AR245219A1 - Acido nucleico que codifica linfotoxina de secuencias de aminoacidos humana. - Google Patents

Acido nucleico que codifica linfotoxina de secuencias de aminoacidos humana.

Info

Publication number
AR245219A1
AR245219A1 AR86305572A AR30557286A AR245219A1 AR 245219 A1 AR245219 A1 AR 245219A1 AR 86305572 A AR86305572 A AR 86305572A AR 30557286 A AR30557286 A AR 30557286A AR 245219 A1 AR245219 A1 AR 245219A1
Authority
AR
Argentina
Prior art keywords
human amino
amino acid
nucleic acid
acid sequences
codes human
Prior art date
Application number
AR86305572A
Other languages
English (en)
Spanish (es)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/616,502 external-priority patent/US4959457A/en
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of AR245219A1 publication Critical patent/AR245219A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C07K16/242—Lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C07K14/5255—Lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AR86305572A 1984-05-31 1986-10-14 Acido nucleico que codifica linfotoxina de secuencias de aminoacidos humana. AR245219A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61650384A 1984-05-31 1984-05-31
US06/616,502 US4959457A (en) 1984-05-31 1984-05-31 Anti-lymphotoxin
US73231285A 1985-05-09 1985-05-09

Publications (1)

Publication Number Publication Date
AR245219A1 true AR245219A1 (es) 1993-12-30

Family

ID=27417179

Family Applications (1)

Application Number Title Priority Date Filing Date
AR86305572A AR245219A1 (es) 1984-05-31 1986-10-14 Acido nucleico que codifica linfotoxina de secuencias de aminoacidos humana.

Country Status (23)

Country Link
EP (2) EP0509553B1 (forum.php)
JP (3) JP2521703B2 (forum.php)
AR (1) AR245219A1 (forum.php)
AT (2) ATE95243T1 (forum.php)
AU (1) AU599303B2 (forum.php)
BG (1) BG60256B2 (forum.php)
CA (1) CA1340641C (forum.php)
CZ (1) CZ283148B6 (forum.php)
DE (2) DE3587597T2 (forum.php)
DK (1) DK171531B1 (forum.php)
ES (1) ES8802182A1 (forum.php)
FI (1) FI93025C (forum.php)
GR (1) GR851317B (forum.php)
HU (1) HU204085B (forum.php)
IE (1) IE63487B1 (forum.php)
IL (1) IL75318A (forum.php)
NO (1) NO179075C (forum.php)
NZ (1) NZ212207A (forum.php)
PL (1) PL155410B1 (forum.php)
PT (1) PT80573B (forum.php)
RO (1) RO100383A2 (forum.php)
SK (1) SK278333B6 (forum.php)
YU (1) YU47735B (forum.php)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE56471T1 (de) 1980-04-03 1990-09-15 Biogen Inc Dns-sequenzen, rekombinante dns-molekuele und verfahren zur herstellung von dem menschlichen fibroblast-interferon.
NZ212207A (en) 1984-05-31 1991-07-26 Genentech Inc Recombinant lymphotoxin
US5683688A (en) 1984-05-31 1997-11-04 Genentech, Inc. Unglycosylated recombinant human lymphotoxin polypeptides and compositions
IL73883A (en) * 1984-12-20 1990-12-23 Yeda Res & Dev Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha
JP2557053B2 (ja) * 1984-12-21 1996-11-27 バイオジェン インコーポレイテッド 腫瘍壊死因子の精製、製造および使用法
AU603768B2 (en) * 1985-07-04 1990-11-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Lymphotoxin dna, lymphotoxin expression vector, lymphotoxin resistant cell, transformant with lymphotoxin expression vector and process for preparing lymphotoxin
JPS62111928A (ja) * 1985-10-15 1987-05-22 Kanegafuchi Chem Ind Co Ltd 新規リンホトキシン
JPS62195285A (ja) * 1986-02-19 1987-08-28 Kanegafuchi Chem Ind Co Ltd リンホトキシン発現ベクタ−及びそれを用いるリンホトキシンの製造方法
JP2548204B2 (ja) * 1987-06-27 1996-10-30 電気化学工業株式会社 新生理活性ポリペプチド
EP0230781B1 (en) * 1985-12-24 1992-07-22 Denki Kagaku Kogyo Kabushiki Kaisha Lymphotoxin gene, method for its production, and lymphotoxin
US5403725A (en) * 1985-12-24 1995-04-04 Denki Kagaku Kogyo Kabushiki Kaisha Method for production of lymphotoxin (TNFB) in cell line A-C5-8
EP0230574A3 (en) * 1986-01-31 1989-03-22 Yale University Pharmaceutical compositions against infections caused by lav/htlv iii virus and the use thereof
JPS62181298A (ja) * 1986-02-05 1987-08-08 Kyowa Hakko Kogyo Co Ltd ヒトリンホトキシンポリペプチド誘導体
DE3620656A1 (de) * 1986-06-20 1987-12-23 Basf Ag Polypeptide mit lymphotoxin-aktivitaet oder lymphotoxin-aehnlicher aktivitaet, ihre herstellung und verwendung
JPS63105680A (ja) * 1986-10-22 1988-05-10 Kanegafuchi Chem Ind Co Ltd ヒト・リンホトキシン発現ベクタ−、該発現ベクタ−による形質転換細胞および該細胞を用いるリンホトキシンの製造方法
EP0272894A3 (en) * 1986-12-24 1989-06-14 Takeda Chemical Industries, Ltd. Recombinant human lymphotoxin
US5175268A (en) * 1986-12-24 1992-12-29 Takeda Chemical Industries, Ltd. DNA encoding recombinant human lymphotoxin
FI884798A7 (fi) * 1987-10-28 1989-04-29 Eisai Co Ltd Rekombinantlymfotoxin.
DE3837012A1 (de) * 1988-01-15 1989-07-27 Knoll Ag Verwendung von tnf und lt zur herstellung von arzneimitteln
GB2217326B (en) * 1988-04-08 1991-11-20 British Bio Technology Synthetic gene encoding human tumour necrosis factor beta.
EP0338497A3 (en) * 1988-04-22 1990-05-16 Takeda Chemical Industries, Ltd. Bispecific hybrid monoclonal antibody
JPH023698A (ja) * 1988-06-20 1990-01-09 Denki Kagaku Kogyo Kk ヒトリンホトキシンに対するモノクローナル抗体及びそれら抗体を産生するハイブリドーマ、並びにそれら抗体を用いたヒトリンホトキシンの精製方法、測定方法及び測定試薬
CA2001756A1 (en) * 1988-10-31 1991-04-30 Seiichi Uesugi New human lymphotoxin n-end deletion mutant
JPH03106821A (ja) * 1989-09-20 1991-05-07 Denki Kagaku Kogyo Kk 抗腫瘍剤
US5370870A (en) * 1989-10-06 1994-12-06 Genentech, Inc. Method for protection against reactive oxygen species
US5200176A (en) * 1989-10-06 1993-04-06 Genentech, Inc. Method for protection of ischemic tissues using tumor nerosis factor
IL97779A (en) * 1990-04-10 2000-01-31 Genentech Inc Compositions for cytoprotection against radiation and chemotherapy injury or risk thereof
US5747023A (en) * 1994-07-01 1998-05-05 Genentech, Inc. Cancer therapy using lymphotoxin
CA2210484C (en) * 1995-01-23 2012-12-04 Xenotech Incorporated Composition to ameliorate osteolysis and metastasis
US5925351A (en) 1995-07-21 1999-07-20 Biogen, Inc. Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
US6998116B1 (en) 1996-01-09 2006-02-14 Genentech, Inc. Apo-2 ligand
WO1999036535A1 (en) 1998-01-15 1999-07-22 Genentech, Inc. Apo-2 ligand
US20070048301A1 (en) * 2002-11-26 2007-03-01 Bodary-Winter Sarah C Compositions and methods for the treatment of immune related diseases
WO2005000899A2 (en) 2003-06-27 2005-01-06 Biogen Idec Ma Inc. Modified binding molecules comprising connecting peptides
EP1699486A4 (en) * 2003-12-08 2007-07-18 Centocor Inc ANTI-LYMPHOTOXIN HUMAN ALPHA ANTIBODIES, COMPOSITIONS, METHODS AND USES
EP1756162A1 (en) 2004-03-23 2007-02-28 Biogen Idec MA Inc. Receptor coupling agents and therapeutic uses thereof
WO2006074399A2 (en) 2005-01-05 2006-07-13 Biogen Idec Ma Inc. Multispecific binding molecules comprising connecting peptides
BRPI0715580A2 (pt) * 2006-10-12 2014-06-10 Genentech Inc ''ANTICORPO ANTI-LINFOTOXINA-a (LTa) ISOLADO, ANTICORPO HUMANIZADO, ANTICORPOS ANTI-LINFOTOXINA-a,COMPOSIÇÃO DE ANTICORPO,ANTICORPO ANTI-IDIOTIPO,HIBRIDOMA,ANTICORPO,ÁCIDO NUCLÉICO ISOLADO, VETOR DE EXPRESSÃO,CÉLULA HOSPEDEIRA,MÉTODO DE PRODUÇÃO DE UM ANTICORPO,MÉTODO PARA INIBIR A PROLIFERAÇÃO CELULAR ATIVADA POR LTa, MÉTODO PARA TRATAR UM DISTURBIO AUTO-IMUNE, ARTIGOS MANUFATURADOS, MÉTODO PARA DIVULGAR UM ANTICORPO E MÉTODO PARA EMBALAR O ANTICORPO''
US8338376B2 (en) 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
SG178002A1 (en) 2006-10-20 2012-02-28 Biogen Idec Inc Treatment of demyelinating disorders
CN112716890A (zh) * 2014-04-25 2021-04-30 诺雷克斯股份有限公司 神经活性肽的稳定组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR73675B (forum.php) * 1978-12-22 1984-03-29 Biogen Inc
NZ201918A (en) 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
ZA834976B (en) * 1982-07-30 1984-08-29 Genentech Inc Human lymphotoxin
IE56026B1 (en) 1982-10-19 1991-03-27 Cetus Corp Cysteine-depleted muteins of biologically active proteins
DE3331108A1 (de) * 1983-08-30 1985-05-02 Boehringer Ingelheim International GmbH, 6507 Ingelheim Verfahren zur herstellung von lymphotoxin und von lymphotoxin-mrna
EP0135797A3 (de) * 1983-08-30 1987-11-11 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verfahren zur Herstellung von Lymphotoxin und von Lymphotoxin-mRNA
NZ212207A (en) 1984-05-31 1991-07-26 Genentech Inc Recombinant lymphotoxin

Also Published As

Publication number Publication date
AU4320385A (en) 1985-12-05
BG60256B1 (bg) 1994-03-24
NO852173L (no) 1985-12-02
DE3588225T2 (de) 2001-04-05
JPS6156197A (ja) 1986-03-20
JPH07250692A (ja) 1995-10-03
IE930589L (en) 1985-11-30
EP0509553B1 (en) 2000-08-09
NO179075C (no) 1996-07-31
CA1340641C (en) 1999-07-13
ATE95243T1 (de) 1993-10-15
DE3587597T2 (de) 1994-06-01
PT80573B (pt) 1987-08-19
JP2521703B2 (ja) 1996-08-07
FI93025B (fi) 1994-10-31
CZ283148B6 (cs) 1998-01-14
IL75318A (en) 1994-08-26
PL155410B1 (en) 1991-11-29
RO100383B1 (ro) 1991-03-01
YU47735B (sh) 1996-01-08
FI852143A0 (fi) 1985-05-29
PL253739A1 (en) 1986-03-11
NZ212207A (en) 1991-07-26
JP2804237B2 (ja) 1998-09-24
NO179075B (no) 1996-04-22
IL75318A0 (en) 1985-09-29
RO100383A2 (ro) 1991-10-17
DK171531B1 (da) 1996-12-23
CZ393085A3 (en) 1997-07-16
DE3587597D1 (de) 1993-11-04
ES543695A0 (es) 1988-04-16
ES8802182A1 (es) 1988-04-16
DK241385A (da) 1985-12-01
IE851321L (en) 1985-11-30
EP0509553A1 (en) 1992-10-21
ATE195323T1 (de) 2000-08-15
BG60256B2 (bg) 1994-03-24
JPH07291995A (ja) 1995-11-07
HUT37814A (en) 1986-02-28
GR851317B (forum.php) 1985-11-25
EP0164965A3 (en) 1988-04-06
FI852143L (fi) 1985-12-01
PT80573A (en) 1985-06-01
DE3588225D1 (de) 2000-09-14
EP0164965A2 (en) 1985-12-18
DK241385D0 (da) 1985-05-30
SK393085A3 (en) 1996-11-06
SK278333B6 (en) 1996-11-06
EP0164965B1 (en) 1993-09-29
FI93025C (fi) 1995-02-10
HU204085B (en) 1991-11-28
YU91985A (en) 1988-12-31
IE63487B1 (en) 1995-05-03
AU599303B2 (en) 1990-07-19

Similar Documents

Publication Publication Date Title
AR245219A1 (es) Acido nucleico que codifica linfotoxina de secuencias de aminoacidos humana.
GB8305786D0 (en) Human antithrombim iii dna sequences
EP0157280A3 (en) Dna sequencing
GB2155176B (en) Sequencing dna
EP0259498A4 (en) STRIP CODE LABEL.
GB2217636B (en) Bending tool assembly.
DE3576524D1 (de) Dna-sequenzen.
GB8626914D0 (en) Dna clone
EP0424459A4 (en) Dna encoding human monoamine oxidase type a
EP0256804A3 (en) Code reader
AU2245888A (en) Code reader
GB8610230D0 (en) Dna segment coding
GB8703703D0 (en) Reading bar code
GB2135677B (en) Plasmids comprising sequences which code for trna
GB2211051B (en) Code correlation arrangement
EP0191854A4 (en) ANTI-VIRAL PEPTIDES.
GB8528449D0 (en) Bar code reading system
EP0312346A3 (en) E. coli sequence specific acid protease
GB8627123D0 (en) Dna sequence
GB8424027D0 (en) Bar code readers
GB2212160B (en) Dna sequences encoding the bspmi recognition site.
GB8716938D0 (en) Dna sequence coding
GB8629633D0 (en) Bar code wands
GB8429099D0 (en) Closed dna sequences
HUT38457A (en) Bar code reader