AR011410A1 - Una formulacion liquida que contiene gonadotrofinas, un metodo para preparar una composicion liquida de gonadotrofinas, un cartucho que contiene una formulacion liquida esteril, un dispositivo para administrar la formulacion y utilizacion de la formulacion que contiene la gonadotrofinas para la elab - Google Patents
Una formulacion liquida que contiene gonadotrofinas, un metodo para preparar una composicion liquida de gonadotrofinas, un cartucho que contiene una formulacion liquida esteril, un dispositivo para administrar la formulacion y utilizacion de la formulacion que contiene la gonadotrofinas para la elabInfo
- Publication number
- AR011410A1 AR011410A1 ARP980100152A ARP980100152A AR011410A1 AR 011410 A1 AR011410 A1 AR 011410A1 AR P980100152 A ARP980100152 A AR P980100152A AR P980100152 A ARP980100152 A AR P980100152A AR 011410 A1 AR011410 A1 AR 011410A1
- Authority
- AR
- Argentina
- Prior art keywords
- formulation
- gonadotrophins
- liquid
- liquid formulation
- preparing
- Prior art date
Links
- 239000012669 liquid formulation Substances 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000007788 liquid Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 150000003568 thioethers Chemical class 0.000 abstract 2
- 102000006771 Gonadotropins Human genes 0.000 abstract 1
- 108010086677 Gonadotropins Proteins 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000002622 gonadotropin Substances 0.000 abstract 1
- 208000000509 infertility Diseases 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 231100000535 infertility Toxicity 0.000 abstract 1
- 229940124508 injectable medicine Drugs 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 150000002840 non-reducing disaccharides Chemical class 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- -1 sucrose Chemical class 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97200099 | 1997-01-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR011410A1 true AR011410A1 (es) | 2000-08-16 |
Family
ID=8227932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980100152A AR011410A1 (es) | 1997-01-15 | 1998-01-14 | Una formulacion liquida que contiene gonadotrofinas, un metodo para preparar una composicion liquida de gonadotrofinas, un cartucho que contiene una formulacion liquida esteril, un dispositivo para administrar la formulacion y utilizacion de la formulacion que contiene la gonadotrofinas para la elab |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US5929028A (https=) |
| EP (2) | EP0853945B1 (https=) |
| JP (1) | JP4353549B2 (https=) |
| KR (1) | KR100498531B1 (https=) |
| CN (1) | CN1165341C (https=) |
| AR (1) | AR011410A1 (https=) |
| AT (1) | ATE237348T1 (https=) |
| AU (1) | AU736339B2 (https=) |
| BR (1) | BR9800323B1 (https=) |
| CA (1) | CA2226803A1 (https=) |
| CZ (1) | CZ297419B6 (https=) |
| DE (2) | DE69813322T2 (https=) |
| DK (1) | DK0853945T3 (https=) |
| ES (1) | ES2196474T3 (https=) |
| FR (1) | FR10C0024I2 (https=) |
| HU (1) | HU227154B1 (https=) |
| ID (1) | ID19499A (https=) |
| IL (1) | IL122732A0 (https=) |
| LU (1) | LU91655I2 (https=) |
| MX (1) | MX9800438A (https=) |
| NO (3) | NO322509B1 (https=) |
| NZ (1) | NZ329572A (https=) |
| PL (1) | PL190103B1 (https=) |
| PT (1) | PT853945E (https=) |
| RU (1) | RU2203086C2 (https=) |
| SA (1) | SA98181124B1 (https=) |
| TR (1) | TR199800062A2 (https=) |
| TW (1) | TW518235B (https=) |
| ZA (1) | ZA9883B (https=) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL140984A0 (en) * | 1998-07-23 | 2002-02-10 | Lilly Co Eli | Fsh and fsh variant formulations, products and methods |
| US20030166525A1 (en) | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
| JP2007204498A (ja) * | 1999-03-01 | 2007-08-16 | Chugai Pharmaceut Co Ltd | 長期安定化製剤 |
| JP2000247903A (ja) * | 1999-03-01 | 2000-09-12 | Chugai Pharmaceut Co Ltd | 長期安定化製剤 |
| CN1360506A (zh) * | 1999-07-12 | 2002-07-24 | 格兰迪斯生物技术有限公司 | 生长激素配方 |
| CZ303274B6 (cs) * | 2000-02-22 | 2012-07-11 | Merck Serono Sa | Zpusob vycištení luteinizacního hormonu |
| US7256184B2 (en) * | 2000-10-16 | 2007-08-14 | Rodriguez Victorio C | Treatment of aging disorders in humans |
| AU2007200662A1 (en) * | 2001-08-30 | 2007-03-08 | Kirin-Amgen, Inc. | L-methionine as a stabilizer for NESP/EPO in HSA-free formulations |
| US20030104996A1 (en) * | 2001-08-30 | 2003-06-05 | Tiansheng Li | L-methionine as a stabilizer for NESP/EPO in HSA-free formulations |
| EP1346843A1 (en) * | 2002-03-22 | 2003-09-24 | Fuji Photo Film Co., Ltd. | Image forming method |
| CA2518268C (en) | 2003-03-04 | 2013-12-10 | Aspenbio, Inc. | Methods and kits for maintaining pregnancy, treating follicular cysts, and synchronizing ovulation using luteinizing hormone |
| DK1610822T4 (en) * | 2003-04-02 | 2019-01-14 | Ares Trading Sa | Liquid pharmaceutical FSH and LH formulations together with a nonionic surfactant |
| ES2358330T5 (es) * | 2003-04-02 | 2018-12-03 | Ares Trading S.A. | Formulaciones farmacéuticas líquidas de FSH y LH junto con un tensioactivo no iónico |
| US20040248784A1 (en) * | 2003-06-03 | 2004-12-09 | Marco Filicori | Unitary combinations of FSH and hCG |
| EP1638595B1 (en) * | 2003-06-20 | 2013-03-20 | Ares Trading S.A. | Freeze-dried fsh / lh formulations |
| JP4412989B2 (ja) * | 2003-12-15 | 2010-02-10 | 株式会社日立製作所 | 複数の記憶システムを有するデータ処理システム |
| KR100587535B1 (ko) * | 2004-02-04 | 2006-06-08 | 충남대학교산학협력단 | 재조합 hFSH 유전자 및 이를 내장하는 발현용 벡터 |
| TWI369401B (en) * | 2005-07-05 | 2012-08-01 | Ares Trading Sa | Serum-free culture medium for the production of recombinant gonadotropins |
| KR101105871B1 (ko) * | 2005-09-27 | 2012-01-16 | 주식회사 엘지생명과학 | 인 난포자극호르몬의 안정한 용액 제형 |
| US8137677B2 (en) * | 2005-10-06 | 2012-03-20 | Allergan, Inc. | Non-protein stabilized clostridial toxin pharmaceutical compositions |
| US8168206B1 (en) | 2005-10-06 | 2012-05-01 | Allergan, Inc. | Animal protein-free pharmaceutical compositions |
| WO2007056851A1 (en) * | 2005-11-17 | 2007-05-24 | Mount Sinai Hospital | Compositions and methods for enhancing ovulation inducing agents |
| US8946155B2 (en) | 2006-02-03 | 2015-02-03 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US10351615B2 (en) | 2006-02-03 | 2019-07-16 | Opko Biologics Ltd. | Methods of treatment with long-acting growth hormone |
| US9249407B2 (en) | 2006-02-03 | 2016-02-02 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US9458444B2 (en) | 2006-02-03 | 2016-10-04 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US20140113860A1 (en) | 2006-02-03 | 2014-04-24 | Prolor Biotech Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US8450269B2 (en) * | 2006-02-03 | 2013-05-28 | Prolor Biotech Ltd. | Long-acting growth hormone and methods of producing same |
| US10221228B2 (en) | 2006-02-03 | 2019-03-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US20150038413A1 (en) | 2006-02-03 | 2015-02-05 | Opko Biologics Ltd. | Long-acting polypeptides and methods of producing and administering same |
| US8048849B2 (en) | 2006-02-03 | 2011-11-01 | Modigene, Inc. | Long-acting polypeptides and methods of producing same |
| US20090261690A1 (en) * | 2006-09-25 | 2009-10-22 | Tomoaki Mashimo | Ultrasonic wave handling device and a microscopic in-tube inspection system |
| KR20080106636A (ko) * | 2007-06-04 | 2008-12-09 | 동아제약주식회사 | 사람 융모성 성선자극호르몬 함유 즉시 사용형 주사 용액 |
| EP2170268A2 (en) * | 2007-06-25 | 2010-04-07 | Amgen, Inc. | Compositions of specific binding agents to hepatocyte growth factor |
| DK2170942T3 (da) | 2007-06-28 | 2013-11-04 | Biogenerix Ag | Fsh-producerende celleklon |
| BRPI0818324B8 (pt) * | 2007-11-01 | 2021-05-25 | Merck Serono Sa | formulação líquida contendo hormônio luteinizante (lh) ou uma variante do mesmo, seu uso, sua forma de apresentação, processo para a sua preparação e composição farmacêutica |
| NZ586588A (en) * | 2008-02-08 | 2012-10-26 | Biogenerix Ag | Formulation of ( follice stimulating hormone) fsh and varients with benzalkonium chloride and benzyl alcohol |
| TWI488640B (zh) | 2008-04-16 | 2015-06-21 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| CN101347613B (zh) * | 2008-09-17 | 2011-10-26 | 上海天伟生物制药有限公司 | 几乎不含亚基的糖蛋白的组合物及其制备方法 |
| CN102309745B (zh) * | 2008-09-17 | 2013-05-08 | 上海天伟生物制药有限公司 | 一种卵泡刺激素冻干针剂 |
| KR101668502B1 (ko) | 2008-11-04 | 2016-10-21 | 아스카 세이야쿠 가부시키가이샤 | 난포자극호르몬 함유 수성 조성물 |
| US12203113B2 (en) | 2009-07-09 | 2025-01-21 | Opko Biologics Ltd. | Long-acting coagulation factors and methods of producing same |
| US9663778B2 (en) | 2009-07-09 | 2017-05-30 | OPKO Biologies Ltd. | Long-acting coagulation factors and methods of producing same |
| TWI532495B (zh) | 2009-10-05 | 2016-05-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| EP2325194A1 (en) | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Process for the purification of glycoproteins |
| EP2417982A1 (en) * | 2010-07-30 | 2012-02-15 | Ferring B.V. | Stabilization of gonadotropins |
| WO2012127500A2 (en) * | 2011-03-11 | 2012-09-27 | Sanzyme Limited | Composition for spermatogenesis |
| WO2012127501A2 (en) * | 2011-03-11 | 2012-09-27 | Sanzyme Limited | Composition for improving endometrial thickness during ovarian stimulation |
| PL2691119T3 (pl) | 2011-03-31 | 2019-01-31 | Ferring B.V. | Preparat farmaceutyczny |
| US8680086B2 (en) | 2011-04-15 | 2014-03-25 | Neuralight Hd, Llc | Methods for chronic pain management and treatment using HCG |
| US20120265129A1 (en) | 2011-04-15 | 2012-10-18 | Neuralight Hd, Llc | Methods for Chronic Pain Management and Treatment using HCG |
| BR112014001274A2 (pt) | 2011-07-18 | 2017-04-18 | Arts Biologics As | composto de hormônio luteinizante, e, composição farmacêutica |
| JO3092B1 (ar) | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
| HK1207564A1 (en) | 2012-04-19 | 2016-02-05 | Opko Biologics Ltd | Long-acting oxyntomodulin variants and methods of producing same |
| WO2014063071A1 (en) | 2012-10-18 | 2014-04-24 | Neuralight Hd, Llc | Treatment of depression and ptsd |
| HUE055348T2 (hu) | 2012-11-20 | 2021-11-29 | Opko Biologics Ltd | Eljárás polipeptidek hidrodinamikus térfogatának növelésére gonadotropin karboxil-terminális peptidekhez való kapcsolással |
| EP2974734B1 (en) | 2013-03-12 | 2018-10-10 | Sumitomo Dainippon Pharma Co., Ltd. | Liquid aqueous composition |
| EP2968391A1 (en) | 2013-03-13 | 2016-01-20 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
| US20150158926A1 (en) | 2013-10-21 | 2015-06-11 | Opko Biologics, Ltd. | Long-acting polypeptides and methods of producing and administering same |
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| EP3230309B1 (en) | 2014-12-10 | 2023-03-29 | OPKO Biologics Ltd. | Methods of producing long acting ctp-modified growth hormone polypeptides |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| PL3310347T3 (pl) | 2015-06-19 | 2021-12-27 | Opko Biologics Ltd. | Długo działające czynniki krzepnięcia i sposoby wytwarzania |
| GB201603280D0 (en) * | 2016-02-24 | 2016-04-13 | Ferring Bv | Stable liquid gonadotropin formulation |
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| KR102480965B1 (ko) | 2016-09-13 | 2022-12-26 | 알레간 인코포레이티드 | 안정화된 비단백질 클로스트리듐 독소 조성물 |
| US11110063B2 (en) | 2017-08-25 | 2021-09-07 | MAIA Pharmaceuticals, Inc. | Storage stable sincalide formulations |
| CA3140267A1 (en) | 2019-05-16 | 2020-11-19 | Ceva Sante Animale | Compositions and methods for increasing reproduction performance in non-human mammals using recombinant luteinizing hormone |
| CN114404575A (zh) * | 2020-12-07 | 2022-04-29 | 苏州智核生物医药科技有限公司 | 一种重组人促甲状腺素注射液 |
| CN117783545B (zh) * | 2023-12-28 | 2026-03-06 | 深圳市新产业生物医学工程股份有限公司 | 经封闭剂封闭的软质材料、容器、液态校准品及检测试剂盒 |
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| US4357934A (en) * | 1980-07-23 | 1982-11-09 | The Curators Of The University Of Missouri | Method of treating male infertility |
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| US5384132A (en) * | 1990-03-20 | 1995-01-24 | Akzo N.V. | Stabilized gonadotropin containing preparations |
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| US5272135A (en) * | 1991-03-01 | 1993-12-21 | Chiron Ophthalmics, Inc. | Method for the stabilization of methionine-containing polypeptides |
| IT1250075B (it) * | 1991-12-18 | 1995-03-30 | Serono Cesare Ist Ricerca | Composizioni farmaceutiche contenenti gonadotropine. |
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| PT814841E (pt) * | 1995-03-21 | 2002-03-28 | Applied Research Systems | Formulacoes liquidas de hcg |
-
1997
- 1997-12-23 IL IL12273297A patent/IL122732A0/xx not_active IP Right Cessation
- 1997-12-23 TW TW086119598A patent/TW518235B/zh not_active IP Right Cessation
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1998
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- 1998-01-12 ID IDP980030A patent/ID19499A/id unknown
- 1998-01-13 AT AT98200068T patent/ATE237348T1/de active
- 1998-01-13 NZ NZ329572A patent/NZ329572A/xx not_active IP Right Cessation
- 1998-01-13 ES ES98200068T patent/ES2196474T3/es not_active Expired - Lifetime
- 1998-01-13 DE DE69813322T patent/DE69813322T2/de not_active Expired - Lifetime
- 1998-01-13 DK DK98200068T patent/DK0853945T3/da active
- 1998-01-13 PT PT98200068T patent/PT853945E/pt unknown
- 1998-01-13 EP EP98200068A patent/EP0853945B1/en not_active Expired - Lifetime
- 1998-01-13 EP EP02079923A patent/EP1285665A1/en not_active Withdrawn
- 1998-01-13 DE DE122010000011C patent/DE122010000011I1/de active Pending
- 1998-01-13 CN CNB981041493A patent/CN1165341C/zh not_active Expired - Lifetime
- 1998-01-14 NO NO19980177A patent/NO322509B1/no not_active IP Right Cessation
- 1998-01-14 AU AU52059/98A patent/AU736339B2/en not_active Expired
- 1998-01-14 MX MX9800438A patent/MX9800438A/es active IP Right Grant
- 1998-01-14 PL PL98324279A patent/PL190103B1/pl unknown
- 1998-01-14 BR BRPI9800323-2A patent/BR9800323B1/pt not_active IP Right Cessation
- 1998-01-14 HU HU9800056A patent/HU227154B1/hu active Protection Beyond IP Right Term
- 1998-01-14 CA CA002226803A patent/CA2226803A1/en not_active Abandoned
- 1998-01-14 RU RU98100930/14A patent/RU2203086C2/ru active Protection Beyond IP Right Term
- 1998-01-14 KR KR10-1998-0000785A patent/KR100498531B1/ko not_active Expired - Lifetime
- 1998-01-14 JP JP00538998A patent/JP4353549B2/ja not_active Expired - Lifetime
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- 1998-01-15 TR TR1998/00062A patent/TR199800062A2/xx unknown
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- 1998-04-22 SA SA98181124A patent/SA98181124B1/ar unknown
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2010
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2021
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