AR092645A1 - Derivados biciclicos inhibidores de autotaxina (atx) - Google Patents

Derivados biciclicos inhibidores de autotaxina (atx)

Info

Publication number
AR092645A1
AR092645A1 ARP130103396A ARP130103396A AR092645A1 AR 092645 A1 AR092645 A1 AR 092645A1 AR P130103396 A ARP130103396 A AR P130103396A AR P130103396 A ARP130103396 A AR P130103396A AR 092645 A1 AR092645 A1 AR 092645A1
Authority
AR
Argentina
Prior art keywords
substituted
thiophenyl
quinoline
alkyl
cycloalkyl
Prior art date
Application number
ARP130103396A
Other languages
English (en)
Spanish (es)
Inventor
Hunziker Daniel
Hert Jerme
Mauser Harald
Tang Guozhi
Wang Lisha
Mattei Patrizio
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR092645A1 publication Critical patent/AR092645A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ARP130103396A 2012-09-25 2013-09-23 Derivados biciclicos inhibidores de autotaxina (atx) AR092645A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12185941 2012-09-25

Publications (1)

Publication Number Publication Date
AR092645A1 true AR092645A1 (es) 2015-04-29

Family

ID=47073290

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130103396A AR092645A1 (es) 2012-09-25 2013-09-23 Derivados biciclicos inhibidores de autotaxina (atx)

Country Status (32)

Country Link
US (4) US20150353559A1 (instruction)
EP (2) EP2900669B1 (instruction)
JP (1) JP6285444B2 (instruction)
KR (1) KR102179599B1 (instruction)
CN (1) CN104684915B (instruction)
AR (1) AR092645A1 (instruction)
AU (1) AU2013322838B2 (instruction)
BR (1) BR112015004111A2 (instruction)
CA (1) CA2878442A1 (instruction)
CL (1) CL2015000706A1 (instruction)
CR (1) CR20150120A (instruction)
DK (1) DK2900669T3 (instruction)
EA (1) EA036630B1 (instruction)
ES (1) ES2753163T3 (instruction)
HR (1) HRP20191937T1 (instruction)
HU (1) HUE045797T2 (instruction)
IL (1) IL237126A (instruction)
IN (1) IN2015DN00960A (instruction)
LT (1) LT2900669T (instruction)
MA (1) MA37940B1 (instruction)
MX (1) MX368615B (instruction)
PE (1) PE20150758A1 (instruction)
PH (1) PH12015500263B1 (instruction)
PL (1) PL2900669T3 (instruction)
PT (1) PT2900669T (instruction)
RS (1) RS59512B1 (instruction)
SG (1) SG11201500572YA (instruction)
SI (1) SI2900669T1 (instruction)
TW (1) TWI609018B (instruction)
UA (1) UA116547C2 (instruction)
WO (1) WO2014048865A1 (instruction)
ZA (1) ZA201500345B (instruction)

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