AR076798A1 - Pirazinilpirazoles y composiciones que comprenden dichos compuestos - Google Patents
Pirazinilpirazoles y composiciones que comprenden dichos compuestosInfo
- Publication number
- AR076798A1 AR076798A1 ARP100101827A ARP100101827A AR076798A1 AR 076798 A1 AR076798 A1 AR 076798A1 AR P100101827 A ARP100101827 A AR P100101827A AR P100101827 A ARP100101827 A AR P100101827A AR 076798 A1 AR076798 A1 AR 076798A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- haloalkyl
- alkoxy
- halogen
- polysubstituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Se desvelan pirazin-2-ilpirazoles, como en el uso de los mismos como insecticidas y/o parasiticidas. Además, se describen procedimientos para su preparacion y composiciones que comprenden dichos pirazin-2-ilpirazoles. Reivindicacion 1: Pirazinilpirazoles de formula general (1) en la que X es fenilo, 2-piridilo o 3-piridilo, cada uno de los cuales está sustituido con uno o más sustituyentes seleccionados entre el grupo constituido por halogeno, alquilo, haloalquilo, alcoxi, alcoxialquilo, alcoxialcoxi, cicloalquilo, alqueniloxi, alquiniloxi, benciloxi, cicloalquilalcoxi, haloalcoxi, haloalcoxialquilo, alquilsulfanilo, haloalquilsulfanilo, alquilsulfinilo, haloalquilsulfinilo, alquilsulfonilo, haloalquilsulfonilo, ciano, nitro, alquilcarbonilo, alcoxicarbonilo, alcoxicarbonilalquilo, carboxilo, carboxamida, dialquilcarboxamida, trialquilsililo, amino, alquilamino, dialquilamino, aIquilsulfonilamino, dialquilsulfonilamino, formilo, -CH=NO-H, -CH=NO-alquilo, -CH=NO-haloalquilo, -C(CH3)=NO-H, -C(CH3)=NO-alquilo, -C(CH3)=NO-haloalquilo; o fenilo, 2-piridilo y 3-piridilo opcionalmente sustituido con uno o más átomos de halogeno, ciano, nitro, alquilo, alcoxi o haloalquilo, donde los grupos alquilo, haloalquilo, alcoxi y/o haloalcoxi vecinos en el sustituyente fenilo, el sustituyente 2-piridilo o el sustituyente 3-piridilo, junto con los átomos de carbono a los que están unidos, pueden formar un sistema cíclico de cinco a siete miembros que contiene de 0 a 2 átomos de oxígeno o nitrogeno, donde dos átomos de oxígeno no están unidos directamente entre sí, y cuyo resto alquilo puede estar opcionalmente sustituido con uno o más átomos de halogeno y/o radicales alquilo adicionales; R1 es hidrogeno, alquilo que está opcionalmente mono- o independientemente polisustituido con alcoxi, haloalcoxi, alquilsulfanilo, haloalquilsulfanilo, alquilsulfinilo, haloalquilsulfinilo, alquilsulfonilo, haloalquilsulfonilo, alquilcarbonilo, alcoxicarbonilo, hidroxilo y/o cicloalquilo; alquenilo que está opcionalmente mono- o independientemente polisustituido con halogeno, alcoxi, haloalcoxi, alquilsulfanilo, haloalquilsulfanilo, alquilsulfinilo, haloalquilsulfinilo, alquilsulfonilo, haloalquilsulfonilo, alquilcarbonilo, alcoxicarbonilo y/o cicloalquilo; cicloalquilo que está opcionalmente mono- o independientemente polisustituido con alquilo, haloalquilo y/o halogeno; haloalquilo que está opcionalmente mono- o independientemente polisustituido con alcoxi, alquilsulfanilo, haloalquilsulfanilo, alquilsulfinilo, haloalquilsulfinilo, alquilsulfonilo, haloalquilsulfonilo y/o fenilo, opcionalmente mono- o independientemente polisustituido con halogeno, alquilo, haloalquilo y/o alcoxi; fenilo que está opcionalmente mono- o independientemente polisustituido con halogeno, alquilo, haloalquilo y/o alcoxi; bencilo que está opcionalmente mono- o independientemente polisustituido con halogeno, alquilo, haloalquilo y/o alcoxi; ciano, formilo, alquilcarbonilo, -CH=NO-H, -CH=NO-alquilo, -CH=NO-haloalquilo, -C(CH3)=NO-H, -C(CH3)=NO-alquilo o -C(CH3)=NO-haloalquilo; R2 es amino opcionalmente sustituido, donde el amino puede estar mono- o independientemente disustituido con alquilo, haloalquilo, alcoxialquilo, alquilsulfanilalquilo, alquilsulfinilalquilo, alquilsulfonilalquilo, alquilcarbonilo, cicloalquilo, cicloalquilalquilo, alquenilo, donde los radicales anteriores están opcionalmente sustituidos con halogeno, ciano, alcoxi, alcoxicarbonilo o fenilo, donde el anillo de fenilo está opcionalmente mono- o polisustituido con uno o más sustituyentes seleccionados independientemente entre halogeno, alquilo, haloalquilo y alcoxi; alquinilo, alcoxicarbonilo, alqueniloxicarbonilo, alquiniloxicarbonilo, alcoxicarbonilalquilo, alcoxicarbonilcarbonilo, heterociclilo, heteroarilo, heterociclilalquilo o heteroarilalquilo, donde el anillo heterocíclico o heteroaromático puede estar opcionalmente mono- o polisustituido con uno o más sustituyentes seleccionados independientemente entre halogeno, alquilo, haloalquilo y alcoxi; bencilo o fenilcarbonilo, donde el anillo de fenilo en el bencilo y fenilcarbonilo está opcionalmente mono- o polisustituido con uno o más sustituyentes seleccionados independientemente entre halogeno, alquilo, haloalquilo y alcoxi; y cada uno de R3 y R4 es independientemente hidrogeno, halogeno, alquilo, cicloalquilo, haloalquilo, ciano, hidroxilo, formilo, alquilcarbonilo, -CH=NO-H, -CH=NO-alquilo, -CH=NO-haloalquilo, -C(CH3)=NOH, -C(CH3)=NO-alquilo, -C(CH3)=NO-haloalquilo, nitro, hidroxilo, SH, alcoxi, alquilsulfanilo, haloalquilsulfanilo, alquilsulfinilo, haloalquilsulfinilo, alquilsulfonilo o haloalquilsulfonilo; R5 es halogeno, alquilo, haloalquilo, hidroxilo, alcoxi, alcoxialquilo, alcoxialcoxi, cicloalquilo, alqueniloxi, alquiniloxi, benciloxi, cicloalquilalcoxi, haloalcoxi, haloalcoxialquilo, -SH, alquilsulfanilo, haloalquilsulfanilo, alquilsulfinilo, haloalquilsulfinilo, alquilsulfonilo, haloalquilsulfonilo, ciano, nitro, alquilcarbonilo, alcoxicarbonilo, alcoxicarbonilalquilo, carboxilo, carboxamida, dialquilcarboxamida, trialquilsililo, nitro, amino, alquilamino, dialquilamino, alquilsulfonilamino, dialquilsulfonilamino, formilo, -CH=NO-H, -CH=NO-alquilo, -CH=NO-haloalquilo, -C(CH3)=NO-H, -C(CH3)NO-alquilo, -C(CH3)=NO-haloalquilo o heteroarilo, donde el anillo heteroaromático puede estar opcionalmente mono o polisustituido con uno o más sustituyentes seleccionados independientemente entre halogeno, alquilo, haloalquilo y alcoxi; y los N-oxidos y sales dejos compuestos de formula general (1).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09161568A EP2266973A1 (de) | 2009-05-29 | 2009-05-29 | Pyrazinylpyrazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR076798A1 true AR076798A1 (es) | 2011-07-06 |
Family
ID=40897591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100101827A AR076798A1 (es) | 2009-05-29 | 2010-05-26 | Pirazinilpirazoles y composiciones que comprenden dichos compuestos |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20120190687A1 (es) |
| EP (2) | EP2266973A1 (es) |
| KR (1) | KR101758935B1 (es) |
| CN (1) | CN102459235B (es) |
| AR (1) | AR076798A1 (es) |
| AU (1) | AU2010252346B2 (es) |
| BR (1) | BRPI1012771A2 (es) |
| CA (1) | CA2763498A1 (es) |
| CO (1) | CO6470821A2 (es) |
| DO (1) | DOP2011000366A (es) |
| EC (1) | ECSP11011487A (es) |
| ES (1) | ES2409891T3 (es) |
| IL (1) | IL216337A (es) |
| MX (1) | MX2011012504A (es) |
| NI (1) | NI201100208A (es) |
| NZ (1) | NZ596681A (es) |
| PE (1) | PE20120320A1 (es) |
| TW (1) | TW201107310A (es) |
| UY (1) | UY32659A (es) |
| WO (1) | WO2010136145A1 (es) |
| ZA (1) | ZA201108637B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011045224A1 (de) | 2009-10-12 | 2011-04-21 | Bayer Cropscience Ag | 1- (pyrid-3-yl) -pyrazole und 1- (pyrimid-5-yl) -pyrazole als schädlingsbekämpfungsmittel |
| MX2012003376A (es) * | 2009-10-12 | 2012-06-27 | Bayer Cropscience Ag | Amidas y tioamidas como agentes para combatir parasitos. |
| WO2011057984A1 (de) | 2009-11-11 | 2011-05-19 | Bayer Cropscience Ag | Neue diazinyl-pyrazolylverbindungen |
| WO2012000896A2 (de) | 2010-06-28 | 2012-01-05 | Bayer Cropscience Ag | Heterocyclische verbindungen als schädlingsbekämpfungsmittel |
| DE102010063691A1 (de) * | 2010-12-21 | 2012-06-21 | Bayer Animal Health Gmbh | Ektoparasitizide Wirkstoffkombinationen |
| US9556141B2 (en) | 2011-11-21 | 2017-01-31 | Basf Se | Process for preparing N-substituted 1H-pyrazole-5-carboxylate compounds and derivatives thereof |
| JP2015517455A (ja) | 2012-05-04 | 2015-06-22 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 置換ピラゾール含有化合物、および殺有害生物剤としてのその使用 |
| CN105101800B (zh) * | 2012-10-02 | 2018-04-13 | 拜耳农作物科学股份公司 | 作为杀虫剂的杂环化合物 |
| CN104884449A (zh) * | 2012-10-31 | 2015-09-02 | 拜尔农作物科学股份公司 | 作为害虫防治剂的新的杂环化合物 |
| WO2016174049A1 (en) | 2015-04-30 | 2016-11-03 | Bayer Animal Health Gmbh | Anti-parasitic combinations including halogen-substituted compounds |
| JP6569184B2 (ja) | 2015-06-18 | 2019-09-04 | 日本曹達株式会社 | ジアリールアゾール化合物および有害生物防除剤 |
| CN108368064B (zh) | 2015-11-30 | 2022-04-26 | 北兴化学工业株式会社 | 1,2,3-三唑衍生物和包含这种衍生物作为活性成分的杀虫剂和杀螨剂 |
| JP6779908B2 (ja) | 2015-12-16 | 2020-11-04 | 日本曹達株式会社 | アリールアゾール化合物および有害生物防除剤 |
| US11078181B2 (en) | 2016-12-19 | 2021-08-03 | Nippon Soda Co., Ltd. | Diaryl pyrazole compound and formulation for controlling harmful organisms |
| CN110305115A (zh) * | 2019-08-19 | 2019-10-08 | 南通大学 | 一种含1-(6-氯吡嗪-2-基)-3-甲氧基吡唑单元的吡唑肟衍生物的制备和应用 |
| WO2021219527A1 (de) * | 2020-04-29 | 2021-11-04 | Bayer Aktiengesellschaft | 1-pyrazinylpyrazolyl-3-oxyalkylsäuren sowie deren derivate und deren verwendung zur bekämpfung unerwünschten pflanzenwachstums |
| WO2024121263A1 (en) | 2022-12-09 | 2024-06-13 | Syngenta Crop Protection Ag | Insecticidal compound based on pyrazole derivatives |
| WO2024121262A1 (en) | 2022-12-09 | 2024-06-13 | Syngenta Crop Protection Ag | Insecticidal compound based on pyrazole derivatives |
| WO2024121264A1 (en) | 2022-12-09 | 2024-06-13 | Syngenta Crop Protection Ag | Insecticidal compound based on pyrazole derivatives |
| WO2024121261A1 (en) | 2022-12-09 | 2024-06-13 | Syngenta Crop Protection Ag | Insecticidal compound based on pyrazole derivatives |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU38903A1 (es) | 1959-07-03 | |||
| FR2326421A1 (fr) | 1975-09-30 | 1977-04-29 | Ugine Kuhlmann | Nouveaux trifluoromethyl-3-aryl-4 amino-5 pyrazoles et leur application comme bases diazotables pour la synthese de matieres colorantes |
| US4101540A (en) | 1975-09-30 | 1978-07-18 | Produits Chimiques Ugine Kuhlmann | 3-Trifluoromethyl-4-phenyl-pyrazolium azo dyestuffs |
| JPH08208620A (ja) | 1995-02-03 | 1996-08-13 | Takeda Chem Ind Ltd | アミノピラゾール誘導体、その製造法および用途 |
| DE19544799A1 (de) * | 1995-12-01 | 1997-06-05 | Bayer Ag | Substituierte 5-Aminopyrazole |
| CA2278677A1 (en) | 1997-01-27 | 1998-07-30 | Daiichi Pharmaceutical Co., Ltd. | Pyrazole derivatives |
| US6169086B1 (en) | 1997-01-27 | 2001-01-02 | Daiichi Pharmaceutical Co., Ltd. | Pyrazole derivatives |
| NZ502612A (en) | 1998-06-10 | 2001-06-29 | Boulder Scient Co | Synthesis of aryl boronic acids |
| US6518266B1 (en) * | 1999-07-22 | 2003-02-11 | 3-Dimensional Pharmaceuticals | 1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides |
| US7514464B2 (en) | 2003-12-18 | 2009-04-07 | Pfizer Limited | Substituted arylpyrazoles |
| JP2009506127A (ja) | 2005-08-31 | 2009-02-12 | バイエル・ヘルスケア・エルエルシー | 糖尿病の処置に有用なアニリノピラゾール誘導体 |
| WO2007048733A1 (de) | 2005-10-28 | 2007-05-03 | Basf Se | Verwendung von 5-amino-pyrazolen zur bekämpfung pflanzenpathogener schadpilze, neue 5-amino-pyrazole, verfahren zu ihrer herstellung und sie enthaltende mittel |
| DE102007003036A1 (de) | 2006-12-20 | 2008-06-26 | Bayer Cropscience Ag | Pyrimidinylpyrazole |
| WO2009156090A2 (de) * | 2008-06-26 | 2009-12-30 | Bayer Cropscience Aktiengesellschaft | Insektizide schwefel-derivatisierte 1-azinylpyrazole |
| WO2011057984A1 (de) * | 2009-11-11 | 2011-05-19 | Bayer Cropscience Ag | Neue diazinyl-pyrazolylverbindungen |
-
2009
- 2009-05-29 EP EP09161568A patent/EP2266973A1/de not_active Withdrawn
-
2010
- 2010-05-19 CA CA2763498A patent/CA2763498A1/en not_active Abandoned
- 2010-05-19 KR KR1020117031386A patent/KR101758935B1/ko active IP Right Grant
- 2010-05-19 CN CN201080033587.6A patent/CN102459235B/zh not_active Expired - Fee Related
- 2010-05-19 EP EP10721330A patent/EP2435420B1/de not_active Not-in-force
- 2010-05-19 WO PCT/EP2010/003060 patent/WO2010136145A1/de active Application Filing
- 2010-05-19 AU AU2010252346A patent/AU2010252346B2/en not_active Ceased
- 2010-05-19 MX MX2011012504A patent/MX2011012504A/es active IP Right Grant
- 2010-05-19 NZ NZ596681A patent/NZ596681A/en not_active IP Right Cessation
- 2010-05-19 ES ES10721330T patent/ES2409891T3/es active Active
- 2010-05-19 BR BRPI1012771A patent/BRPI1012771A2/pt not_active Application Discontinuation
- 2010-05-19 PE PE2011002013A patent/PE20120320A1/es not_active Application Discontinuation
- 2010-05-19 US US13/375,164 patent/US20120190687A1/en not_active Abandoned
- 2010-05-25 UY UY0001032659A patent/UY32659A/es not_active Application Discontinuation
- 2010-05-26 AR ARP100101827A patent/AR076798A1/es unknown
- 2010-05-28 TW TW099117101A patent/TW201107310A/zh unknown
- 2010-05-28 US US12/801,253 patent/US8513260B2/en not_active Expired - Fee Related
-
2011
- 2011-11-14 IL IL216337A patent/IL216337A/en not_active IP Right Cessation
- 2011-11-24 ZA ZA2011/08637A patent/ZA201108637B/en unknown
- 2011-11-24 CO CO11161605A patent/CO6470821A2/es not_active Application Discontinuation
- 2011-11-25 DO DO2011000366A patent/DOP2011000366A/es unknown
- 2011-11-28 EC EC2011011487A patent/ECSP11011487A/es unknown
- 2011-11-28 NI NI201100208A patent/NI201100208A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2266973A1 (de) | 2010-12-29 |
| CN102459235B (zh) | 2015-03-11 |
| NI201100208A (es) | 2012-08-17 |
| ECSP11011487A (es) | 2011-12-30 |
| IL216337A0 (en) | 2012-01-31 |
| US8513260B2 (en) | 2013-08-20 |
| CA2763498A1 (en) | 2010-12-02 |
| CO6470821A2 (es) | 2012-06-29 |
| KR20120061779A (ko) | 2012-06-13 |
| MX2011012504A (es) | 2011-12-12 |
| CN102459235A (zh) | 2012-05-16 |
| NZ596681A (en) | 2015-09-25 |
| EP2435420A1 (de) | 2012-04-04 |
| US20120190687A1 (en) | 2012-07-26 |
| PE20120320A1 (es) | 2012-03-30 |
| IL216337A (en) | 2015-09-24 |
| KR101758935B1 (ko) | 2017-07-17 |
| AU2010252346B2 (en) | 2015-11-19 |
| WO2010136145A1 (de) | 2010-12-02 |
| ES2409891T3 (es) | 2013-06-28 |
| ZA201108637B (en) | 2013-01-30 |
| AU2010252346A1 (en) | 2011-12-22 |
| EP2435420B1 (de) | 2013-04-03 |
| UY32659A (es) | 2010-12-31 |
| BRPI1012771A2 (pt) | 2016-03-29 |
| DOP2011000366A (es) | 2011-12-15 |
| US20110021539A1 (en) | 2011-01-27 |
| TW201107310A (en) | 2011-03-01 |
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