ATE263185T1 - Verfahren zur herstellung von acylierten proteinpuder - Google Patents

Verfahren zur herstellung von acylierten proteinpuder

Info

Publication number
ATE263185T1
ATE263185T1 AT96303974T AT96303974T ATE263185T1 AT E263185 T1 ATE263185 T1 AT E263185T1 AT 96303974 T AT96303974 T AT 96303974T AT 96303974 T AT96303974 T AT 96303974T AT E263185 T1 ATE263185 T1 AT E263185T1
Authority
AT
Austria
Prior art keywords
protein
protein powder
acylated protein
producing acylated
isoelectric
Prior art date
Application number
AT96303974T
Other languages
German (de)
English (en)
Inventor
Jeffrey Clayton Baker
Brian A Moser
Warren E Schrader
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE263185T1 publication Critical patent/ATE263185T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96303974T 1995-06-07 1996-05-31 Verfahren zur herstellung von acylierten proteinpuder ATE263185T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/484,220 US5700904A (en) 1995-06-07 1995-06-07 Preparation of an acylated protein powder

Publications (1)

Publication Number Publication Date
ATE263185T1 true ATE263185T1 (de) 2004-04-15

Family

ID=23923252

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96303974T ATE263185T1 (de) 1995-06-07 1996-05-31 Verfahren zur herstellung von acylierten proteinpuder

Country Status (21)

Country Link
US (1) US5700904A (enExample)
EP (1) EP0747391B1 (enExample)
JP (1) JP3844504B2 (enExample)
KR (1) KR19990022590A (enExample)
CN (1) CN1192218A (enExample)
AT (1) ATE263185T1 (enExample)
AU (1) AU703032B2 (enExample)
BR (1) BR9608729A (enExample)
CA (1) CA2223389A1 (enExample)
CZ (1) CZ388197A3 (enExample)
DE (1) DE69631996T2 (enExample)
DK (1) DK0747391T3 (enExample)
EA (1) EA199800042A1 (enExample)
ES (1) ES2216039T3 (enExample)
HU (1) HUP9900877A3 (enExample)
IL (1) IL122460A0 (enExample)
NO (1) NO975583D0 (enExample)
NZ (1) NZ309371A (enExample)
PL (1) PL323994A1 (enExample)
TR (1) TR199701528T1 (enExample)
WO (1) WO1996040730A1 (enExample)

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US6799682B1 (en) 2000-05-16 2004-10-05 Roe-Hoan Yoon Method of increasing flotation rate
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US6867183B2 (en) 2001-02-15 2005-03-15 Nobex Corporation Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7060675B2 (en) 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
US6828297B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828305B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
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US6835802B2 (en) * 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US6858580B2 (en) * 2001-06-04 2005-02-22 Nobex Corporation Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
US6913903B2 (en) 2001-09-07 2005-07-05 Nobex Corporation Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
US7166571B2 (en) 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
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US7196059B2 (en) 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7312192B2 (en) 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
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JP4022595B2 (ja) * 2004-10-26 2007-12-19 コニカミノルタオプト株式会社 撮影装置
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US7741281B2 (en) * 2005-11-03 2010-06-22 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
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HRP20151325T1 (hr) 2009-01-23 2016-01-01 Rigel Pharmaceuticals, Inc. Pripravci i postupci za inhibiciju jak puta
CN102770152B (zh) 2009-11-25 2016-07-06 阿瑞斯根股份有限公司 肽类的粘膜递送
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US11206846B2 (en) * 2017-05-02 2021-12-28 Leprino Foods Company High purity alpha lactalbumin and methods of making
WO2019064125A1 (en) 2017-09-26 2019-04-04 Biocon Limited INTEGRATED AUTOMATED FILTRATION FOR THE SEPARATION, WASHING AND DRYING OF PEPTIDE CRYSTALS
US20220000880A1 (en) 2018-11-01 2022-01-06 Rigel Pharmaceuticals, Inc. Method and composition embodiments for treating acute myeloid leukemia
US20200377518A1 (en) 2019-05-29 2020-12-03 Rigel Pharmaceuticals, Inc. Method of preventing and treating thrombosis
CA3147443A1 (en) 2019-08-08 2021-02-11 Rigel Pharmaceuticals, Inc. Compounds and method for treating cytokine release syndrome
ES2970382T3 (es) 2019-08-14 2024-05-28 Rigel Pharmaceuticals Inc Método para bloquear o mejorar el síndrome de liberación de citocinas
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Also Published As

Publication number Publication date
IL122460A0 (en) 1998-06-15
EA199800042A1 (ru) 1998-08-27
DE69631996D1 (de) 2004-05-06
CA2223389A1 (en) 1996-12-19
KR19990022590A (ko) 1999-03-25
HUP9900877A3 (en) 1999-11-29
DE69631996T2 (de) 2005-01-27
HUP9900877A2 (hu) 1999-07-28
WO1996040730A1 (en) 1996-12-19
US5700904A (en) 1997-12-23
AU5951396A (en) 1996-12-30
ES2216039T3 (es) 2004-10-16
AU703032B2 (en) 1999-03-11
TR199701528T1 (xx) 1998-03-21
JP3844504B2 (ja) 2006-11-15
NO975583L (no) 1997-12-03
EP0747391B1 (en) 2004-03-31
EP0747391A2 (en) 1996-12-11
MX9709657A (es) 1998-07-31
PL323994A1 (en) 1998-04-27
DK0747391T3 (da) 2004-07-19
JPH11506738A (ja) 1999-06-15
NO975583D0 (no) 1997-12-03
BR9608729A (pt) 1999-06-29
NZ309371A (en) 1999-09-29
CZ388197A3 (cs) 1998-05-13
CN1192218A (zh) 1998-09-02
EP0747391A3 (en) 1997-05-21

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