US3687808A
(en)
|
1969-08-14 |
1972-08-29 |
Univ Leland Stanford Junior |
Synthetic polynucleotides
|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
US4109496A
(en)
|
1977-12-20 |
1978-08-29 |
Norris Industries |
Trapped key mechanism
|
US4323546A
(en)
|
1978-05-22 |
1982-04-06 |
Nuc Med Inc. |
Method and composition for cancer detection in humans
|
US4411990A
(en)
|
1979-06-13 |
1983-10-25 |
University Patents, Inc. |
Primary bioassay of human tumor stem cells
|
US4873191A
(en)
|
1981-06-12 |
1989-10-10 |
Ohio University |
Genetic transformation of zygotes
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
US4612282A
(en)
|
1981-12-15 |
1986-09-16 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Monoclonal antibodies reactive with human breast cancer
|
US4670393A
(en)
|
1982-03-22 |
1987-06-02 |
Genentech, Inc. |
DNA vectors encoding a novel human growth hormone-variant protein
|
US4588585A
(en)
|
1982-10-19 |
1986-05-13 |
Cetus Corporation |
Human recombinant cysteine depleted interferon-β muteins
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
EP0154316B1
(en)
|
1984-03-06 |
1989-09-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified lymphokine and production thereof
|
US5019497A
(en)
|
1984-11-09 |
1991-05-28 |
Lennart Olsson |
Human squamous lung carcinoma cell specific antigens and antibodies
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
US5080891A
(en)
|
1987-08-03 |
1992-01-14 |
Ddi Pharmaceuticals, Inc. |
Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
|
US5087570A
(en)
|
1988-05-10 |
1992-02-11 |
Weissman Irving L |
Homogeneous mammalian hematopoietic stem cell composition
|
US4981785A
(en)
|
1988-06-06 |
1991-01-01 |
Ventrex Laboratories, Inc. |
Apparatus and method for performing immunoassays
|
US4968103A
(en)
|
1988-07-22 |
1990-11-06 |
Photofinish Cosmetics Inc. |
Method of making a brush
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
US5994617A
(en)
|
1988-09-19 |
1999-11-30 |
Hsc Research Development Corporation |
Engraftment of immune-deficient mice with human cells
|
US5688666A
(en)
|
1988-10-28 |
1997-11-18 |
Genentech, Inc. |
Growth hormone variants with altered binding properties
|
US5534617A
(en)
|
1988-10-28 |
1996-07-09 |
Genentech, Inc. |
Human growth hormone variants having greater affinity for human growth hormone receptor at site 1
|
JP2989002B2
(ja)
|
1988-12-22 |
1999-12-13 |
キリン―アムジエン・インコーポレーテツド |
化学修飾顆粒球コロニー刺激因子
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
GB8901778D0
(en)
|
1989-01-27 |
1989-03-15 |
Univ Court Of The University O |
Manipulatory technique
|
US6583115B1
(en)
|
1989-10-12 |
2003-06-24 |
Ohio University/Edison Biotechnology Institute |
Methods for treating acromegaly and giantism with growth hormone antagonists
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
US5061620A
(en)
|
1990-03-30 |
1991-10-29 |
Systemix, Inc. |
Human hematopoietic stem cell
|
US5270163A
(en)
|
1990-06-11 |
1993-12-14 |
University Research Corporation |
Methods for identifying nucleic acid ligands
|
US5705337A
(en)
|
1990-06-11 |
1998-01-06 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-SELEX
|
US5683867A
(en)
|
1990-06-11 |
1997-11-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: blended SELEX
|
US5496938A
(en)
|
1990-06-11 |
1996-03-05 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands to HIV-RT and HIV-1 rev
|
US6344321B1
(en)
|
1990-06-11 |
2002-02-05 |
Gilead Sciences, Inc. |
Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
|
US5614396A
(en)
|
1990-06-14 |
1997-03-25 |
Baylor College Of Medicine |
Methods for the genetic modification of endogenous genes in animal cells by homologous recombination
|
US5489677A
(en)
|
1990-07-27 |
1996-02-06 |
Isis Pharmaceuticals, Inc. |
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
ATE164395T1
(de)
|
1990-12-03 |
1998-04-15 |
Genentech Inc |
Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
|
US5840867A
(en)
|
1991-02-21 |
1998-11-24 |
Gilead Sciences, Inc. |
Aptamer analogs specific for biomolecules
|
US5856441A
(en)
|
1991-05-03 |
1999-01-05 |
Yale University |
Serrate fragments and derivatives
|
IL101728A
(en)
|
1991-05-03 |
2007-08-19 |
Univ Yale |
Human Abandonment and Delta, Restrictive Areas of Effect in Tophoric Proteins, and Methods Based on Them
|
IE20030749A1
(en)
|
1991-05-03 |
2003-11-12 |
Indiana University Foundation |
Human notch and delta binding domains in torporythmic proteins, and methods based thereon
|
US6429186B1
(en)
|
1991-05-10 |
2002-08-06 |
Genentech, Inc. |
Ligand antagonists for treatment of breast cancer
|
US5539082A
(en)
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
US5714331A
(en)
|
1991-05-24 |
1998-02-03 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
US5750376A
(en)
|
1991-07-08 |
1998-05-12 |
Neurospheres Holdings Ltd. |
In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
|
US5582981A
(en)
|
1991-08-14 |
1996-12-10 |
Gilead Sciences, Inc. |
Method for identifying an oligonucleotide aptamer specific for a target
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
US5753229A
(en)
|
1991-09-25 |
1998-05-19 |
Mordoh; Jose |
Monoclonal antibodies reactive with tumor proliferating cells
|
US6353150B1
(en)
|
1991-11-22 |
2002-03-05 |
Hsc Research And Development Limited Partnership |
Chimeric mammals with human hematopoietic cells
|
US6004924A
(en)
|
1991-12-11 |
1999-12-21 |
Imperial Cancer Research Technology, Ltd. |
Protein sequences of serrate gene products
|
US5869282A
(en)
|
1991-12-11 |
1999-02-09 |
Imperial Cancer Research Technology, Ltd. |
Nucleotide and protein sequences of the serrate gene and methods based thereon
|
DE69326967T2
(de)
|
1992-01-17 |
2000-06-15 |
Lakowicz Joseph R |
Phasenmodulationsenergieübertragungsfluoroimmunassay
|
US5376313A
(en)
|
1992-03-27 |
1994-12-27 |
Abbott Laboratories |
Injection molding a plastic assay cuvette having low birefringence
|
US5786158A
(en)
|
1992-04-30 |
1998-07-28 |
Yale University |
Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
|
US5928947A
(en)
|
1992-07-27 |
1999-07-27 |
California Institute Of Technology |
Mammalian multipotent neural stem cells
|
AU678988B2
(en)
|
1992-07-27 |
1997-06-19 |
California Institute Of Technology |
Mammalian multipotent neural stem cells
|
US5654183A
(en)
|
1992-07-27 |
1997-08-05 |
California Institute Of Technology |
Genetically engineered mammalian neural crest stem cells
|
US5849553A
(en)
|
1992-07-27 |
1998-12-15 |
California Institute Of Technology |
Mammalian multipotent neural stem cells
|
US5589376A
(en)
|
1992-07-27 |
1996-12-31 |
California Institute Of Technology |
Mammalian neural crest stem cells
|
US5756291A
(en)
|
1992-08-21 |
1998-05-26 |
Gilead Sciences, Inc. |
Aptamers specific for biomolecules and methods of making
|
ATE316573T1
(de)
|
1992-10-30 |
2006-02-15 |
Gen Hospital Corp |
Wechselwirkendes fallensystem zur isolierung von proteinen
|
GB9223084D0
(en)
|
1992-11-04 |
1992-12-16 |
Imp Cancer Res Tech |
Compounds to target cells
|
JP3106021B2
(ja)
|
1992-11-30 |
2000-11-06 |
キヤノン株式会社 |
パターンデータの圧縮方法及び装置と出力方法及び装置
|
KR100283601B1
(ko)
|
1993-02-19 |
2001-03-02 |
아만 히데아키 |
글리세롤 유도체, 디바이스 및 의약 조성물
|
US5643765A
(en)
|
1993-04-06 |
1997-07-01 |
University Of Rochester |
Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
|
US5876978A
(en)
|
1993-04-06 |
1999-03-02 |
Medical College Of Ohio |
Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
|
US5639606A
(en)
|
1993-04-06 |
1997-06-17 |
The University Of Rochester |
Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
|
US5538848A
(en)
|
1994-11-16 |
1996-07-23 |
Applied Biosystems Division, Perkin-Elmer Corp. |
Method for detecting nucleic acid amplification using self-quenching fluorescence probe
|
US5599677A
(en)
|
1993-12-29 |
1997-02-04 |
Abbott Laboratories |
Immunoassays for prostate specific antigen
|
DE69535178T2
(de)
|
1994-06-10 |
2006-12-14 |
Genvec, Inc. |
Adenoviren-vektor systeme und zelllinien
|
US6156305A
(en)
|
1994-07-08 |
2000-12-05 |
Baxter International Inc. |
Implanted tumor cells for the prevention and treatment of cancer
|
US5650317A
(en)
|
1994-09-16 |
1997-07-22 |
Michigan State University |
Human breast epithelial cell type with stem cell and luminal epithelial cell characteristics
|
DE69534166T2
(de)
|
1994-10-28 |
2006-03-09 |
Trustees Of The University Of Pennsylvania |
Rekombinanter adenovirus und methoden zu dessen verwendung
|
US6218166B1
(en)
|
1994-12-09 |
2001-04-17 |
John Wayne Cancer Institute |
Adjuvant incorporation into antigen carrying cells: compositions and methods
|
US5736396A
(en)
|
1995-01-24 |
1998-04-07 |
Case Western Reserve University |
Lineage-directed induction of human mesenchymal stem cell differentiation
|
US5872154A
(en)
|
1995-02-24 |
1999-02-16 |
The Trustees Of The University Of Pennsylvania |
Method of reducing an immune response to a recombinant adenovirus
|
US6207147B1
(en)
|
1996-10-11 |
2001-03-27 |
The Regents Of The University Of California |
Cancer immunotherapy using tumor cells combined with mixed lymphocytes
|
US5707618A
(en)
|
1995-03-24 |
1998-01-13 |
Genzyme Corporation |
Adenovirus vectors for gene therapy
|
US5633161A
(en)
|
1995-03-29 |
1997-05-27 |
Millennium Pharmaceuticals, Inc. |
Murine gene fomy030 coding for tumor progression inhibitor
|
US5821108A
(en)
|
1995-04-07 |
1998-10-13 |
The Board Of Trustees Of The Leland Stanford Junior University |
Enrichment for a thymocyte subset having progenitor cell activity using c-kit as a selection marker
|
US5739277A
(en)
|
1995-04-14 |
1998-04-14 |
Genentech Inc. |
Altered polypeptides with increased half-life
|
AU6261696A
(en)
|
1995-06-05 |
1996-12-24 |
Trustees Of The University Of Pennsylvania, The |
A replication-defective adenovirus human type 5 recombinant as a vaccine carrier
|
DK1445322T4
(da)
|
1995-06-15 |
2012-09-03 |
Crucell Holland Bv |
Pakningssystemer for humant rekombinant adenovirus til anvendelse ved genterapi
|
US6117985A
(en)
|
1995-06-16 |
2000-09-12 |
Stemcell Technologies Inc. |
Antibody compositions for preparing enriched cell preparations
|
DK0861261T3
(da)
|
1995-06-28 |
2009-12-14 |
Imp Cancer Res Tech |
Nukleotid- og proteinsekvenser af hvirveldyrs-Delta-gener og fremgangsmåder baseret derpå
|
DE69638117D1
(de)
|
1995-09-21 |
2010-03-04 |
Genentech Inc |
Varianten des menschlichen Wachstumshormons
|
US5780300A
(en)
|
1995-09-29 |
1998-07-14 |
Yale University |
Manipulation of non-terminally differentiated cells using the notch pathway
|
US5986170A
(en)
|
1995-11-13 |
1999-11-16 |
Corixa Corporation |
Murine model for human carcinoma
|
AU716889B2
(en)
|
1995-11-17 |
2000-03-09 |
Asahi Kasei Kogyo Kabushiki Kaisha |
Differentiation-suppressive polypeptide
|
EP0874993A1
(en)
|
1995-12-22 |
1998-11-04 |
Abbott Laboratories |
Fluorescence polarization immunoassay diagnostic method
|
US5994316A
(en)
|
1996-02-21 |
1999-11-30 |
The Immune Response Corporation |
Method of preparing polynucleotide-carrier complexes for delivery to cells
|
ES2177964T3
(es)
|
1996-03-30 |
2002-12-16 |
Science Park Raf S P A |
Procedimiento de produccion de celulas t activadas marcadas especificas de tumores y su uso para el tratamiento de tumores.
|
US5753506A
(en)
|
1996-05-23 |
1998-05-19 |
Cns Stem Cell Technology, Inc. |
Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
|
US6716974B1
(en)
|
1996-05-31 |
2004-04-06 |
Maine Medical Center Research Institute |
Therapeutic and diagnostic methods and compositions based on jagged/notch proteins and nucleic acids
|
JP2000512134A
(ja)
|
1996-05-31 |
2000-09-19 |
ザ ナショナル アメリカン レッド クロス |
Jagged/Notchタンパク質および核酸に基づく治療および診断の方法および組成物
|
US5885529A
(en)
|
1996-06-28 |
1999-03-23 |
Dpc Cirrus, Inc. |
Automated immunoassay analyzer
|
FR2751986B1
(fr)
|
1996-08-01 |
1998-12-31 |
Inst Nat Sante Rech Med |
Gene implique dans le cadasil, methode de diagnostic et application therapeutique
|
AU723836B2
(en)
|
1996-08-29 |
2000-09-07 |
Regents Of The University Of California, The |
Kuz, a novel family of metalloproteases
|
DK0932678T4
(da)
|
1996-09-24 |
2010-07-12 |
Genentech Inc |
En familie af gener kodende for apoptoserelaterede peptider, peptider kodet deraf og fremgangsmåder til anvendelse deraf
|
US5994132A
(en)
|
1996-10-23 |
1999-11-30 |
University Of Michigan |
Adenovirus vectors
|
ATE425990T1
(de)
|
1996-11-27 |
2009-04-15 |
Genentech Inc |
Affinitatsreinigung von polypeptid-proteinen auf einer matrix
|
US5859535A
(en)
|
1997-02-12 |
1999-01-12 |
The United States Of America As Represented By The Secretary Of The Navy |
System for determining size and location of defects in material by use of microwave radiation
|
CA2283267A1
(en)
|
1997-03-07 |
1998-09-11 |
Clare Chemical Research Llc |
Fluorometric detection using visible light
|
US6080912A
(en)
|
1997-03-20 |
2000-06-27 |
Wisconsin Alumni Research Foundation |
Methods for creating transgenic animals
|
US5861832A
(en)
|
1997-03-27 |
1999-01-19 |
Lucent Technologies Inc. |
Analog-to-digital converter having amplifier and comparator stages
|
US20020137890A1
(en)
|
1997-03-31 |
2002-09-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US6121045A
(en)
|
1997-04-04 |
2000-09-19 |
Millennium Biotherapeutics, Inc. |
Human Delta3 nucleic acid molecules
|
ES2275304T3
(es)
|
1997-04-04 |
2007-06-01 |
Millennium Pharmaceuticals, Inc. |
Nuevas composiciones de delta-3 humana y usos diagnosticos y terapeuticos para las mismas.
|
US20030180784A1
(en)
|
1997-04-04 |
2003-09-25 |
Millennium Pharmaceuticals, Inc. |
Novel human Delta3 compositions and therapeutic and diagnostic uses therefor
|
US5830730A
(en)
|
1997-05-08 |
1998-11-03 |
The Regents Of The University Of California |
Enhanced adenovirus-assisted transfection composition and method
|
AU730782B2
(en)
|
1997-05-14 |
2001-03-15 |
Asahi Kasei Kabushiki Kaisha |
Novel differentiation-inhibitor
|
AU7704498A
(en)
|
1997-05-29 |
1998-12-30 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Human frp and fragments thereof including methods for using them
|
WO1998057621A1
(en)
|
1997-06-18 |
1998-12-23 |
The Trustees Of Columbia University In The City Ofnew York |
Angiogenic modulation by notch signal transduction
|
US6379925B1
(en)
|
1997-06-18 |
2002-04-30 |
The Trustees Of Columbia University In The City Of New York |
Angiogenic modulation by notch signal transduction
|
US6136952A
(en)
|
1997-06-25 |
2000-10-24 |
University Of Washington |
Human jagged polypeptide, encoding nucleic acids and methods of use
|
WO1999002685A1
(en)
|
1997-07-11 |
1999-01-21 |
Introgene B.V. |
Interleukin-3 gene therapy for cancer
|
US6004528A
(en)
|
1997-09-18 |
1999-12-21 |
Bergstein; Ivan |
Methods of cancer diagnosis and therapy targeted against the cancer stemline
|
US7361336B1
(en)
|
1997-09-18 |
2008-04-22 |
Ivan Bergstein |
Methods of cancer therapy targeted against a cancer stem line
|
US6197523B1
(en)
|
1997-11-24 |
2001-03-06 |
Robert A. Levine |
Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood
|
US6506559B1
(en)
|
1997-12-23 |
2003-01-14 |
Carnegie Institute Of Washington |
Genetic inhibition by double-stranded RNA
|
US6551795B1
(en)
|
1998-02-18 |
2003-04-22 |
Genome Therapeutics Corporation |
Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
|
US5981225A
(en)
|
1998-04-16 |
1999-11-09 |
Baylor College Of Medicine |
Gene transfer vector, recombinant adenovirus particles containing the same, method for producing the same and method of use of the same
|
US6252050B1
(en)
|
1998-06-12 |
2001-06-26 |
Genentech, Inc. |
Method for making monoclonal antibodies and cross-reactive antibodies obtainable by the method
|
JP2002523018A
(ja)
|
1998-07-27 |
2002-07-30 |
アムジエン・インコーポレーテツド |
デルタ関連ポリペプチド
|
EP1109896A4
(en)
|
1998-08-14 |
2005-11-02 |
Aventis Pharm Prod Inc |
ADENOVIRUS FORMULATIONS FOR GENE THERAPY
|
CA2341061A1
(en)
|
1998-08-27 |
2000-03-09 |
Aventis Pharma S.A. |
Targeted adenovirus vectors for delivery of heterologous genes
|
GB9819681D0
(en)
|
1998-09-09 |
1998-11-04 |
Smithkline Beecham Plc |
Novel compounds
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
JP4574012B2
(ja)
|
1998-11-02 |
2010-11-04 |
キュリス,インコーポレイテッド |
ヘッジホッグ活性の機能的アンタゴニスト
|
US6291516B1
(en)
|
1999-01-13 |
2001-09-18 |
Curis, Inc. |
Regulators of the hedgehog pathway, compositions and uses related thereto
|
US20030054360A1
(en)
|
1999-01-19 |
2003-03-20 |
Larry Gold |
Method and apparatus for the automated generation of nucleic acid ligands
|
US20030003572A1
(en)
|
1999-03-05 |
2003-01-02 |
David J. Anderson |
Isolation and enrichment of neural stem cells from uncultured tissue based on cell-surface marker expression
|
US20030119029A1
(en)
|
1999-04-30 |
2003-06-26 |
Regents Of The University Of Michigan |
Compositions and methods relating to novel benzodiazepine compounds and targets thereof
|
IL146842A0
(en)
|
1999-06-01 |
2002-07-25 |
Biogen Inc |
Polymer conjugates of hedgehog proteins and uses
|
WO2001002568A2
(en)
|
1999-07-02 |
2001-01-11 |
Chiron Corporation |
Human genes and gene expression products
|
US6703221B1
(en)
|
1999-08-19 |
2004-03-09 |
Chiron Corporation |
Notch receptor ligands and uses thereof
|
EP1265582A2
(en)
|
1999-09-29 |
2002-12-18 |
Human Genome Sciences, Inc. |
Colon and colon cancer associated polynucleotides and polypeptides
|
AU1194501A
(en)
|
1999-10-14 |
2001-04-23 |
Wistar Institute, The |
Inhibition of tumorigenic properties of melanoma cells
|
US6380362B1
(en)
|
1999-12-23 |
2002-04-30 |
Genesis Research & Development Corporation Ltd. |
Polynucleotides, polypeptides expressed by the polynucleotides and methods for their use
|
US20040048249A1
(en)
|
2000-01-21 |
2004-03-11 |
Tang Y. Tom |
Novel nucleic acids and secreted polypeptides
|
CA2397543A1
(en)
|
2000-01-24 |
2001-07-26 |
Timothy Harrison |
Gamma-secretase inhibitors
|
AU4314801A
(en)
|
2000-02-11 |
2001-08-20 |
Lexigen Pharm Corp |
Enhancing the circulating half-life of antibody-based fusion proteins
|
US7115653B2
(en)
|
2000-03-30 |
2006-10-03 |
Curis, Inc. |
Small organic molecule regulators of cell proliferation
|
WO2001098537A2
(en)
|
2000-06-17 |
2001-12-27 |
Third Wave Technologies, Inc. |
Nucleic acid accessible hybridization sites
|
WO2001098354A2
(en)
|
2000-06-21 |
2001-12-27 |
Incyte Genomics, Inc. |
Human receptors
|
US6632620B1
(en)
|
2000-06-22 |
2003-10-14 |
Andrew N. Makarovskiy |
Compositions for identification and isolation of stem cells
|
DE10031380A1
(de)
|
2000-06-28 |
2002-01-10 |
Merck Patent Gmbh |
Verfahren zur Übertragung von Alkyliden-Gruppen auf organischen Verbindungen
|
GB0016681D0
(en)
|
2000-07-06 |
2000-08-23 |
Merck Sharp & Dohme |
Therapeutic compounds
|
US7118853B2
(en)
|
2000-07-26 |
2006-10-10 |
Applied Genomics, Inc. |
Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors
|
US8044259B2
(en)
|
2000-08-03 |
2011-10-25 |
The Regents Of The University Of Michigan |
Determining the capability of a test compound to affect solid tumor stem cells
|
US6984522B2
(en)
|
2000-08-03 |
2006-01-10 |
Regents Of The University Of Michigan |
Isolation and use of solid tumor stem cells
|
AU2001288628A1
(en)
|
2000-08-31 |
2002-03-13 |
Loyola University Chicago |
Method and reagents for treatment of skin disorders by modulating the notch pathway
|
US6689744B2
(en)
|
2000-09-22 |
2004-02-10 |
Genentech, Inc. |
Notch receptor agonists and uses
|
EP2322648A1
(en)
|
2000-09-26 |
2011-05-18 |
Duke University |
RNA aptamers and methods for identifying the same
|
WO2002060919A2
(en)
|
2000-12-12 |
2002-08-08 |
Medimmune, Inc. |
Molecules with extended half-lives, compositions and uses thereof
|
EP2105503B1
(en)
|
2000-12-13 |
2012-09-19 |
Anaphore, Inc. |
Method for the identification and isolation of binding polypeptides from combinatorial libraries of proteins having the scaffold structure of C-type lectin-like domains
|
US7413873B2
(en)
|
2001-01-30 |
2008-08-19 |
The Regents Of The University Of California |
Method of detection and treatment of colon cancer
|
US20020169300A1
(en)
|
2001-01-30 |
2002-11-14 |
Waterman Marian L. |
Method of detection and treatment of colon cancer by analysis of beta-catenin-sensitive isoforms of lymphoid enhancer factor-1
|
US20030064384A1
(en)
|
2001-04-02 |
2003-04-03 |
Mien-Chie Hung |
Beta-catenin is a strong and independent prognostic factor for cancer
|
IL142481A0
(en)
|
2001-04-05 |
2002-03-10 |
Yissum Res Dev Co |
A method for identifying consitutively active mutants of mitogen activated protein kinases (mapk) and uses thereof
|
US7091323B2
(en)
|
2001-04-24 |
2006-08-15 |
Bayer Corporation |
Human TIMP-1 antibodies
|
AU2002308557A1
(en)
|
2001-05-01 |
2002-11-11 |
The Regents Of The University Of California |
Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas
|
US7713526B2
(en)
|
2001-05-01 |
2010-05-11 |
The Regents Of The University Of California |
Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas
|
US20030044409A1
(en)
|
2001-05-01 |
2003-03-06 |
Carson Dennis A. |
Immunologic compositions and methods for studying and treating cancers expressing frizzled antigens
|
US7514594B2
(en)
|
2001-05-11 |
2009-04-07 |
Wyeth |
Transgenic animal model of bone mass modulation
|
EP1401431A4
(en)
|
2001-06-15 |
2004-07-07 |
Genentech Inc |
HUMAN GROWTH HORMONE ANTAGONISTS
|
US7171311B2
(en)
|
2001-06-18 |
2007-01-30 |
Rosetta Inpharmatics Llc |
Methods of assigning treatment to breast cancer patients
|
US20040023244A1
(en)
|
2001-06-21 |
2004-02-05 |
Griffin Jennifer A |
Receptors
|
US7211404B2
(en)
|
2001-06-22 |
2007-05-01 |
Stem Cells, Inc. |
Liver engrafting cells, assays, and uses thereof
|
WO2003000893A2
(en)
|
2001-06-26 |
2003-01-03 |
Decode Genetics Ehf. |
Nucleic acids encoding g protein-coupled receptors
|
EP1401438B1
(en)
|
2001-07-02 |
2005-09-28 |
Tas, Sinan |
Use of cyclopamine in the treatment of basal cell carcinoma and other tumors
|
CA2452152A1
(en)
|
2001-07-02 |
2002-10-10 |
Sinan Tas |
Use of cyclopamine in the treatment of psoriasis
|
WO2003004045A2
(en)
|
2001-07-05 |
2003-01-16 |
Xenon Genetics, Inc. |
Methods for identifying therapeutic agents for treating diseases involving wnt polypeptides and wnt receptors
|
CA2453810A1
(en)
|
2001-07-18 |
2003-07-03 |
American Red Cross |
Mutant proteinase inhibitors and uses thereof
|
PL372212A1
(en)
|
2001-08-03 |
2005-07-11 |
Schering Corporation |
Novel gamma secretase inhibitors
|
WO2003014960A2
(en)
|
2001-08-03 |
2003-02-20 |
Medical Research Council |
Method of identifying a consensus sequence for intracellular antibodies
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
EP1448599A2
(en)
|
2001-11-14 |
2004-08-25 |
Lorantis Limited |
Inhibitors of the notch signalling pathway for use in the treatment of cancer
|
US7053547B2
(en)
|
2001-11-29 |
2006-05-30 |
Universal Display Corporation |
Increased emission efficiency in organic light-emitting devices on high-index substrates
|
US20070237770A1
(en)
|
2001-11-30 |
2007-10-11 |
Albert Lai |
Novel compositions and methods in cancer
|
AU2002364537A1
(en)
|
2001-12-07 |
2003-06-23 |
Regents Of The University Of Michigan |
Prospective identification and characterization of breast cancer stem cells
|
PL372144A1
(en)
|
2001-12-26 |
2005-07-11 |
Immunomedics, Inc. |
Methods of generating multispecific, multivalent agents from v sb h /sb and v sb l /sb domains
|
US6713206B2
(en)
|
2002-01-14 |
2004-03-30 |
Board Of Trustees Of University Of Illinois |
Electrochemical cells comprising laminar flow induced dynamic conducting interfaces, electronic devices comprising such cells, and methods employing same
|
GB0201674D0
(en)
|
2002-01-25 |
2002-03-13 |
Lorantis Ltd |
Medical treatment
|
EP1481090A4
(en)
|
2002-02-15 |
2006-08-09 |
Somalogic Inc |
METHOD AND REAGENTS FOR DETECTING BINDING OF TARGET MOLECULES BY NUCLEIC ACID ELECTRODES
|
US20030185829A1
(en)
|
2002-03-12 |
2003-10-02 |
Erich Koller |
Jagged 2 inhibitors for inducing apoptosis
|
CA2492671C
(en)
|
2002-03-22 |
2012-04-17 |
Aprogen, Inc. |
Humanized antibody and process for preparing same
|
US7803913B2
(en)
|
2002-05-06 |
2010-09-28 |
The United States Of America As Represented By The Department Of Health And Human Services |
Identification of novel broadly cross-reactive neutralizing human monoclonal antibodies using sequential antigen panning of phage display libraries
|
US20040014111A1
(en)
|
2002-05-24 |
2004-01-22 |
Jun Li |
Methods for the identification of IKKalpha function and other genes useful for treatment of imflammatory diseases
|
WO2004001004A2
(en)
|
2002-06-21 |
2003-12-31 |
Johns Hopkins University School Of Medicine |
Membrane associated tumor endothelium markers
|
WO2004020668A2
(en)
|
2002-08-30 |
2004-03-11 |
Oncotherapy Science, Inc. |
Method for treating synovial sarcoma
|
US7803370B2
(en)
|
2002-08-30 |
2010-09-28 |
Oncotherapy Science, Inc. |
Method for treating synovial sarcoma
|
US20040058217A1
(en)
|
2002-09-20 |
2004-03-25 |
Ohlsen Leroy J. |
Fuel cell systems having internal multistream laminar flow
|
GB0221952D0
(en)
|
2002-09-20 |
2002-10-30 |
Novartis Forschungsstiftung |
Wnt mediated ErbB1 signalling,compositions and uses related thereto
|
US20040247593A1
(en)
|
2002-10-04 |
2004-12-09 |
Regents Of The University Of California, |
Methods for treating cancer by inhibiting Wnt signaling
|
US7365168B2
(en)
|
2002-10-15 |
2008-04-29 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
US20050124565A1
(en)
|
2002-11-21 |
2005-06-09 |
Diener John L. |
Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
|
US7803783B2
(en)
|
2002-12-06 |
2010-09-28 |
The Board Of Trustees Of The Leland Stanford Junior University |
Use of WNT inhibitors to augment therapeutic index of chemotherapy
|
CA2507581A1
(en)
|
2002-12-06 |
2004-06-24 |
The Board Of Trustees Of The Leland Stanford Junior University |
Protection of stem cells from cytotoxic agents by modulation of .beta.-catenin signaling pathways
|
US20040219579A1
(en)
|
2003-02-19 |
2004-11-04 |
Natasha Aziz |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
CA2528669A1
(en)
|
2003-06-09 |
2005-01-20 |
The Regents Of The University Of Michigan |
Compositions and methods for treating and diagnosing cancer
|
ATE545658T1
(de)
|
2003-07-11 |
2012-03-15 |
Oncotherapy Science Inc |
Verfahren zur behandlung von synovialsarkom
|
US7329742B2
(en)
|
2003-09-04 |
2008-02-12 |
The Regents Of The University Of California |
Aptamers and methods for their in vitro selection and uses thereof
|
WO2005031003A1
(en)
|
2003-09-22 |
2005-04-07 |
The Regents Of The University Of California |
Mutations in wnt-frizzled signaling pathways associated with osteoarthritis
|
US6894522B2
(en)
|
2003-10-06 |
2005-05-17 |
International Business Machines Corporation |
Specific site backside underlaying and micromasking method for electrical characterization of semiconductor devices
|
AU2004290070A1
(en)
|
2003-11-12 |
2005-05-26 |
Biogen Idec Ma Inc. |
Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto
|
FR2867784B1
(fr)
|
2004-03-17 |
2006-06-09 |
Commissariat Energie Atomique |
Aptameres selectionnes a partir de cellules vivantes tumorales et leurs applications
|
US20050239134A1
(en)
|
2004-04-21 |
2005-10-27 |
Board Of Regents, The University Of Texas System |
Combinatorial selection of phosphorothioate single-stranded DNA aptamers for TGF-beta-1 protein
|
WO2005116236A2
(en)
|
2004-05-14 |
2005-12-08 |
The Regents Of The University Of California |
Methods for treating cancer using anti-wnt2 monoclonal antibodies and sirna
|
WO2006024497A1
(en)
|
2004-08-30 |
2006-03-09 |
Lonza Biologics Plc. |
Affinity- plus ion exchange- chromatography for purifying antibodies
|
WO2006036175A2
(en)
|
2004-09-21 |
2006-04-06 |
Rhode Island Hospital, A Lifespan-Partner |
Wnt proteins and detection and treatment of cancer
|
JP5025475B2
(ja)
|
2004-09-21 |
2012-09-12 |
ロード アイランド ホスピタル エー ライフスパン−パートナー |
Wntタンパク質ならびに癌の検出および治療の方法
|
US7867705B2
(en)
|
2004-09-21 |
2011-01-11 |
Rhode Island Hospital, A Lifespan-Partner |
Frizzled proteins and detection and treatment of cancer
|
ES2629397T3
(es)
|
2004-09-24 |
2017-08-09 |
Amgen Inc. |
Moléculas de Fc modificadas
|
DE102004050620A1
(de)
|
2004-10-13 |
2006-04-20 |
Eberhard-Karls-Universität Tübingen |
Monoklonaler Antikörper gegen Frizzled-Rezeptoren
|
US20070265246A1
(en)
*
|
2004-11-10 |
2007-11-15 |
Clevers Johannes C |
Treatment of an Intestinal Adenoma and/or Adenocarcinoma by Inhibition of Notch Pathway Activation
|
WO2006055635A2
(en)
|
2004-11-15 |
2006-05-26 |
Mount Sinai School Of Medicine Of New York University |
Compositions and methods for altering wnt autocrine signaling
|
ATE480642T1
(de)
|
2004-11-24 |
2010-09-15 |
Hoffmann La Roche |
Verfahren zur bestimmung von genotoxizität
|
US7635530B2
(en)
|
2005-03-21 |
2009-12-22 |
The Board Of Trustees Of The University Of Illinois |
Membraneless electrochemical cell and microfluidic device without pH constraint
|
JP2008542366A
(ja)
|
2005-05-30 |
2008-11-27 |
アストラゼネカ・アクチエボラーグ |
Fzd8モジュレーターを同定する方法および変形性関節症を処置するためのそのようなモジュレーターの使用
|
US20070014776A1
(en)
|
2005-06-09 |
2007-01-18 |
Gimeno Ruth E |
Identification of adiponutrin-related proteins as esterases and methods of use for the same
|
NZ565511A
(en)
*
|
2005-07-22 |
2011-03-31 |
Five Prime Therapeutics Inc |
Compositions and methods of treating disease with FGFR fusion proteins
|
US20070072238A1
(en)
|
2005-09-26 |
2007-03-29 |
Wyeth |
Wnt-frizzled chimera
|
BRPI0616589A2
(pt)
*
|
2005-09-28 |
2011-06-28 |
Zymogenetics Inc |
polipeptìdeo, e, métodos para produzir um anticorpo para um polipeptìdeo, para reduzir ou inibir a inflamação e para tratar um mamìfero afligido com uma doença inflamatória
|
EP1961065A4
(en)
|
2005-10-31 |
2009-11-11 |
Oncomed Pharm Inc |
COMPOSITIONS AND METHOD FOR DIAGNOSIS AND TREATMENT OF CANCER
|
US7723477B2
(en)
*
|
2005-10-31 |
2010-05-25 |
Oncomed Pharmaceuticals, Inc. |
Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
|
CA2628255C
(en)
|
2005-10-31 |
2016-04-19 |
The Regents Of The University Of Michigan |
Compositions and methods for treating and diagnosing cancer
|
DOP2006000277A
(es)
|
2005-12-12 |
2007-08-31 |
Bayer Pharmaceuticals Corp |
Anticuerpos anti mn y métodos para su utilización
|
WO2007070671A2
(en)
|
2005-12-16 |
2007-06-21 |
Regeneron Pharmaceuticals, Inc. |
Therapeutic methods for inhibiting tumor growth with dll4 antagonists
|
AR060017A1
(es)
|
2006-01-13 |
2008-05-21 |
Novartis Ag |
Composiciones y metodos de uso para anticuerpos de dickkopf -1
|
CA2641315A1
(en)
|
2006-02-06 |
2007-08-16 |
Tethys Bioscience, Inc. |
Osteoporosis associated markers and methods of use thereof
|
TW200800181A
(en)
|
2006-02-09 |
2008-01-01 |
Sankyo Co |
Pharmaceutical composition for anticancer
|
GB0603683D0
(en)
|
2006-02-23 |
2006-04-05 |
Novartis Ag |
Organic compounds
|
KR20090027218A
(ko)
|
2006-05-24 |
2009-03-16 |
바이엘 쉐링 파마 악티엔게젤샤프트 |
면역원성이 감소된, 고친화도 인간 및 인간화된 항-α5β1 인테그린 작용 블로킹 항체
|
MX2008015541A
(es)
|
2006-06-06 |
2008-12-18 |
Genentech Inc |
Anticuerpos anti-dll4 y metodos que los usan.
|
EP2029159A2
(en)
|
2006-06-06 |
2009-03-04 |
Genentech, Inc. |
Compositions and methods for modulating vascular development
|
WO2007145840A2
(en)
|
2006-06-13 |
2007-12-21 |
Oncomed Pharmaceuticals, Inc. |
Compositions and methods for diagnosing and treating cancer
|
JP5028635B2
(ja)
|
2006-06-21 |
2012-09-19 |
オンコセラピー・サイエンス株式会社 |
Fzd10に対する腫瘍標的化モノクローナル抗体とその使用
|
TW200815469A
(en)
|
2006-06-23 |
2008-04-01 |
Astrazeneca Ab |
Compounds
|
EP2526969A1
(en)
|
2006-09-07 |
2012-11-28 |
Stemline Therapeutics, Inc. |
Monitoring cancer stem cells
|
CN101600449A
(zh)
*
|
2006-09-08 |
2009-12-09 |
健泰科生物技术公司 |
Wnt拮抗剂及其在wnt介导的病症的诊断和治疗中的用途
|
CA2662041A1
(en)
*
|
2006-09-08 |
2008-03-13 |
Genentech, Inc. |
Wnt antagonists and their use in the diagnosis and treatment of wnt-mediated disorders
|
WO2008082730A2
(en)
|
2006-09-19 |
2008-07-10 |
Novartis Ag |
Biomarkers of target modulation, efficacy, diagnosis and/or prognosis for raf inhibitors
|
EA018260B1
(ru)
|
2006-09-29 |
2013-06-28 |
Онкомед Фармасьютикалз, Инк. |
Антитела к дельта-подобному лиганду 4 человека и их применение
|
EP2084296B1
(en)
|
2006-09-29 |
2015-08-05 |
Agendia N.V. |
High-throughput diagnostic testing using arrays
|
US20100041102A1
(en)
|
2006-11-07 |
2010-02-18 |
Ayesha Sitlani |
Antagonists of pcsk9
|
EP2084540A2
(en)
|
2006-11-14 |
2009-08-05 |
Novartis Ag |
Methods of treating, diagnosing or detecting cancer
|
RU2448979C2
(ru)
|
2006-12-14 |
2012-04-27 |
Ридженерон Фармасьютикалз, Инк. |
Антитела человека к дельта-подобному лиганду-4 человека
|
EP2120996A2
(en)
|
2006-12-20 |
2009-11-25 |
Vasgene Therapeutics, Inc. |
Methods for using and identifying modulators of delta-like 4
|
SI3345607T1
(sl)
|
2006-12-29 |
2023-03-31 |
Ossifi-Mab Llc |
Postopki spreminjanja rasti kosti z dajanjem antagonista ali agonista SOST ali WISE
|
US7691980B2
(en)
|
2007-01-09 |
2010-04-06 |
Bio-Rad Laboratories, Inc. |
Enhanced capacity and purification of antibodies by mixed mode chromatography in the presence of aqueous-soluble nonionic organic polymers
|
EP2125013A4
(en)
|
2007-01-26 |
2010-04-07 |
Bioinvent Int Ab |
DLL4 SIGNALING INHIBITOR AND ITS USES
|
EP2150544B1
(en)
|
2007-03-19 |
2016-01-13 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors
|
US20090082328A1
(en)
|
2007-05-11 |
2009-03-26 |
Bayer Schering Pharma Aktiengesellschaft |
Substituted phenylamino-benzene derivatives useful for treating hyper-proliferative disorders and diseases associated with mitogen extracellular kinase activity
|
WO2008157179A2
(en)
|
2007-06-12 |
2008-12-24 |
Genentech, Inc. |
N-substituted azaindoles and methods of use
|
WO2009010530A1
(en)
|
2007-07-18 |
2009-01-22 |
Novartis Ag |
Bicyclic heteroaryl compounds and their use as kinase inhibitors
|
CN101808516B
(zh)
|
2007-07-30 |
2013-08-28 |
阿迪生物科学公司 |
作为mek抑制剂的包括多晶型物的n-(芳氨基)磺酰胺衍生物和组合物、其使用方法和制备方法
|
CA2924418A1
(en)
|
2007-07-30 |
2009-02-05 |
Jean-Michel Vernier |
Derivatives of n-(arylamino) sulfonamides including polymorphs as inhibitors of mek as well as compositions, methods of use and methods for preparing the same
|
DK3156414T3
(da)
|
2007-09-26 |
2020-03-09 |
Intrexon Corp |
Syntetisk 5'utrs ekspressionsvektorer og fremgangsmåder til øgning af transgen ekspression
|
TWI489993B
(zh)
|
2007-10-12 |
2015-07-01 |
Novartis Ag |
骨硬化素(sclerostin)抗體組合物及使用方法
|
AU2008320823B2
(en)
|
2007-11-02 |
2013-01-17 |
Novartis Ag |
Molecules and methods for modulating low-density-lipoprotein receptor-related protein 6 (LRP6)
|
KR20100089869A
(ko)
|
2007-11-05 |
2010-08-12 |
노파르티스 아게 |
Wnt 활성화의 측정 및 wnt-관련 암의 치료를 위한 방법 및 조성물
|
JP5453290B2
(ja)
|
2007-11-12 |
2014-03-26 |
武田薬品工業株式会社 |
Mapk/erkキナーゼ阻害剤
|
US20090186396A1
(en)
|
2008-01-18 |
2009-07-23 |
Gagnon Peter S |
Enhanced purification of phosphorylated and nonphosphorylated biomolecules by apatite chromatography
|
US20110020368A1
(en)
|
2008-03-25 |
2011-01-27 |
Nancy Hynes |
Treating cancer by down-regulating frizzled-4 and/or frizzled-1
|
DE202008004821U1
(de)
|
2008-04-07 |
2008-06-12 |
Heil, Roland |
Siebdruckform
|
FR2936255B1
(fr)
|
2008-09-19 |
2010-10-15 |
Galderma Res & Dev |
Modulateurs de fzd2 dans le traitement de l'alopecie
|
US20130295106A1
(en)
|
2008-09-26 |
2013-11-07 |
Oncomed Pharmaceuticals, Inc. |
Frizzled-Binding Agents And Uses Thereof
|
AU2009296246B2
(en)
*
|
2008-09-26 |
2015-07-30 |
Oncomed Pharmaceuticals, Inc. |
Frizzled-binding agents and uses thereof
|
EP2343080B1
(en)
|
2008-09-30 |
2017-11-08 |
Kyowa Hakko Kirin Co., Ltd. |
PHARMACEUTICAL COMPOSITION FOR TREATING BONE DISEASES WHICH COMPRISES PROTEIN COMPRISING Frizzled1, Frizzled2 OR Frizzled7 EXTRACELLULAR CYSTEINE-RICH DOMAIN AND Fc PROTEIN
|
US20100169025A1
(en)
|
2008-10-10 |
2010-07-01 |
Arthur William T |
Methods and gene expression signature for wnt/b-catenin signaling pathway
|
CA2972379A1
(en)
|
2009-03-11 |
2010-09-16 |
Ardea Biosciences, Inc. |
Pharmaceutical combinations comprising rdea119/bay 869766 for the treatment of specific cancers
|
TWI535445B
(zh)
*
|
2010-01-12 |
2016-06-01 |
安可美德藥物股份有限公司 |
Wnt拮抗劑及治療和篩選方法
|
UY33227A
(es)
|
2010-02-19 |
2011-09-30 |
Novartis Ag |
Compuestos de pirrolopirimidina como inhibidores de la cdk4/6
|
US20130059851A1
(en)
|
2010-03-09 |
2013-03-07 |
Dana-Farber Cancer Institute, Inc. |
Methods of Diagnosing and Treating Cancer in Patients Having or Developing Resistance to a First Cancer Therapy
|
NZ602700A
(en)
|
2010-04-01 |
2014-10-31 |
Oncomed Pharm Inc |
Frizzled-binding agents and uses thereof
|
EP2585098B1
(en)
*
|
2010-06-28 |
2014-08-27 |
Five Prime Therapeutics, Inc. |
Fzd8 extracellular domains and fzd8 extracellular domain fusion molecules for use in treating obesity and obesity-related disorders
|
UY33469A
(es)
|
2010-06-29 |
2012-01-31 |
Irm Llc Y Novartis Ag |
Composiciones y metodos para modular la via de señalizacion de wnt
|
EP2632951B1
(en)
|
2010-10-27 |
2017-08-02 |
Amgen Inc. |
Dkk1 antibodies and methods of use
|
AU2013334790A1
(en)
|
2012-10-23 |
2015-04-30 |
Oncomed Pharmaceuticals, Inc. |
Methods of treating neuroendocrine tumors using Wnt pathway-binding agents
|
EP2950885B1
(en)
|
2013-02-04 |
2018-11-21 |
Oncomed Pharmaceuticals, Inc. |
Methods and monitoring of treatment with a wnt pathway inhibitor
|