PT97160A - Processo para a preparacao de composicoes estaveis para administracao parenterica contendo uma proteina, peptideo ou polipeptideo biologicamente activo - Google Patents

Processo para a preparacao de composicoes estaveis para administracao parenterica contendo uma proteina, peptideo ou polipeptideo biologicamente activo

Info

Publication number
PT97160A
PT97160A PT97160A PT9716091A PT97160A PT 97160 A PT97160 A PT 97160A PT 97160 A PT97160 A PT 97160A PT 9716091 A PT9716091 A PT 9716091A PT 97160 A PT97160 A PT 97160A
Authority
PT
Portugal
Prior art keywords
polypeptide
preparation
biologically active
parenteral administration
active protein
Prior art date
Application number
PT97160A
Other languages
English (en)
Other versions
PT97160B (pt
Inventor
William Steber
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PT97160A publication Critical patent/PT97160A/pt
Publication of PT97160B publication Critical patent/PT97160B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
PT97160A 1990-03-30 1991-03-27 Processo para a preparacao de composicoes estaveis para administracao parenterica contendo uma proteina, peptideo ou polipeptideo biologicamente activo PT97160B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,382 US5213810A (en) 1990-03-30 1990-03-30 Stable compositions for parenteral administration and method of making same

Publications (2)

Publication Number Publication Date
PT97160A true PT97160A (pt) 1991-11-29
PT97160B PT97160B (pt) 1998-07-31

Family

ID=23997559

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97160A PT97160B (pt) 1990-03-30 1991-03-27 Processo para a preparacao de composicoes estaveis para administracao parenterica contendo uma proteina, peptideo ou polipeptideo biologicamente activo

Country Status (29)

Country Link
US (1) US5213810A (pt)
EP (1) EP0448930B1 (pt)
JP (1) JP2966564B2 (pt)
KR (1) KR0159778B1 (pt)
CN (1) CN1063941C (pt)
AR (1) AR248085A1 (pt)
AT (1) ATE106240T1 (pt)
AU (1) AU641994B2 (pt)
BG (1) BG60850B1 (pt)
CA (1) CA2039491C (pt)
CZ (1) CZ283053B6 (pt)
DE (1) DE69102176T2 (pt)
DK (1) DK0448930T3 (pt)
ES (1) ES2054380T3 (pt)
FI (1) FI101676B1 (pt)
HK (1) HK1000004A1 (pt)
HU (1) HU219584B (pt)
IE (1) IE65970B1 (pt)
IL (1) IL97145A (pt)
MX (1) MX172602B (pt)
NO (1) NO300717B1 (pt)
NZ (1) NZ237509A (pt)
PL (1) PL167692B1 (pt)
PT (1) PT97160B (pt)
RO (1) RO106191B1 (pt)
RU (1) RU2011377C1 (pt)
SK (1) SK279461B6 (pt)
YU (1) YU47650B (pt)
ZA (1) ZA912398B (pt)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2086022T3 (es) * 1991-07-23 1996-06-16 American Cyanamid Co Composiciones estables para administracion parenteral y su uso.
AU6029694A (en) * 1993-01-19 1994-08-15 Pharmacia P-L Biochemicals, Inc. Storage and delivery of purified protein reagents with carrier wax
US5599660A (en) * 1993-01-19 1997-02-04 Pharmacia Biotech Inc. Method and preparation for sequential delivery of wax-embedded, inactivated biological and chemical reagents
US5683720A (en) * 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
US6083430A (en) * 1994-10-28 2000-07-04 Fuisz Technologies Ltd. Method of preparing a dosage unit by direct tableting and product therefrom
AU2002300572B2 (en) * 1997-09-19 2004-11-25 Shire Laboratories, Inc. Solid Solution Beadlet
DE69828635T2 (de) * 1997-09-19 2005-06-16 Shire Laboratories, Inc. Feste lösungskügelchen
US6117452A (en) * 1998-08-12 2000-09-12 Fuisz Technologies Ltd. Fatty ester combinations
US8663692B1 (en) * 1999-05-07 2014-03-04 Pharmasol Gmbh Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
CA2369594A1 (en) * 1999-05-07 2000-11-16 Pharmasol Gmbh Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
DE60021570T2 (de) * 1999-06-07 2006-05-24 Altana Pharma Ag Neue zubereitung und darreichungsform enthaltend einen säurelabilen protonenpumpeninhibitor
CA2407154A1 (en) 2000-04-27 2001-11-01 Verion, Inc Zero order release and temperature-controlled microcapsules and process for the preparation thereof
AU2001273028B2 (en) * 2000-06-26 2006-11-16 Dsm Ip Assets B.V. Improved methods of incorporating polyunsaturated fatty acids in milk
AU2001291243A1 (en) 2000-09-27 2002-04-08 Verion Inc. Instant water dissolvable encapsulate and process
ES2304371T3 (es) * 2000-10-10 2008-10-16 Wyeth Holdings Corporation Composiciones estables para administracion parenteral.
FR2852843B1 (fr) 2003-03-24 2008-05-23 Karim Ioualalen Systeme galenique permettant le masquage du gout
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
CA2549225A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions containing preferably a poloxamer and a glyceride
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
EP1691787B1 (en) * 2003-12-04 2008-07-02 Pfizer Products Inc. Method for making pharmaceutical multiparticulates
WO2005053653A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Spray-congeal process using an extruder for preparing multiparticulate azithromycin compositions containing preferably a poloxamer and a glyceride
RU2006119453A (ru) * 2003-12-04 2007-12-20 Пфайзер Продактс Инк. (Us) Получение посредством основанных на применении жидкостей способов лекарственные формы азитромицина с большим количеством частиц
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
BRPI0416534A (pt) * 2003-12-04 2007-01-09 Pfizer Prod Inc composições multiparticuladas com estabilidade melhorada
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US8221809B2 (en) * 2006-06-22 2012-07-17 Martek Biosciences Corporation Encapsulated labile compound compositions and methods of making the same
DK2049081T3 (da) 2006-08-09 2013-02-25 Intarcia Therapeutics Inc Osmotiske leveringssystemer og stempelarrangementer
PT2157967E (pt) 2007-04-23 2013-04-03 Intarcia Therapeutics Inc Formulações de suspensões de péptidos insulinotrópicos e suas utilizações
DK2240155T3 (da) 2008-02-13 2012-09-17 Intarcia Therapeutics Inc Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
CN104248623B (zh) 2008-09-04 2020-04-03 安米林药品有限责任公司 使用非水性载体的持续释放制剂
JP5494957B2 (ja) 2009-06-11 2014-05-21 株式会社リコー 静電荷像現像用トナー、現像剤、画像形成方法及び画像形成装置
KR102148624B1 (ko) 2009-09-28 2020-08-26 인타르시아 세라퓨틱스 인코포레이티드 실질 항정상태 약물 전달의 신속 확립 및/또는 종결
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9364549B2 (en) * 2011-11-30 2016-06-14 Andreas Voigt Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
EP3003266A2 (en) * 2013-05-29 2016-04-13 Therakine Biodelivery GmbH Hydrophilic microparticles, drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
KR20240042548A (ko) 2015-06-03 2024-04-02 인타르시아 세라퓨틱스 인코포레이티드 임플란트 배치 및 제거 시스템들
CN109310743A (zh) 2016-05-16 2019-02-05 因塔西亚制药公司 胰高血糖素受体选择性多肽及其使用方法
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
KR20190104039A (ko) 2017-01-03 2019-09-05 인타르시아 세라퓨틱스 인코포레이티드 Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법
JP2022522114A (ja) * 2019-02-21 2022-04-14 クロマデックス，インコーポレイテッド ニコチンアミドリボシド、ニコチン酸リボシド、還元ニコチニルリボシド化合物、及びニコチニルリボシド化合物誘導体の製剤への使用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147187A (en) * 1962-09-10 1964-09-01 Don Hall Lab Sustained release pharmaceutical
CH637297A5 (fr) * 1978-12-05 1983-07-29 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication.
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
DE3024416C2 (de) * 1980-06-28 1982-04-15 Gödecke AG, 1000 Berlin Verfahren zur Herstellung von Arzneimitteln mit retardierter Wirkstoff-Freisetzung
US4666839A (en) * 1982-12-01 1987-05-19 Amgen Methods and materials for obtaining microbial expression of polypeptides including bovine prolactin
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
US4603044A (en) * 1983-01-06 1986-07-29 Technology Unlimited, Inc. Hepatocyte Directed Vesicle delivery system
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
US4568536A (en) * 1985-02-08 1986-02-04 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
DE3527356A1 (de) * 1985-07-31 1987-02-05 Degussa Verfahren zur verbesserung der fruchtbarkeit von haustieren
SE462894B (sv) * 1985-10-28 1990-09-17 Biogram Ab Mikrokapslar, foerfarande foer framstaellning daerav samt anvaendning
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use
US4911928A (en) * 1987-03-13 1990-03-27 Micro-Pak, Inc. Paucilamellar lipid vesicles

Also Published As

Publication number Publication date
NO300717B1 (no) 1997-07-14
PL289657A1 (en) 1992-01-13
IE911041A1 (en) 1991-10-09
KR0159778B1 (ko) 1998-12-01
US5213810A (en) 1993-05-25
AU641994B2 (en) 1993-10-07
ATE106240T1 (de) 1994-06-15
EP0448930B1 (en) 1994-06-01
KR910016322A (ko) 1991-11-05
RU2011377C1 (ru) 1994-04-30
DE69102176D1 (de) 1994-07-07
ES2054380T3 (es) 1994-08-01
EP0448930A1 (en) 1991-10-02
HUT59834A (en) 1992-07-28
IL97145A0 (en) 1992-05-25
IL97145A (en) 1996-06-18
NZ237509A (en) 1993-04-28
HU219584B (hu) 2001-05-28
CN1055293A (zh) 1991-10-16
SK279461B6 (sk) 1998-11-04
CA2039491A1 (en) 1991-10-01
ZA912398B (en) 1992-01-29
YU57091A (sh) 1994-01-20
RO106191B1 (ro) 1993-03-31
BG93923A (bg) 1993-12-24
CN1063941C (zh) 2001-04-04
FI911531A0 (fi) 1991-03-28
FI101676B (fi) 1998-08-14
HK1000004A1 (en) 1997-10-03
CZ283053B6 (cs) 1997-12-17
IE65970B1 (en) 1995-11-29
FI101676B1 (fi) 1998-08-14
FI911531A (fi) 1991-10-01
AR248085A1 (es) 1995-06-30
BG60850B1 (bg) 1996-05-31
NO911228D0 (no) 1991-03-26
JPH04221319A (ja) 1992-08-11
PL167692B1 (en) 1995-10-31
PT97160B (pt) 1998-07-31
HU911054D0 (en) 1991-10-28
NO911228L (no) 1991-10-01
DE69102176T2 (de) 1995-01-05
AU7397291A (en) 1991-10-03
CA2039491C (en) 2001-09-04
DK0448930T3 (da) 1994-06-20
YU47650B (sh) 1995-12-04
MX172602B (es) 1993-01-03
JP2966564B2 (ja) 1999-10-25

Similar Documents

Publication Publication Date Title
PT97160A (pt) Processo para a preparacao de composicoes estaveis para administracao parenterica contendo uma proteina, peptideo ou polipeptideo biologicamente activo
DE69104777D1 (de) Orale Arzneimittelformen von biologisch aktiven Eiweisstoffen.
FI901102A0 (fi) Farmaceutiska kompositioner.
FI922364A0 (fi) Farmaceutiska kompositioner.
ITRM910696A0 (it) Composizioni farmaceutiche per l'applicazione per via nasale.
FI925615A0 (fi) Stabiliserade farmaceutiska kompositioner, som innehaoller en hmg-coa-reduktas-inhibitorfoerening
SE8903042D0 (sv) Pharmaceutical compositions comprising cyklosporins
LTIP1654A (en) Protein, biologically active hormone, pharmaceutical preparation
IT8621358A0 (it) Composizione farmaceutica adattivita' analgesica.
FI893643A0 (fi) Farmaceutiska kompositioner.
MX9203175A (es) Composicion de implante que contiene un peptido, polipeptido o proteina biologicamente activa y procedimiento para su preparacion.
IT1290797B1 (it) Composizioni farmaceutiche stabilizzate
BR9605046B1 (pt) compostos n-(pirimidinl)-benzenossulfonamida e preparação farmacêutica contendo as mesmas.
FI874414A (fi) Kontrollerat frigoerande farmaceutiska kompositioner.
DK524489D0 (da) Fremgangsmaade til fremstilling af biologisk aktive forbindelser, specielt enzymer
FI901883A0 (fi) Menetelmä terapeuttisesti vaikuttavien 2-substituoitujen N,N'-ditrimetoksibentsoyylipiperatsiinien valmistamiseksi
IL87778A0 (en) Pharmaceutical compositions containing stabilized therapeutically active proteins and their preparation
TR27833A (tr) Antelmintik'lerin uygulanmasina mahsus ''pour-on'' formülasyonu.
IT8721159A0 (it) Amidi di amino tioacetali ciclici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
DE3869939D1 (de) Biologisch wirksame peptide.
DE3585936D1 (de) Biologisch aktive peptide, deren verfahren zur herstellung und pharmazeutische zusammensetzungen.
FI930967A (fi) Substituerade 6,7-dihydroimidazo(1,5,4-ef)(1,5)bensodiazepin-6-oner, deras framstaellning och farmaceutiska kompositioner
DE3782199D1 (de) Biologisch aktive peptide tan-866.
IT8622051A0 (it) Composizioni farmaceutiche adattivita' cicatrizzante.
IT8621925A0 (it) Composizioni farmaceutiche adattivita' antineoplastica.

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910724

FG3A Patent granted, date of granting

Effective date: 19980420

PD3A Change of proprietorship

Free format text: WYETH HOLDINGS CORPORATION US

Effective date: 20031117

TE3A Change of address (patent)

Free format text: AMERICAN CYANAMID COMPANY US

Effective date: 20031117