ATE241972T1 - Neue stabile flüssige paracetamolmittel und verfahren zu deren herstellung - Google Patents

Neue stabile flüssige paracetamolmittel und verfahren zu deren herstellung

Info

Publication number
ATE241972T1
ATE241972T1 AT97936739T AT97936739T ATE241972T1 AT E241972 T1 ATE241972 T1 AT E241972T1 AT 97936739 T AT97936739 T AT 97936739T AT 97936739 T AT97936739 T AT 97936739T AT E241972 T1 ATE241972 T1 AT E241972T1
Authority
AT
Austria
Prior art keywords
agents
production
stable liquid
new stable
liquid paracetamol
Prior art date
Application number
AT97936739T
Other languages
English (en)
Inventor
Francois Dietlin
Daniele Fredj
Original Assignee
Scr Pharmatop
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9494820&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE241972(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scr Pharmatop filed Critical Scr Pharmatop
Application granted granted Critical
Publication of ATE241972T1 publication Critical patent/ATE241972T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97936739T 1996-08-05 1997-08-05 Neue stabile flüssige paracetamolmittel und verfahren zu deren herstellung ATE241972T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9609858A FR2751875B1 (fr) 1996-08-05 1996-08-05 Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
PCT/FR1997/001452 WO1998005314A1 (fr) 1996-08-05 1997-08-05 Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation

Publications (1)

Publication Number Publication Date
ATE241972T1 true ATE241972T1 (de) 2003-06-15

Family

ID=9494820

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97936739T ATE241972T1 (de) 1996-08-05 1997-08-05 Neue stabile flüssige paracetamolmittel und verfahren zu deren herstellung

Country Status (23)

Country Link
US (1) US6028222A (de)
EP (1) EP0858329B1 (de)
JP (2) JP5060681B2 (de)
KR (1) KR100521235B1 (de)
CN (1) CN1133426C (de)
AP (1) AP957A (de)
AT (1) ATE241972T1 (de)
AU (1) AU742576B2 (de)
BR (1) BR9702362A (de)
CA (1) CA2233924C (de)
CZ (1) CZ298427B6 (de)
DE (1) DE69722580T2 (de)
DK (1) DK0858329T3 (de)
ES (1) ES2201316T3 (de)
FR (1) FR2751875B1 (de)
HU (1) HU226117B1 (de)
MX (1) MX9802734A (de)
NZ (1) NZ330136A (de)
OA (1) OA10678A (de)
PL (1) PL193104B1 (de)
PT (1) PT858329E (de)
RU (1) RU2192249C2 (de)
WO (1) WO1998005314A1 (de)

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FR2779061B1 (fr) * 1998-04-14 2004-08-20 Pharmatop Nouveau procede de stabilisation de composes phenoliques et les compositions pharmaceutiques en resultant
IT1301976B1 (it) 1998-07-31 2000-07-20 Angelini Ricerche Spa Composizione farmaceutica iniettabile a base di paracetamolo
BR0011009B1 (pt) * 1999-05-28 2010-09-21 processo para a fabricação de uma embalagem esterilizada.
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US6334859B1 (en) 1999-07-26 2002-01-01 Zuli Holdings Ltd. Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments
IT1313579B1 (it) * 1999-07-30 2002-09-09 Acraf Composizione farmaceutica liquida a base di paracetamolo.
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FR2809619B1 (fr) * 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
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EP2389931A1 (de) 2010-05-21 2011-11-30 Raw Materials Internatinal LLC Wässrige pharmazeutische Zusammensetzungen mit Liponsäure als Antioxidationsmittel
MX2012014800A (es) * 2010-06-30 2013-01-29 Troikaa Pharmaceuticals Ltd Composiciones farmaceuticas que comprenden paracetamol y proceso para preparar el mismo.
JP5538568B2 (ja) * 2010-12-09 2014-07-02 丸石製薬株式会社 アセトアミノフェンの安定化剤
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CN102600068A (zh) * 2011-01-24 2012-07-25 联康药业克雷恩特塞提斯制药实验室有限责任公司 稳定即用的可注射扑热息痛制剂
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Also Published As

Publication number Publication date
RU2192249C2 (ru) 2002-11-10
ES2201316T3 (es) 2004-03-16
PL326069A1 (en) 1998-08-17
FR2751875A1 (fr) 1998-02-06
US6028222A (en) 2000-02-22
NZ330136A (en) 2000-03-27
CA2233924A1 (fr) 1998-02-12
PT858329E (pt) 2003-09-30
CZ298427B6 (cs) 2007-10-03
HUP9901893A3 (en) 2000-06-28
KR100521235B1 (ko) 2006-01-27
CN1133426C (zh) 2004-01-07
CN1204960A (zh) 1999-01-13
EP0858329A1 (de) 1998-08-19
JP2010163462A (ja) 2010-07-29
JP5122604B2 (ja) 2013-01-16
DK0858329T3 (da) 2003-09-29
OA10678A (fr) 2002-11-20
AP957A (en) 2001-04-12
BR9702362A (pt) 1999-12-28
CZ104898A3 (cs) 1998-09-16
PL193104B1 (pl) 2007-01-31
FR2751875B1 (fr) 1998-12-24
WO1998005314A1 (fr) 1998-02-12
AU742576B2 (en) 2002-01-10
CA2233924C (fr) 2012-08-21
JP5060681B2 (ja) 2012-10-31
DE69722580T2 (de) 2004-04-29
AP9801223A0 (en) 1998-06-30
HU226117B1 (en) 2008-04-28
DE69722580D1 (de) 2003-07-10
JPH11514013A (ja) 1999-11-30
AU3945197A (en) 1998-02-25
HUP9901893A2 (hu) 1999-09-28
KR19990063978A (ko) 1999-07-26
EP0858329B1 (de) 2003-06-04
MX9802734A (es) 1998-11-30

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