DK0747391T3 - Fremstilling af et acyleret proteinpulver - Google Patents

Fremstilling af et acyleret proteinpulver

Info

Publication number
DK0747391T3
DK0747391T3 DK96303974T DK96303974T DK0747391T3 DK 0747391 T3 DK0747391 T3 DK 0747391T3 DK 96303974 T DK96303974 T DK 96303974T DK 96303974 T DK96303974 T DK 96303974T DK 0747391 T3 DK0747391 T3 DK 0747391T3
Authority
DK
Denmark
Prior art keywords
protein
preparation
protein powder
acylated protein
acylated
Prior art date
Application number
DK96303974T
Other languages
Danish (da)
English (en)
Inventor
Jeffrey Clayton Baker
Brian A Moser
Warren E Schrader
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0747391T3 publication Critical patent/DK0747391T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK96303974T 1995-06-07 1996-05-31 Fremstilling af et acyleret proteinpulver DK0747391T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/484,220 US5700904A (en) 1995-06-07 1995-06-07 Preparation of an acylated protein powder

Publications (1)

Publication Number Publication Date
DK0747391T3 true DK0747391T3 (da) 2004-07-19

Family

ID=23923252

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96303974T DK0747391T3 (da) 1995-06-07 1996-05-31 Fremstilling af et acyleret proteinpulver

Country Status (21)

Country Link
US (1) US5700904A (enExample)
EP (1) EP0747391B1 (enExample)
JP (1) JP3844504B2 (enExample)
KR (1) KR19990022590A (enExample)
CN (1) CN1192218A (enExample)
AT (1) ATE263185T1 (enExample)
AU (1) AU703032B2 (enExample)
BR (1) BR9608729A (enExample)
CA (1) CA2223389A1 (enExample)
CZ (1) CZ388197A3 (enExample)
DE (1) DE69631996T2 (enExample)
DK (1) DK0747391T3 (enExample)
EA (1) EA199800042A1 (enExample)
ES (1) ES2216039T3 (enExample)
HU (1) HUP9900877A3 (enExample)
IL (1) IL122460A0 (enExample)
NO (1) NO975583D0 (enExample)
NZ (1) NZ309371A (enExample)
PL (1) PL323994A1 (enExample)
TR (1) TR199701528T1 (enExample)
WO (1) WO1996040730A1 (enExample)

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US7169889B1 (en) 1999-06-19 2007-01-30 Biocon Limited Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
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US6828305B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
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US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
US7312192B2 (en) 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US6913903B2 (en) 2001-09-07 2005-07-05 Nobex Corporation Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
US7196059B2 (en) 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7166571B2 (en) 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
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AU2003226603A1 (en) * 2002-04-19 2003-11-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disorders
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DE602005016952D1 (de) 2004-10-21 2009-11-12 Novo Nordisk As Wählmechanismus für einen drehstift
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US8007754B2 (en) 2005-02-04 2011-08-30 Mineral And Coal Technologies, Inc. Separation of diamond from gangue minerals
US20090043264A1 (en) 2005-04-24 2009-02-12 Novo Nordisk A/S Injection Device
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US7741281B2 (en) * 2005-11-03 2010-06-22 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
ES2622493T3 (es) 2006-02-24 2017-07-06 Rigel Pharmaceuticals, Inc. Composiciones y métodos para la inhibición de la ruta de JAK
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CN102770152B (zh) 2009-11-25 2016-07-06 阿瑞斯根股份有限公司 肽类的粘膜递送
RU2672100C2 (ru) 2010-07-28 2018-11-12 Райджел Фармасьютикалз, Инк. Композиции и способы ингибирования пути jak
JP6069351B2 (ja) 2011-12-29 2017-02-01 ノボ・ノルデイスク・エー／エス ダイアルアップ／ダイアルダウン投与機構を有するねじりバネ式ねじ巻き自動注射器
EP2828241B1 (en) 2012-03-23 2018-09-12 Mateon Therapeutics, Inc. Compositions and methods for inhibition of cathepsins
US11206846B2 (en) 2017-05-02 2021-12-28 Leprino Foods Company High purity alpha lactalbumin and methods of making
MY200722A (en) 2017-09-26 2024-01-12 Biocon Biologics India Ltd Integrated automated filtration for separation, washing and drying of peptide crystals
US20220000880A1 (en) 2018-11-01 2022-01-06 Rigel Pharmaceuticals, Inc. Method and composition embodiments for treating acute myeloid leukemia
WO2020243612A1 (en) 2019-05-29 2020-12-03 Rigel Pharmaceuticals, Inc. Method of preventing and treating thrombosis
WO2021026451A1 (en) 2019-08-08 2021-02-11 Rigel Pharmaceuticals, Inc. Compounds and method for treating cytokine release syndrome
CN114286679A (zh) 2019-08-14 2022-04-05 里格尔药品股份有限公司 阻断或改善细胞因子释放综合征的方法
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Also Published As

Publication number Publication date
NO975583L (no) 1997-12-03
HUP9900877A3 (en) 1999-11-29
DE69631996D1 (de) 2004-05-06
BR9608729A (pt) 1999-06-29
EA199800042A1 (ru) 1998-08-27
ES2216039T3 (es) 2004-10-16
CZ388197A3 (cs) 1998-05-13
EP0747391A3 (en) 1997-05-21
EP0747391A2 (en) 1996-12-11
CN1192218A (zh) 1998-09-02
EP0747391B1 (en) 2004-03-31
JPH11506738A (ja) 1999-06-15
JP3844504B2 (ja) 2006-11-15
IL122460A0 (en) 1998-06-15
PL323994A1 (en) 1998-04-27
ATE263185T1 (de) 2004-04-15
NO975583D0 (no) 1997-12-03
WO1996040730A1 (en) 1996-12-19
AU5951396A (en) 1996-12-30
NZ309371A (en) 1999-09-29
MX9709657A (es) 1998-07-31
CA2223389A1 (en) 1996-12-19
US5700904A (en) 1997-12-23
HUP9900877A2 (hu) 1999-07-28
AU703032B2 (en) 1999-03-11
DE69631996T2 (de) 2005-01-27
KR19990022590A (ko) 1999-03-25
TR199701528T1 (xx) 1998-03-21

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