BR9909636A - Processo para a preparação de uma formulação, e, formulação - Google Patents

Processo para a preparação de uma formulação, e, formulação

Info

Publication number
BR9909636A
BR9909636A BR9909636-6A BR9909636A BR9909636A BR 9909636 A BR9909636 A BR 9909636A BR 9909636 A BR9909636 A BR 9909636A BR 9909636 A BR9909636 A BR 9909636A
Authority
BR
Brazil
Prior art keywords
formulation
preparing
incorporation
precipitation
emulsion
Prior art date
Application number
BR9909636-6A
Other languages
English (en)
Inventor
Marie-Louise Andersson
Catherine Boissier
Anne Marie Juppo
Anette Larsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR9909636A publication Critical patent/BR9909636A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/105Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D11/00Solvent extraction
    • B01D11/04Solvent extraction of solutions which are liquid
    • B01D11/0403Solvent extraction of solutions which are liquid with a supercritical fluid
    • B01D11/0411Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984Microcapsule with fluid core [includes liposome]
    • Y10T428/2985Solid-walled microcapsule from synthetic polymer

Abstract

"PROCESSO PARA A PREPARAçãO DE UMA FORMULAçãO, E, FORMULAçãO" Um processo para a incorporação de uma substância ativa num sistema de veículo pela formação de uma emulsão de componentes e precipitação do sistema pelo uso de técnica de gás fluido.
BR9909636-6A 1998-04-14 1999-04-09 Processo para a preparação de uma formulação, e, formulação BR9909636A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801287A SE9801287D0 (sv) 1998-04-14 1998-04-14 Incorporation of active substances in carrier matrixes
PCT/SE1999/000583 WO1999052507A1 (en) 1998-04-14 1999-04-09 Incorporation of active substances in carrier matrixes

Publications (1)

Publication Number Publication Date
BR9909636A true BR9909636A (pt) 2000-12-19

Family

ID=20410946

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9909636-6A BR9909636A (pt) 1998-04-14 1999-04-09 Processo para a preparação de uma formulação, e, formulação

Country Status (31)

Country Link
US (1) US6372260B1 (pt)
EP (1) EP1069890B1 (pt)
JP (1) JP2002511400A (pt)
KR (1) KR100600691B1 (pt)
CN (1) CN1201728C (pt)
AR (1) AR019262A1 (pt)
AT (1) ATE329580T1 (pt)
AU (1) AU744874B2 (pt)
BR (1) BR9909636A (pt)
CA (1) CA2327522C (pt)
CY (1) CY1105154T1 (pt)
CZ (1) CZ20003784A3 (pt)
DE (1) DE69931904T2 (pt)
DK (1) DK1069890T3 (pt)
EE (1) EE200000595A (pt)
ES (1) ES2267268T3 (pt)
HU (1) HUP0102305A3 (pt)
ID (1) ID29286A (pt)
IL (1) IL138635A0 (pt)
IS (1) IS5656A (pt)
NO (1) NO329145B1 (pt)
NZ (1) NZ507190A (pt)
PL (1) PL344077A1 (pt)
PT (1) PT1069890E (pt)
RU (1) RU2208435C2 (pt)
SE (1) SE9801287D0 (pt)
SK (1) SK14112000A3 (pt)
TR (1) TR200002960T2 (pt)
TW (1) TW542724B (pt)
WO (1) WO1999052507A1 (pt)
ZA (1) ZA992549B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2729101A (en) * 1999-12-21 2001-07-03 Rxkinetix, Inc. Particulate drug-containing products and method of manufacture
US6761909B1 (en) * 1999-12-21 2004-07-13 Rxkinetix, Inc. Particulate insulin-containing products and method of manufacture
GB0102075D0 (en) * 2001-01-26 2001-03-14 Astrazeneca Ab Process
FR2824754B1 (fr) * 2001-05-15 2004-05-28 Separex Sa Procede d'obtention de particules solides a partir d'au moins un produit hydrosoluble
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US20070098784A1 (en) 2001-09-28 2007-05-03 Nutraceutix, Inc. Delivery system for biological component
WO2003026687A1 (en) * 2001-09-28 2003-04-03 Nutraceutix, Inc. Delivery system for biological component
US20050048077A1 (en) * 2002-02-21 2005-03-03 George Sachs Compositions, test kits and methods for detecting helicobacter pylori
US6998051B2 (en) * 2002-07-03 2006-02-14 Ferro Corporation Particles from supercritical fluid extraction of emulsion
GB0216780D0 (en) * 2002-07-19 2002-08-28 Bradford Particle Design Ltd Methods of particle formation
US6966990B2 (en) 2002-10-11 2005-11-22 Ferro Corporation Composite particles and method for preparing
US6931888B2 (en) * 2003-02-07 2005-08-23 Ferro Corporation Lyophilization method and apparatus for producing particles
US7083748B2 (en) * 2003-02-07 2006-08-01 Ferro Corporation Method and apparatus for continuous particle production using supercritical fluid
US7455797B2 (en) * 2003-02-28 2008-11-25 Ferro Corporation Method and apparatus for producing particles using supercritical fluid
ES2312996T3 (es) * 2003-04-29 2009-03-01 N.V. Organon Proceso de solidificacion con antidisolvente.
EP1624862B1 (en) 2003-05-08 2014-12-31 Nektar Therapeutics Particulate materials
US20060008531A1 (en) * 2003-05-08 2006-01-12 Ferro Corporation Method for producing solid-lipid composite drug particles
WO2005022603A2 (en) * 2003-09-02 2005-03-10 Integral Technologies, Inc. Low cost conductive containers manufactured from conductive loaded resin-based materials
GB0602637D0 (en) 2006-02-09 2006-03-22 Glaxo Group Ltd Novel process
NL1031224C2 (nl) * 2006-02-23 2007-09-03 Friesland Brands Bv Het bereiden van gedroogde deeltjes met behulp van een superkritisch medium.
US20080095856A1 (en) * 2006-05-12 2008-04-24 Jacobson Gunilla B Encapsulated Nanoparticles for Drug Delivery
FR2900845B1 (fr) * 2006-05-15 2009-03-06 Commissariat Energie Atomique Procede et dispositif de synthese de particules organiques ou inorganiques enrobees
EP1913955A1 (en) 2006-10-19 2008-04-23 Gerhard, Markus Novel method for treating H.pylori infections
US20080260852A1 (en) * 2007-01-23 2008-10-23 Ferro Pfanstiehl Laboratories, Inc. Supercritical fluid extraction produced by in-line homogenization
US7745566B2 (en) * 2007-01-23 2010-06-29 Ferro Corporation Methods for the purification of polymers
MX2009008582A (es) 2007-02-11 2009-10-30 Map Pharmaceuticals Inc Metodo para la administracion terapeutica de dihidroergotamina para permitir un rapido alivio de la migraña mientras se minimiza el perfil de efectos secundarios.
GB0711680D0 (en) 2007-06-18 2007-07-25 Prosonix Ltd Process
EP3272354A1 (en) 2016-07-20 2018-01-24 Technische Universität München Agents and methods for the prevention or treatment of h. pylori infections
KR102170146B1 (ko) * 2019-03-05 2020-10-26 서울대학교산학협력단 Pca 공정을 이용한 배양액의 결정화 장치 및 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639441A (en) * 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation

Also Published As

Publication number Publication date
IL138635A0 (en) 2001-10-31
NO329145B1 (no) 2010-08-30
AR019262A1 (es) 2002-02-13
ID29286A (id) 2001-08-16
SK14112000A3 (sk) 2001-07-10
PL344077A1 (en) 2001-09-24
AU4066399A (en) 1999-11-01
JP2002511400A (ja) 2002-04-16
WO1999052507A1 (en) 1999-10-21
US6372260B1 (en) 2002-04-16
HUP0102305A3 (en) 2003-04-28
CN1309555A (zh) 2001-08-22
KR20010042660A (ko) 2001-05-25
EP1069890A1 (en) 2001-01-24
TW542724B (en) 2003-07-21
NO20005150D0 (no) 2000-10-13
CZ20003784A3 (cs) 2001-08-15
IS5656A (is) 2000-10-11
PT1069890E (pt) 2006-09-29
KR100600691B1 (ko) 2006-07-19
EE200000595A (et) 2002-04-15
ZA992549B (en) 1999-10-14
EP1069890B1 (en) 2006-06-14
DE69931904D1 (de) 2006-07-27
DK1069890T3 (da) 2006-08-28
RU2208435C2 (ru) 2003-07-20
SE9801287D0 (sv) 1998-04-14
CY1105154T1 (el) 2010-03-03
AU744874B2 (en) 2002-03-07
HUP0102305A2 (hu) 2001-12-28
ATE329580T1 (de) 2006-07-15
CA2327522A1 (en) 1999-10-21
TR200002960T2 (tr) 2000-12-21
CA2327522C (en) 2008-03-25
DE69931904T2 (de) 2006-12-21
CN1201728C (zh) 2005-05-18
NO20005150L (no) 2000-12-08
ES2267268T3 (es) 2007-03-01
NZ507190A (en) 2002-02-01

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 9/10, A61K 9/16, A61K 38/00, A61K 39/00, B05B 7/32

Ipc: A61K 9/10 (2009.01), A61K 9/16 (2009.01), A61K 38/

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time