TR199701528T1 - Asillenmi� bir protein tozunun haz�rlanmas�. - Google Patents

Asillenmi� bir protein tozunun haz�rlanmas�.

Info

Publication number
TR199701528T1
TR199701528T1 TR97/01528T TR9701528T TR199701528T1 TR 199701528 T1 TR199701528 T1 TR 199701528T1 TR 97/01528 T TR97/01528 T TR 97/01528T TR 9701528 T TR9701528 T TR 9701528T TR 199701528 T1 TR199701528 T1 TR 199701528T1
Authority
TR
Turkey
Prior art keywords
protein
preparation
protein powder
aqueous protein
isoelectric
Prior art date
Application number
TR97/01528T
Other languages
English (en)
Turkish (tr)
Inventor
Clayton Baker Jeffrey
A. Moser Brian
E. Shrader Warren
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of TR199701528T1 publication Critical patent/TR199701528T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TR97/01528T 1995-06-07 1996-06-04 Asillenmi� bir protein tozunun haz�rlanmas�. TR199701528T1 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/484,220 US5700904A (en) 1995-06-07 1995-06-07 Preparation of an acylated protein powder

Publications (1)

Publication Number Publication Date
TR199701528T1 true TR199701528T1 (xx) 1998-03-21

Family

ID=23923252

Family Applications (1)

Application Number Title Priority Date Filing Date
TR97/01528T TR199701528T1 (xx) 1995-06-07 1996-06-04 Asillenmi� bir protein tozunun haz�rlanmas�.

Country Status (21)

Country Link
US (1) US5700904A (xx)
EP (1) EP0747391B1 (xx)
JP (1) JP3844504B2 (xx)
KR (1) KR19990022590A (xx)
CN (1) CN1192218A (xx)
AT (1) ATE263185T1 (xx)
AU (1) AU703032B2 (xx)
BR (1) BR9608729A (xx)
CA (1) CA2223389A1 (xx)
CZ (1) CZ388197A3 (xx)
DE (1) DE69631996T2 (xx)
DK (1) DK0747391T3 (xx)
EA (1) EA199800042A1 (xx)
ES (1) ES2216039T3 (xx)
HU (1) HUP9900877A3 (xx)
IL (1) IL122460A0 (xx)
NO (1) NO975583D0 (xx)
NZ (1) NZ309371A (xx)
PL (1) PL323994A1 (xx)
TR (1) TR199701528T1 (xx)
WO (1) WO1996040730A1 (xx)

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US5898028A (en) * 1997-03-20 1999-04-27 Novo Nordisk A/S Method for producing powder formulation comprising an insulin
AU1111799A (en) * 1997-10-24 1999-05-17 Eli Lilly And Company Fatty acid-acylated insulin analogs
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US6531448B1 (en) * 1997-12-23 2003-03-11 Eli Lilly And Company Insoluble compositions for controlling blood glucose
US6855260B1 (en) * 1999-06-07 2005-02-15 Roe-Hoan Yoon Methods of enhancing fine particle dewatering
US6526675B1 (en) * 1999-06-07 2003-03-04 Roe-Hoan Yoon Methods of using natural products as dewatering aids for fine particles
US7169889B1 (en) 1999-06-19 2007-01-30 Biocon Limited Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
US6799682B1 (en) 2000-05-16 2004-10-05 Roe-Hoan Yoon Method of increasing flotation rate
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
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US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
US6828305B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6713452B2 (en) 2001-06-04 2004-03-30 Nobex Corporation Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
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US6858580B2 (en) * 2001-06-04 2005-02-22 Nobex Corporation Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
US6913903B2 (en) 2001-09-07 2005-07-05 Nobex Corporation Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7166571B2 (en) 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7312192B2 (en) 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
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WO2006114396A1 (en) 2005-04-24 2006-11-02 Novo Nordisk A/S Injection device
US20070203161A1 (en) 2006-02-24 2007-08-30 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the jak pathway
CN105348203B (zh) 2005-06-08 2018-09-18 里格尔药品股份有限公司 抑制jak途径的组合物和方法
US7741281B2 (en) * 2005-11-03 2010-06-22 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
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US8343954B2 (en) 2010-07-28 2013-01-01 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the JAK pathway
US9533106B2 (en) 2011-12-29 2017-01-03 Novo Nordisk A/S Torsion-spring based wind-up auto injector pen with dial-up/dial-down mechanism
EP2828241B1 (en) 2012-03-23 2018-09-12 Mateon Therapeutics, Inc. Compositions and methods for inhibition of cathepsins
US11206846B2 (en) * 2017-05-02 2021-12-28 Leprino Foods Company High purity alpha lactalbumin and methods of making
CN111386281B (zh) 2017-09-26 2024-03-19 拜康生物制品印度有限公司 用于肽晶体的分离、洗涤和干燥的集成的自动化过滤
WO2020092845A1 (en) 2018-11-01 2020-05-07 Rigel Pharmaceuticals, Inc. Method and composition embodiments for treating acute myeloid leukemia
WO2020243612A1 (en) 2019-05-29 2020-12-03 Rigel Pharmaceuticals, Inc. Method of preventing and treating thrombosis
MX2022001596A (es) 2019-08-08 2022-03-11 Rigel Pharmaceuticals Inc Compuestos y metodos para tratar sindrome de liberacion de citocinas.
CN114286679A (zh) 2019-08-14 2022-04-05 里格尔药品股份有限公司 阻断或改善细胞因子释放综合征的方法
WO2023183377A1 (en) 2022-03-23 2023-09-28 Rigel Pharmaceuticals, Inc. Pyrimid-2-yl-pyrazole compounds as irak inhibitors

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Also Published As

Publication number Publication date
IL122460A0 (en) 1998-06-15
JP3844504B2 (ja) 2006-11-15
ATE263185T1 (de) 2004-04-15
CA2223389A1 (en) 1996-12-19
EP0747391A2 (en) 1996-12-11
NO975583L (no) 1997-12-03
CZ388197A3 (cs) 1998-05-13
DE69631996D1 (de) 2004-05-06
NZ309371A (en) 1999-09-29
WO1996040730A1 (en) 1996-12-19
EA199800042A1 (ru) 1998-08-27
DK0747391T3 (da) 2004-07-19
JPH11506738A (ja) 1999-06-15
CN1192218A (zh) 1998-09-02
MX9709657A (es) 1998-07-31
ES2216039T3 (es) 2004-10-16
KR19990022590A (ko) 1999-03-25
BR9608729A (pt) 1999-06-29
EP0747391B1 (en) 2004-03-31
HUP9900877A2 (hu) 1999-07-28
EP0747391A3 (en) 1997-05-21
DE69631996T2 (de) 2005-01-27
US5700904A (en) 1997-12-23
NO975583D0 (no) 1997-12-03
AU703032B2 (en) 1999-03-11
PL323994A1 (en) 1998-04-27
AU5951396A (en) 1996-12-30
HUP9900877A3 (en) 1999-11-29

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