AR248085A1 - Procedimiento mejorado para la preparacion de una composicion en microesferas para administracion parenteral en animales. - Google Patents

Procedimiento mejorado para la preparacion de una composicion en microesferas para administracion parenteral en animales.

Info

Publication number
AR248085A1
AR248085A1 AR91319349A AR31934991A AR248085A1 AR 248085 A1 AR248085 A1 AR 248085A1 AR 91319349 A AR91319349 A AR 91319349A AR 31934991 A AR31934991 A AR 31934991A AR 248085 A1 AR248085 A1 AR 248085A1
Authority
AR
Argentina
Prior art keywords
parenteral administration
making same
stable compositions
mixture
fat
Prior art date
Application number
AR91319349A
Other languages
English (en)
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of AR248085A1 publication Critical patent/AR248085A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

UN PROCEDIMIENTO MEJORADO PARA PREPARAR UNA COMPOSICION EN MICROESFERAS QUE COMPRENDE LAS ETAPAS DE MEZCLAR POR FUSION UNA GRASA O CERA O UNA MEZCLA DE LAS MISMAS CON UNA PROTEINA, PEPTIDO O POLIPEPTIDO, BIOLOGICAMENTE ACTIVO Y GRANULAR LA MEZCLA OBTENIDA PARA FORMAR LA COMPOSICION DE MICROESFERAS, QUE COMPRENDE MEZCLAR APROXIMADAMENTE 1% A 30% DE UN ACEITE, UNA GRASA SEMIBLANDA, DE UN PUNTO DE FUSION A O CERCA DE LA TEMPERATURA AMBIENTE, O MEZCLAS DE LOS MISMOS ANTES DE LA GRANULACION DE LA MEZCLA.
AR91319349A 1990-03-30 1991-03-27 Procedimiento mejorado para la preparacion de una composicion en microesferas para administracion parenteral en animales. AR248085A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,382 US5213810A (en) 1990-03-30 1990-03-30 Stable compositions for parenteral administration and method of making same

Publications (1)

Publication Number Publication Date
AR248085A1 true AR248085A1 (es) 1995-06-30

Family

ID=23997559

Family Applications (1)

Application Number Title Priority Date Filing Date
AR91319349A AR248085A1 (es) 1990-03-30 1991-03-27 Procedimiento mejorado para la preparacion de una composicion en microesferas para administracion parenteral en animales.

Country Status (29)

Country Link
US (1) US5213810A (es)
EP (1) EP0448930B1 (es)
JP (1) JP2966564B2 (es)
KR (1) KR0159778B1 (es)
CN (1) CN1063941C (es)
AR (1) AR248085A1 (es)
AT (1) ATE106240T1 (es)
AU (1) AU641994B2 (es)
BG (1) BG60850B1 (es)
CA (1) CA2039491C (es)
CZ (1) CZ283053B6 (es)
DE (1) DE69102176T2 (es)
DK (1) DK0448930T3 (es)
ES (1) ES2054380T3 (es)
FI (1) FI101676B1 (es)
HK (1) HK1000004A1 (es)
HU (1) HU219584B (es)
IE (1) IE65970B1 (es)
IL (1) IL97145A (es)
MX (1) MX172602B (es)
NO (1) NO300717B1 (es)
NZ (1) NZ237509A (es)
PL (1) PL167692B1 (es)
PT (1) PT97160B (es)
RO (1) RO106191B1 (es)
RU (1) RU2011377C1 (es)
SK (1) SK279461B6 (es)
YU (1) YU47650B (es)
ZA (1) ZA912398B (es)

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ATE300285T1 (de) * 1999-06-07 2005-08-15 Altana Pharma Ag Neue zubereitung und darreichungsform enthaltend einen säurelabilen protonenpumpeninhibitor
US6544646B2 (en) 2000-04-27 2003-04-08 Verion Inc. Zero order release and temperature-controlled microcapsules and process for the preparation thereof
TWI268761B (en) * 2000-06-26 2006-12-21 Martek Biosciences Corp Improved methods of incorporating polyunsaturated fatty acids in milk
CA2423484A1 (en) 2000-09-27 2002-04-04 Verion Inc. Instant water dissolvable encapsulate and process
ES2304371T3 (es) * 2000-10-10 2008-10-16 Wyeth Holdings Corporation Composiciones estables para administracion parenteral.
FR2852843B1 (fr) 2003-03-24 2008-05-23 Karim Ioualalen Systeme galenique permettant le masquage du gout
KR20060109481A (ko) * 2003-12-04 2006-10-20 화이자 프로덕츠 인코포레이티드 바람직하게는 폴록사머와 글리세라이드를 함유하는다미립자 아지트로마이신 조성물의 제조를 위해 압출기를사용하는 분무응결 방법
EP1691786A1 (en) * 2003-12-04 2006-08-23 Pfizer Products Inc. Multiparticulate compositions with improved stability
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WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
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BRPI0417348A (pt) * 2003-12-04 2007-03-13 Pfizer Prod Inc processo de gelatinização por spray com utilização de uma extrusora para preparação de composições de droga cristalina multiparticulada contendo preferencialmente um poloxámero e um glicerìdeo
JP2007513146A (ja) * 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 液体系プロセスによるアジスロマイシンマルチパーティキュレート剤形
BRPI0417360A (pt) * 2003-12-04 2007-03-13 Pfizer Prod Inc método para a preparação de multiparticulados farmacêuticos
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US8221809B2 (en) * 2006-06-22 2012-07-17 Martek Biosciences Corporation Encapsulated labile compound compositions and methods of making the same
AU2007284759B2 (en) 2006-08-09 2010-10-28 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
AU2008244523B2 (en) 2007-04-23 2012-02-16 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
BRPI0918904B8 (pt) 2008-09-04 2021-05-25 Amylin Pharmaceuticals Inc formulação pré-misturada fabricada para injeção, seu uso e kit compreendendo a mesma
JP5494957B2 (ja) 2009-06-11 2014-05-21 株式会社リコー 静電荷像現像用トナー、現像剤、画像形成方法及び画像形成装置
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
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US9364549B2 (en) * 2011-11-30 2016-06-14 Andreas Voigt Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
EP3003266A2 (en) * 2013-05-29 2016-04-13 Therakine Biodelivery GmbH Hydrophilic microparticles, drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
EP3302354B1 (en) 2015-06-03 2023-10-04 i2o Therapeutics, Inc. Implant placement systems
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Also Published As

Publication number Publication date
YU47650B (sh) 1995-12-04
HK1000004A1 (en) 1997-10-03
IE65970B1 (en) 1995-11-29
DK0448930T3 (da) 1994-06-20
BG60850B1 (bg) 1996-05-31
AU641994B2 (en) 1993-10-07
AU7397291A (en) 1991-10-03
CA2039491A1 (en) 1991-10-01
KR910016322A (ko) 1991-11-05
FI911531A (fi) 1991-10-01
ES2054380T3 (es) 1994-08-01
ZA912398B (en) 1992-01-29
FI101676B (fi) 1998-08-14
CA2039491C (en) 2001-09-04
HUT59834A (en) 1992-07-28
CZ283053B6 (cs) 1997-12-17
IL97145A (en) 1996-06-18
PL167692B1 (en) 1995-10-31
PT97160B (pt) 1998-07-31
FI101676B1 (fi) 1998-08-14
HU911054D0 (en) 1991-10-28
PT97160A (pt) 1991-11-29
CN1063941C (zh) 2001-04-04
NO911228L (no) 1991-10-01
KR0159778B1 (ko) 1998-12-01
IL97145A0 (en) 1992-05-25
YU57091A (sh) 1994-01-20
PL289657A1 (en) 1992-01-13
HU219584B (hu) 2001-05-28
DE69102176D1 (de) 1994-07-07
MX172602B (es) 1993-01-03
NZ237509A (en) 1993-04-28
IE911041A1 (en) 1991-10-09
ATE106240T1 (de) 1994-06-15
CN1055293A (zh) 1991-10-16
JPH04221319A (ja) 1992-08-11
US5213810A (en) 1993-05-25
RO106191B1 (ro) 1993-03-31
NO300717B1 (no) 1997-07-14
SK279461B6 (sk) 1998-11-04
JP2966564B2 (ja) 1999-10-25
DE69102176T2 (de) 1995-01-05
EP0448930B1 (en) 1994-06-01
RU2011377C1 (ru) 1994-04-30
FI911531A0 (fi) 1991-03-28
NO911228D0 (no) 1991-03-26
EP0448930A1 (en) 1991-10-02

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