AR104176A1 - Inhibidores de ido (indolamina-2,3-dioxigenasa) - Google Patents

Inhibidores de ido (indolamina-2,3-dioxigenasa)

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Publication number
AR104176A1
AR104176A1 ARP160100897A ARP160100897A AR104176A1 AR 104176 A1 AR104176 A1 AR 104176A1 AR P160100897 A ARP160100897 A AR P160100897A AR P160100897 A ARP160100897 A AR P160100897A AR 104176 A1 AR104176 A1 AR 104176A1
Authority
AR
Argentina
Prior art keywords
optionally substituted
cycloalkyl
alkyl
heteroaryl
heterocyclyl
Prior art date
Application number
ARP160100897A
Other languages
English (en)
Spanish (es)
Inventor
Pulicharla Nagalakshmi
Kanyaboina Yadagiri
Thangathirupathy Srinivasan
Cheruku Srinivas
Kumar Sistla Ramesh
Thangavel Soodamani
Roy Saumya
Jethanand Nara Susheel
Murugesan Natesan
K Williams David
Shan Weifang
P Seitz Steven
A Markwalder Jay
Huang Audris
Guo Weiwei
Charlotte Cherney Emily
Aaron Balog James
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of AR104176A1 publication Critical patent/AR104176A1/es

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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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