprava 4-tioalkilbromobenzenskih derivatov