UA49814C2 - Композиція, яка містить антиген вірусу папіломи, спосіб лікування цервікального раку, спосіб лікування гострокінцевої кондиломи - Google Patents
Композиція, яка містить антиген вірусу папіломи, спосіб лікування цервікального раку, спосіб лікування гострокінцевої кондиломиInfo
- Publication number
- UA49814C2 UA49814C2 UA97063426A UA97063426A UA49814C2 UA 49814 C2 UA49814 C2 UA 49814C2 UA 97063426 A UA97063426 A UA 97063426A UA 97063426 A UA97063426 A UA 97063426A UA 49814 C2 UA49814 C2 UA 49814C2
- Authority
- UA
- Ukraine
- Prior art keywords
- curing method
- papilome
- condilome
- acute
- composition containing
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 238000001723 curing Methods 0.000 title 2
- 206010008342 Cervix carcinoma Diseases 0.000 title 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- 230000001154 acute effect Effects 0.000 title 1
- 201000010881 cervical cancer Diseases 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 230000003292 diminished effect Effects 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
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- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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- A—HUMAN NECESSITIES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/80—Vaccine for a specifically defined cancer
- A61K2039/892—Reproductive system [uterus, ovaries, cervix, testes]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
Abstract
Запропоновані способи і сполуки, корисні для розвитку циклотоксичного Т-лімфоцитного (ЦТЛ) імунного відгуку людини, або домашніх чи важливих для сільського господарства тварин. Цей спосіб передбачає стадії надання антигену, для якого відгук ЦТЛ є бажаним, і створення сполуки антигену, яка містить, складається чи вироблена по суті з двох чи більше речовин типу стабілізуючого детергенту, агенту, що утворює міцелу, і олії. Така сполука антигену у бажаному випадку не містить компоненти імуностабілізуючого пептиду, або має достатньо низький вміст такого компоненту для того, щоб не зменшити бажаний відгук ЦТЛ. Така сполука являє собою стійку емульсію типу розчину олії у воді.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/351,001 US5709860A (en) | 1991-07-25 | 1994-12-07 | Induction of cytotoxic T-lymphocyte responses |
PCT/US1995/015433 WO1996017863A1 (en) | 1994-12-07 | 1995-11-29 | Induction of cytotoxic t-lymphocyte responses |
Publications (1)
Publication Number | Publication Date |
---|---|
UA49814C2 true UA49814C2 (uk) | 2002-10-15 |
Family
ID=23379172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA97063426A UA49814C2 (uk) | 1994-12-07 | 1995-11-29 | Композиція, яка містить антиген вірусу папіломи, спосіб лікування цервікального раку, спосіб лікування гострокінцевої кондиломи |
Country Status (33)
Country | Link |
---|---|
US (2) | US5709860A (uk) |
EP (1) | EP0801656A4 (uk) |
JP (1) | JPH10510264A (uk) |
CN (2) | CN1109046C (uk) |
AP (1) | AP661A (uk) |
AR (1) | AR002255A1 (uk) |
AU (1) | AU699044B2 (uk) |
BG (1) | BG63262B1 (uk) |
BR (1) | BR9509872A (uk) |
CA (1) | CA2204738A1 (uk) |
CZ (1) | CZ293439B6 (uk) |
EE (1) | EE03569B1 (uk) |
FI (1) | FI972431A0 (uk) |
GE (1) | GEP20012556B (uk) |
HK (1) | HK1008226A1 (uk) |
HU (1) | HUP9800946A2 (uk) |
IS (1) | IS4479A (uk) |
LT (1) | LT4308B (uk) |
LV (1) | LV11866B (uk) |
MD (1) | MD1586G2 (uk) |
MX (1) | MX9704097A (uk) |
NO (1) | NO972521L (uk) |
NZ (1) | NZ298582A (uk) |
OA (1) | OA10736A (uk) |
PL (1) | PL183954B1 (uk) |
RO (1) | RO120065B1 (uk) |
RU (1) | RU2201253C2 (uk) |
SI (1) | SI9520148A (uk) |
SK (1) | SK71397A3 (uk) |
TJ (1) | TJ384B (uk) |
TW (1) | TW487575B (uk) |
UA (1) | UA49814C2 (uk) |
WO (1) | WO1996017863A1 (uk) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6197311B1 (en) * | 1991-07-25 | 2001-03-06 | Idec Pharmaceuticals Corporation | Induction of cytotoxic T-lymphocyte responses |
EP0671926B1 (en) * | 1992-08-11 | 2002-11-13 | President And Fellows Of Harvard College | Immunomodulatory peptides |
MY131805A (en) * | 1997-09-18 | 2007-09-28 | Biogen Idec Inc | Synergistic composition and methods for treating neoplastic or cancerous growths and for restoring or boosting hematopoiesis. |
US6183746B1 (en) | 1997-10-09 | 2001-02-06 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
US6013258A (en) * | 1997-10-09 | 2000-01-11 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
FR2771640B1 (fr) | 1997-12-03 | 2000-02-11 | Inst Nat Sante Rech Med | Micelles mixtes de lipopeptides pour l'induction d'une reponse immunitaire et leurs utilisations a des fins therapeutiques |
JP4375773B2 (ja) * | 1998-04-20 | 2009-12-02 | 塩野義製薬株式会社 | W/Oエマルジョンを含有するTh2移行促進剤 |
US20010033839A1 (en) * | 1999-10-04 | 2001-10-25 | Emilio Barbera-Guillem | Vaccine and immunotherapy for solid nonlymphoid tumor and related immune dysregulation |
CN1197150C (zh) | 1999-02-18 | 2005-04-13 | 精工爱普生株式会社 | 半导体装置、安装基板及其制造方法、电路基板和电子装置 |
WO2000056361A2 (en) * | 1999-03-24 | 2000-09-28 | The Secretary Of State For Defence | Vaccine composition |
US20050100928A1 (en) * | 1999-09-16 | 2005-05-12 | Zycos Inc., A Delaware Corporation | Nucleic acids encoding polyepitope polypeptides |
FR2805163A1 (fr) * | 2000-02-21 | 2001-08-24 | Pf Medicament | Utilisation d'un detergent de type zwittergent pour la preparation d'une composition pharmaceutique destinee a etre administree par voie nasale |
WO2001098206A1 (en) * | 2000-06-22 | 2001-12-27 | Rxkinetix, Inc. | Delivery vehicle composition and methods for delivering antigens and other drugs |
FR2814957B1 (fr) * | 2000-10-06 | 2002-12-20 | Aventis Pasteur | Composition vaccinale et procede de stabilisation |
AU2003253632A1 (en) * | 2002-06-10 | 2003-12-22 | Idec Pharmaceuticals Corporation | Genes overexpressed by ovarian cancer and their use in developing novel therapeutics |
WO2004012751A1 (ja) * | 2002-08-02 | 2004-02-12 | Sumitomo Pharmaceuticals Company, Limited | 細菌細胞壁骨格成分製剤 |
EP1545575A4 (en) | 2002-09-19 | 2006-04-05 | Us Gov Health & Human Serv | POLYPEPTIDES OF P. ARIASI POLYPEPTIDES P. PERNICIOSUS AND METHODS OF USE |
CA2502696A1 (en) * | 2002-10-21 | 2004-05-06 | Mgi Pharma Biologics, Inc. | Compositions and methods for treating human papillomavirus-mediated disease |
WO2004039958A2 (en) | 2002-10-29 | 2004-05-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Lutzomyia longipalpis polypeptides and methods of use |
EP1741438A4 (en) * | 2004-04-22 | 2009-08-26 | Dainippon Sumitomo Pharma Co | PHARMACEUTICAL PREPARATION CONTAINING SKELETAL COMPONENT OF BACTERIAL CELL WALL |
EP1942932B1 (en) | 2005-08-08 | 2013-05-08 | Oregon Health and Science University | Inactivating pathogens with hydrogen peroxide for vaccine production |
US20100130425A1 (en) | 2005-09-09 | 2010-05-27 | Oregon Health & Science University | Use of toll-like receptor ligands in treating excitotoxic injury, ischemia and/or hypoxia |
US7732166B2 (en) * | 2005-11-15 | 2010-06-08 | Oncohealth Corporation | Detection method for human pappilomavirus (HPV) and its application in cervical cancer |
EP2207035B1 (en) | 2006-03-14 | 2013-10-16 | Oregon Health and Science University | Methods for detecting a mycobacterium tuberculosis infection |
JP2009536818A (ja) | 2006-04-20 | 2009-10-22 | ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド | 志賀毒性1型タンパク質に基づく方法および組成物 |
US8968995B2 (en) * | 2008-11-12 | 2015-03-03 | Oncohealth Corp. | Detection, screening, and diagnosis of HPV-associated cancers |
US8859218B2 (en) * | 2008-06-13 | 2014-10-14 | Oncohealth Corp. | In situ detection of early stages and late stages HPV infection |
CA2678404C (en) | 2007-02-28 | 2019-03-19 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Brachyury polypeptides and methods for use |
EP2324049B1 (en) | 2008-08-04 | 2016-05-25 | The Government of the U.S.A. as represented by The Secretary of the dept. of Health & Human Services | Membrane proximal region of hiv gp41 anchored to the lipid layer of a virus-like particle vaccine |
WO2010099472A2 (en) | 2009-02-27 | 2010-09-02 | The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services | Spanx-b polypeptides and their use |
EP2427763A4 (en) | 2009-05-07 | 2013-08-21 | Oncohealth Corp | IDENTIFICATION OF HIGH GRADE OR CIN2 FOR DETECTION, MONITORING AND DIAGNOSIS, AT EARLY STAGES AND ADVANCED STAGES, OF HUMAN PAPILLOMAVIRUS (HPV) AND HPV ASSOCIATED CANCERS |
BR112012009401A2 (pt) | 2009-10-07 | 2017-02-21 | Uvic Ind Partnerships Inc | vacinas que compreendem transgenes sensíveis ao calor |
US9181306B2 (en) | 2009-10-16 | 2015-11-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Insertion of foreign genes in rubella virus and their stable expression in a live, attenuated viral vaccine |
US8961989B2 (en) | 2009-11-20 | 2015-02-24 | Oregon Health & Science University | Methods for producing an immune response to tuberculosis |
US9128094B2 (en) | 2010-01-08 | 2015-09-08 | Oncohealth Corp. | High throughput cell-based HPV immunoassays for diagnosis and screening of HPV-associated cancers |
WO2011112599A2 (en) | 2010-03-12 | 2011-09-15 | The United States Of America, As Represented By The Secretary. Department Of Health & Human Services | Immunogenic pote peptides and methods of use |
WO2011119920A2 (en) | 2010-03-25 | 2011-09-29 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
CN102125698A (zh) * | 2010-11-29 | 2011-07-20 | 昆明理工大学 | 具有正常免疫功能的小鼠移植肿瘤模型的建立方法 |
CA2832109C (en) | 2011-06-10 | 2021-07-06 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
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- 1995-11-29 JP JP51764196A patent/JPH10510264A/ja not_active Ceased
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- 1995-11-29 BR BR9509872A patent/BR9509872A/pt not_active Application Discontinuation
- 1995-11-29 CN CNA031088449A patent/CN1515319A/zh active Pending
- 1995-11-29 AP APAP/P/1997/001056A patent/AP661A/en active
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