DE60009807D1 - Verfahren zur herstellung von (-)pyridobenzoxazin-carbonsäure-derivaten - Google Patents

Verfahren zur herstellung von (-)pyridobenzoxazin-carbonsäure-derivaten

Info

Publication number
DE60009807D1
DE60009807D1 DE60009807T DE60009807T DE60009807D1 DE 60009807 D1 DE60009807 D1 DE 60009807D1 DE 60009807 T DE60009807 T DE 60009807T DE 60009807 T DE60009807 T DE 60009807T DE 60009807 D1 DE60009807 D1 DE 60009807D1
Authority
DE
Germany
Prior art keywords
pyridobenzoxazine
producing
acid derivatives
carbonic acid
carbonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60009807T
Other languages
English (en)
Other versions
DE60009807T2 (de
Inventor
Young-Jun Park
Ho-Seong Lee
Min-Hwan Kim
Kyung-Chul Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Samsung Electronics Co Ltd
Original Assignee
Samsung Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samsung Electronics Co Ltd filed Critical Samsung Electronics Co Ltd
Application granted granted Critical
Publication of DE60009807D1 publication Critical patent/DE60009807D1/de
Publication of DE60009807T2 publication Critical patent/DE60009807T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE60009807T 1999-02-24 2000-02-23 Verfahren zur herstellung von (-)pyridobenzoxazin-carbonsäure-derivaten Expired - Lifetime DE60009807T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1019990006093A KR100309871B1 (ko) 1999-02-24 1999-02-24 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
KR9906093 1999-02-24
PCT/KR2000/000145 WO2000050428A1 (en) 1999-02-24 2000-02-23 Process for preparing (-)pyridobenzoxazine carboxylic acid derivatives

Publications (2)

Publication Number Publication Date
DE60009807D1 true DE60009807D1 (de) 2004-05-19
DE60009807T2 DE60009807T2 (de) 2005-04-28

Family

ID=19574927

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60009807T Expired - Lifetime DE60009807T2 (de) 1999-02-24 2000-02-23 Verfahren zur herstellung von (-)pyridobenzoxazin-carbonsäure-derivaten

Country Status (9)

Country Link
US (1) US6316618B1 (de)
EP (1) EP1073662B1 (de)
JP (1) JP3530784B2 (de)
KR (1) KR100309871B1 (de)
CN (1) CN1125073C (de)
BR (1) BR0005132B1 (de)
DE (1) DE60009807T2 (de)
ES (1) ES2215024T3 (de)
WO (1) WO2000050428A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100494882B1 (ko) * 1999-08-21 2005-06-14 경동제약 주식회사 (-)-9-플루오로-2,3-디히드로-3(ｓ)-메틸-10-(4-메틸-1-피페라지닐)-7-옥소-7ｈ-피리도[1,2,3-데]-1,4-벤즈옥사진-6-카르복실산의 제조방법
SE0000933D0 (sv) 2000-03-21 2000-03-21 Independent Pharmaceutica Ab Method of producing 6-substituted (S)-nicotine derivatives and intermediate compounds
DE60215213T3 (de) * 2001-10-03 2010-07-01 Teva Pharmaceutical Industries Ltd. Herstellung von levofloxacin-hemihydrat
US7425628B2 (en) 2001-10-03 2008-09-16 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin
MXPA04005196A (es) * 2001-11-29 2005-11-23 Teva Pharma Metodos para la purificacion de levofloxacina.
KR100519158B1 (ko) 2002-12-21 2005-10-06 주식회사유한양행 퀴놀론 카르복실레이트 유도체의 제조방법
KR100542600B1 (ko) * 2004-05-17 2006-01-11 주식회사 카이로켐 광학활성 (s)-피리도벤즈옥사진 카르복실산 반수화물 유도체의 제조 방법
KR100704641B1 (ko) * 2004-07-21 2007-04-06 주식회사유한양행 고순도의 레보플록사신 제조방법
CN1332962C (zh) * 2005-07-12 2007-08-22 武汉人福药业有限责任公司 一种合成甲磺酸帕珠沙星中间体的方法
CN102827075A (zh) * 2011-06-14 2012-12-19 四川科伦药物研究有限公司 一种西他沙星中间体的合成方法
CN113717100B (zh) * 2021-10-11 2023-03-17 郑州工业应用技术学院 一种培氟沙星醛缩4-芳基氨基硫脲类衍生物的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US477273A (en) * 1892-06-21 Norman f
JPS5746986A (en) 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
DK170473B1 (da) 1985-06-20 1995-09-11 Daiichi Seiyaku Co S(-)-pyridobenzoxazinforbindelser
DE3522406A1 (de) 1985-06-22 1987-01-02 Bayer Ag Verfahren zur herstellung von 1,8-verbrueckten 4-chinolon-3-carbonsaeuren
US5237060A (en) 1985-12-10 1993-08-17 Bayer Aktiengesellschaft Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
US4777253A (en) 1986-04-25 1988-10-11 Abbott Laboratories Process for preparation of racemate and optically active ofloxacin and related derivatives
JPH0826029B2 (ja) 1987-12-22 1996-03-13 第一製薬株式会社 魚類感染症の予防・治療剤
JPH04504852A (ja) 1989-04-26 1992-08-27 ジ・アップジョン・カンパニー 抗菌性ピリド（１，２，３―デ）―１，４―ベンゾオキサジノン剤
KR0125115B1 (ko) * 1994-03-22 1997-12-05 김은영 (-)피페라진 벤즈옥사진 유도체의 제조방법
KR0142139B1 (ko) * 1994-03-22 1998-07-01 김은영 (+)2-벤조일-3-[(프로피-2(s)-일)아미노]아크릴레이트 유도체의 제조방법
GB2301354A (en) 1995-04-04 1996-12-04 Resolution Chemicals Limited Preparation for intermediates for quinolone antibiotics

Also Published As

Publication number Publication date
BR0005132A (pt) 2001-01-02
CN1294592A (zh) 2001-05-09
DE60009807T2 (de) 2005-04-28
EP1073662A1 (de) 2001-02-07
ES2215024T3 (es) 2004-10-01
KR20000056615A (ko) 2000-09-15
BR0005132B1 (pt) 2010-06-15
KR100309871B1 (ko) 2001-10-29
JP3530784B2 (ja) 2004-05-24
JP2000247980A (ja) 2000-09-12
EP1073662A4 (de) 2002-04-17
CN1125073C (zh) 2003-10-22
US6316618B1 (en) 2001-11-13
WO2000050428A1 (en) 2000-08-31
EP1073662B1 (de) 2004-04-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition