AP957A - Novel stable liquid paracetamol compositions, and method for preparing same. - Google Patents

Novel stable liquid paracetamol compositions, and method for preparing same. Download PDF

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Publication number
AP957A
AP957A APAP/P/1998/001223A AP9801223A AP957A AP 957 A AP957 A AP 957A AP 9801223 A AP9801223 A AP 9801223A AP 957 A AP957 A AP 957A
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AP
ARIPO
Prior art keywords
paracetamol
stable
liquid formulations
formulations according
solution
Prior art date
Application number
APAP/P/1998/001223A
Other languages
English (en)
Other versions
AP9801223A0 (en
Inventor
Francois Dietlin
Daniéle Fredj
Original Assignee
Scr Pharmatop
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9494820&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP957(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scr Pharmatop filed Critical Scr Pharmatop
Publication of AP9801223A0 publication Critical patent/AP9801223A0/xx
Application granted granted Critical
Publication of AP957A publication Critical patent/AP957A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
APAP/P/1998/001223A 1996-08-05 1997-08-05 Novel stable liquid paracetamol compositions, and method for preparing same. AP957A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9609858A FR2751875B1 (fr) 1996-08-05 1996-08-05 Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation

Publications (2)

Publication Number Publication Date
AP9801223A0 AP9801223A0 (en) 1998-06-30
AP957A true AP957A (en) 2001-04-12

Family

ID=9494820

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1998/001223A AP957A (en) 1996-08-05 1997-08-05 Novel stable liquid paracetamol compositions, and method for preparing same.

Country Status (23)

Country Link
US (1) US6028222A (de)
EP (1) EP0858329B1 (de)
JP (2) JP5060681B2 (de)
KR (1) KR100521235B1 (de)
CN (1) CN1133426C (de)
AP (1) AP957A (de)
AT (1) ATE241972T1 (de)
AU (1) AU742576B2 (de)
BR (1) BR9702362A (de)
CA (1) CA2233924C (de)
CZ (1) CZ298427B6 (de)
DE (1) DE69722580T2 (de)
DK (1) DK0858329T3 (de)
ES (1) ES2201316T3 (de)
FR (1) FR2751875B1 (de)
HU (1) HU226117B1 (de)
MX (1) MX9802734A (de)
NZ (1) NZ330136A (de)
OA (1) OA10678A (de)
PL (1) PL193104B1 (de)
PT (1) PT858329E (de)
RU (1) RU2192249C2 (de)
WO (1) WO1998005314A1 (de)

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FR2779061B1 (fr) * 1998-04-14 2004-08-20 Pharmatop Nouveau procede de stabilisation de composes phenoliques et les compositions pharmaceutiques en resultant
IT1301976B1 (it) * 1998-07-31 2000-07-20 Angelini Ricerche Spa Composizione farmaceutica iniettabile a base di paracetamolo
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DE19932157A1 (de) * 1999-07-13 2001-01-18 Pharmasol Gmbh Verfahren zur schonenden Herstellung von hochfeinen Mikropartikeln und Nanopartikeln
US6334859B1 (en) 1999-07-26 2002-01-01 Zuli Holdings Ltd. Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments
IT1313579B1 (it) * 1999-07-30 2002-09-09 Acraf Composizione farmaceutica liquida a base di paracetamolo.
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AU2006203741B2 (en) * 2000-06-06 2009-11-05 Scr Pharmatop Method for obtaining aqueous formulations with active principles susceptible to oxidation and the aqueous solutions thus obtained
FR2809619B1 (fr) * 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
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US10022339B2 (en) 2006-04-21 2018-07-17 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
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CN115385818B (zh) * 2022-09-01 2023-09-29 江苏海洋大学 一种扑热息痛杂质及制备方法

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US4314989A (en) * 1980-05-07 1982-02-09 Rosen Gerald M Methionine sulfoxide amflioration of acetaminophen toxicity
US5474757A (en) * 1992-10-16 1995-12-12 Rutgers University Prevention of acetaminophen overdose toxicity with organosulfur compounds

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Publication number Priority date Publication date Assignee Title
US4314989A (en) * 1980-05-07 1982-02-09 Rosen Gerald M Methionine sulfoxide amflioration of acetaminophen toxicity
US5474757A (en) * 1992-10-16 1995-12-12 Rutgers University Prevention of acetaminophen overdose toxicity with organosulfur compounds

Also Published As

Publication number Publication date
OA10678A (fr) 2002-11-20
CA2233924A1 (fr) 1998-02-12
CN1204960A (zh) 1999-01-13
DE69722580D1 (de) 2003-07-10
US6028222A (en) 2000-02-22
RU2192249C2 (ru) 2002-11-10
AP9801223A0 (en) 1998-06-30
DE69722580T2 (de) 2004-04-29
EP0858329A1 (de) 1998-08-19
PT858329E (pt) 2003-09-30
FR2751875B1 (fr) 1998-12-24
JP5060681B2 (ja) 2012-10-31
JPH11514013A (ja) 1999-11-30
HUP9901893A3 (en) 2000-06-28
BR9702362A (pt) 1999-12-28
AU3945197A (en) 1998-02-25
DK0858329T3 (da) 2003-09-29
JP2010163462A (ja) 2010-07-29
PL326069A1 (en) 1998-08-17
CZ104898A3 (cs) 1998-09-16
AU742576B2 (en) 2002-01-10
HU226117B1 (en) 2008-04-28
PL193104B1 (pl) 2007-01-31
FR2751875A1 (fr) 1998-02-06
CZ298427B6 (cs) 2007-10-03
CN1133426C (zh) 2004-01-07
EP0858329B1 (de) 2003-06-04
ATE241972T1 (de) 2003-06-15
MX9802734A (es) 1998-11-30
ES2201316T3 (es) 2004-03-16
HUP9901893A2 (hu) 1999-09-28
KR100521235B1 (ko) 2006-01-27
NZ330136A (en) 2000-03-27
KR19990063978A (ko) 1999-07-26
JP5122604B2 (ja) 2013-01-16
WO1998005314A1 (fr) 1998-02-12
CA2233924C (fr) 2012-08-21

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