DE60125218D1 - Verfahren zur herstellung von humanem serumalbumin unter verwendung eines aufwarmschrittes - Google Patents

Verfahren zur herstellung von humanem serumalbumin unter verwendung eines aufwarmschrittes

Info

Publication number
DE60125218D1
DE60125218D1 DE60125218T DE60125218T DE60125218D1 DE 60125218 D1 DE60125218 D1 DE 60125218D1 DE 60125218 T DE60125218 T DE 60125218T DE 60125218 T DE60125218 T DE 60125218T DE 60125218 D1 DE60125218 D1 DE 60125218D1
Authority
DE
Germany
Prior art keywords
serum albumin
human serum
heating step
producing human
contaminants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60125218T
Other languages
English (en)
Other versions
DE60125218T2 (de
Inventor
T Nouchi
H Mizokami
Y Tajima
Y Miyatsu
M Sakaguchi
K Yagi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Application granted granted Critical
Publication of DE60125218D1 publication Critical patent/DE60125218D1/de
Publication of DE60125218T2 publication Critical patent/DE60125218T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DE60125218T 2000-10-24 2001-10-24 Verfahren zur herstellung von humanen serumalbumin unter einbeziehen eines erwärmungsschrittes Expired - Lifetime DE60125218T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000324030 2000-10-24
JP2000324030A JP4798833B2 (ja) 2000-10-24 2000-10-24 加熱処理工程を含むヒト血清アルブミンの製造方法
PCT/JP2001/009336 WO2002034787A1 (fr) 2000-10-24 2001-10-24 Procede d"elaboration d"albumine de serum d"origine humaine comportant une etape de chauffage

Publications (2)

Publication Number Publication Date
DE60125218D1 true DE60125218D1 (de) 2007-01-25
DE60125218T2 DE60125218T2 (de) 2007-09-20

Family

ID=18801621

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60125218T Expired - Lifetime DE60125218T2 (de) 2000-10-24 2001-10-24 Verfahren zur herstellung von humanen serumalbumin unter einbeziehen eines erwärmungsschrittes

Country Status (12)

Country Link
US (1) US6908749B2 (de)
EP (1) EP1329462B1 (de)
JP (1) JP4798833B2 (de)
KR (1) KR100839937B1 (de)
CN (1) CN1313493C (de)
AT (1) ATE348111T1 (de)
AU (1) AU783638B2 (de)
CA (1) CA2395590C (de)
DE (1) DE60125218T2 (de)
DK (1) DK1329462T3 (de)
ES (1) ES2272548T3 (de)
WO (1) WO2002034787A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002034785A1 (fr) * 2000-10-24 2002-05-02 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Procede de monomerisation de polymeres d"albumine serique humaine
ATE382057T1 (de) 2001-06-28 2008-01-15 Novo Nordisk As Stabile formulierung von modifiziertem glp-1
AU2003281982A1 (en) * 2002-11-26 2004-06-18 Novo Nordisk A/S Process for purifying a fermentation-derived product
GB0305989D0 (en) * 2003-03-15 2003-04-23 Delta Biotechnology Ltd Agent
PL1633391T3 (pl) 2003-06-03 2012-03-30 Novo Nordisk As Stabilizowane farmaceutycznie kompozycje peptydowe
JP4936884B2 (ja) 2003-06-03 2012-05-23 ノボ・ノルデイスク・エー/エス 安定化された薬学的ペプチド組成物
HUE038395T2 (hu) 2003-11-20 2018-10-29 Novo Nordisk As Propilén-glikol tartalmú peptidkészítmények, amelyek elõállításra és injekciós eszközökben történõ alkalmazásra optimálisak
DK1710250T3 (da) * 2004-01-20 2009-07-06 Chemo Sero Therapeut Res Inst Fremgangsmåde til fremstilling af humanserumalbumin ved varnebehandling i tilstedeværelse af divalt kation
JP4965446B2 (ja) 2004-08-31 2012-07-04 ノヴォ ノルディスク アー/エス ペプチド、ポリペプチド及びタンパク質の安定化のためのトリス(ヒドロキシメチル)アミノメタンの使用
AU2005303777B2 (en) 2004-11-12 2010-12-16 Novo Nordisk A/S Stable formulations of insulinotropic peptides
US20100168000A1 (en) 2005-12-22 2010-07-01 Peter Kiessling Octanoate-Reduced Human Albumin
JP4936272B2 (ja) * 2006-02-13 2012-05-23 独立行政法人科学技術振興機構 バイオナノカプセルの効率的な精製法
EP2170356A1 (de) * 2007-06-25 2010-04-07 Fred Hutchinson Cancer Research Center Polychalcogenid-zusammensetzungen betreffende verfahren und zusammensetzungen
ES2761854T3 (es) 2016-10-04 2020-05-21 Albumedix Ltd Usos de albúmina de suero recombinante obtenida a partir de levadura
CN106749623B (zh) * 2016-12-09 2020-04-10 浙江大学 一种基于混合模式的扩张床吸附分离人血白蛋白方法
TWI762706B (zh) 2017-08-24 2022-05-01 丹麥商諾佛 儂迪克股份有限公司 Glp-1組成物及其用途
EP4069200A1 (de) 2019-12-04 2022-10-12 Albumedix Ltd Verfahren und damit hergestellte zusammensetzungen
BR112022013795A2 (pt) 2020-02-18 2022-09-13 Novo Nordisk As Composição farmacêutica líquida, e, kit
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5071897A (de) * 1973-11-07 1975-06-14
US4025500A (en) * 1974-06-06 1977-05-24 Baxter Laboratories, Inc. Preparation of albumin by fractionation of blood plasma or serum
IL66614A (en) 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
US5004688A (en) * 1988-04-15 1991-04-02 Phillips Petroleum Company Purification of hepatitis proteins
JP2926722B2 (ja) 1988-10-20 1999-07-28 吉富製薬株式会社 アルブミン製剤及びその製造方法
JPH0768137B2 (ja) * 1989-06-15 1995-07-26 株式会社ミドリ十字 アルブミン製剤及びその製法
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
JPH04234326A (ja) * 1990-12-27 1992-08-24 Green Cross Corp:The アルブミン製剤及びその製法
JPH0671434A (ja) 1991-05-30 1994-03-15 Tadahiro Omi クリーンチャンバーの溶接方法
US5440018A (en) 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
JP3269504B2 (ja) * 1992-07-08 2002-03-25 三菱ウェルファーマ株式会社 ヒト血清アルブミンの製造方法
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
JPH07126182A (ja) * 1993-10-27 1995-05-16 Green Cross Corp:The 組換えヒト血清アルブミン製剤の滅菌方法
JP3840674B2 (ja) * 1994-08-31 2006-11-01 三菱ウェルファーマ株式会社 遺伝子操作に由来するヒト血清アルブミンの精製方法
JP4158863B2 (ja) * 1996-08-23 2008-10-01 キリンホールディングス株式会社 酵母ベクターおよびそれを用いたタンパク質の製造法
JP2885212B2 (ja) * 1997-01-06 1999-04-19 吉富製薬株式会社 遺伝子操作由来のヒト血清アルブミンより得られる高純度ヒト血清アルブミン含有組成物

Also Published As

Publication number Publication date
AU783638B2 (en) 2005-11-17
US6908749B2 (en) 2005-06-21
EP1329462A1 (de) 2003-07-23
AU1093602A (en) 2002-05-06
DE60125218T2 (de) 2007-09-20
JP4798833B2 (ja) 2011-10-19
CA2395590C (en) 2012-12-11
KR100839937B1 (ko) 2008-06-20
CN1406246A (zh) 2003-03-26
WO2002034787A1 (fr) 2002-05-02
JP2002128796A (ja) 2002-05-09
EP1329462B1 (de) 2006-12-13
EP1329462A4 (de) 2004-09-08
ES2272548T3 (es) 2007-05-01
DK1329462T3 (da) 2007-01-22
CA2395590A1 (en) 2002-05-02
KR20020065609A (ko) 2002-08-13
ATE348111T1 (de) 2007-01-15
CN1313493C (zh) 2007-05-02
US20020182680A1 (en) 2002-12-05

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